Clinical Trials on Acute Renal Insufficiency in Czechia

Total 412 results

Fresenius Kabi
EastHORN Clinical Services in CEE; MLM Medical Labs GmbH; ALS Czech Republic,... and other collaborators

Completed

Short-term Metabolic Effects of Ketosteril® Supplemented Low Protein Diet in Pre-dialysis Chronic Kidney Disease (CKD) Patients (CKD)

Renal Insufficiency, Chronic

Czechia
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Charles University, Czech Republic
Ministry of Health, Czech Republic

Unknown

Metabolic Aspects of Citrate Anticoagulation in Renal Replacement Therapy (Citrate)

Critical Illness | Acute Renal Failure

Czech Republic
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease

Healthy Subjects | Severe Renal Impairment

Czechia
Hoffmann-La Roche

Completed

An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Patients With Chronic Kidney Disease Not On Dialysis

Kidney Disease, Chronic

Czechia
University Hospital Ostrava

Completed

Acute Kidney Injury in Severe Trauma

Acute Kidney Injury

Czechia
Daiichi Sankyo, Inc.
PRA Health Sciences

Completed

Pilot PK/PD Study of DS-1093a in Patients With Chronic Kidney Disease

Chronic Renal Disease | Renal Anemia

Czechia, Hungary
University Hospital Ostrava

Recruiting

Biomarkers of Kidney Function in Transplant Medicine

Acute Kidney Injury

Czechia
University Hospital Ostrava

Completed

Functional Effect of Treatment of Glottic Insufficiency With Calcium Hydroxyapatite

Glottic Insufficiency

Czechia
Institute for Clinical and Experimental Medicine

Completed

Molecular Markers of Acute Kidney Injury in Elderly Deceased Donors (MoliDon)

Kidney Transplantation | Acute Kidney Injury

Czechia
B.Braun Avitum AG
Winicker Norimed GmbH

Completed

Determination In-vivo KUF for Diacap Pro Hemodialyser

Renal Insufficiency,Chronic | Kidney Insufficiency | Kidney Disease, End-Stage | Kidney Failure,Chronic

Czech Republic
Novartis Pharmaceuticals

Completed

Pharmacokinetic Study of Buparlisib in Subjects With Renal Impairment.

Renal Impairment

Czechia, Germany, Romania, Bulgaria
Takeda

Completed

A Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics (PK) of a Single Intravenous (IV) TAK-954

Renal Impairment | Healthy Volunteers

Czechia, Hungary
University Hospital Ostrava
University Hospital Olomouc; University of Ostrava; Palacky University; Technical...

Completed

Specific miRNAs in Sepsis and Nephrotoxic Antibiotic Treatment

Sepsis | Septic Shock | Acute Kidney Injury

Czechia
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
Charles University, Czech Republic
Mount Sinai Hospital, New York; General University Hospital, Prague; Na Homolce...

Unknown

Renal Protection Using Sympathetic Denervation in Patients With Chronic Kidney Disease (KPS)

Arterial Hypertension | Chronic Renal Insufficiency

Czech Republic
Pieris Pharmaceuticals GmbH
FGK Clinical Research GmbH

Completed

Phase 2a Study to Evaluate PRS-080 in Anemic Chronic Kidney Disease Patients

Anemia of Chronic Kidney Disease

Czechia, Germany
University Hospital Ostrava

Completed

Development of Antibodies Against Transplant Kidney After Infection

Kidney Failure | Acute Infection

Czechia
Fresenius Medical Care Deutschland GmbH
Institut Dr. Schauerte GmbH (IDS)

Completed

Comparison of Clinical Performance and Hemocompatibility of Dialyzers Applied During Post-dilution Online Hemodiafiltration (eMPORAIII)

Renal Failure | End Stage Renal Disease

Germany, Czechia, Hungary
Bristol-Myers Squibb

Completed

A Study to Assess the Safety of Experimental Medication BMS986165 in Participants With Normal Kidney Function and Participants With Mild to End-Stage Kidney Disease.

Renal Impairment | Healthy Volunteer

United States, Czechia, Hungary, Poland
Value Outcomes Ltd.

