Clinical Trials on Acute Illness

Total 17909 results

Heidelberg University
Charite University, Berlin, Germany; University of Kiel; Ludwig-Maximilians -... and other collaborators

Unknown

German Centre for Cardiovascular Research Cardiomyopathy Register (TORCH)

Amyloidosis | Acute Myocarditis | Dilated Cardiomyopathies | Hypertrophic Cardiomyopathies | Left Ventricular Myocardial Noncompaction Cardiomyopathy | Arrhythmogenic Right Ventricular Cardiomyopathies

Germany
University of Rostock

Completed

Fabry and Stroke Epidemiological Protocol (FASEP): Risk Factors In Ischemic Stroke Patients With Fabry Disease (FASEP)

Stroke, Acute | Cerebrovascular Accident | Cerebral Stroke

Germany, Poland
University Hospital, Montpellier

Recruiting

Use of Extracorporeal CO2 Removal in Case of Moderate to Severe ARDS to Apply an Ultraprotective Mechanical Ventilation Strategy (ECCO2R)

Acue Respiratory Distress Syndrome

France
University of North Carolina, Chapel Hill

Recruiting

Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Stroke | Brain Ischemia | Brain Injuries, Traumatic | Heart Arrest | Intracranial Hemorrhages | Brain Hypoxia | Coma | Hypoxia-Ischemia, Brain | Persistent Vegetative State | Brain Injuries, Acute

United States
Vanderbilt University Medical Center
American Heart Association

Recruiting

Long COVID Immune Profiling

Long COVID | Autonomic Dysfunction | POTS - Postural Orthostatic Tachycardia Syndrome

United States
First Affiliated Hospital Xi'an Jiaotong University
General Hospital of Ningxia Medical University; Second Affiliated Hospital... and other collaborators

Not yet recruiting

Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics (PROSPECT)

Coronary Artery Disease | Hypertension | Arrhythmias, Cardiac | Heart Valve Diseases | Brain Neoplasms | Myocarditis | Cardiomyopathies | Aortic Dissection | Structural Heart Disease | Heart Neoplasms | Ischemic Cerebrovascular Disease | Hemorrhagic Cerebrovascular Disease

China
University of British Columbia
Vancouver Coastal Health Research Institute; Genome British Columbia

Recruiting

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia (ACCURATE)

Acute Coronary Syndrome | Familial Hypercholesterolemia | STEMI | NSTEMI - Non-ST Segment Elevation MI | Familial Hypercholesterolemia - Heterozygous | Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B | Familial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation and other conditions

Canada
Balt Extrusion

Recruiting

Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform

Peripheral Vascular Diseases | Acute Ischemic Stroke | Intracranial Aneurysm | AVM | AVM - Cerebral Arteriovenous Malformation | Brain Arterial Disease

France, Spain
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATL)

Acute Adult T-Cell Leukemia/Lymphoma | Adult T-Cell Leukemia/Lymphoma | Chronic Adult T-Cell Leukemia/Lymphoma | HTLV-1 Infection

United States
Leidos Life Sciences
United States Department of Defense

Withdrawn

Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) in Hospitalized Patients With COVID-19 (Addendum 1)

COVID-19 | Covid19 | Coronavirus Disease 2019 | SARS-CoV-2 Infection | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Pandemic | COVID-19 Virus Infection | COVID-19 Virus Disease | 2019 Novel Coronavirus Disease | 2019 Novel Coronavirus Infection | 2019-nCoV Disease | 2019-nCoV Infection
Henry Ford Health System

Terminated

Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients (STOP-NT)

Bacteremia | Endocarditis | Acute Bacterial Skin and Skin Structure Infections | Health Care Associated Pneumonia | Osteomyelitis/Septic Arthritis

United States
OSF Healthcare System

Terminated

Observational Study of COVID-19 Treatment Efficacy

COVID-19 | Coronavirus Infection | COVID | Corona Virus Infection | Coronavirus | Sars-CoV2 | SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere | Coronavirus Disease | Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere | Coronavirus as the Cause of Diseases Classified...

United States
Leidos Life Sciences
United States Department of Defense

Terminated

Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients (Addendum 2)

COVID-19 | Covid19 | Coronavirus Disease 2019 | SARS-CoV2 Infection | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Pandemic | COVID-19 Virus Infection | COVID-19 Virus Disease | 2019 Novel Coronavirus Disease | 2019 Novel Coronavirus Infection | 2019-nCoV Disease | 2019-nCoV Infection

United States
Agence Sanitaire et Sociale de Nouvelle Calédonie
Institut Pasteur; World Health Organization; Pacific Community; Institut de la...

Suspended

Baromètre Santé Adulte 2021-2022

Diabetes | Renal Failure | Chronic Disease | Hypercholesterolemia | Malaria | SARS-CoV Infection | Dengue Fever | Chikungunya | Zika | Ross River

New Caledonia
Bin Li

Unknown

Efficacy Study of Gene Therapy for The Treatment of Acute LHON Onset Within Three Months (LHON)

Acute LHON | Onset Within Three Months | Onset Between 3 to 6 Months | Onset Between 6 to 12 Months | Onset Between 12 to 24 Months | Onset Between 24 to 60 Months | Onset Over 60 Months

China
Chinese PLA General Hospital

Completed

Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Brain Tumor | Liver Cancer | Ovarian Tumor | Acute Myeloid and Lymphoid Leukemias

China
Masonic Cancer Center, University of Minnesota

Terminated

Post Transplant Donor Lymphocyte Infusion

Multiple Myeloma | AML | Myelodysplastic Syndrome | Leukemia, Lymphocytic, Acute | Lymphomas | Leukemia, Myeloid, Chronic | Leukemia, Lymphocytic, Chronic

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI); Blood and Marrow Transplant Clinical Trials...

Completed

Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Acute Leukemia | Chronic Myelogenous Leukemia | Myelodysplasia | Small Lymphocytic Lymphoma

United States
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Anhui Provincial Hospital; The First People's Hospital of Hefei; Hefei Binhu...

Unknown

CAR-T Cell Immunotherapy in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma

Follicular Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | Diffuse Large Cell Lymphoma | B-cell Prolymphocytic Leukemia

China
AstraZeneca
PHARMO Institute for Drug Outcome Research

Completed

Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists

Pneumonia | Gastroenteritis | Seizures | Failure to Thrive | Hospitalized Cases of Angioneurotic Oedema | Acute Interstitial Nephritis and Thrombocytopenia

Netherlands
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Innovive Pharmaceuticals

Completed

Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesothelioma

Myelodysplastic Syndromes | Leukemia | Lung Cancer | Malignant Mesothelioma | Primary Peritoneal Cavity Cancer

United States
New York Medical College

Unknown

Trial of Cladribine, Cytarabine, Mitoxantrone, Filgrastim (CLAG-M) in Relapsed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Chronic Myelogenous Leukemia | Burkitts Leukemia/Lymphoma

United States
ViiV Healthcare
GlaxoSmithKline

Completed

HIV Treatment and CVD Events

HIV Infection | Cardiovascular Disease | Acute Myocardial Infarction | Infection, Human Immunodeficiency Virus
Laboratoires URGO

Recruiting

Efficacy and Tolerance of URGO AWC_008 and URGO AWC_022 Dressings (EXPANSION)

Wound Infection | Diabetic Foot Ulcer | Venous Leg Ulcer | Pressure Ulcer | Acute Wounds

France
Cristian Deana

Recruiting

High Flow Nasal Cannula After Esophagectomy (OSSIGENA1V)

Esophageal Cancer | Postoperative Pneumonia | Postoperative Pulmonary Atelectasis | Postoperative Pneumothorax | Postoperative Infection of Incision | Postoperative Acute Myocardial Infarction

Italy
University of Alabama at Birmingham

Recruiting

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

Lymphoma, Non-Hodgkin | Multiple Myeloma | Acute Lymphoblastic Leukemia | Cytokine Release Syndrome | ICANS

United States
CellCentric Ltd.

Recruiting

Study to Evaluate CCS1477 in Haematological Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Non Hodgkin Lymphoma | Peripheral T Cell Lymphoma | Haematological Malignancy | Higher-risk Myelodysplastic Syndrome

United Kingdom, United States, France, Sweden, Spain
Omar Aljitawi

Recruiting

Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Myelodysplastic/Myeloproliferative Neoplasm | Atypical Chronic Myeloid Leukemia | Chronic Monocytic Leukemia

United States
Novartis Pharmaceuticals

Recruiting

Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, ALL and 1L HR LBCL

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Diffuse Large B-cell Lymphoma | Small Lymphocytic Lymphoma | Large B-cell Lymphoma

Japan, Australia, Germany, Italy, Spain, France, Austria, United States
Ischemia Care LLC

Recruiting

Biomarkers of Acute Stroke in Clinic (BASIC)

Ischemia | Stroke | Ischemic Stroke | Atherosclerosis | Atrial Fibrillation | Transient Ischemic Attack | Cardiomyopathies | Thromboembolism | Stroke, Ischemic | Stroke, Acute | Thrombotic Stroke | Stroke, Complication | Cardioembolic Stroke | Cardiovascular Stroke | Atheroma | Stroke of Basilar Artery | Transient Cerebrovascular...

United States
Zimmer Biomet

Recruiting

Clinical Outcomes Study of the Nexel Total Elbow

Post-traumatic Arthritis | Degenerative Arthritis | Elbow Joint Destruction | Post-traumatic Lesions | Ankylosed Joints | Advanced Rheumatoid Arthritis | Joint Instability or Loss of Motion | Acute Comminuted Articular Fracture of Elbow Joint Surfaces | Bone Loss Contributing to Elbow Instability | Bilateral...

United States, Australia, Finland, France, Germany, Italy, Netherlands, United Kingdom
University Medical Center Groningen

Completed

RECOVAC - Long Term Efficacy and Safety of COVID-19 (SARS-CoV-2) Vaccination in Kidney Disease Patients (LESS CoV-2)

Covid19 | Chronic Kidney Diseases | SARS-CoV Infection

Netherlands
Icahn School of Medicine at Mount Sinai

Active, not recruiting

VNS for Long-COVID-19

Postural Tachycardia Syndrome | Post-COVID-19 Syndrome | Dysautonomia

United States
Laval University
Canadian Institutes of Health Research (CIHR)

Completed

Physical and Cognitive Impairments in People Suffering From Long COVID

COVID-19 | Quality of Life | Cognitive Impairment | Cognitive Dysfunction | Corona Virus Infection | Physical Disability | SARS-CoV-2 Infection | Impairment | Symptoms and Signs

Canada
Stanford University

Completed

Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantation

B-cell Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Myeloproliferative Disorder | T-cell Lymphoma

United States
Sumitomo Pharma America, Inc.

Completed

A Study of DSP-7888 Dosing Emulsion in Adult Patients With Advanced Malignancies

Melanoma | Sarcoma | Renal Cell Carcinoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Glioblastoma Multiforme

United States
Banc de Sang i Teixits

Completed

Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19 (COVIDMES)

COVID-19 | SARS-CoV 2 | Adult Respiratory Distress Syndrome

Spain
SCARE (Study group for carbapenem resistance)

Unknown

Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized Patients (DETERMINE)

Central Nervous System Infections | Pneumonia, Bacterial | Urinary Tract Infections | Intra-abdominal Infection | Osteomyelitis | Bloodstream Infection | Acute Bacterial Skin and Skin Structure Infection

Turkey
Chulalongkorn University
Mahidol University; Chiang Mai University; Phramongkutklao College of Medicine... and other collaborators

Unknown

Severe Cutaneous Adverse Reactions in Thailand (ThaiSCAR)

Drug Reaction With Eosinophilia and Systemic Symptoms | Toxic Epidermal Necrolysis | Acute Generalized Exanthematous Pustulosis | Steven-Johnson Syndrome | Generalized Bullous Fixed Drug Eruption

Thailand
Beth Israel Deaconess Medical Center
Biogen

Completed

Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis (CHAMPIONS10)

Multiple Sclerosis | Optic Neuritis | Transverse Myelitis | Acute Brainstem/Cerebellar Syndrome

United States, Canada
Celgene

Completed

A Study to Determine Final Geriatric Assessment in Haematology (GAH) Score as a Tool for Predicting Tolerance to Treatment in Elderly Patients (≥ 65 Years) With Haematologic Neoplasms

Myelodysplastic Syndromes | Multiple Myeloma | Leukemia, Lymphocytic, Chronic, B-Cell | Leukemia Myeloid Acute

Spain
University of Michigan

Completed

Magnetic Resonance Spectroscopy, Perfusion and Diffusion Tensor Imaging in Neuropsychiatric Lupus

Systemic Lupus Erythematosus | Fibromyalgia | Acute Neuropsychiatric Lupus

United States
University of Washington
Agency for Healthcare Research and Quality (AHRQ)

Completed

A Trial of Point of Care Information in Ambulatory Pediatrics

Constipation | Sinusitis | Allergic Rhinitis | Bronchiolitis | Urticaria | Pharyngitis | Croup | Acute Otitis Media

United States
National Cancer Institute (NCI)

Completed

Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse... and other conditions

United States
Children's Hospital of Philadelphia
Ilera Healthcare

Terminated

Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products (Ilera)

Epilepsy | Multiple Sclerosis | Glaucoma | Cancer | Parkinson Disease | HIV/AIDS | ALS | Autism Spectrum Disorder | Sickle Cell Disease | Spasticity, Muscle | Huntington Disease | Opioid Use | Neuropathy | Terminal Illness | Inflammatory Bowel Disease (IBD) | Intractable Pain | Ptsd | Dyskinetic Syndrome

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation

Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Recurrent Hodgkin Lymphoma | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Recurrent Small Lymphocytic Lymphoma | Blastic Plasmacytoid Dendritic Cell Neoplasm | Prolymphocytic Leukemia and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); The Wayne D. Kuni and Joan E. Kuni Foundation

Completed

Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancer

Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Refractory Hodgkin Lymphoma | Previously Treated Myelodysplastic Syndrome | Recurrent Mantle Cell Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Refractory Plasma Cell Myeloma | Recurrent Small Lymphocytic Lymphoma | Refractory... and other conditions

United States
National Cancer Institute (NCI)

Completed

Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Immunoblastic... and other conditions

United States
University of Bern
Novartis; University Hospital Inselspital, Berne; Schweizerische Multiple Sklerose... and other collaborators

Recruiting

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Multiple Sclerosis | Optic Neuritis | Neuromyelitis Optica Spectrum Disorder | CNS Sarcoidosis | CNS Vasculitis | Transverse Myelitis | Rasmussen Encephalitis | Acute Disseminated Encephalomyelitis | Anti-NMDAR Encephalitis | Anti-GAD65 Associated Autoimmune Encephalitis | Anti-AMPAR-1/2 Associated Autoimmune... and other conditions

Switzerland
Universidad de Granada
Spanish Society of Community Pharmacy; Pharmaceutical Association, Valencia... and other collaborators

Completed

Implementation of a Minor Ailment Service in Community Pharmacy Practice (INDICA+PRO)

Hyperhidrosis | Burns | Musculoskeletal Pain | Vomiting | Sleep Disorder | Constipation | Diarrhea | Cough | Dermatitis | Soft Tissue Injuries | Dry Eye | Headache | Varicose Veins | Dysmenorrhea | Flatulence | Heartburn | Nasal Congestion | Hemorrhoids | Dental Trauma | Acne | Vaginal Candidiasis | Sore Throat | Cold | Rash | Red Eye | Stress Disorder... and other conditions

Spain

Clinical Trials on Acute Illness

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Drug Interventions

CROs by country

CROs in Congo, DR of

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Rare Diseases

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