To Compare Predictive Power of End-tidal Carbon Dioxide Between Different Time Line During Resuscitation

To analyze a multi-center observational study database. to select adult non-traumatic in-hospital cardiac arrest. Review and recored end-tidal carbon dioxide in per minute. Arrange them in different time line. one is in resuscitation time. The other is the time line which the beginning time is the time of starting appearing stable end-tidal carbon dioxide wave.To compare predictive power of end-tidal carbon dioxide between different time line during resuscitation.

Study Overview

• Status: Unknown
• Conditions: Resuscitation
• Intervention / Treatment: Other: predictive power of end-tidal carbon dioxide

• Study Type: Observational
• Enrollment (Anticipated): 130

Contacts and Locations

Study Locations

• China
  • Beijing, China, 100730
    • Recruiting
    • Peking Union Medical College Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 100 years (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: N/A
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

CPR patient being treated in the emergency department

Description

Inclusion Criteria:

adult non-traumatic in-hospital cardiac arrest patients Exclusion Criteria:1) surrogate decision of Do-Not-Resuscitate (DNR) during CPR; 2) out-of-hospital cardiac arrest (OHCA) patient; 3) trauma as the main reason for medical treatment; 4) child or adolescent patients; 5) Petco2 value was not recorded effectively; 6) delay from initial CPR to starting to record Petco2 exceeded 30 min; and 7) screening by qualified experts. More than three experienced physicians thought that the patient's Petco2 value was too extreme to agree with his/her medical history, and the value was seen as an error and was excluded

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
resuscitation time line group; The ETCO2 will be arrange in resuscitation time line.	Other: predictive power of end-tidal carbon dioxide; end-tidal carbon dioxide predicts resuscitation outcomes
ETCO2 time line group; The ETCO2 will be arrange in time line which the beginning time is the time of starting to show stable ETCO2 wave.	Other: predictive power of end-tidal carbon dioxide; end-tidal carbon dioxide predicts resuscitation outcomes

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
predictive power of ETCO2 is week at the beginning of resuscitation	the later predictive power of ETCO2 is better during 30min resuscitation	1 week

Collaborators and Investigators

• Sponsor: Peking Union Medical College Hospital

Study record dates

Study Major Dates

• Study Start (Actual): November 10, 2017
• Primary Completion (Anticipated): November 15, 2017
• Study Completion (Anticipated): November 17, 2017

Study Registration Dates

• First Submitted: November 14, 2017
• First Submitted That Met QC Criteria: November 14, 2017
• First Posted (Actual): November 17, 2017

Study Record Updates

• Last Update Posted (Actual): November 17, 2017
• Last Update Submitted That Met QC Criteria: November 14, 2017
• Last Verified: November 1, 2017

More Information

Terms related to this study

• Other Study ID Numbers: 20171110PUMCHER

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No