Clinical Trials on Activating ALK Gene Mutation Negative
Total 4931 results
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Ascletis Pharmaceuticals Co., Ltd.RecruitingHIV Infections | HIV-1-infection | PD-L1 Gene MutationChina
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University of Wisconsin, MadisonRecruitingERα+ Breast Cancer | ESR1 Gene MutationUnited States
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UNICANCERCompletedKRAS Gene Mutation | Infiltrating Urothelial CarcinomaFrance
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TransThera Sciences (Nanjing), Inc.CompletedCholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Fusion | FGFR1 Alteration | FGFR3 AlterationUnited States
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Arog Pharmaceuticals, Inc.RecruitingRelapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating MutationsUnited States, Germany, Spain, Italy, France, Canada
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Henan Cancer HospitalRecruitingDiffuse Large B Cell Lymphoma | CD79A Gene Mutation | CD79B Gene MutationChina
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University of Colorado, DenverRecruitingNon-Small Cell Lung Cancer | ALK Gene Mutation | EGFR Gene Mutation | BRAF V600E | Non-Small Cell Carcinoma of Lung, TNM Stage 4 | ROSE Cluster 1United States
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Chonnam National University HospitalCompletedLung Neoplasms | EGFR Gene MutationKorea, Republic of
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingNSCLC Stage IV | ALK Gene Mutation | ALK Sensitizing MutationItaly
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Aarhus University HospitalRoche Pharma AGEnrolling by invitationLung Cancer | ALK Gene Mutation | Resistance, Disease | MutationDenmark
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University of UtahNational Cancer Institute (NCI)TerminatedObstructive Sleep Apnea Syndrome | Polycythemia Vera | Essential Thrombocythemia | CALR Gene Mutation | JAK2 Gene Mutation | MPL Gene MutationUnited States
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Jacobio Pharmaceuticals Co., Ltd.RecruitingSolid Tumors | ER+ Breast Cancer | ARID1A Gene Mutation | Triple Negative Breast Cancer, TNBC | Small Cell Lung Cancer, SCLCUnited States, China
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Institut für Klinische Krebsforschung IKF GmbH...Medizinische Hochschule Hannover, Germany, Prof. Dr. Arndt Vogel; MSD Sharp...RecruitingBiliary Tract Cancer | HER2 Gene MutationGermany
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Tianjin Medical University Cancer Institute and...RecruitingNon-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle DeregulationChina
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedMetastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | BRAF Gene MutationUnited States
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West Cancer CenterAmgen; University of Tennessee Health Science CenterUnknownMelanoma | BRAF Gene MutationUnited States
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Day One Biopharmaceuticals, Inc.RecruitingMelanoma | Colorectal Cancer | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Thyroid Cancer, Papillary | Pilocytic Astrocytoma | Bladder Urothelial Carcinoma | Non-Small Cell Adenocarcinoma | MEK Mutation | RAS Mutation | Pancreatic Acinar Carcinoma | RAF Mutation | CRAF Gene Amplification | RAF1 Gene Amplification and other conditionsUnited States, Canada, Korea, Republic of, Spain, Australia, Belgium, France
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OnKure, Inc.Active, not recruitingMelanoma | NRAS Gene Mutation | RAS MutationUnited States
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Royal Marsden NHS Foundation TrustPfizer; Breast Cancer NowActive, not recruitingGastric Cancer | Triple Negative Breast Cancer | Lobular Breast Carcinoma | CDH1 Gene MutationUnited Kingdom
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University Medical Center NijmegenActive, not recruitingOvarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene MutationNetherlands
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University of MalayaPfizer; Cancer Research Malaysia; Pantai Hospital Kuala Lumpur; Hospital Sultan...RecruitingTriple Negative Breast Cancer | HRD 100 Gene Expression HighMalaysia
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University of California, San FranciscoBeiGene USA, Inc.; Pacific Pediatric Neuro-Oncology ConsortiumRecruitingGlioblastoma | Malignant Glioma | Recurrent Glioblastoma | Recurrent WHO Grade III Glioma | WHO Grade III Glioma | IDH2 Gene Mutation | IDH1 Gene Mutation | Low Grade Glioma | Recurrent WHO Grade II Glioma | WHO Grade II GliomaUnited States
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Fudan UniversityPeking University First Hospital; Xiangya Hospital of Central South University and other collaboratorsUnknownGene Mutation | Epilepsy Idiopathic | Clinical Disease and/or SyndromeChina
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Universiti Sains MalaysiaCompletedOpioid Dependence | Methadone Toxicity | HERG Gene MutationMalaysia
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Hospices Civils de LyonRecruitingFamilial Mediterranean Fever | MEFV Gene MutationFrance
