Clinical Trials on Acute-on-chronic Hepatitis B Liver Failure

Total 3747 results

Nanfang Hospital, Southern Medical University

Not yet recruiting

To Optimize Therapeutic Procedures of DPMAS in ACLF Patients: a Prospective, Sigle Arm and Multicenter Study

Acute-On-Chronic Liver Failure
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Acute hemodynamiC Response To Carvedilol Predicts Survival in ACLF Patients

Acute-On-Chronic Liver Failure

India
Assiut University

Not yet recruiting

Acute on Chronic Liver Failure in Cirrhotic Patients at Assiut University Hospitals

Acute-On-Chronic Liver Failure
First Affiliated Hospital of Wenzhou Medical University

Not yet recruiting

Identification and Verification of Neutrophil Extracellular Trap Net Related Markers in Acute-on-chronic Liver Failure

Acute-On-Chronic Liver Failure
Hai Li

Not yet recruiting

Safety of UC-MSC Transfusion for ACLF Patients

Acute-On-Chronic Liver Failure

China
Nanfang Hospital of Southern Medical University

Recruiting

Platelet Transfusion in Acute-on Chronic Liver Failure

Acute-On-Chronic Liver Failure

China
Grifols Therapeutics LLC
Instituto Grifols, S.A.

Recruiting

Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5% (APACHE)

Acute-On-Chronic Liver Failure

United States, United Kingdom, Spain, Germany, Italy, Belgium, France, Austria, Denmark, Portugal
University of Leipzig

Completed

Granulocyte Colony Stimulating Factor (G-CSF) to Treat Acute-on-chronic Liver Failure

Acute-On-Chronic Liver Failure

Germany
RHEACELL GmbH & Co. KG
FGK Clinical Research GmbH; Ticeba GmbH

Terminated

Allogeneic ABCB5-positive Stem Cells for Treatment of Acute-on-Chronic Liver Failure

Acute-On-Chronic Liver Failure

Germany
Martin Pharmaceuticals

Suspended

TRimetazidine for acUte on Chronic Liver Failure STudy (TRUST)

Acute-On-Chronic Liver Failure

Spain, France, Austria, Germany, Belgium
Sun Yat-sen University

Completed

Nomogram Analysis for HBV Related Acute-on-chronic Liver Failure

Liver Failure

China
Institute of Liver and Biliary Sciences, India

Completed

To Study the Immunomodulating Effects and Safety Profile of ω3 and ω6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure

Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Prognostic Significance of Acute Change in Liver and Splenic Stiffness in Patients of Acute on Chronic Liver Failure

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Study the Role of Plasma Von Willebrand Factor Antigen (vWF) to A Disintegrin-like and Metalloproteinase With Thrombospondin Type-1 Motifs 13 (ADAMTS-13) Activity Ratio as a Predictor of Development of Extrahepatic Organ Failure in Acute on Chronic Liver Failure (ACLF) Patients.

Acute on Chronic Liver Failure

India
Xiangya Hospital of Central South University

Recruiting

Prognosis of Patients With Acute-on-chronic Liver Failure

Acute-On-Chronic Liver Failure

China
Yaqrit Ltd
University College, London; European Foundation for Chronic Liver Failure; Fakkel...

Completed

Safety and Performance Trial of DIALIVE Liver Dialysis Device in Acute On Chronic Liver Failure Patients (DIALIVE _ACLF)

Acute on Chronic Liver Failure

France, Austria, Spain, United Kingdom, Romania, Belgium, Denmark, Germany
Promethera Therapeutics

Completed

Phase II Safety Study of 2 Dose Regimens of HepaStem in Patients With ACLF (HEP101)

Acute-On-Chronic Liver Failure

Belgium, France
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy of Albumin Therapy With Standard Medical Treatment (SMT) as Compared to Standard Medical Treatment (SMT) in Improving Patient Survival and Immune Modulation in Patients With Acute on Chronic Liver Failure (ASIA Trial).

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy and Safety of Hemoperfusion or Plasma Exchange Compared to Standard Medical Therapy in Patients With Acute on Chronic Liver Failure

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Withdrawn

To Assess the Efficacy of High-Volume Plasma Exchange and GCSF Versus GCSF Alone in Patients of Acute on Chronic Liver Failure (ACLF).

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Terminated

To Study the Influence of GCSF on Natural History of Acute On Chronic Liver Failure After the Acute Phase

Acute on Chronic Liver Failure

India
Sun Yat-sen University

Unknown

UC-MSC Infusion for HBV-Related Acute-on-Chronic Liver Failure

Liver Failure
Nanfang Hospital of Southern Medical University

Unknown

Platelet Transfusion in HBV-related acute-on Chronic Liver Failure

Acute-On-Chronic Liver Failure

China
Assiut University

Completed

Pattern of Acute on Chronic Liver Failure in Patient With HCV Related Chronic Liver Disease

Acute-On-Chronic Liver Failure

Egypt
Xiangya Hospital of Central South University

Completed

The Renal Safety of Tenofovir Alafenamide in HBV-related Acute-on-chronic Liver Failure: Real-World Study

