Clinical and Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births

Suleyman Demirel University Faculty of Dentistry Pediatric Dentistry Department

Clinical and radiographic evaluation of oral findings in children of multiple and single births

Study Overview

• Status: Completed
• Conditions: Oral Findings in Children of Multiple and Single Births; Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births
• Intervention / Treatment: Other: The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births

Detailed Description

In this study, the study groups comprised MZ and DZ twin pairs, triplets and singletons between the ages of 2 and 17 who attended the Department of Pediatric Dentistry at Suleyman Demirel University between January 2018 and September 2020. Twins and triplets who had developmental anomalies such as cleft lip and palate, premature tooth loss, systemic diseases or syndromes that could influence oral health or had already undergone or were undergoing orthodontic therapy, as well as those whose family did not give consent, were excluded from the study.

All children were assessed by the same experienced pedodontist (E.O.) to avoid interexaminer variability. The oral examination was performed using sterile mouth mirror and probe. The prevalence of dental caries was recorded using dmft index (decayed, missing and filled teeth) in primary dentition and DMFT index (Decayed, Missing and Filled teeth) in permanent dentition. When evaluating patients over 6 years old, the missing tooth component was not included in the primary dft scores.

Oral hygiene practices, such as tooth brushing frequency and the children's past or present oral habits (digit sucking, nail biting, tongue thrust, bruxism, lip biting, pencil biting, cheek biting and mouth breathing), were also recorded.

The primary molar relationships were evaluated as flush terminal plane and mesial and distal step. The permanent molar relationships were recorded as Class I, Class II (Division 1 and 2) and Class III. Occlusal traits such as increased overjet, deep bite, open bite and anterior and posterior crossbite were recorded as present (1) or absent (0) with the help of a dental probe

• Study Type: Interventional
• Enrollment (Actual): 690
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Isparta, Turkey, 32260
    • Suleyman Demirel University Faculty of Dentistry Pediatric Dentistry Department
  • Isparta, Turkey
    • Esra

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 2 years to 17 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Twins, triplets and singletons who had not

  • developmental anomalies such as cleft lip and palate
  • premature tooth loss
  • systemic diseases or syndromes that could influence oral health
  • already undergone or were undergoing orthodontic therapy

Exclusion Criteria:

• Twins, triplets and singletons who had

  • developmental anomalies such as cleft lip and palate
  • premature tooth loss
  • systemic diseases or syndromes that could influence oral health
  • already undergone or were undergoing orthodontic therapy
  • those whose family did not give consent

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Diagnostic
• Allocation: Non-Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Other: Multiple births (twins and triplets); Twins and triplets who had developmental anomalies such as cleft lip and palate, premature tooth loss, systemic diseases or syndromes that could influence oral health or had already undergone or were undergoing orthodontic therapy, as well as those whose family did not give consent, were excluded from the study	Other: The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births; The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births
Other: Singletons; Singletons who had developmental anomalies such as cleft lip and palate, premature tooth loss, systemic diseases or syndromes that could influence oral health or had already undergone or were undergoing orthodontic therapy, as well as those whose family did not give consent, were excluded from the study.	Other: The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births; The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Clinical examination of dental caries	The prevalence of dental caries was recorded using dmft index (decayed, missing and filled teeth) in primary dentition and DMFT index (Decayed, Missing and Filled teeth) in permanent dentition. When evaluating patients over 6 years old, the missing tooth component was not included in the primary dft scores.	Baseline
Evaluation of molar relationship	The primary molar relationships were evaluated as flush terminal plane and mesial and distal step. The permanent molar relationships were recorded as Class I, Class II (Division 1 and 2) and Class III	Baseline
Number of participants with oral habits	the children's past or present oral habits (digit sucking, nail biting, tongue thrust, bruxism, lip biting, pencil biting, cheek biting and mouth breathing) were recorded.	Baseline

Collaborators and Investigators

• Sponsor: Suleyman Demirel University
• Investigators: Principal Investigator: Esra Oz, Suleyman Demirel University Faculty of Dentistry Pediatric Dentistry Department

Study record dates

Study Major Dates

• Study Start (Actual): January 10, 2018
• Primary Completion (Actual): September 10, 2020
• Study Completion (Actual): September 10, 2021

Study Registration Dates

• First Submitted: January 2, 2021
• First Submitted That Met QC Criteria: January 4, 2021
• First Posted (Actual): January 6, 2021

Study Record Updates

• Last Update Posted (Actual): July 7, 2022
• Last Update Submitted That Met QC Criteria: July 4, 2022
• Last Verified: July 1, 2022

More Information

Terms related to this study

• Keywords: oral habits; twins; dental caries; multiple births; singletons
• Additional Relevant MeSH Terms: Anti-Infective Agents; Dermatologic Agents; Antifungal Agents; Keratolytic Agents; Salicylic Acid
• Other Study ID Numbers: 232

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No