- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07575074
OKT With Gaze and Postural Stabilization on Vertigo, MS and QOL in VBH
May 4, 2026 updated by: Riphah International University
Effects of Optokinetic Training With Gaze and Postural Stabilization on Vertigo, Motion Sickness and Quality of Life in Vestibular Hypofunction
The objective of this study will evaluate the effects of optokinetic training combined with postural stabilization and gaze stability exercises on motion sickness, balance, gaze stability, and quality of life in individuals with vestibular hypofunction.
Study Overview
Status
Not yet recruiting
Conditions
Intervention / Treatment
Detailed Description
A randomized clinical trial will be conducted with 32 participants assigned to two groups: Group A (breathing and aerobic exercises) and Group B (optokinetic training combined with postural stabilization and gaze stability exercises).
Data will be collected using the Motion Sickness Susceptibility Questionnaire (MSSQ), Berg Balance Scale (BBS), Dynamic Visual Acuity Test for Gaze Stability, and Head Impulse Test.
Statistical analysis will be performed by SPSS.
Study Type
Interventional
Enrollment (Estimated)
32
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Muneeb Khan, PhD
- Phone Number: 923367993611
- Email: muneeb.khan@riphah.edu.pk
Study Locations
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Punjab Province
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Lahore, Punjab Province, Pakistan, 54500
- Ittefaq Hospital Lahore
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Contact:
- Javeria Ghazal, MSNMPT
- Phone Number: +923335154664
- Email: javeria.ghazal@riphah.edu.pk
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Principal Investigator:
- Asad Shahzad Mir, MsNMPT
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
• Male and female patients age 20 and 40 years
- Passengers who have motion sickness during travelling
- Patients of vestibular migraine who experience motion sickness
- Participants experiencing vertigo, dizziness or imbalance related to vestibular hypofunction over the past three months
Exclusion Criteria:
• Patients who have seasickness and simulator sickness excluded.
- Patients having vestibular disease and chronic neurological disease.
- Participants who have completed formal vestibular rehabilitation in last 6 months excluded
- Patients with severe visual impairments and orthopedic conditions excluded.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Group A Habituation exercises
Group A performed a regime of Habituation exercises five times per week to improve overall wellness and reduce baseline symptoms of motion sickness
|
Habituation exercises five times per week to improve overall wellness and reduce baseline symptoms of motion sickness (38).
Each session, lasting approximately 20-25 minutes, involved exercises conducted for 20 minutes per day, five times a week.
Each session, lasting approximately 30-45 minutes, included low-intensity breathing exercises aimed at promoting relaxation and moderate-intensity aerobic activities, such as walking or cycling, at 50-60% of the participant's maximum heart rate.
|
|
Experimental: Group B Optokinetic training protocol
Group B underwent a structured optokinetic training protocol combined with postural stabilization and gaze stability exercises, targeting both gaze and postural control systems.
|
10-minute warm-up, followed by 20-25 minutes of moderate-intensity optokinetic exercises (viewing controlled moving visual patterns), postural exercises involving controlled head and body movements to engage the vestibular system, and gaze stability exercises, which require focusing on a stationary target during head movements to improve the vestibulo-ocular reflex.
The session concluded with a 10-15-minute cool-down to aid relaxation.
These sessions continued for 12 weeks
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Motion sickness susceptibility questionnaire
Time Frame: 8th week
|
The Motion Sickness Susceptibility Questionnaire (MSSQ) is a widely used tool that assesses an individual's predisposition to motion sickness in various environments, such as vehicles, amusement rides, and virtual reality.
|
8th week
|
|
Berg balance scale
Time Frame: 8th week
|
The Berg Balance Scale (BBS) is a reliable clinical tool used to assess balance in individuals, particularly older adults and those with balance impairments.
It includes 14 tasks each scored from 0 (cannot perform) to 4 (performs independently).
The BBS has a maximum score of 56, and most of the patients show a low fall risk of 41 to 56 scores, medium risk of 21 to 40 scores, and a high risk of 0 to 20 scores.
|
8th week
|
|
Dynamic visual acuity test for gaze stability
Time Frame: 8th week
|
The Dynamic Visual Acuity (DVA) Test is a widely used clinical test to assess gaze stability, particularly in individuals with vestibular dysfunction.
It evaluates a person's ability to maintain clear vision during head movements, which requires stable gaze control.
The test involves reading porotype letters or symbols displayed on a screen, first in a stationary position and then while moving the head horizontally and vertically at a standardized speed (usually around 2 Hz)
|
8th week
|
|
Head impulse test
Time Frame: 8th week
|
The Head Impulse Test (HIT) is a diagnostic tool used to evaluate the function of the vestibulo-ocular reflex (VOR), essential for maintaining gaze stability during rapid head movements.
In this test, a clinician rapidly and unpredictably turns the patient's head to the left or right while the patient focuses on a stationary target, typically the clinician's nose.
For a healthy VOR, the eyes should remain fixed on the target despite the head movement
|
8th week
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Javeria Ghazal, MSNMPT, Riphah International University
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Estimated)
May 15, 2026
Primary Completion (Estimated)
August 15, 2026
Study Completion (Estimated)
September 14, 2026
Study Registration Dates
First Submitted
February 22, 2026
First Submitted That Met QC Criteria
May 4, 2026
First Posted (Actual)
May 8, 2026
Study Record Updates
Last Update Posted (Actual)
May 8, 2026
Last Update Submitted That Met QC Criteria
May 4, 2026
Last Verified
May 1, 2026
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- REC/RCR & AHS/24/02100
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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