Clinical Trials on Abnormalities, Drug-Induced in Netherlands

Total 1196 results

Erasmus Medical Center
Maasstad Hospital

Recruiting

FCV vs PCV in Moderate to Severe ARDS

Acute Respiratory Distress Syndrome | Ventilator Lung

Netherlands
University Hospital, Ghent
KU Leuven; Hasselt University; Maxima Medical Center

Recruiting

Speckle Tracking Echocardiography as a Tool for Early Diagnosis of Impaired Fetal Growth Twin Pregnancies (HEART)

Air Pollution | Placental Insufficiency | Fetal Growth Restriction | Cardiac Remodeling, Ventricular

Belgium, Netherlands
Leiden University Medical Center
Takeda; Netherlands Brain Foundation

Recruiting

Complement Inhibition: Attacking the Overshooting Inflammation @Fter Traumatic Brain Injury (CIAO@TBI)

Traumatic Brain Injury | Trauma, Head

Netherlands
Shire

Terminated

Extension of Study HGT-SAN-055 Evaluating Administration of rhHNS in Patients With Sanfilippo Syndrome Type A (MPS IIIA)

Sanfilippo Syndrome

Netherlands, United Kingdom
Editas Medicine, Inc.

Completed

Natural History Study of CEP290-Related Retinal Degeneration

Eye Diseases | Retinal Degeneration | Eye Diseases, Hereditary | Vision Disorders | Blindness | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

United States, Netherlands, France, Germany
Maastricht University Medical Center
AstraZeneca; Cystic Fibrosis Foundation

Completed

FLAME: Airway Inflammation Monitoring in Asthma and Cystic Fibrosis

Asthma | Cystic Fibrosis

Netherlands
Medtronic Bakken Research Center
Medtronic

Completed

Melody Transcatheter Pulmonary Valve (TPV) Post-Market Surveillance Study

Heart Valve Diseases

Canada, Denmark, Germany, Italy, Netherlands, Spain
Galapagos NV

Completed

Study of GLPG1837 in Subjects With Cystic Fibrosis (S1251N Mutation) (SAPHIRA2)

Cystic Fibrosis

Belgium, Netherlands
Maastricht University Medical Center

Unknown

Standardisation of Measurements in Exhaled Breath and Exhaled Breath Condensate.

Pneumonia | Asthma | Cystic Fibrosis | Chronic Lung Disease

Netherlands
Maastricht University Medical Center
Erasmus Medical Center; Jules Bordet Institute; Academisch Ziekenhuis Maastricht

Recruiting

Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI

Unspecified Adult Solid Tumor, Protocol Specific

Netherlands, Belgium
Academisch Medisch Centrum - Universiteit van Amsterdam...
The Stop ALD Foundation

Completed

The Effect of Bezafibrate on the Level of Very Long Chain Fatty Acids (VLCFA) in X-linked Adrenoleukodystrophy (X-ALD) (BEZA)

Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy

Netherlands
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
rEVO Biologics

Completed

A Phase I Safety, Pharmacokinetics and Pharmacodynamics Study of Recombinant Factor VIIa in Adult Patients With Hemophilia A or B (rhFVIIa)

Hemophilia

Netherlands, United States
aTyr Pharma, Inc.

Completed

Safety, Tolerability, Pharmacokinetics (PK), and Activity of ATYR1940 in Participants With Muscular Dystrophy - Study Extension

Facioscapulohumeral Muscular Dystrophy

United States, Italy, Netherlands
LivaNova

Active, not recruiting

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System. (CORE-VNS)

Epilepsy | Seizures | Drug Resistant Epilepsy

Australia, Italy, United States, Israel, United Kingdom, Canada, Brazil, Japan, Belgium, India, Austria, China, Netherlands, Poland, Portugal, Saudi Arabia
Swedish Orphan Biovitrum

Completed

Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

Netherlands, Poland
ModernaTX, Inc.

Recruiting

An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705

Methylmalonic Acidemia

United States, Canada, Netherlands, United Kingdom
UMC Utrecht
Turku University Hospital; University of Bologna; University of Roma La Sapienza and other collaborators

Recruiting

Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases (FURTHER)

Quality of Life | Pain | Neoplasm Metastasis | Bone Cancer | Bone Metastases | Tumor | Bone Neoplasm | Bone Lesion | Cancer Induced Bone Pain

Netherlands, Germany, Finland, Italy
University Childrens' Hospital (Zentrum für Kinderheilkunde...
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); University...

