Clinical Trials on Acute Hyperkalemia

Total 15673 results

AstraZeneca

Active, not recruiting

A Multicenter, Prospective, Non-interventional Cohort Study to Evaluate the Safety and Treatment Pattern of Sodium Zirconium Cyclosilicate for Hyperkalaemia Management in Real World Practice in China (ACTUALIZE)

Hyperkalaemia

China
AstraZeneca

Recruiting

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia (PEDZ-K)

Hyperkalaemia

China, Germany, United States, Ukraine, Spain, Japan, United Kingdom, Canada, Poland, Romania, Russian Federation, Brazil
AstraZeneca

Terminated

Study of SZC and Enhanced Nutrition Advice Compared to SoC in Dialysis Patients With Hyperkalaemia (GRAZE)

Hyperkalaemia

United States
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
National Defense Medical Center, Taiwan

Completed

Artificial Intelligence Identified Dyskalemia Using Electrocardiogram (AIDE)

Hypokalemia | Hyperkalemia

Taiwan
Medical University of Vienna

Completed

Perioperative Fluid Management in Patients Receiving Cadaveric Renal Transplants

Metabolic Acidosis | Hyperkalaemia Requiring Postoperative Dialysis

Austria
University of California, Irvine

Recruiting

Comparison of Potassium Binders in the ER (KBindER)

Acute Hyperkalemia | Oral Potassium Binders

United States
King Faisal Specialist Hospital & Research Center

Completed

Rate of Termination of Premixed Parenteral Nutrition (PN) in Surgical Patients Secondary to High Serum Electrolytes

Hyperphosphatemia | Hyperkalemia | Hypercalcemia | Hypermagnesemia

Saudi Arabia
AstraZeneca

Active, not recruiting

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone (REALIZE-K)

Heart Failure With Reduced Ejection Fraction | Hyperkalaemia

United States, Spain, Canada, Brazil, Hungary, Czechia, Ukraine, Poland, United Kingdom
AstraZeneca
Fudan University

Completed

Description of the Clinical Outcomes of Hospitalized Patients With Heart Failure With Different Serum Potassium Levels (SPLENDID)

Heart Failure | Hypokalemia | Hyperkalemia

China
St George's, University of London

Recruiting

Lokelma for RAAS Maximisation in CKD & Heart Failure. (LIFT)

Chronic Kidney Diseases | Heart Failure With Reduced Ejection Fraction | Hyperkalemia | ACE Inhibitor Induced Hyperkalaemia | Mineralocorticoid Resistant Hyperkalemia

United Kingdom
Aga Khan University

Unknown

Comparison of Enteral Versus Intravenous Potassium Supplementation (EIPS)

Acute Hypokalemia

Pakistan
AstraZeneca

Completed

Safety of Oral Resin for Treatment of Hyperkalemia in Chinese Patients With Renal Insufficiency (SCRUTINIZE)

Hyperkalaemia

China
Centre Integre Universitaire de Sante et Services...
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Evidence for Potassium Restriction in Hemodialysis (EvoKe-HD)

Hyperkalemia, Diminished Renal Excretion

Canada
Portsmouth Hospitals NHS Trust
Vifor Pharma

Recruiting

Hyperkalaemia and Its Impact on Therapy With RAASi (REVIEW)

Heart Failure With Reduced Ejection Fraction | Left Ventricular Systolic Dysfunction | Hyperkalaemia

United Kingdom
AstraZeneca

Completed

Retrospective Study to Describe Prevalence of Hyperkalemia in Russian Population Based on Large Laboratory Network (HEKATE)

Hyperkalemia Elevated Plasma K+ Cardiovascular Disease (CVD)

Russian Federation
Erasmus Medical Center
University Medical Center Groningen; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Potassium Supplementation in CKD (K+ in CKD)

Hypertension | Renal Insufficiency, Chronic | Hyperkalemia | Potassium Depletion

Netherlands
Rigshospitalet, Denmark
Herlev and Gentofte Hospital

Recruiting

Targeted Potassium Levels for Prevention of ICD Therapy

Atrial Fibrillation | Ventricular Tachycardia | Implantable Defibrillator User | Hypokalemia | Ventricular Arrhythmias and Cardiac Arrest | Hyperkalemia

Denmark
Vifor Pharma, Inc.

Recruiting

Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age

Hyperkalemia

United States, Israel
University of Aleppo

Recruiting

Levalbuterol Compared to Albuterol Regarding Cardiac Side Effects and Potassium Lowering Effects.

Hyperkalemia

Syrian Arab Republic
Portsmouth Hospitals NHS Trust
Vifor Pharma

Recruiting

IMpact of hyPeRkalaemia on thErapy With Renin angiotenSin aldoSterone System Inhibitors (IMPRESS)

Hyperkalemia

United Kingdom
Waterstone Pharmaceutical (Wuhan) Co., LTD.

Completed

The Safety and Tolerability of WS016 in Healthy Chinese Volunteers

Hyperkalemia

China
AstraZeneca

Completed

A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8 (ENERGIZE)

Hyperkalemia

United States, Russian Federation, Italy, Denmark
ZS Pharma, Inc.