Recruiting

Description of Treatment Patterns and Population Characteristics of Pre-dialysis CKD Patients in the Czech Republic

Chronic Kidney Diseases

Czechia
Novartis

Completed

Effect of Severe Renal Impairment on Pharmacokinetics and Metabolism of a Single Administration of Licarbazepine

Healthy

Czech Republic
GlaxoSmithKline

Completed

Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment

Pulmonary Disease, Chronic Obstructive

Czechia, Hungary
Bristol-Myers Squibb

Completed

A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function

Renal Failure | Congestive Heart Failure | Kidney Failure | Cardiac Failure | Myocardial Failure

Poland, Czechia
Fresenius Medical Care Deutschland GmbH

Completed

PD-Improved Dialysis Efficiency With Adapted APD (PD-IDEA)

Chronic Renal Failure

Spain, Sweden, Finland, Czechia, Denmark, Malaysia
Novo Nordisk A/S

Completed

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Various Degrees of Impaired Renal Function

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Hungary, Czechia
The Institute of Molecular and Translational Medicine...

Not yet recruiting

Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients

Critical Illness | Acute Respiratory Failure

Czechia
Taiho Oncology, Inc.

Completed

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

Advanced Solid Tumors

United States, Czechia, Serbia
University Hospital Ostrava

Completed

Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients

Septic Shock | Respiratory Insufficiency | Hypoxemia | Chronic Obstructive Pulmonary Disease Exacerbation | Lung Ventilator | Hyperhydration | Respiratory Distress Syndrome, Acute

Czechia
FORUM Pharmaceuticals Inc
PRA Health Sciences

Completed

EVP-6124 Renal Impairment Study

Renal Impairment

Czech Republic, Hungary
Sandoz

Terminated

Randomized, Controlled, Double-blind Multicenter Safety Study to Evaluate the Safety and Immunogenicity of Subcutaneous EPO HEXAL vs. ERYPO® in the Treatment of Anemia Associated With Chronic Renal Insufficiency in Predialysis Patients

Anemia | Chronic Renal Insufficiency

Austria, Slovakia, Russian Federation, Romania, Poland, Czechia, France, Germany, India, Bulgaria
Astellas Pharma Global Development, Inc.

Recruiting

A Study of Roxadustat to Treat Anemia in Children and Teenagers With Chronic Kidney Disease

Chronic Kidney Disease | Renal Anemia

Romania, Spain, Belgium, Germany, Norway, Slovakia, Denmark, Czechia
Astellas Pharma Inc

Completed

Renal Impairment Study With ASP1941

Type 2 Diabetes Mellitus

Hungary, Poland, Czechia, Slovakia
AM-Pharma
PPD

Completed

A Safety, Tolerability, Efficacy and QoL Study of Human recAP in the Treatment of Patients With SA-AKI (STOP-AKI)

Acute Kidney Injury

Spain, United States, France, United Kingdom, Austria, Ireland, Finland, Netherlands, Belgium, Czechia, Germany
AGC Biologics S.p.A.
Horizon 2020 - European Commission

Terminated

Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma

Acute Myeloid Leukemia | Multiple Myeloma

Italy, Czechia
Shire

Completed

A Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Investigate and Compare the Efficacy, Safety and Tolerability of Lanthanum Carbonate With Calcium Carbonate in Hyperphosphataemic Children and Adolescents With Chronic Kidney Disease on Dialysis

Chronic Kidney Disease | Hyperphosphatemia

Germany, Argentina, Chile, Czechia, Hungary, Poland, Romania, Russian Federation, Turkey
Institute for Clinical and Experimental Medicine

Active, not recruiting

Immunological Safety and Effectiveness of the First Booster Dose of mRNA Vaccines Against COVID-19 in Kidney Transplant Recipients.

COVID-19 | Kidney Diseases | Vaccine Adverse Reaction | Kidney Transplant; Complications | Rejection Acute Renal | Rejection Chronic Renal

Czechia
LEO Pharma

Completed

Innohep® in Elderly Patients With Impaired Renal Function Treated for Acute Deep Vein Thrombosis

Deep Vein Thrombosis

Bulgaria, Croatia, Czechia, France, Germany, Poland, Romania, Serbia, Spain
University Hospital Ostrava
České Budějovice Hospital

Recruiting

Emergent Microsurgical Intervention in Acute Stroke Patients After Mechanical Thrombectomy Failure Trial (EMIAS)

Acute Stroke | Surgical Procedure

Czechia
Novartis Pharmaceuticals

Recruiting

A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.

