Perioperative Safety and Long-Term Outcomes of Mesh Repair in Nonagenarians Undergoing Elective Inguinal Hernia Repair

Perioperative Safety and Long-Term Outcomes of Mesh Repair in Nonagenarians Undergoing Elective Inguinal Hernia Repair: A Single-Center Retrospective Cohort Study

To evaluate the clinical characteristics, postoperative outcomes, and factors associated with Clavien-Dindo grade ≥II complications in nonagenarians undergoing elective inguinal hernia repair. Preoperative, intraoperative, and postoperative data of nonagenarians who underwent elective inguinal hernia repair were collected. The primary outcome was Clavien-Dindo grade ≥II complications. Univariable logistic regression was used to identify associated factors.

Study Overview

• Status: Not yet recruiting
• Conditions: Inguinal Hernia Repair

Detailed Description

We included patients aged 90 years or older who underwent elective inguinal hernia repair at Huadong Hospital, Fudan University, between 2013 and 2025. Patients were excluded if they underwent emergency surgery for incarcerated or strangulated hernia. Patients were also excluded if incomplete data, or valid follow-up information was unavailable.

Patient data were collected from inpatient medical records, anesthesia records, nursing records, and follow-up records. Preoperative variables included age, sex, body mass index, functional status, American Society of Anesthesiologists class, comorbidities, and hernia-related characteristics. Intraoperative variables included anesthesia type, operative time, surgical approach, procedure type, mesh use, concomitant procedures, drain placement, and urinary catheterization. Postoperative variables included length of hospital stay, postoperative intensive care unit admission, postoperative complications, 30-day readmission, 30-day reoperation, in-hospital mortality, 30-day mortality, recurrence, chronic pain, reoperation for recurrence, and all-cause mortality during follow-up.

• Study Type: Observational
• Enrollment (Estimated): 150

Contacts and Locations

• Study Contact: Name: HEKAI SHI; Phone Number: +8618580290227; Email: 25111280019@m.fudan.edu.cn

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patients aged 90 years or older who underwent elective inguinal hernia repair

Description

Inclusion Criteria: patients aged 90 years or older who underwent elective inguinal hernia repair -

Exclusion Criteria: Patients underwent emergency surgery for incarcerated or strangulated hernia. Patients were also excluded if incomplete data, or valid follow-up information was unavailable.

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Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
nonagenarians; elective inguinal hernia repair

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Clavien-Dindo grade ≥II complications	The Clavien-Dindo classification grades complications according to the intensity of treatment required. Grade II or higher complications generally include events requiring pharmacologic therapy, interventional treatment, surgery, or resulting in death.	30 days

Collaborators and Investigators

• Sponsor: Fudan University

Study record dates

Study Major Dates

• Study Start (Estimated): June 1, 2026
• Primary Completion (Estimated): June 14, 2026
• Study Completion (Estimated): June 15, 2026

Study Registration Dates

• First Submitted: May 16, 2026
• First Submitted That Met QC Criteria: May 16, 2026
• First Posted (Actual): May 22, 2026

Study Record Updates

• Last Update Posted (Actual): May 22, 2026
• Last Update Submitted That Met QC Criteria: May 16, 2026
• Last Verified: May 1, 2026

More Information

Terms related to this study

• Keywords: Inguinal hernia; functional status; mesh repair; Clavien-Dindo classification; nonagenarians
• Additional Relevant MeSH Terms: Pathological Conditions, Anatomical; Hernia; Hernia, Abdominal; Pathological Conditions, Signs and Symptoms; Hernia, Inguinal
• Other Study ID Numbers: HuadongHosptialHernia03

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No