Completed

Safety & Efficacy of Zirconium Silicate in Mild to Moderate Hyperkalemia

Hyperkalemia

United States, Australia
The University of Texas Health Science Center,...
Memorial Hermann Hospital

Completed

Relationship Between Potassium Level in Venous Blood Samples Drawn and Heel Sticks In Infants and Newborns (PS)

Hyperkalemia

United States
Haseki Training and Research Hospital

Completed

How Much Reliable iv Calcium for the Treatment of Hyperkalemia?

Acute Renal Failure | Chronic Renal Failure

Turkey
AstraZeneca

Recruiting

Continuing Sodium Zirconium Cyclosilicate (SZC) After Discharge Study (CONTINUITY)

Chronic Kidney Disease | Hyperkalaemia

Spain, United Kingdom, Belgium, Italy, Netherlands, France, Germany
Waterstone Pharmaceutical (Wuhan) Co., LTD.

Recruiting

A Study to Evaluate the Safety and Efficacy of WS016 in Patients With Hyperkalemia.

Hyperkalemia

China
Alexandria University

Recruiting

SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients

Hyperkalemia

Egypt
Zeria Pharmaceutical

Completed

A Comparative Study of ZG-801 and Placebo in Patients With Hyperkalemia

Hyperkalemia

Japan
AstraZeneca

Completed

Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects (DIALIZE China)

Hyperkalemia

China
AstraZeneca

Completed

A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia. (HARMONIZE Asia)

Hyperkalemia

China
Ardelyx

Completed

A Study Evaluating the Safety and Efficacy of RDX013 for the Treatment of Hyperkalemia (Redukx)

Hyperkalemia

United States
Relypsa, Inc.

Terminated

An Open-Label, Multiple Dose Study to Evaluate the Pharmacology, Safety, and Tolerability of Patiromer in Participants on Hemodialysis

Hyperkalemia

United States
Medical University of Graz
NGFI Next Generation Fluorescence Imaging GmbH

Completed

Clinical Potassium Pilot Study

Hyperkalemia

Austria
AstraZeneca

Completed

A Study to Test Whether ZS (Sodium Zirconium Cyclosilicate) Can Reduce the Incidence of Increased Blood Potassium Levels Among Dialized Patients. (DIALIZE)

Hyperkalemia

United States, United Kingdom, Russian Federation, Japan
Ardelyx

Terminated

A Study Evaluating the Onset-of-Action, Safety, and Efficacy of RDX227675 for the Treatment of Hyperkalemia

Hyperkalemia

United States
AstraZeneca

Completed

ZS Ph2/3 Dose-response Study in Japan

Hyperkalemia

Japan
ZS Pharma, Inc.

Completed

Safety & Efficacy of Zirconium Silicate Dosed for 28 Days in Hyperkalemia.

Hyperkalemia

United States, South Africa, Australia
ZS Pharma, Inc.

Completed

Open-label Safety and Efficacy of Sodium Zirconium Cyclosilicate for up to 12 Months

Hyperkalemia

United States, Germany, Australia, Netherlands, South Africa, Romania, United Kingdom
ZS Pharma, Inc.

Completed

POtassium and Cardiac Rhythm Trends in MaintENance HemoDialysis: A Multicenter, Prospective, Observational Study (PORTEND)

Hyperkalemia

United States
Zeria Pharmaceutical

Completed

Exploratory Study of ZG-801 for the Treatment of Hyperkalemia

Hyperkalemia

Japan
AstraZeneca

Completed

A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia (HARMONIZE GL)

Hyperkalemia

Korea, Republic of, Taiwan, Russian Federation, Japan
AstraZeneca

Completed

Open-label Safety of Sodium Zirconium Cyclosilicate for up to 12 Months in Japanese Subjects With Hyperkalemia

Hyperkalemia

Japan
ZS Pharma, Inc.

Completed

Open-label Safety & Efficacy of ZS (Sodium Zirconium Cyclosilicate)10g qd to Extend Study ZS-004 in Hyperkalemia.

Hyperkalemia

United States, South Africa, Australia
AstraZeneca

Completed

A Safety and Pharmacodynamic Study of Healthy Chinese Subjects Administered Sodium Zirconium Cyclosilicate (ZS)

Hyperkalemia

Hong Kong
University of Zurich

Completed

Clinical Decision Support System for Quality Assurance in Potassium-Increasing Drug-Drug-Interactions

Hyperkalemia

Switzerland
ZS Pharma, Inc.

Terminated

Safety and Efficacy of Sodium Polystyrene Sulfonate in Hyperkalemia

Hyperkalemia

United States
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Nebulized Salbutamol Facilitate Management of Hyperkalemia Postreperfusion During Liver Transplantation

Liver Transplantation
NephroNet, Inc.
AstraZeneca

Completed

A Prospective, Randomized, Open-Label, Cross-Over Study of Lokelma to Control Interdialytic Hyperkalemia (ADAPT)

Hyperkalemia

United States

Clinical Trials on Acute Hyperkalemia

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