- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07350434
Hip Abduction and Adduction During Neurodynamic Stretching (HIPROT)
April 27, 2026 updated by: Nicolas Babault, University of Burgundy
The Acute Effects of Neurodynamic Stretching on the Shear Wave Velocity: the Effects of Hip Adduction and Abduction
Neurodynamic mobilization techniques are widely applied in rehabilitation and physiotherapy to enhance the mobility and function of peripheral nerves.
Two main approaches are distinguished : Nerve tensioning and nerve flossing.
They both involve proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress.
However, contradictory findings following neurodynamic stretching highlighted the current lack of consensus regarding the position that should be used.
Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes.
Accordingly, the primary objective of the present study was to determine the immediate effect of two hip positions (adduction vs. abduction) during neurodynamic flossing techniques on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE, a form of ultrasonography).
Study Overview
Status
Recruiting
Conditions
Intervention / Treatment
Detailed Description
Neurodynamic mobilization techniques are frequently applied in rehabilitation settings to enhance the mobility and function of peripheral nerves, particularly in the management of neuropathic pain such as carpal tunnel syndrome, radiculopathies, or sciatica.
Two main approaches are distinguished.
Nerve tensioning involves maintaining the nerve stretched at the end of the joint range of motion with relatively limited excursion.
It is similar to a static stretching intervention but with distal (ankle) and proximal (cervical) tensions.
Nerve flossing (also termed gliding or sliders), consists of alternating proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress.
Both techniques appear efficient.
However, contradictory findings following neurodynamic stretching highlighted the current lack of consensus regarding the angular position that could be used.
For instance, hip rotations or hip adduction could impact muscle or nerve tissue changes, particularly in healthy tissues.
Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes.
Performed in patients, healthy or athletes, no study has compared different hip positions.
Accordingly, the primary objective of the present study was to determine the immediate effect of two hip positions (adduction vs. abduction) during neurodynamic flossing techniques on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE, a form of ultrasonography).
This method has been shown reliable to provide non-invasive real-time assessments of soft tissues elastic properties.
Study Type
Interventional
Enrollment (Estimated)
12
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Nicolas Babault
- Phone Number: +33380396743
- Email: nicolas.babault@ube.fr
Study Contact Backup
- Name: Carole Cometti
- Phone Number: +33389396789
- Email: carole.cometti@ube.fr
Study Locations
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Dijon, France
- Recruiting
- Universite Bourgogne Europe - faculty of sports sciences
-
Contact:
- Nicolas Babault
- Phone Number: +33380396743
- Email: nicolas.babault@ube.fr
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- healthy
- physical active
- no injuries (lower limb or back pain) in the past 3 months
Exclusion Criteria:
- Specific lower limb (hamstring) injuries in the past 2 years
- Not restraining activity 24h before participation
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Other
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
No Intervention: No intervention (neutral)
No intervention with measurements in neutral position
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|
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No Intervention: No intervention (adduction)
No intervention with measurements in adduction position
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No Intervention: No intervention (abduction)
No intervention with measurements in abduction position
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Active Comparator: Neurodynamic (neutral)
The hip was positioned neutral (alignment between the lower limb and the trunk).
|
Neurodynamic flossing was applied at pain threshold on hamstring muscles and repeated 5 times during 60s at the point of pain.
During the neurodynamic conditions, head and ankle movement permitted to mobilize nerve tissues.
Flossing is the alternation of these movements every 2 seconds.
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|
Experimental: Neurodynamic (adduction)
The hip was positioned in adduction and the neurodynamic stretch was applied.
|
Neurodynamic flossing was applied at pain threshold on hamstring muscles and repeated 5 times during 60s at the point of pain.
During the neurodynamic conditions, head and ankle movement permitted to mobilize nerve tissues.
Flossing is the alternation of these movements every 2 seconds.
|
|
Experimental: Neurodynamic (abduction)
The hip was positioned in abduction and the neurodynamic stretch was applied.
|
Neurodynamic flossing was applied at pain threshold on hamstring muscles and repeated 5 times during 60s at the point of pain.
During the neurodynamic conditions, head and ankle movement permitted to mobilize nerve tissues.
Flossing is the alternation of these movements every 2 seconds.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Nerve shear wave velocity using elastography in neutral position
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
Shear wave velocity of the sciatic nerve will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography".
Briefly, the ultrasound probe will deliver an ultrasound wave.
The propagation speed (called '"shear wave velocity") will be measured by the same probe.
The greater the velocity is, the harder the tissue is.
The hip position was neutral (alignment between the lower limb and the trunk).
|
Before the intervention and at the end (immediately after) the intervention
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Hamstring force
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
Maximal torque during a maximal voluntary hamstring contraction
|
Before the intervention and at the end (immediately after) the intervention
|
|
passive knee extension
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
The final passive range of motion of the hamstring muscles
|
Before the intervention and at the end (immediately after) the intervention
|
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Global flexibility
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
the stand and reach test to evaluate flexibility (in centimeters)
|
Before the intervention and at the end (immediately after) the intervention
|
|
Slump test
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
Seated flexibility using the slump test (in degrees)
|
Before the intervention and at the end (immediately after) the intervention
|
|
discomfort
Time Frame: At the end (immediately after) the intervention
|
rating of perceived discomfort during the intervention (from 1 to 10, no discomfort to maximal discomfort, respectively)
|
At the end (immediately after) the intervention
|
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Nerve shear wave velocity using elastography in experimental position
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
Shear wave velocity of the sciatic nerve will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography".
Briefly, the ultrasound probe will deliver an ultrasound wave.
The propagation speed (called '"shear wave velocity") will be measured by the same probe.
The greater the velocity is, the harder the tissue is.
The hip position was the experimental position (i.e., adduction or abduction depending on the randomisation).
|
Before the intervention and at the end (immediately after) the intervention
|
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Muscle shear wave velocity using elastography in neutral position
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
Shear wave velocity of the biceps femoris muscle will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography".
Briefly, the ultrasound probe will deliver an ultrasound wave.
The propagation speed (called '"shear wave velocity") will be measured by the same probe.
The greater the velocity is, the harder the tissue is.
The hip position was neutral (alignment between the lower limb and the trunk).
|
Before the intervention and at the end (immediately after) the intervention
|
|
Muscle shear wave velocity using elastography in the experimental position
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
Shear wave velocity of the biceps femoris muscle will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography".
Briefly, the ultrasound probe will deliver an ultrasound wave.
The propagation speed (called '"shear wave velocity") will be measured by the same probe.
The greater the velocity is, the harder the tissue is.
The hip position was the experimental position (i.e., adduction or abduction depending on the randomisation).
|
Before the intervention and at the end (immediately after) the intervention
|
|
Biceps femoris electromyographic activity
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
Electromyographic activity of biceps femoris muscle
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Before the intervention and at the end (immediately after) the intervention
|
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Semitendinosus electromyographic activity
Time Frame: Before the intervention and at the end (immediately after) the intervention
|
Electromyographic activity of semitendinosus
|
Before the intervention and at the end (immediately after) the intervention
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Nicolas Babault, universite bourgogne europe
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
February 1, 2026
Primary Completion (Actual)
February 10, 2026
Study Completion (Estimated)
June 30, 2026
Study Registration Dates
First Submitted
January 9, 2026
First Submitted That Met QC Criteria
January 9, 2026
First Posted (Actual)
January 20, 2026
Study Record Updates
Last Update Posted (Actual)
April 28, 2026
Last Update Submitted That Met QC Criteria
April 27, 2026
Last Verified
April 1, 2026
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- CEP2601
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
YES
IPD Plan Description
data freely available in online websites
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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