Comparison of Different Chest Compression Techniques in Infant Resuscitation

July 7, 2026 updated by: Gul Pamukcu Gunaydin, Ankara City Hospital Bilkent

Comparison of the Effectiveness of Different Chest Compression Techniques in Infant Resuscitation on a Manikin: A Prospective Randomized Simulation Study

In this prospective, single-center, randomized, self-controlled crossover manikin simulation study, participitants performed 2 minutes of single-rescuer CPR (30:2 compression-to-ventilation ratio) with each of the four techniques (the two-finger (2F), three-finger (3F), heel-of-one-hand (HOH), and two-thumb (2T) techniques) in a randomized order, with at least 10 minutes of rest between techniques. Chest compression depth, rate, release velocity, and the proportion of compressions within the target range were recorded using a feedback device. Provider fatigue and perceived difficulty (modified Borg scale) were assessed as secondary outcomes

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

116

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Resident physicians working in the Emergency Medicine Clinic of Ankara Bilkent City Hospital.
  • Voluntary agreement to participate in the study.

Exclusion Criteria:

  • Presence of a musculoskeletal disorder or disability that could interfere with CPR performance.
  • Unwillingness to participate.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Two-Finger (2F) Technique
Participants performed single-rescuer basic life support CPR on an infant manikin for 2 minutes using the two-finger technique with a 30:2 compression-to-ventilation ratio.
Procedure: Two-Finger (2F) Technique
Participants perform single-rescuer basic life support CPR on an infant manikin for 2 minutes using the two-finger chest compression technique with a 30:2 compression-to-ventilation ratio
Experimental: Three-Finger (3F) Technique
Participants performed single-rescuer basic life support CPR on an infant manikin for 2 minutes using the three-finger technique with a 30:2 compression-to-ventilation ratio.
Procedure: Three-Finger (3F) Technique
Participants perform single-rescuer basic life support CPR on an infant manikin for 2 minutes using the three-finger chest compression technique with a 30:2 compression-to-ventilation ratio.
Experimental: Heel-of-One-Hand (HOH) Technique
Participants performed single-rescuer basic life support CPR on an infant manikin for 2 minutes using the heel-of-one-hand technique with a 30:2 compression-to-ventilation ratio.
Procedure: Heel-of-One-Hand (HOH) Technique
Participants perform single-rescuer basic life support CPR on an infant manikin for 2 minutes using the heel-of-one-hand chest compression technique with a 30:2 compression-to-ventilation ratio.
Experimental: Two-Thumb (2T) Technique
Participants performed single-rescuer basic life support CPR on an infant manikin for 2 minutes using the two-thumb technique with a 30:2 compression-to-ventilation ratio.
Procedure: Two-Thumb (2T) Technique
Participants perform single-rescuer basic life support CPR on an infant manikin for 2 minutes using the two-thumb chest compression technique with a 30:2 compression-to-ventilation ratio.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Mean Chest Compression Depth
Time Frame: 2 minutes of CPR application
Measured in centimeters (cm) using a CPR feedback device.
2 minutes of CPR application
Mean Chest Compression Rate
Time Frame: 2 minutes of CPR application
Measured as compressions per minute
2 minutes of CPR application
Chest Compression Release Velocity
Time Frame: 2 minutes of CPR application
Measured in millimeters per second (mm/s)
2 minutes of CPR application
Compressions Within Target Range
Time Frame: 2 minutes of CPR application
Percentage of compressions performed within the target range.
2 minutes of CPR application

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Provider Fatigue
Time Frame: During the 2-minute CPR application
Defined and recorded as a 10% reduction in compression depth sustained over three consecutive compressions.
During the 2-minute CPR application
Perceived Difficulty
Time Frame: Assessed immediately after each 2-minute application.
Subjective level of difficulty assessed using the modified Borg scale, graded from 0 (no difficulty) to 10 (most severe difficulty).
Assessed immediately after each 2-minute application.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ankara City Hospital Bilkent

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2024

Primary Completion (Actual)

January 1, 2025

Study Completion (Actual)

January 1, 2025

Study Registration Dates

First Submitted

July 7, 2026

First Submitted That Met QC Criteria

July 7, 2026

First Posted (Actual)

July 13, 2026

Study Record Updates

Last Update Posted (Actual)

July 13, 2026

Last Update Submitted That Met QC Criteria

July 7, 2026

Last Verified

July 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • ASH2

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

De-identified individual participant data regarding CPR quality parameters (compression depth, rate, release velocity, etc.) underlying the results reported in this article will be shared.

IPD Sharing Time Frame

Data will become available immediately following the publication of the article and will be permanently accessible.

IPD Sharing Access Criteria

The data is openly accessible in the Mendeley Data repository.

IPD Sharing Supporting Information Type

  • SAP

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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