Diagnostic Value of Strain Elastography in Characterization of Solid Breast Lesions.

June 10, 2026 updated by: Nada Yahia Abdellah, Sohag University

Breast lesions are a common concern in clinical practice, requiring accurate diagnostic tools for effective evaluation. Traditional imaging modalities, such as mammography and ultrasound, play critical roles in detecting and characterizing these lesions. However, the emergence of advanced techniques like strain elastography has significantly enhanced our ability to assess the mechanical properties of breast tissues, providing valuable insights beyond standard imaging. Strain elastography is a non-invasive ultrasound-based technique that evaluates tissue stiffness by measuring the degree of deformation in response to applied pressure. This technique capitalizes on the principle that malignant tissues are typically stiffer than benign ones, offering a potential method for differentiating between solid breast lesions. By assessing the elastic properties of breast tissues, strain elastography aids in improving diagnostic accuracy and reducing the need for unnecessary biopsies.

The diagnostic value of strain elastography lies in its ability to provide real-time feedback during ultrasound examinations. This immediacy allows clinicians to make informed decisions about further management based on the mechanical characteristics of the lesions. The integration of strain elastography into routine breast imaging protocols can enhance the specificity and sensitivity of lesion characterization, ultimately benefiting patient outcomes.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

30

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Sohag, Egypt
        • Sohag University Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Probability Sample

Study Population

Woman aged 18 years or older.

  • Having solid breast lesions identified through mammography or ultrasound and who are scheuduled for biopsy

Description

Inclusion Criteria:

  • Woman aged 18 years or older.
  • Having solid breast lesions identified through mammography or ultrasound and who are scheuduled for biopsy

Exclusion Criteria:

  • Patient with proor breast surgeries
  • patient who had alocalzied systemic diseases that prevents biopsy.
  • Inflammtory conditions

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Assessment of the mass harness by elastography
Time Frame: one year
assessmnet of the mass harness by elasography ration E2/E1
one year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2025

Primary Completion (Actual)

June 1, 2026

Study Completion (Actual)

June 1, 2026

Study Registration Dates

First Submitted

December 29, 2024

First Submitted That Met QC Criteria

June 10, 2026

First Posted (Actual)

June 16, 2026

Study Record Updates

Last Update Posted (Actual)

June 16, 2026

Last Update Submitted That Met QC Criteria

June 10, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Sog-Med--24-12-08MS

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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