The Effect Of Using Sticky Bone With Coronally Advanced Flap In Management Of Type 1 Gingival Recession
June 26, 2026 updated by: Shaimaa Mohamed Ibrahim Abd Elhalim, Minia University
the main goal of this clinical trial is to evaluate the effect of sticky bone with coronally advanced flap in management of gingival recession in comparison to coronally advanced flap alone
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
30
Phase
- Phase 2
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Minya Governorate
-
Minya, Minya Governorate, Egypt, 61511
- Minia University
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
- Selected patients of both sexes with age range 25-45 years old.
- Patients are systemically healthy based on questionnaire dental modification of Cornell index.
- O'Leary index (1972) is less than 10% (the surgical therapy is not initiated until the patient reaches the 10% level or less of plaque accumulation).
- Buccal recession defects are classified RT1 according to Cairo's classification (2011).
- Clinical indication and/or patient request for recession coverage.
Exclusion Criteria:
- Pregnant female.
- Smokers.
- Patients with special needs or with any mental problems.
- All patients are using any kind of medications that could interfere with healing of periodontal tissues. Such as chemotherapy and radiotherapy.
- Teeth with carious lesions.
- Rotated and extruded teeth.
- Patient undergone any prior periodontal surgery in the relevant region within year.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Quadruple
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: study group
participant will receive sticky bone with coronally advanced flap
|
using sticky bone with coronally advanced flap in treating the gingival recession
|
|
Active Comparator: control group
participants will undergo coronally advanced flap in treating gingival recession
|
using coronally advanced flap alone in treating gingival recession
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
recession depth
Time Frame: changes in millimeters from base line up to 6 months
|
is measured from CEJ to the gingival margin in millimeters.
|
changes in millimeters from base line up to 6 months
|
|
thickness of keratinized gingiva
Time Frame: changes in biotype in millimeters from base line to follow up after 6 months
|
thickness of the keratinized gingiva in the faciolingual direction (gingival biotype)
|
changes in biotype in millimeters from base line to follow up after 6 months
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Recession Width
Time Frame: changes in millimeters from base line to follow up after 6 months
|
the widest point from the mesial gingival margin to the distal gingival margin in millimeters
|
changes in millimeters from base line to follow up after 6 months
|
|
the height of keratinized gingiva
Time Frame: changes in millimeters from base line up to 6 months
|
the distance from the mucogingival junction to the gingival margin
|
changes in millimeters from base line up to 6 months
|
|
percentage of root coverage
Time Frame: changes in percentile from base line up to 6 months
|
it is the [pre-operative gingival recession depth - post-operative recession depth]/ [preoperative recession depth] * 100%
|
changes in percentile from base line up to 6 months
|
|
Probing pocket depth
Time Frame: changes in millimeters from base line up to 6 months
|
the distance from the gingival margin to base of pocket.
|
changes in millimeters from base line up to 6 months
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Study Chair: Mohamed AbdElmonem Ebrahem, Professor, Minia University
- Study Chair: Ahmed Abdallah Khalil, professor, Minia University
- Study Director: AyaAllah Kamal Abd El-al, lecturer, Minia University
- Principal Investigator: Shaimaa Mohamed Ibrahim, Minia University
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Ogata Y, Bui M, Griffin TJ, Hur Y. Use of Allograft with Platelet Concentrate in the Treatment of Multiple Miller Class III Gingival Recession Defects: Report of Three Cases. Int J Periodontics Restorative Dent. 2017 May/Jun;37(3):339-344. doi: 10.11607/prd.2673.
- Wang HL, Kimble K, Eber R. Use of bone grafts for the enhancement of a GTR-based root coverage procedure: a pilot case study. Int J Periodontics Restorative Dent. 2002 Apr;22(2):119-27.
- Sohn, D., B, H., J, K., Park WE, & Park CC. (2015). Utilization of autologous concentrated growth factors (CGF) enriched bone graft matrix(Sticky bone) and CGF-enriched fibrin membrane in implant dentistry. Jr Implant Adv Cli Dent.
- Mathur A, Jain M, Jain K, Samar M, Goutham B, Swamy PD, Kulkarni S. Gingival recession in school kids aged 10-15 years in Udaipur, India. J Indian Soc Periodontol. 2009 Jan;13(1):16-20. doi: 10.4103/0972-124X.51889.
- Louis F. Rose, D. M. (2006). Surgical Therapies for the Treatment of Gingival Recession. Inside dentistry.
- Kimble KM, Eber RM, Soehren S, Shyr Y, Wang HL. Treatment of gingival recession using a collagen membrane with or without the use of demineralized freeze-dried bone allograft for space maintenance. J Periodontol. 2004 Feb;75(2):210-20. doi: 10.1902/jop.2004.75.2.210.
- Hadziabdic, N. (2022). PRF and Sticky Bone as Regenerative Materials in Oral Surgery. IntechOpen. doi:10.5772/intechopen.108807
- Ghoderao D, Rathod S, Kolte AP, Bawankar P, Jadhav A. Randomized, controlled clinical trial to evaluate efficacy of sticky bone and concentrated growth factor in the management of intrabony defects: 12 months follow-up study. Dent Res J (Isfahan). 2022 Aug 16;19:67. eCollection 2022.
- Kapa BP, N K S, G V G, Mehta DS. Coronally Advanced Flap Combined With Sticky Bone and i-PRF-Coated Collagen Membrane to Treat Single Maxillary Gingival Recessions: Case Series. Clin Adv Periodontics. 2022 Sep;12(3):147-151. doi: 10.1002/cap.10164. Epub 2021 May 15.
- Chatterjee A, Sharma E, Gundanavar G, Subbaiah SK. Treatment of multiple gingival recessions with vista technique: A case series. J Indian Soc Periodontol. 2015 Mar-Apr;19(2):232-5. doi: 10.4103/0972-124X.145836.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
March 1, 2025
Primary Completion (Actual)
September 25, 2025
Study Completion (Actual)
November 30, 2025
Study Registration Dates
First Submitted
March 4, 2025
First Submitted That Met QC Criteria
March 7, 2025
First Posted (Actual)
March 12, 2025
Study Record Updates
Last Update Posted (Actual)
June 30, 2026
Last Update Submitted That Met QC Criteria
June 26, 2026
Last Verified
March 1, 2025
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 870
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
product manufactured in and exported from the U.S.
No
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