R-GASTIM- Study of Gastric Cancer Operable (R-GASTIM)

August 24, 2026 updated by: Centre Leon Berard

R-GASTIM - Clinicobiological Cohort of Gastric Cancers

Clinicobiological cohort of gastric cancers operated in our institution.

Study Overview

Status

Recruiting

Conditions

Detailed Description

Study of microenvironment of gastric cancers using tumor and lymph nodes, collected as per standard of care. Analysis by RNASeq and HyperIon

Study Type

Observational

Enrollment (Estimated)

60

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Adult patients with non-metastatic resectable gastric and gastroesophageal junction adenocarcinoma, Stage IB to III treated with standard neoadjuvant chemotherapy, operated at Centre léon Bérard, with available tumor and lymph nodes samples

Description

Inclusion Criteria:

  • Adult patients with histologically proven non-metastatic resectable gastric and gastroesophageal junction adenocarcinoma, Stage IB to III be treated with standard neoadjuvant chemotherapy
  • Knwon response to neoadjuvant chemotherapy as per TRG criteria
  • Surgery of primary tumor done at Centre Léon Bérard. Availability of archival FFPE tumor block from initial diagnosis with at least 20% of tumor cells and collected lymp nodes

Exclusion Criteria:

  • Patient refusal to participate to this clinicobiological cohort

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Gene expression
Time Frame: surgery
Transcriptom of Surgery and lymp node specimen
surgery

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
HyperIon
Time Frame: surgery
Hyperion data on surgery and lymph nodes sample
surgery

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Centre Leon Berard

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 30, 2024

Primary Completion (Estimated)

September 30, 2027

Study Completion (Estimated)

September 30, 2027

Study Registration Dates

First Submitted

September 30, 2024

First Submitted That Met QC Criteria

August 24, 2026

First Posted (Actual)

August 26, 2026

Study Record Updates

Last Update Posted (Actual)

August 26, 2026

Last Update Submitted That Met QC Criteria

August 24, 2026

Last Verified

August 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • R201-004-117 (Registry Identifier: MR04 on site)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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