Twenty Years of Pancreatic Surgery in Iceland

Twenty Years of Pancreatic Surgery in Iceland: a Retrospective Cohort Study

A retrospective analysis of patients undergoing pancreatic operations in Landspitali University Hospital, Reykjavik, Iceland, between 2003 and 2022.

Study Overview

• Status: Completed
• Conditions: Pancreatectomy; Pancreatoduodenectomy; Distal Pancreatectomy (DP)

• Study Type: Observational
• Enrollment (Actual): 244

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

All patients who have undergone pancreatic resection in Iceland between 2003-2022. For the secondary outcome of duodenal cancer, patients with duodenal cancer who did not undergo resection in the same time span will also be included.

Description

Inclusion Criteria:

• All patients who have undergone pancreatic resection in Iceland between 2003-2022.
• For the secondary outcome of duodenal cancer, patients with duodenal cancer who did not undergo resection in the same time span will also be included.

Exclusion Criteria: None.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Severe complications	2003-2022
Short-term mortality	2003-2022

Secondary Outcome Measures

Outcome Measure	Time Frame
Demographic, operative and postoperative data	2003-2022
Oncological data and survival among patients with pancreatic and periampullary cancer	2003-2022
Outcomes after pancreatic surgery among patients who underwent resection for cystic lesions	2003-2022
Comparison of patients who underwent minimally invasive distal pancreatectomy during the study period to those who underwent open distal resection.	2003-2022
Demographic and histopathological data as well as survival compared between patients with duodenal cancer who underwent resection and patients who did not.	2003-2022
Trends over time in the usage of pancreatic and minimally invasive surgery as well as changes in outcomes.	2003-2022

Collaborators and Investigators

• Sponsor: Linkoeping University
• Collaborators: Landspitali University Hospital

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2003
• Primary Completion (Actual): December 1, 2022
• Study Completion (Actual): December 1, 2022

Study Registration Dates

• First Submitted: December 12, 2024
• First Submitted That Met QC Criteria: December 12, 2024
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: December 19, 2024
• Last Verified: December 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: VSN-24-124

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: Not included in the ethical approval for the study.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No