Clinical Trials on Administration, Topical

Total 701 results

Peking University People's Hospital

Recruiting

Medroxyprogesterone Acetate Plus Atorvastatin in Young Women With Early Endometrial Carcinoma and Atypical Endometrial Hyperplasia

Atypical Endometrial Hyperplasia | Endometrial Carcinoma Stage I

China
National Taiwan University Hospital

Recruiting

Treatment and Vaccine Development of Mycoplasma Pneumoniae

Atypical Pneumonia

Taiwan
Wake Forest University Health Sciences
Donaghue Medical Research Foundation; Association of American Medical Colleges

Completed

HEART Pathway Implementation

Chest Pain | Acute Coronary Syndrome | Chest Pain Atypical Syndrome | Chest Pain Rule Out Myocardial Infarction

United States
Alexion Pharmaceuticals

Completed

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS (aHUS)

Atypical Hemolytic Uremic Syndrome

France, United States, Austria, Germany, United Kingdom
Malmö University
Kronoberg County Council; County Council of Halland, Sweden; Norrbottens County... and other collaborators

Recruiting

One vs Two Visits Root Canal Treatments in Infected Teeth

Pain | Apical Periodontitis | Tooth Loss | Dental Pulp Necrosis

Sweden
Dow University of Health Sciences

Completed

Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion.

Apical Periodontitis | Irreversible Pulpitis | Root Canal Infection | Periapical Abscess

Pakistan
China National Center for Cardiovascular Diseases

Not yet recruiting

Natural History of Coronary Atherosclerosis (NASCENT)

Coronary Artery Disease Progression | Optical Coherence Tomography | Atherosclerotic Lesion | Radial Wall Strain
Mario Negri Institute for Pharmacological Research

Recruiting

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy (aHUS-iPSC-EC)

Atypical Hemolytic Uremic Syndrome

Italy
Medical Park Gaziantep Hospital
Muğla Sıtkı Koçman University; Bahçeşehir University

Completed

Study of Laparoscopic Inguinal Hernia Repair

Recurrence | Hernia, Inguinal | Hernia, Femoral | Inguinal Hernia, Indirect | Inguinal Hernia, Direct | Neuralgia, Atypical | Neuralgia, Ilioinguinal | Neuralgia, Iliohypogastric Nerve

Turkey
Ondokuz Mayıs University
The Scientific and Technological Research Council of Turkey

Completed

Cryotherapy on Inflammatory Profile and Postoperative Pain Levels in Endodontic Infections

Postoperative Pain | Apical Periodontitis | Cytokine Levels

Turkey
National Cancer Institute (NCI)

Completed

3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Accelerated Phase Chronic Myelogenous Leukemia | Relapsing Chronic Myelogenous Leukemia | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Philadelphia Chromosome Negative Chronic Myelogenous... and other conditions

United States
Centre Hospitalier Universitaire, Amiens
Centre Henri Becquerel; Hôpital Jeanne de Flandre LIlle

Recruiting

Evaluation of Optical Genome Mapping in Phi Negative Myeloproliferative Neoplasia in the Detection of Acquired Cytogenetic Abnormalities (MYELOCARTOCH)

Myeloproliferative Neoplasm | Optical Genome Mapping | Cytogenetics | Clonality | Prognostic Stratification

France
London School of Hygiene and Tropical Medicine
Bandim Health Project; Medical Research Council Unit, The Gambia; Ministerio... and other collaborators

Recruiting

Adjunctive Ivermectin Mass Drug Administration for Malaria Control (MATAMAL)

Lymphatic Filariasis | Scabies | Malaria,Falciparum | Strongyloidiasis | Neglected Tropical Diseases | Hook Worm | Soil Transmitted Helminths

Guinea-Bissau
Mitsubishi Tanabe Pharma Corporation

Completed

A Clinical Pharmacological Study of MT-3921 in Subjects With HTLV-1 Associated Myelopathy (HAM)

HTLV-1-Associated Myelopathy (HAM)

Japan
UNC Lineberger Comprehensive Cancer Center
Golfers Against Cancer Grant

Active, not recruiting

Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

Endometrial Cancer | Complex Atypical Hyperplasia

United States
Rosemary Claire Roden
Children's Miracle Network

Enrolling by invitation

Oral Naltrexone In Pediatric Eating Disorders (ONPED)

Bulimia Nervosa | Impulsive Behavior | Purging (Eating Disorders) | Eating Disorders | Eating Disorders in Adolescence | Anorexia Nervosa/Bulimia | Anorexia in Adolescence | Anorexia Nervosa, Atypical | Anorexia Nervosa, Binge Eating/Purging Type

United States
GlaxoSmithKline
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, Pharmacokinetics and Antiviral Activity of IONIS-HBVRx in Treatment-Naïve Patients With Chronic HBV Infection

Hepatitis B | Chronic Hepatitis B Atypical

Korea, Republic of, Hong Kong
European Institute of Oncology
Ministero della Salute, Italy

Recruiting

Excisional Vacuum-Assisted Breast Biopsy

Ductal Carcinoma in Situ | Atypical Ductal Hyperplasia

Italy
Kevin Winthrop
The University of Texas Health Science Center at Tyler; Insmed Incorporated

Completed

Liposomal Amikacin for Inhalation (LAI) in the Treatment of Mycobacterium Abscessus Lung Disease

