Clinical Outcomes of Rectopexy for Rectal Prolapse

September 24, 2026 updated by: Lukas Marti

Rectopexy Outcome Study (RPE): Clinical Outcomes After Rectopexy for Rectal Prolapse

This study evaluates the clinical outcomes of patients who underwent rectopexy for rectal prolapse, ODS or FI. Rectopexy is a surgical procedure used to restore and fix the rectum in its normal position. The study examines treatment success, recurrence of rectal prolapse, functional outcomes, and postoperative complications. The aim is to better understand the long-term effectiveness and safety of rectopexy and to identify factors that may be associated with favorable or unfavorable outcomes.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

400

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Switzerland
    • Canton of St. Gallen
      • Sankt Gallen, Canton of St. Gallen, Switzerland, 9000
        • HOCH Health Ostschweiz Kantonsspital St. Gallen

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Adult patients who underwent rectopexy at the participating institution from 2011 onward because of external rectal prolapse, ODS or FI. The study population includes patients with available clinical and postoperative follow-up data allowing assessment of recurrence, postoperative complications, and functional outcomes after rectopexy.

Description

Inclusion Criteria:

Adult patients aged 18 years or older Diagnosis of external rectal prolapse, ODS or FI Are planned to undergo rectopexy for rectal prolapse at the participating institution Availability of postoperative follow-up data

Exclusion Criteria:

Age under 18 years No informed consent Insufficient clinical documentation to assess the study outcomes No postoperative follow-up available

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: COHORT
  • Time Perspectives: PROSPECTIVE

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Patients After Rectopexy for Rectal Prolapse

Patients who underwent rectopexy for rectal prolapse, ODS or Fecal Incontinence are included in this observational cohort. Clinical outcomes after surgery are assessed, including symptoms recurrence, recurrence of rectal prolapse, postoperative complications, and functional outcomes. No study-specific intervention is performed. Special subgroups as patients also operated for decent in the middle/anterior compartement might be accessed separately.
Procedure: anterior mesh rectopexy

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Recurrence of symptoms after Rectopexy (ODS, Prolapse, FI)
Time Frame: From surgery until the end of follow-up, up to 10 years

Proportion of patients with clinically diagnosed objective recurrence after rectopexy. Recurrence is defined as reappearance of symptoms (as FI, full-thickness external rectal prolapse) during follow-up.
From surgery until the end of follow-up, up to 10 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Lukas Marti

Collaborators

Cantonal Hospital of St. Gallen

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2011

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2035

Study Registration Dates

First Submitted

September 24, 2026

First Submitted That Met QC Criteria

September 24, 2026

First Posted (Actual)

September 30, 2026

Study Record Updates

Last Update Posted (Actual)

September 30, 2026

Last Update Submitted That Met QC Criteria

September 24, 2026

Last Verified

September 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2019-01331
  • 2019 (U.S. NIH Grant/Contract)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Individual participant data will not be shared because the study is based on clinical data collected within the participating institution and no external data-sharing plan has been established. Data will be handled in accordance with applicable ethical, legal, and data protection requirements. If a journal wants to check the data for a publication an anonymised sample of the patient data might be supplied.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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