Nasal Surgery in Snoring and Obstructive Sleep Apnea

June 1, 2026 updated by: Asmaa Abdullah El Muhammady Ebrahim, Al-Azhar University

Role of Nasal Surgery in Snoring and Obstructive Sleep Apnea

This study aimed to evaluate the effect of isolated nasal surgery on sleep-disordered breathing, particularly apnea-hypopnea index (AHI) and snoring index (SI), Apnea index (AI) and minimal arterial oxygen saturation (MAO2) in adults with obstructive sleep apnea syndrome (OSAS) and nasal obstruction.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Snoring is the noisy breathing that occurs throughout sleep, resulting from the vibration of the structures in the oral cavity, including the soft palate, uvula, tonsils, base of the tongue, epiglottis, as well as pharyngeal walls.

Obstructive sleep apnea syndrome (OSAS) is a respiratory sleep disorder distinguished by repeated episodes of partial or total occlusion of the upper airways throughout sleep. This blockage is typically associated with a decrease (hypopnea) or total cessation (apnea) of airflow in the upper airways, and sustained thoracic-diaphragmatic respiratory movements.

Study Type

Interventional

Enrollment (Actual)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Cairo, Egypt, 11651
        • Al-Azhar University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Age above 18 years.
  • Both sexes.
  • Patients with anatomical nasal obstruction due to septal deviation, hypertrophied inferior turbinate (HIT), or nasal polyps refractory to medical treatment.
  • Presence of snoring and obstructive sleep apnea (OSA).
  • Fitness for surgery.

Exclusion Criteria:

  • Central or mixed sleep apnea.
  • Previous nasal surgery.
  • Unfitness for surgery.
  • Pathological obesity.
  • History of cardiopulmonary disease or asthma.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Group I
Patients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy.
Procedure: Septoplasty with partial inferior turbinectomy
Patients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy.
Experimental: Group II
Patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy.
Procedure: Nasal polypectomy
Patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy.
Experimental: Group III
Patients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone.
Procedure: Partial inferior turbinectomy
Patients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Apnea-Hypopnea Index
Time Frame: 3 months postoperatively
The Apnea-Hypopnea Index (AHI) is a critical metric used to diagnose and rank the severity of sleep apnea. It measures the average number of times your breathing completely stops (apneas) or becomes severely shallow (hypopneas) per hour of sleep.
3 months postoperatively

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Snoring index
Time Frame: 3 months postoperatively
The snoring index was defined as the number of snoring episodes divided by the hours of total sleep time
3 months postoperatively

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Al-Azhar University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 1, 2022

Primary Completion (Actual)

July 1, 2024

Study Completion (Actual)

July 1, 2024

Study Registration Dates

First Submitted

May 23, 2026

First Submitted That Met QC Criteria

June 1, 2026

First Posted (Actual)

June 3, 2026

Study Record Updates

Last Update Posted (Actual)

June 3, 2026

Last Update Submitted That Met QC Criteria

June 1, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 1225

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

The data will be available upon a reasonable request from the corresponding author after the end of study for one year.

IPD Sharing Time Frame

After the end of study for one year.

IPD Sharing Access Criteria

The data will be available upon a reasonable request from the corresponding author.

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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