Recruiting

Connexin Genotypes in Cystic Fibrosis

Inflammation | Cystic Fibrosis

Germany, Netherlands
Ionis Pharmaceuticals, Inc.

Recruiting

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Pelizaeus-Merzbacher Disease

France, Netherlands
MyoKardia, Inc.

Completed

Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-491

Dilated Cardiomyopathy | Heart Failure With Reduced Ejection Fraction

United States, France, United Kingdom, Sweden, Germany, Netherlands, Poland
Stiefel, a GSK Company

Completed

Efficacy and Safety of Two Doses of Liarozole vs. Placebo for the Treatment of Lamellar Ichthyosis

Ichthyosis, Lamellar

Netherlands, Sweden, Germany, Belgium, Canada, Dominican Republic, France, Italy, Norway
Hospital Universitari Vall d'Hebron Research Institute

Active, not recruiting

GenoMed4ALL: Improving SCD Classification and Prognosis by AI (GenoMed4ALL)

Sickle Cell Disorders

Spain, Netherlands, France, Italy
Pharming Technologies B.V.

Completed

A Study of the Safety and Immunogenicity of Repeated rhC1INH Administration (OPERA)

Hereditary Angioedema | Genetic Disorders

Netherlands, Romania
Pharming Technologies B.V.

Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Hereditary Angioedema | Genetic Disorders | Angioneurotic Edema

Netherlands, Romania
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Flexor Tenotomy and Ulcer Recurrence

Hammer Toe Syndrome | Foot Ulcer, Diabetic

Netherlands
Novartis Pharmaceuticals

Completed

A Dose Escalation/Expansion Study of LDK378 in Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma Kinase

Tumors Characterized by Genetic Abnormalities of ALK

Australia, Belgium, Germany, Netherlands, Spain, Italy, Singapore, Korea, Republic of, United Kingdom, United States, Canada
OxThera

Completed

Phase 2/3 Oxabact Study

Primary Hyperoxaluria

United States, Germany, Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Performance and Patient Acceptance of a Commercially Available Beverage as Compared to an Oral Glucose Solution for Oral Glucose Tolerance Tests in Cystic Fibrosis (CF) Patients Who Are Screened for CF-related Diabetes.

Cystic Fibrosis | Cystic Fibrosis-related Diabetes

Netherlands
Ultragenyx Pharmaceutical Inc

Terminated

Clinical Survey Study to Assess Physical Function and the Incidence of Hypoglycemia in Participants With Glycogen Storage Disease Type III

Glycogen Storage Disease Type III

United States, Netherlands
Genethon

Recruiting

Gene Therapy for Severe Crigler Najjar Syndrome (CareCN)

Crigler-Najjar Syndrome

Italy, France, Netherlands
Amsterdam UMC, location VUmc
University Hospital, Essen; Institut Curie; Ligue contre le cancer, France

Completed

New Strategies to Detect Cancers in Carriers of Mutations in RB1 (NIRBTEST)

Retinoblastoma | Secondary Primary Malignancies After Retinoblastoma

Netherlands, France, Germany
Hoffmann-La Roche

Active, not recruiting

A Study To Investigate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of RO7248824 In Participants With Angelman Syndrome

Angelman Syndrome

United States, Spain, Netherlands, Italy
University Children's Hospital Tuebingen
European Union

Completed

Efficacy and Safety of Inhaled Budesonide in Very Preterm Infants at Risk for Bronchopulmonary Dysplasia (NEuroSIS)

Bronchopulmonary Dysplasia

Finland, Belgium, Czech Republic, France, Germany, Israel, Italy, Netherlands
CSL Behring

Active, not recruiting

Study of AAV5-hFIX in Severe or Moderately Severe Haemophilia B

Hemophilia B

Netherlands, Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...
Maastricht University Medical Center; Amsterdam UMC, location VUmc; St. Antonius... and other collaborators

Completed

REstricted Versus Liberal Positive End-Expiratory Pressure in Patients Without ARDS (RELAx)

Ventilator-free Days

Netherlands
T. van der Poll
ZonMw: The Netherlands Organisation for Health Research and Development; Prothya...