Acute Kidney Injury Following Cardiac Surgery

France, Taiwan, Belgium, Germany, Argentina, Spain, Czechia, Hungary, Singapore, Lithuania, Estonia, Brazil
Fresenius Medical Care Deutschland GmbH

Completed

Initiative for Patient Outcomes in Dialysis - Peritoneal Dialysis (PD) (IPOD-PD Study) (IPOD-PD)

Chronic Renal Failure

Spain, Korea, Republic of, Denmark, Finland, Netherlands, Belgium, United Kingdom, Turkey, France, Italy, Estonia, Sweden, Czech Republic, Austria, Bosnia and Herzegovina, Brazil, Croatia, Cuba, Germany, Greece, India, Israel, Latvia, Lithuani... and more
Oncopeptides AB

Terminated

PK of Melphalan During Treatment With Melflufen and Dexamethasone in Patients With RRMM and Impaired Renal Function (BRIDGE)

Multiple Myeloma | Renal Impairment

Greece, Czechia, Poland
Astellas Pharma Europe B.V.
FibroGen

Completed

Roxadustat in the Treatment of Anemia in End Stage Renal Disease (ESRD) Patients on Stable Dialysis (Pyrenees)

Anemia | End Stage Renal Disease (ESRD)

Bulgaria, Croatia, Czechia, Germany, Hungary, Poland, Russian Federation, Serbia, Spain, United Kingdom, Belgium, France, Georgia, Italy, Portugal, Romania, Slovakia
Vifor Pharma

Completed

Study of Phosphate Levels in Patients With Chronic Kidney Disease (PA21)

Chronic Kidney Disease

United States, Switzerland, Romania, Croatia, Bulgaria, Germany, Czech Republic, Poland, Russian Federation
Guard Therapeutics AB

Terminated

Efficacy and Safety of RMC-035 in Subjects at High Risk for Acute Kidney Injury Following Open-Chest Cardiac Surgery (AKITA)

Acute Kidney Injury

Spain, United States, Germany, Canada, Czechia
Boehringer Ingelheim

Completed

Treatment of Patients Undergoing Primary Unilateral Elective Total Knee or Hip Replacement With Dabigatran Etexilate

Arthroplasty, Replacement | Prevention of Venous Thromboembolism | Moderate Renal Impairment (CrCl 30-50 mL/Min)

Austria, Canada, Czechia, Finland, Netherlands, Sweden
TC Biopharm

Completed

Ex-vivo Expanded γδ T-lymphocytes (OmnImmune®) in Patients With Acute Myeloid Leukaemia (AML)

Acute Myeloid Leukemia

Czechia
Affymax
Takeda

Completed

Safety and Efficacy of Peginesatide for the Treatment of Anemia in Participants With Chronic Renal Failure Not on Dialysis (PEARL 2)

Anemia | Chronic Kidney Disease | Chronic Renal Failure

United States, Bulgaria, United Kingdom, Czech Republic, Germany, Hungary, Italy, Poland, Puerto Rico, Romania
Hoffmann-La Roche

Completed

A Study to Assess All-Cause Mortality and Cardiovascular Morbidity in Participants With Chronic Kidney Disease (CKD) on Dialysis and Those Not on Renal Replacement Therapy Receiving Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) or Reference Erythropoietin Stimulating Agents (ESAs)

Chronic Renal Anemia

Belgium, Brazil, United Kingdom, Serbia, Spain, Germany, Korea, Republic of, Turkey, Lithuania, Italy, Czechia, Argentina, Australia, Croatia, France, Greece, Israel, Malaysia, Mexico, Panama, Philippines, Poland, Russian Federation, ... and more
Novartis Pharmaceuticals

Completed

Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM) (TRANSFORM)

Hemodialysis | Renal Replacement Therapy | End Stage Renal Disease (ESRD) | Renal Transplantation | Chronic Kidney Disease (CKD)

Germany, United States, Belgium, Italy, Spain, Croatia, Taiwan, Australia, Austria, Greece, Korea, Republic of, Lebanon, Czechia, Israel, Netherlands, Slovenia, Switzerland, Thailand, Norway, Turkey, Sweden, Argentina, Brazil, Japan, Se... and more

Clinical Trials on Acute Renal Insufficiency in Czechia

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