Clinical Trials on "Hematologic Diseases" in United Kingdom

Total 147389 results

Lynn McMahon
Medical Research Council; CRUK Trials unit Glasgow

Unknown

Imatinib Mesylate With or Without Hydroxychloroquine in Treating Patients With Chronic Myeloid Leukemia

Leukemia

United Kingdom
Pfizer
pH Associates

Completed

A Study To Describe The Real World Use Of Bosutinib In The UK And Netherlands

Chronic Myeloid Leukaemia

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Copenhagen

Active, not recruiting

Bone Pain in Multiple Myeloma- a Translational Study (BPMM)

Multiple Myeloma

United Kingdom
University of Oxford

Completed

Intravenous Iron in Adults With Cystic Fibrosis

Iron-deficiency | Cystic Fibrosis

United Kingdom
Medical Research Council

Unknown

Combination Chemotherapy and Interferon Alfa With or Without Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United Kingdom
Riverside Haematology Group

Unknown

Combination Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia

Myelodysplastic Syndromes | Leukemia

United Kingdom
Cangene Corporation

Withdrawn

Study of Recombinant Factor IX Product, IB1001, in Previously Treated Subjects With Hemophilia B

Hemophilia B

United Kingdom, United States
Novo Nordisk A/S

Completed

Post-marketing Safety Surveillance of NovoSeven® in Patients With Haemophilia and Inhibitors by Means of the UK Haemophilia Database

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Dr Anthony Hobson
Anglia Ruskin University

Completed

GI Effects of Iron in Healthy Volunteers

Iron-deficiency | Microbial Colonization | Iron Deficiency Anemia | Iron Deficiency Anemia Treatment

United Kingdom
Medical College of Wisconsin

Terminated

Nivolumab and Tocilizumab for Relapsed Hematological Malignancy Post-allogeneic Transplant

Lymphoma | Myelodysplastic Syndromes | Acute Leukemia | Chronic Leukemia

United States
Novo Nordisk A/S

Completed

Investigation of the Pharmacokinetics of NNC172-2021, at Two Different Dose Levels, in Healthy Japanese Subjects

Healthy | Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Novo Nordisk A/S

Completed

A Single Dose Trial Investigating Safety and Local Tolerability of Ascending Doses of Long Acting Activated Recombinant Human Factor VII in Healthy Male Volunteers

Healthy | Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
University College, London

Active, not recruiting

Standard Chemotherapy With or Without Nelarabine or Rituximab in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia (UKALL14)

Leukemia | Mucositis | Oral Complications

United Kingdom
Prof Jamie Cavenagh
Novartis; Myeloma UK

Unknown

Velcade, Thalidomide, Dexamethasone and Panobinostat Treatment and Panobinostat Maintenance in Multiple Myeloma (MUKsix)

Multiple Myeloma

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London; Institute of Cancer Research, United Kingdom

Active, not recruiting

Machine Learning in Myeloma Response (MALIMAR)

Myeloma

United Kingdom
Cwm Taf University Health Board (NHS)
Cardiff Metropolitan University

Recruiting

Extracellular Vesicles and Dysregulated Coagulation in the Prediction of Stroke (PREDICT-EV)

Transient Ischemic Attack | Coagulation Disorder | Stroke, Ischemic

United Kingdom
BioMarin Pharmaceutical

Active, not recruiting

Gene Therapy Study in Severe Haemophilia A Patients (270-201)

Severe Haemophilia A

United Kingdom
University Hospitals of North Midlands NHS Trust
Staffordshire University; University Hospitals of North Midlands NHS Trust...

Completed

Covid-19 Vaccine Response in Immunocompromised Haematology Patients (COVAC-IC)

Covid19 | Immune Suppression | Haematological Disorders

United Kingdom
Novartis Pharmaceuticals

Terminated

A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
GlaxoSmithKline

Terminated

Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF)

Anaemia

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

Myeloma Novel Drug Discovery Ver 1.2 (DISCO)

Multiple Myeloma

United Kingdom
University of Oxford
British Heart Foundation; National Institute for Health Research, United Kingdom

Completed

Iron Status and Hypoxic Pulmonary Vascular Responses

Pulmonary Arterial Hypertension | Iron Deficiency | Lung Hypoxia

United Kingdom
Pfizer

Completed

Relative Bioavailability Of Two Formulations Of Moroctocog Alfa (AF-CC)

Hemophilia A

United Kingdom, Hungary, Bulgaria
Great Ormond Street Hospital for Children NHS Foundation...
King's College Hospital NHS Trust; University College London Hospitals; Guy's... and other collaborators

Recruiting

SMILES: Study of Montelukast in Sickle Cell Disease (SMILES)

Anemia, Sickle Cell | Sleep-Disordered Breathing

United Kingdom
Cell Medica Ltd
University College, London; Cell Therapy Catapult

Completed

WT1 TCR Gene Therapy for Leukaemia: A Phase I/II Safety and Toxicity Study

Acute Myeloid Leukaemia | Chronic Myeloid Leukaemia

United Kingdom
St. Bartholomew's Hospital

Unknown

Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease

Myelodysplastic Syndromes | Leukemia | Infection | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United Kingdom
Kiadis Pharma

Completed

Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

Canada, Belgium, Germany, Croatia, United Kingdom, Portugal
AstraZeneca
Parexel

Active, not recruiting

AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer

Advanced Haematological Malignancies

Spain, United States, Canada, Korea, Republic of, Poland, Australia, France, United Kingdom, Ireland
Shire

Completed

The Pharmacokinetics of Anagrelide in Elderly and Young Patients With Essential Thrombocythaemia (ET)

Essential Thrombocythaemia

Sweden, United Kingdom, Spain
The Christie NHS Foundation Trust

Not yet recruiting

Assessing the Relationship Between Hypoxia and the Immune Environment in Myeloma Patients (CHIME) (CHIME)

Myeloma

United Kingdom
Bio Products Laboratory

Completed

A Study to Investigate the Safety and Efficacy of Replenine®-VF in Haemophilia B Patients Undergoing Major Surgery.

Haemophilia B

United Kingdom
Genethon

Active, not recruiting

Long Term Safety Follow up of Haematopoietic Stem Cell Gene Therapy for the Wiskott Aldrich Syndrome (WASFUP)

Wiskott-Aldrich Syndrome

United Kingdom, France
Celgene

Active, not recruiting

A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers

Neoplasms

United States, France, Australia, Canada, Italy, Korea, Republic of, Spain, United Kingdom
Newcastle University
Bristol-Myers Squibb; Institute of Cancer Research, United Kingdom; Newcastle-upon-Tyne... and other collaborators

Completed

Comparison of Imatinib Versus Dasatinib in Patients With Newly-diagnosed Chronic Phase Chronic Myeloid Leukaemia (SPIRIT2)

Myeloid Leukemia, Chronic, Chronic Phase

United Kingdom
Joanne Turner

Recruiting

Utility of the Cardiac Electrical BiomarkerDisease (VECTRA)

Acute Chest Syndrome

United Kingdom
Becton, Dickinson and Company

Completed

Evaluation of the Plasma Cell Disorders Panel on the BD FACSLyric™ Flow Cytometer

Plasma Cell Disorder

Switzerland, Spain, United Kingdom, United States, Portugal
University College, London

Recruiting

Determining the Mechanisms of Loss of CAR T Cell Persistence (CARPERS)

Acute Lymphoblastic Leukemia, Pediatric | Acute Lymphoblastic Leukemia, in Relapse | Acute Lymphoblastic Leukemia, Adult | Acute Lymphoblastic Leukemia With Failed Remission | Acute Lymphoblastic Leukemia Not Having Achieved Remission

United Kingdom
Cleave Biosciences, Inc.

Terminated

A Phase 1 Study Evaluating CB-5083 in Subjects With Lymphoid Hematological Malignancies (CLC-102)

Lymphoid Hematological Malignancies | Relapsed and Refractory Multiple Myeloma

Canada, United States
University of Ulster
Northern Health & Social Care Trust (NHSCT); Solvotrin Therapeutics - Active...

Not yet recruiting

Adiposity and Iron Requirements in Pregnancy (ADIPREG)

Iron Deficiency Anemia of Pregnancy

United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Spain, United Kingdom
Queen Mary University of London
University College, London

Completed

Comprehensive Assessment of Nutrition and Dietary Intervention in Hypermobile Ehlers Danlos Syndrome (CANDI-hEDS2)

Irritable Bowel Syndrome | Functional Gastrointestinal Disorders | Hypermobile Ehlers-Danlos Syndrome

United Kingdom
Acerta Pharma BV
Acerta Pharma, LLC

Completed

An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma

Multiple Myeloma (MM)

United States, United Kingdom
Janssen Research & Development, LLC

Active, not recruiting

A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma (MajesTEC-1)

Hematological Malignancies

Canada, United States, France, Italy, United Kingdom, Germany, Belgium, Netherlands, Spain, Sweden, China
Imperial College London

Terminated

Iron Deficiency and Hereditary Haemorrhagic Telangiectasia

Hereditary Haemorrhagic Telangiectasia

United Kingdom
Imperial College London

Completed

Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs

Hereditary Hemorrhagic Telangiectasia | Pulmonary Arteriovenous Malformations

United Kingdom
Agios Pharmaceuticals, Inc.

Active, not recruiting

A Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AG-348 in Adult Participants With Non-transfusion-dependent Thalassemia

Thalassemia

United States, Canada, United Kingdom
CSL Behring

Completed

Observational Study of Prophylaxis and Treatment of Acute Perioperative Bleeding With Beriplex® P/N (Probe Study)

Coagulation Protein Disorders | Perioperative Care | Blood Loss, Surgical

United Kingdom
Bio Products Laboratory

Terminated

Optivate in People With Von Willebrand Disease Undergoing Surgery

Von Willebrand Disease

Israel, United Kingdom
Bio Products Laboratory

Terminated

A Study With OPTIVATE® in People With Von Willebrand Disease

Von Willebrand Disease

Israel, United Kingdom
Masonic Cancer Center, University of Minnesota

Terminated

Stem Cell Transplantation for Hematological Malignancies

AML | MDS | Leukemia, Lymphocytic, Acute

United States

Clinical Trials on "Hematologic Diseases" in United Kingdom

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