Evaluating the Effects of Psychological Stress on Salivary Biomarkers in Pediatric Patients Visiting Pediatric and General Dental Clinic

Evaluating the Effects of Psychological Stress on Salivary Biomarkers in Pediatric Patients

the goal of this study is to test the effect of psychological stress on pediatric patients visiting specialized and general dental clinic by measure salivary cortisol and salivary alpha amylase and by use children fear survey schedule -dental subscale .

80 male subjects will be enrolled in this study between 4-6 years old with first dental visit ,40 subjects visiting specialized pediatric dental clinic to see the effect of specific environment and attitude of dentist on child stress ,and 40 subjects visiting general dental clinic with normal environment and general dentist .

the method of study is by taking two saliva sample from child , first when he will enter the clinic at reception and second after half hour when he will diagnosed without any type of treatment.

Study Overview

• Status: Not yet recruiting
• Conditions: Salivary Alpha Amylase; Salivary Cortisol
• Intervention / Treatment: Behavioral: to compare the effect of environment and attitude of dentist in children visiting specialized pediatric dental clinic and general dental clinic .

• Study Type: Observational
• Enrollment (Estimated): 80

Contacts and Locations

• Study Contact: Name: Donya ali abdalkadim, B.D.S; Phone Number: +9647735181734; Email: danyaali@uomustansiriyah.edu.iq

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

male children from 4-6 years old with first dental clinic

Description

Inclusion Criteria:

• male
• 4-6 years old
• first dental visit
• patients with no systemic disease

Exclusion Criteria:

• medically compressed patient
• patients with systemic disease

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
salivary alpha amylase	measure salivary alpha amylase before and after half hour to see if the environment and attitude of dentist effect on salivary alpha amylase hormone.	Baseline: saliva collection for cortisol and salivary alpha amylase measurement. up to half hour :saliva collection will be performed again as described at base line visit.
salivary cortisol	measure salivary cortisol before and after half hour to see if the environment and attitude of dentist effect on cortisol hormone.	Baseline: saliva collection for cortisol and salivary alpha amylase measurement. up to half hour :saliva collection will be performed again as described at base line visit.

Collaborators and Investigators

• Sponsor: Al-Mustansiriyah University

Study record dates

Study Major Dates

• Study Start (Estimated): April 15, 2025
• Primary Completion (Estimated): May 15, 2025
• Study Completion (Estimated): June 15, 2025

Study Registration Dates

• First Submitted: March 26, 2025
• First Submitted That Met QC Criteria: April 5, 2025
• First Posted (Actual): April 9, 2025

Study Record Updates

• Last Update Posted (Actual): April 9, 2025
• Last Update Submitted That Met QC Criteria: April 5, 2025
• Last Verified: March 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Behavioral Symptoms; Stress, Psychological
• Other Study ID Numbers: AL- Mustansiriyah University

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No