Risk Factors, Etiology and Predictable Outcomes With Risk Stratification Scores in Acute Heart Failure Patients

August 23, 2026 updated by: Remoon Hana Henein Mansour, Assiut University

Clinical Characteristics, Etiology, Short-Term Outcomes, and Performance of Contemporary Risk Stratification Scores in Heart Failure Patients Presenting to Assiut University Heart Hospital.

Clinical Characteristics, Etiology, Short-Term Outcomes, and Performance of Contemporary Risk Stratification Scores in Acute Heart Failure Patients Presenting to Assiut University Heart Hospital.

Study Overview

Status

Not yet recruiting

Conditions

Acute Heart Failure (AHF)

Intervention / Treatment

Detailed Description

Primary Aim To characterize the demographic and clinical characteristics, etiological spectrum, precipitating factors, management, and short-term outcomes, including length of stay, ICU admission, organ failure, and 30-day rehospitalization, of patients presenting with acute heart failure at Assiut University Heart Hospital

.Secondary Aim To evaluate the prognostic performance of the HEARTRISK6 score by externally validating its ability to predict short-term adverse outcomes, including in-hospital mortality.

Study Type

Observational

Enrollment (Estimated)

350

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Name: Remoon hana Mansour
Phone Number: +201284555676
Email: Remon.18313629@med.aun.edu.eg

Study Locations

Egypt
- - Asyut, Egypt
    - AssiutU

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

Adult
Older Adult

Accepts Healthy Volunteers

Sampling Method

Non-Probability Sample

Study Population

Acute heart failure patients presenting to Emergency Department and Cardiology Department, Assiut University Hospitals, Egypt.

Description

Inclusion Criteria:

Age more than 18yrs
Clinical diagnosis of acute heart failure according to current ESC guideline criteria.

Exclusion Criteria:

Age below than 18
Refusal to participate.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Clinical Characteristics, Etiology, Short-Term Outcomes, and Performance of Contemporary Risk Stratification Scores in Acute Heart Failure Patients Presenting to Assiut University Heart Hospital. Time Frame: Follow up patients for 30 days	To externally validate the HEARTRISK6 score and evaluate its predictive performance for short-term adverse outcomes in patients with acute heart failure. History of moderate/severe valvular heart disease_Yes. 1 Heart rate >100 to ≤120 bpm. 2 >120 bpm. 3 Non-invasive ventilation (NIV)BiPAP/NIV within first hour 2 Creatinine >150 to ≤300 µmol/L 2 >300 µmol/L. 3 Troponin >3-5 × upper reference limit (URL) 1 >5 × URL. 2 Failed reassessment / 3-minute walk test ifFailed1 comp0 High score means worse	Follow up patients for 30 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Bohm M, Burri H, Butler J, Celutkiene J, Chioncel O, Cleland JGF, Coats AJS, Crespo-Leiro MG, Farmakis D, Gilard M, Heymans S, Hoes AW, Jaarsma T, Jankowska EA, Lainscak M, Lam CSP, Lyon AR, McMurray JJV, Mebazaa A, Mindham R, Muneretto C, Francesco Piepoli M, Price S, Rosano GMC, Ruschitzka F, Kathrine Skibelund A; ESC Scientific Document Group. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2021 Sep 21;42(36):3599-3726. doi: 10.1093/eurheartj/ehab368. No abstract available.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

August 1, 2026

Primary Completion (Estimated)

August 1, 2028

Study Completion (Estimated)

September 1, 2028

Study Registration Dates

First Submitted

August 8, 2026

First Submitted That Met QC Criteria

August 23, 2026

First Posted (Actual)

August 25, 2026

Study Record Updates

Last Update Posted (Actual)