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University of ChicagoNovartisTerminatedHead and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Human Papillomavirus Infection | Recurrent Oropharyngeal Squamous Cell Carcinoma | FGFR Gene Amplification | FGFR1 Gene Amplification | FGFR2 Gene Amplification | FGFR2 Gene Mutation | FGFR3 Gene Mutation | Recurrent Nasopharynx...United States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingEGFR NP_005219.2:p.S492R | KRAS Gene Mutation | MAP2K1 Gene Mutation | Metastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7United States
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Arog Pharmaceuticals, Inc.CompletedPhase II Study of Crenolanib in Subjects With Relapsed/Refractory AML With FLT3 Activating MutationsRelapsed or Refractory Acute Myeloid Leukemia With FLT3 Activating MutationsUnited States
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National Taiwan University HospitalRecruitingCancer | Drug-Related Side Effects and Adverse Reactions | Cancer, Treatment-Related | EGFR Gene MutationTaiwan
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General Oncology, Inc.Myriad Genetics, Inc.RecruitingPancreatic Cancer | Pancreatic Ductal Adenocarcinoma | Pancreatic Cancer Stage IV | Breast Cancer Stage IV | BRCA1 Mutation | BRCA2 Mutation | Pancreatic Acinar Cell Carcinoma | Metastatic Pancreatic Cancer | Breast Cancer Metastatic | HER2-negative Breast Cancer | Metastatic Pancreatic Ductal Adenocarcinoma and other conditionsUnited States
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Myat Htut NyuntKangwon National UniversityCompletedDay-3 Positive of Parasitaemia | Prevalence of Drug Resistance Gene MutationMyanmar
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Sebastian BauerHannover Medical School; University Hospital Tuebingen; Universitätsmedizin Mannheim and other collaboratorsUnknownGIST, Malignant | KIT Gene Mutation | KIT Exon 13 MutationGermany
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Cancer Institute and Hospital, Chinese Academy...Not yet recruitingEarly-stage Triple-negative Breast Cancer With BRCA1/2 MutationsChina
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SUNHO（China）BioPharmaceutical CO., Ltd.RecruitingHER2 Gene MutationChina
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Shimaa KamalActive, not recruitingGene Mutation in Infantile Onset Diabetes MellitusEgypt
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Rhythm Pharmaceuticals, Inc.CompletedPro-opiomelanocortin (POMC), Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) and Leptin Receptor (LepR) Gene MutationsUnited States, Israel, Canada, Germany, Greece, Italy, Portugal
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Daiichi Sankyo, Inc.No longer availableAcute Myeloid Leukemia With Gene Mutations
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Jonsson Comprehensive Cancer CenterAstraZenecaActive, not recruitingGlioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | Supratentorial Glioblastoma | EGFR Gene Amplification | TP53 wt AlleleUnited States
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Blueprint Medicines CorporationActive, not recruitingNeoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditionsUnited States, Canada, Korea, Republic of, Japan, Taiwan
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Roswell Park Cancer InstituteAstraZenecaActive, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Serous AdenocarcinomaUnited States
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Guangxi Medical UniversityCompletedFull Gene Sequences of c-KIT、PDGFRA and DOG1 Are Analyzed With the Screening-sequencing Approach | Investigate the Characteristics and Variations Associated With the Different Gene Mutations of c-KIT、PDGFRA and DOG1 in GIST Patients
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University of WashingtonAbbVieNo longer availableTriple-Negative Breast Cancer | Metastatic Breast Cancer With BRCA 1 or BRCA 2 Genetic MutationUnited States
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RenJi HospitalPeking University First Hospital; Shanghai Zhongshan Hospital; First Affiliated... and other collaboratorsRecruitingKidney Cancer | Renal Cell Carcinoma | ALK Gene Mutation | MET Gene Mutation | HLRCC | Renal Tumor Histology | Cutaneous Leiomyoma | BAP1 Tumor Predisposition Syndrome | VHL Syndrome | Birt-Hogg-Dube Syndrome | Familial Renal Cancer | FLCN Gene Mutation | FH Gene Mutation | Cutaneous Leiomyomata With Uterine LeiomyomataChina
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Centro di Riferimento Oncologico - AvianoRecruitingBreast Neoplasms | Breast Diseases | Antineoplastic Agents | Aromatase Inhibitors | Neoplasms, Breast | Hormone Receptor Positive Breast Carcinoma | ESR1 Gene MutationItaly
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Taiho Oncology, Inc.TerminatedNon-Small Cell Lung Cancer | KRAS Gene Mutation | Advanced or Metastatic Solid Tumors Irrespective of Gene AlterationsUnited States
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Asan Medical CenterUnknownCancer | Lung Cancer Metastatic | MET Gene MutationKorea, Republic of
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Konkuk University Medical CenterFoundation Medicine; Roche DiagnosticsRecruitingAdenocarcinoma of Lung | EGFR Activating MutationKorea, Republic of
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Chonnam National University HospitalCompletedLung Neoplasms | EGFR Gene MutationsKorea, Republic of
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Massachusetts General HospitalGlaxoSmithKlineRecruitingRecurrent Glioma | Low-grade Glioma | Glioma, Malignant | IDH2 Gene Mutation | IDH1 MutationUnited States
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Sun Yat-sen UniversityRecruitingBrain Metastases | Radiotherapy | EGFR Activating MutationChina