Clinical Trials on 5q- Syndrome

Total 33940 results

Johnson & Johnson Pharmaceutical Research & Development...
Centocor Ortho Biotech Services, L.L.C.

Terminated

A Study Evaluating Epoetin Alfa 40,000 IU (International Units) Every Week or 80,000 IU Every Week Compared to Placebo in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes at Risk for Transfusion

Myelodysplastic Syndromes | Anemia
M.D. Anderson Cancer Center
Genzyme, a Sanofi Company

Completed

2 Arm Study of Clofarabine IV in MDS Patients

Leukemia | Myelodysplastic Syndrome

United States
M.D. Anderson Cancer Center
The Vaccine Company

Terminated

PR1 Vaccination in Myelodysplastic Syndrome (MDS)

Leukemia | Myelodysplastic Syndrome

United States
Eli Lilly and Company
Daiichi Sankyo Co., Ltd.

Terminated

Study to Learn When Platelets Return to Normal After One Loading Dose of Anti-platelet Drugs in Patients With Symptoms of Acute Coronary Syndromes

Acute Coronary Syndromes

Germany
Kissei Pharmaceutical Co., Ltd.

Completed

A Study of KCT-0809 in Patients With Dry Eye Syndromes

Dry Eye Syndromes

Japan
Sirion Therapeutics, Inc.

Completed

Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-007)

Dry Eye Syndromes

United States
Hadassah Medical Organization

Withdrawn

Creation of Bone Marrow Microenvironment for Treatment of Myelodysplastic Syndrome (MDS) in Conjunction With Allogeneic Stem Cell Transplantation

Myelodysplastic Syndromes | Myelofibrosis

Israel
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Biological Therapy in Treating Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia

United States
Oxford University Hospitals NHS Trust

Unknown

Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants

Myelodysplastic Syndromes | Leukemia

United Kingdom
Hospices Civils de Lyon

Completed

Evaluation of the Efficacy and Safety of Recombinant Human Growth Hormone (rhGH) in the Treatment of Children With Short Bowel Syndrome

Short Bowel Syndrome

France
Glostrup University Hospital, Copenhagen

Unknown

Effect of the Enteric Hormone Glucagon-Like Peptide (GLP-2) on the Intestinal Blood Flow in Patients With Short Bowel Syndrome

Short Bowel Syndrome

Denmark
Chonnam National University Hospital

Completed

Comparison of Autologous Serum and Umbilical Cord Serum Eyedrops for Dry Eye Syndrome

Dry Eye Syndrome

Korea, Republic of
Laboratoires Thea

Completed

Efficacy of T1675 Versus Placebo in Patients With Bilateral Treated Moderate Dry Eye Syndrome

Dry Eye Syndromes
Huons Co., Ltd.

Not yet recruiting

To Evaluate the Efficacy and Safety of HUC3-053 in Patients With Dry Eye Syndrome

Dry Eye Syndromes
UCB BIOSCIENCES, Inc.

Recruiting

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome (ORCHID)

Dravet Syndrome

United States
Bristol-Myers Squibb

Recruiting

ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions (ELEMENT-MDS)

Myelodysplastic Syndromes

Canada, United States, China, Australia, France, Greece, Hungary, Germany, Italy, Czechia, Poland, Spain, Brazil, Colombia, India, Mexico, Argentina, Puerto Rico
University Hospital, Bordeaux

Not yet recruiting

Ferroptosis Study in SF3B1-mutant Myelodysplastic Syndromes (FerMDS) (FerMDS)

Myelodysplastic Syndromes | Ferroptosis

France
Cook Children's Health Care System
Encoded Therapeutics

Recruiting

GABA Biomarkers in Dravet Syndrome

Dravet Syndrome

United States
Hospices Civils de Lyon

Recruiting

Neurodevelopmental Impact of Epilepsy on Autonomic Function in Dravet Syndrome (AUTONOMIC)

Epilepsy | Dravet Syndrome

Belgium, France, Germany
Hanmi Pharmaceutical Company Limited

Recruiting

Phase 2 Study to Assess the Safety, PK, and PD in SBS-IF Subjects

Short Bowel Syndrome

Belgium, Korea, Republic of, United States, Germany, Denmark, France, Poland
University of Aberdeen
NHS Grampian; Softcell Medical Ltd

Not yet recruiting

Real-time Soft Tissue Assessment Using a Technologically Advanced pH Monitoring System (SoftpH)

Acute Compartment Syndrome

United Kingdom
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Three-dimensional Analysis of EMMPRIN on Conjunctival Epithelial Cells Surface in Severe Dry Eye Syndrome (ALTESSE) (ALTESSE)

Dry Eye Syndromes | Conjunctival Diseases

France
Agios Pharmaceuticals, Inc.

Active, not recruiting

A Study of AG-946 in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

Myelodysplastic Syndromes

Israel, United States, Korea, Republic of, Australia, France, Germany, Spain, United Kingdom, Czechia, Austria, Italy, Greece, Poland
Stoke Therapeutics, Inc

Enrolling by invitation

An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome

Dravet Syndrome

United States
University of Leipzig
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of Canakinumab for the Treatment of Anemia in LR-MDS Patients

Myelodysplastic Syndromes | Anemia

Germany
Alexandria University

Completed

Effect of an Educational Program on Health-related Outcomes of Patients With Dry Eye Syndrome

Dry Eye Syndrome

Egypt
University of Cincinnati
National Heart, Lung, and Blood Institute (NHLBI); Rare Diseases Clinical Research...

Completed

Assessment of Safety of Air Travel in Patients With Birt-Hogg-Dube Syndrome

Birt-Hogg-Dube Syndrome

United States
VectivBio AG

Active, not recruiting

Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome. (STARS extend)

Short Bowel Syndrome

United States, Belgium, United Kingdom, Korea, Republic of, Japan, Taiwan, Germany, France, Czechia, Hungary, Spain, Italy, Poland, Argentina, Denmark, Israel, Norway, Sweden
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Active, not recruiting

A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve (COMMANDS)

Myelodysplastic Syndromes

United States, Australia, Austria, Belgium, Canada, Czechia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Lithuania, Netherlands, Poland, Portugal, Russian Federation, Spain, Sweden, Switzerland, Taiwan, Turke... and more
Zealand Pharma

Completed

The Long-term Effect on Intestinal Absorption and Safety of Treatment With Glepaglutide in Patients With Short Bowel Syndrome (EASE SBS 4)

Short Bowel Syndrome

Denmark
University of Nebraska
Eli Lilly and Company

Terminated

Evaluate the Efficacy and Safety Growth Hormone, Glutamine and Diet in Patients With Short Bowel Syndrome (SBS)

Short Bowel Syndrome

United States
Shire
Takeda Development Center Americas, Inc.

Active, not recruiting

Registry for Participants With Short Bowel Syndrome

Short Bowel Syndrome

United States
Celgene

Completed

An Efficacy and Safety Study of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low or Intermediate Risk Myelodysplastic Syndromes (MDS) in Japanese Subjects Who Are Not Requiring Red Blood Cell Transfusion

Myelodysplastic Syndromes

Japan
Zealand Pharma

Completed

Efficacy And Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome (SBS) (EASE SBS 1)

Short Bowel Syndrome

United States, Denmark, Belgium, Germany, France, United Kingdom, Canada, Netherlands, Poland
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Neuronal Excitability of HCN1 Channel Mutations in Dravet Syndrome (EXCIDRAH)

Dravet Syndrome

France
Jazz Pharmaceuticals

Completed

Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1)

Epilepsy | Dravet Syndrome

France, United States, United Kingdom, Poland
Samjin Pharmaceutical Co., Ltd.

Completed

Clinical Study to Investigate the Efficacy and Safety of Orally Administered SA001 in Patients With Dry Eye Syndrome.

Dry Eye Syndrome

Korea, Republic of
Laboratoires Thea

Completed

Efficacy, Safety of T2769 in Dry Eye Disease

Dry Eye Syndrome

Tunisia
Mitotech, SA
ORA, Inc.

Completed

Vehicle-Controlled Study of SkQ1 as Treatment for Dry-eye Syndrome (VISTA-2)

Dry Eye Syndrome

United States
La Fundacion Favaloro para la Investigacion y la...
Fundación de Ciencias Exactas - UNLP

Enrolling by invitation

ImpRovE underSTanding of Short bOwel syndRome in Latin-amErica (RESTORE)

Short Bowel Syndrome

Argentina
Shire
Nycomed Germany GmbH

Completed

Open-Label Study of Teduglutide for Subjects With PN-Dependent Short Bowel Syndrome (SBS)

Short Bowel Syndrome

Spain, United States, Canada, France, Denmark, Poland, Germany, Italy, United Kingdom
Shire

Completed

Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome

Short Bowel Syndrome

United States, France, Germany, Canada, Netherlands, Poland, Denmark, Belgium, United Kingdom
Shire

Completed

Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome Who Completed Protocol CL0600-004 (NCT00081458)

Short Bowel Syndrome

United States, Denmark, France, Canada, Belgium, Netherlands, Poland, United Kingdom
Peking University Third Hospital

Unknown

CDSS of Traditional Chinese Medicine Intervention for Dry Eye Syndrome

Dry Eye Syndromes

China
Heart Care Foundation
AstraZeneca; Centro Servizi ANMCO S.r.l.

Completed

EYESHOT (EmploYEd Antithrombotic Therapies in Patients With Acute Coronary Syndromes HOspitalized in iTalian Coronary Care Units) (EYESHOT)

Acute Coronary Syndromes

Italy
9 Meters Biopharma, Inc.

Unknown

Proof of Concept Study in Patients With Short Bowel Syndrome

Short Bowel Syndrome

United States
Hospital Universitario de Canarias

Completed

Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome

Acute Coronary Syndromes

Spain
Redwood Pharma AB
Cross Research S.A.

Completed

Effects of RP101 in Post-menopausal Women With Dry Eye Syndrome

Dry Eye Syndromes

Austria, Germany, Hungary
INSYS Therapeutics Inc

Withdrawn

Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Participants With Inadequately Controlled Dravet Syndrome

Dravet Syndrome
Milton S. Hershey Medical Center
GlaxoSmithKline; The American Society of Cataract and Refractive Surgery Foundation

Completed

Oral Omega-3 Fatty Acids in the Treatment of Dry Eye Syndrome

Dry Eye Syndrome

United States

Clinical Trials on 5q- Syndrome

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Finland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations