In-Clinic Versus Tele-Rehabilitation in Women With Knee Osteoarthritis

Comparison Between In-clinic Versus Tele-rehabilitation on Knee Function, Muscle, Muscle Strength, and Pain in Women With Knee Osteoarthritis

• To compare the effectiveness of in clinic rehabilitation versus tele rehabilitation in improving knee function in women diagnosed with knee OA.
• To assess the impact of both rehabilitation approaches on improving strength.
• To evaluate the effects of in-clinic and tele-rehabilitation on pain reduction in women with knee osteoarthritis.

Study Overview

• Status: Completed
• Conditions: Total Knee Replacement
• Intervention / Treatment: Other: In-Clinic Rehabilitation; Other: Tele-Rehabilitaion

Detailed Description

Knee osteoarthritis (OA) is a chronic, progressive musculoskeletal disorder, which is marked by degeneration of articular cartilage, subchondral bone remodeling, inflammation of the synovium, and limitation of knee joint function. It is also among the primary causes of chronic pains, disability, and diminished physical functions in middle-aged and older adults across the world. Knee OA clinically appears with pain in the joints, stiffness, crepitus, reduced mobility, muscle weakness, and gradual impairment of activities of daily living, which eventually affects independence and quality of life.

• Study Type: Interventional
• Enrollment (Actual): 26
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Pakistan
  • KPK
    • Dargai, KPK, Pakistan, 23060
      • THQ Hospital Dargai

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Only female participant
• Age 40 to 60 years
• Radiographically confirmed OA (Grade II or III)
• Self-limitation in walking, climbing or ADLs
• Access to smartphone, tablet, or computer with internet

Exclusion Criteria:

• Advanced OA (G IV)
• Other joint disorder
• Recent surgeries
• Pregnancy
• Swelling and morning stiffness more than 30 min

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: In-Clinic Rehabilitation; Hot pack (for 15 minutes) Strengthening Exercises; Quadriceps Sets - 3 Sets of 10 Reps; Straight Leg Raise (SLR) - 3 Set of 10 Reps; Mini Squats (Wall-Supported) - 3 Sets of 10 Reps; Hamstring Curls (Standing or Prone) - Reps: 3 sets of 10 Reps - Add resistance band if tolerated; Seated Knee Extension (With or Without Weight) - 3 sets of 10 Reps -18 sessions for six weeks.	Other: In-Clinic Rehabilitation; Hot Pack & Strengthening Exercises
Experimental: Tele-Rehabilitation; Hot pack (for 15 minutes) Strengthening Exercises; Quadriceps Sets - 3 Sets of 10 Reps; Straight Leg Raise (SLR) - 3 Set of 10 Reps; Mini Squats (Wall-Supported) - 3 Sets of 10 Reps; Hamstring Curls (Standing or Prone) - Reps: 3 sets of 10 Reps - Add resistance band if tolerated; Seated Knee Extension (With or Without Weight) - 3 sets of 10 Reps -18 sessions for six weeks.	Other: Tele-Rehabilitaion; Hot Pack & Strengthening Exercises

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
WOMAC to assess knee function	The WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) is a widely used, self-administered 24-item questionnaire designed to evaluate pain, joint stiffness, and physical function in patients with knee or hip osteoarthritis. It measures these three dimensions to assess disease severity and treatment outcomes.	6 Weeks
MMT to assess knee muscle strength	Manual Muscle Testing (MMT) is a generally valid and reliable tool for assessing muscle strength in patients with neuromusculoskeletal dysfunction, demonstrating good consistency, particularly in clinical settings with trained examiners. It is widely used for grading muscle strength (0-5 scale), though it has limited sensitivity in detecting small strength changes and may have a ceiling effect for high-functioning individuals.	6 Weeks
VAS to assess pain	The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."	6 Weeks

Collaborators and Investigators

• Sponsor: Riphah International University
• Investigators: Principal Investigator: Ayesha Sadiq, MSPT (OMPT), Riphah International University

Study record dates

Study Major Dates

• Study Start (Actual): April 1, 2026
• Primary Completion (Actual): June 10, 2026
• Study Completion (Actual): June 10, 2026

Study Registration Dates

• First Submitted: June 13, 2026
• First Submitted That Met QC Criteria: June 13, 2026
• First Posted (Actual): June 17, 2026

Study Record Updates

• Last Update Posted (Actual): June 17, 2026
• Last Update Submitted That Met QC Criteria: June 13, 2026
• Last Verified: February 1, 2026

More Information

Terms related to this study

• Keywords: Pain; Muscle Strength; Knee Function
• Additional Relevant MeSH Terms: Neurologic Manifestations; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Pain
• Other Study ID Numbers: REC-01026 Hajra

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No