Pattern and Surgical Outcome of Papillary Thyroid Cancer at Sohag University Hospitals
Pattern and Surgical Outcome of Papillary Thyroid Cancer: A Case Series Study at Sohag University Hospitals
Study Overview
Status
Conditions
Detailed Description
Papillary thyroid carcinoma (PTC) is the most common histological subtype of thyroid cancer, representing about 80-85% of cases. This study is a case-series study with both retrospective (June 2023 - June 2026) and prospective (June 2026 - March 2027) components, conducted at the Department of General Surgery, Sohag University Hospitals.
All patients diagnosed with papillary thyroid carcinoma and managed at Sohag University Hospitals during the study period will be included. Data collection includes baseline demographic and clinical features, preoperative laboratory tests (thyroid function tests and serum calcium), neck ultrasonography findings (ACR TI-RADS category, nodule size, and lymph node assessment), fine-needle aspiration cytology (Bethesda System), surgical intervention types (hemithyroidectomy, total thyroidectomy, and neck dissection), final histopathological characteristics (tumor size, multifocality, lymphovascular invasion, extrathyroidal extension, and nodal status), and early postoperative complications (hypocalcemia, recurrent laryngeal nerve palsy, hematoma, seroma, and wound sepsis).
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Ahmed Aboulabed Resident Ahmed Aboulabed Ahmed Mousa, resident
- Phone Number: 01114522110
- Email: ahmed.aboulabed@yahoo.com
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- All patients diagnosed with papillary thyroid carcinoma and its variants managed at Sohag University Hospitals.
- Confirmation of diagnosis histopathologically.
- Availability of sufficient clinical, radiological, operative, and pathological data for analysis.
Exclusion Criteria:
- Patients diagnosed with other types of thyroid malignancy (e.g., follicular, medullary, or anaplastic carcinoma).
- Patients with a history of previous thyroid surgery before presentation to the study setting.
- Patients with incomplete essential medical records that prevent confirmation of diagnosis or extraction of main study variables.
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
|---|
|
patients with papillary thyroid carcinoma
All patients diagnosed with papillary thyroid carcinoma (and its variants) managed at Sohag University Hospitals during the study period (June 2023 to March 2027).
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Prevalence of Extrathyroidal Extension in Papillary Thyroid Carcinoma
Time Frame: 9 months
|
Percentage of participants with histologically confirmed extrathyroidal extension.
|
9 months
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Incidence of Early Postoperative Surgical Complications
Time Frame: 9 months
|
Percentage of participants experiencing early postoperative complications including hypocalcemia, recurrent laryngeal nerve palsy, hematoma, seroma, or wound sepsis.
|
9 months
|
|
Incidence of Multifocal Papillary Thyroid Carcinoma
Time Frame: 9 months
|
Percentage of participants found to have multifocal tumors on final histopathological examination.
|
9 months
|
|
Rate of Cervical Lymph Node Metastasis
Time Frame: 9 months
|
Percentage of participants with histopathologically confirmed cervical lymph node metastasis.
|
9 months
|
Collaborators and Investigators
Sponsor
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- Soh-Med-26-7-15MS
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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