Terminated

C1-inhibitor in Allergic ASThma Patients (CAST)

Asthma

Netherlands
Bayer

Completed

Non-interventional Observation of Practical Implementation, Efficacy and Safety of Continuous Infusion With KOGENATE Bayer in Surgery (NO PEACKS)

Hemophilia A

Germany, Spain, Austria, Italy, Slovenia, Greece, Netherlands
ProQR Therapeutics

Recruiting

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene. (BRIGHTEN)

Eye Diseases | Neurologic Manifestations | Retinal Degeneration | Retinal Dystrophies | Sensation Disorders | Vision Disorders | Blindness | Leber Congenital Amaurosis | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

Belgium, Brazil, Canada, Germany, Italy, Netherlands, United Kingdom
BioMarin Pharmaceutical

Completed

Phase I/II Study of PRO044 in Duchenne Muscular Dystrophy (DMD)

Duchenne Muscular Dystrophy

Belgium, Netherlands, Italy, Sweden
Eline C. B. Eskes

Recruiting

Biomarkers Of Lung InVolvement In ASMD (BOLIVIA)

Asmd, Visceral Type

Netherlands
Maastricht University Medical Center
UMC Utrecht; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) and other collaborators

Enrolling by invitation

Noninvasive Electrocardiographic Imaging for Individuals at Risk for Apparently Idiopathic Ventricular Fibrillation. (VIGILANCE)

Cardiovascular Diseases | Ventricular Fibrillation | Heart Arrest | Cardiac Arrest | Ventricular Arrythmia | Polymorphic Ventricular Tachycardia | Sudden Cardiac Death | Cardiac Arrhythmia | Genetic Disease | Idiopathic Ventricular Fibrillation

Netherlands
Galapagos NV

Terminated

A Study to Evaluate the Effects of GLPG2737 in Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

Belgium, Netherlands, Italy, Spain, Czechia, Germany, Poland
Erasmus Medical Center
Stichting TAAI

Active, not recruiting

TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era (TERRIFIC-MILE)

Lung Diseases | Cystic Fibrosis | Infections, Bacterial | Congenital Disorders | Lung Inflammation | Lung Infection | Lung Disease; Cystic | Lung Disease; Cystic, Congenital | Inflammation Lungs | Exacerbation, Symptom

Netherlands
University Medical Center Groningen
Radboud University Medical Center; Maastricht University Medical Center; Erasmus... and other collaborators

Recruiting

Comparison of Standard Dose Alectinib to Alectinib in Adjusted Dose Based on Alectinib Bloodlevels (ADAPT ALEC)

Carcinoma, Non-Small-Cell Lung | Lung Cancer | Drug Monitoring | Anaplastic Lymphoma Kinase Gene Mutation | Anaplastic Lymphoma Kinase Gene Translocation

Netherlands, France
Hoffmann-La Roche

Completed

A Study to Investigate the Pharmacokinetics and Pharmacodynamics of RO7234292 (RG6042) in CSF and Plasma, and Safety and Tolerability Following Intrathecal Administration in Patients With Huntington's Disease

Huntingtons Disease

United Kingdom, Netherlands
Erasmus Medical Center
St. Antonius Hospital; Leiden University Medical Center; Amsterdam UMC

Completed

Personalized Targeted Immunomodulation in COVID-19 ARDS (COMODULATE)

COVID-19 Acute Respiratory Distress Syndrome

Netherlands
Prof. Dr. Marcus J. Schultz
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

PRactice of Ventilation and Adjunctive Therapies in COVID-19 Patients. (PRoVAcT-COVID)

COVID-19 Acute Respiratory Distress Syndrome

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Enrolling by invitation

The CHAMP-study: The CHemopreventive Effect of Lithium in Familial AdenoMatous Polyposis (Lithium in FAP)

Familial Adenomatous Polyposis

Netherlands
Vitaflo International, Ltd
University College London Hospitals; University Medical Center Groningen; University... and other collaborators

Completed

Glycosade v UCCS in the Dietary Management of Hepatic GSD (Glyde)

Glycogen Storage Disease

United States, United Kingdom, France, Netherlands

Clinical Trials on Abnormalities, Drug-Induced in Netherlands

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kazakhstan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations