Longitudinal Evaluation of Preoperative eHealth Literacy and Nutritional Index on Early Functional Recovery After Fragility Fractures

The integration of digital technologies into chronic disease rehabilitation has transformed people care, yet the specific impact of electronic health literacy on early functional outcomes in fragility fracture people remains underexplored. This study investigates the association between preoperative eHealth literacy and both preoperative and early postoperative functional outcomes in people with fragility fractures.

Study Overview

• Status: Completed
• Conditions: Fragility Fracture

• Study Type: Observational
• Enrollment (Actual): 353

Contacts and Locations

Study Locations

• China
  • Shandong
    • Jinan, Shandong, China, 250000
      • Shandong University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

• People diagnosed with fragility fractures according to the clinical "Primary Osteoporosis Diagnosis and Treatment Guidelines (2022 Edition)"[17] and based on the clinical diagnosis；

  • People who have undergone conventional surgical treatment；

    • People who are conscious and able to communicate normally； ④ People who have provided informed consent and voluntarily participate in this study； ⑤ People aged ≥18 years.

Description

Inclusion Criteria:

• People diagnosed with fragility fractures according to the clinical "Primary Osteoporosis Diagnosis and Treatment Guidelines (2022 Edition)"[17] and based on the clinical diagnosis；

  • People who have undergone conventional surgical treatment； ③ People who are conscious and able to communicate normally；

    ④ People who have provided informed consent and voluntarily participate in this study；

    ⑤ People aged ≥18 years.

Exclusion Criteria:

• Individuals with severe cognitive impairment;

  • Pathological fractures caused by tumors or other reasons; ③ People with other severe diseases, such as cancer, severe cardiopulmonary diseases, etc., who are unable to cooperate; ④ Individuals currently participating in other research projects.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Barthel Index	Barthel Index (BI) is widely used to quantify activities of daily living and is sensitive to short-term changes during hospitalization. A low BI at discharge limits the effectiveness of rehabilitation and is associated with poor prognosis. The lowest score on this scale is 0, and the highest score is 100.	At baseline, 3 days postoperatively, 7 days postoperatively and 30 days postoperatively data on Barthel Index.
EQ-5D-5L	EQ-5D is a health-related quality of life (HRQoL) questionnaire widely used in economic, clinical, and population health studies. The EQ-5D descriptive system comprises five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. It has two versions, a three-level EQ-5D (EQ-5D-3L) and a five-level EQ-5D (EQ-5D-5L). Each dimension of the EQ-5D-3L consists of 3 levels: no difficulty at all, some difficulty, and extreme difficulty.	At baseline, 3 days postoperatively, 7 days postoperatively and 30 days postoperatively data on EQ-5D-5L.
PNI	The PNI was derived using the formula: 10 × serum albumin (g/dL) + 0.005 × lymphocyte count (/mm3). Serum albumin < 4.0 g/dL = 1 point, ≥4.0 g/dL = 0 points and LMR < 4.44 = 1 point, ≥4.44 = 0 points. The total PNI varied from 0 to 4, higher values reflect a more favorable nutritional and inflammatory profile.	At baseline, 3 days postoperatively, 7 days postoperatively and 30 days postoperatively data on PNI.
EQ-VAS	Participants rated their current health on a 100-point EQ visual analog scale (EQ VAS), ranging from "worst imaginable health state" (0) to "best imaginable health state" (100).	At baseline, 3 days postoperatively, 7 days postoperatively and 30 days postoperatively data on EQ-VAS.

Collaborators and Investigators

• Sponsor: Shandong University

Study record dates

Study Major Dates

• Study Start (Actual): September 1, 2022
• Primary Completion (Actual): June 1, 2025
• Study Completion (Actual): July 1, 2025

Study Registration Dates

• First Submitted: May 22, 2026
• First Submitted That Met QC Criteria: June 12, 2026
• First Posted (Actual): June 15, 2026

Study Record Updates

• Last Update Posted (Actual): June 15, 2026
• Last Update Submitted That Met QC Criteria: June 12, 2026
• Last Verified: June 1, 2026

More Information

Terms related to this study

• Other Study ID Numbers: 2022-R-184

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No