Antiviral Drugs

China
Qin Ning

Recruiting

A Study of AARC Standards on Diagnosis and Treatment of Patients With HBV-ACLF in China (AARC China Study)

HBV | Acute on Chronic Liver Failure

China
Steminent Biotherapeutics Inc.
Taipei Veterans General Hospital, Taiwan

Withdrawn

Safety Study of Stemchymal® in Acute Liver Failure (ALF)

Acute-On-Chronic Liver Failure | Acute Liver Failure | Stem Cells | Adult Stem Cells | Steminent

Taiwan
Hai Li

Completed

A Validation Cohort for ACLF Diagnosis and Prognosis (Ch-CANONIC-Val)

Liver Dysfunction | Liver Failure, Acute on Chronic

China
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Lactate Kinetics as a Predictor of Survival in ACLF With Septic Shock

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Assessment of Coagulation Profile and Haematopoietic Responses in Patients With Acute-on-chronic Liver Failure During Systemic Inflammatory Response (SIRS) and Sepsis

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Bowel Colonization With Multi-drug Resistant Bacterial Species in Hospitalized Patients With acute-on Chronic Liver Failure (ACLF), and Its Relationship With Extra-intestinal Infectious Events and Short-term Outcomes.

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

An Open-label Randomized Controlled Trial Comparing the Role of Therapeutic Plasma-exchange in Ameliorating Secondary Organ Dysfunctions in Patients With ACLF and Develop Biomarkers of Treatment Response

Acute on Chronic Liver Failure

India
Nanfang Hospital of Southern Medical University
Xiangya Hospital of Central South University; Southwest Hospital, China; The... and other collaborators

Completed

A Multicenter Prospective Study of Application of Platelet Mapping in Acute-on-chronic-liver Failure in China

Platelet | Acute on Chronic Liver Failure | Thrombelastography | Multicenter Prospective Study

China
Hai Li

Completed

Chinese CLIF-C Acute-on-Chronic Liver Disease and Liver Failure Study (Ch-CANONIC)

Liver Failure, Acute on Chronic

China
Chuncheon Sacred Heart Hospital

Suspended

Clinical Features and Natural History of Acute-on-Chronic Liver Failure in Korean Patients With Chronic Liver Disease

Chronic Liver Disease | Acute Derangement of Liver Function

Korea, Republic of
Institute of Liver and Biliary Sciences, India

Completed

Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy.

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Recruiting

Role of Fecal Microbiota in Predicting Graft Rejection and Sepsis Among Recipients of Living Donor Liver Transplant in First Year.

Liver Cirrhosis | Acute-On-Chronic Liver Failure | Acute Liver Failure

India
First Affiliated Hospital of Zhejiang University

Completed

Exploring Biomarkers Predicting the Outcome of Acute-on-chronic Liver Failure (PGE2)

Acute-On-Chronic Liver Failure | Cirrhosis and Chronic Liver Disease
Institute of Liver and Biliary Sciences, India

Completed

Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure

Cirrhosis | Chronic Liver Failure | Acute Liver Failure

India
Dr. Alexander Supady

Recruiting

Cytokine Adsorption in Acute-on-chronic Liver Failure (CYTOHEP)

Acute-On-Chronic Liver Failure | Renal Failure

Germany
Mexbrain

Not yet recruiting

Feasibility Pilot Study to Evaluate the Safety and Performance of the MEX-CD1 Medical Device in ACLF (MexACLF)

Multiple Organ Failure | Acute on Chronic Liver Failure

France
Instituto Grifols, S.A.

Completed

Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With "Acute-on-chronic Liver Failure"

Liver Failure | Liver Cirrhosis

Spain
Institute of Liver and Biliary Sciences, India

Recruiting

To Compare Relaxed Rotational Thromboelastometry Cut-offs With Standard Cut-offs for Guiding Blood Product Use Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure Patients

Liver Cirrhosis | Acute on Chronic Liver Failure

India
University College London Hospitals
Medical Research Council

Unknown

Predictive Utility of DASIMAR as a Prognostic Biomarker in Acute-on-chronic Liver Failure (ACLF) (DASIMAR)

Liver Cirrhosis

United Kingdom
Sohag University

Completed

Acute-On-Chronic Liver Failure In Cirrhotic Patients

Cirrhosis, Liver

Egypt
Postgraduate Institute of Medical Education and...

Completed

Global Coagulation Assessment in Cirrhosis and ACLF

Acute-On-Chronic Liver Failure | Cirrhosis, Liver

India
RenJi Hospital

Not yet recruiting

Transplantation for EASL-CLIF and APASL ACLF Patients: a Retrospective Cohort Study (TEA-ACLF)

Liver Cirrhosis | Acute-On-Chronic Liver Failure | Liver Transplant; Complications
Asian Institute of Gastroenterology, India

Unknown

Plasma Exchange in Acute on Chronic Liver Failure (PLEXAR)

Acute-On-Chronic Liver Failure | Cirrhosis, Liver
Institute of Liver and Biliary Sciences, India

Withdrawn

To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.

Cirrhosis

India
Ruijin Hospital

Not yet recruiting

Albumin Infusion in Inpatients With Decompensated Cirrhosis

Decompensated Cirrhosis | Acute-On-Chronic Liver Failure

China

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