Mycobacterium Infections, Nontuberculous | Mycobacteria, Atypical

United States
Alexion Pharmaceuticals

Completed

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS (aHUS)

Atypical Hemolytic Uremic Syndrome

France, United States, Austria, Germany, United Kingdom
National University Hospital, Singapore

Active, not recruiting

Selective Caries Removal (SCR) Versus Pulpotomy in Preventing Pulp Necrosis and Apical Periodontitis

Dental Caries

Singapore
Universidad Central de Venezuela
Instituto Venezolano de Investigaciones Cientificas

Completed

Transplantation of Allogeneic MSC in Patients With Pulp Necrosis and Chronic Apical Periodontitis (MSC)

Apical Periodontitis | Pulp Necroses

Venezuela
Biruni University

Completed

Effect of Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical Periodontitis

Postoperative Pain | Apical Periodontitis

Turkey
National Cancer Institute (NCI)

Active, not recruiting

Exemestane in Treating Patients With Complex Atypical Hyperplasia of the Endometrium/Endometrial Intraepithelial Neoplasia or Low Grade Endometrial Cancer

Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia | FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma | FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma | Atypical Hyperplasia

United States
Children's Hospital of Philadelphia
National Institute of Neurological Disorders and Stroke (NINDS); Vanderbilt...

Recruiting

Neurophysiologic Biomarkers in Rett Syndrome

Rett Syndrome | Rett Syndrome, Atypical | RTT

United States
jiaoliqun

Recruiting

Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis (OCT-ICAS)

Ischemic Stroke | Plaque, Atherosclerotic | Intracranial Atherosclerosis | Artery Stenosis | Optical Coherence Tomography

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors

Primary Hyperparathyroidism | Parathyroid Gland Carcinoma | Parathyroid Gland Adenoma | Parathyroid Gland Atypical Adenoma

United States
National Institutes of Health Clinical Center (CC)

Completed

X-Ray Mammography Standard of Care Protocol

Breast Cancer | Invasive Carcinoma | Atypical Ductal Hyperplasia | In Situ Carcinoma | Fibrocystic Changes

United States
Xiang Wei

Recruiting

Transapical Beating-heart Myectomy for the Treatment of Apical Hypertrophic Cardiomyopathy

Apical Hypertrophic Cardiomyopathy

China
Ain Shams University

Completed

Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled Trial

Pain, Postoperative | Apical Periodontitis | Irreversible Pulpitis

Egypt
Xiaojun Chen

Recruiting

Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia

Atypical Endometrial Hyperplasia | Fertility Issues | Overweight and Obesity

China
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients

Atypical Endometrial Hyperplasia | Endometrial Neoplasms | Progesterone Resistance

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy

Atypical Endometrial Hyperplasia | Endometrial Carcinoma

United States
Rabin Medical Center

Unknown

A Trial of Pembrolizumab for Refractory Atypical and Anaplastic Meningioma

Hemangiopericytoma | Atypical Meningioma | Anaplastic Meningioma

Israel
UNC Lineberger Comprehensive Cancer Center
Radiological Society of North America

Recruiting

18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone Therapy

Endometrial Cancer | Complex Atypical Hyperplasia

United States
Fondazione I.R.C.C.S. Istituto Neurologico Carlo...
Azienda Socio Sanitaria Territoriale Nord Milano

Active, not recruiting

A Model of Hospital-Territory Management Coordinated by a Case Manager to Improve the Care of Patients With Parkinsonism. (PROUD)

Parkinson Disease | Nurse-Patient Relations | Atypical Parkinsonism | Nurse Physician Relations | Secondary Parkinsonism

Italy
Cairo University

Not yet recruiting

Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.

Post-operative Pain
Postgraduate Institute of Dental Sciences Rohtak

Completed

Effect of Primary Non-surgical Endodontic Therapy on Glycaemic Control in Type 2 Diabetic Patients With Asymptomatic Apical Periodontitis

Apical Periodontitis | Diabete Type 2

India
AO GENERIUM

Completed

Observational Study of Elizaria® in aHUS Patients

Atypical Hemolytic Uremic Syndrome | aHUS

Russian Federation
Liverpool University Hospitals NHS Foundation Trust

Completed

Mersey Acute Coronary Syndrome Rule-Out Using High Sensitive Troponin (MACROS)

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Chest Pain | Angina Pectoris | Acute Coronary Syndrome | Angina, Unstable | Heart Attack | Chest Pain Atypical Syndrome
Shandong University

Completed

Artificial Intelligence for Early Diagnosis of Esophageal Squamous Cell Carcinoma

Artificial Intelligence | Optical Enhancement Endoscopy | Magnifying Endoscopy

China
Alexion Pharmaceuticals

Terminated

Evaluation of Potential Predictors of Disease Progression in Participants With Atypical Hemolytic Uremic Syndrome (aHUS) Including Genetics, Biomarkers, and Treatment (EVIDENCE)

Atypical Hemolytic Uremic Syndrome

United States, Australia, Germany, United Kingdom
Shandong University

Unknown

Early Detection of Head and Neck Superficial Squamous Cell Carcinoma in Patients With Esophagus Squamous Cell Carcinoma

Optical Enhancement Endoscopy

China
Alnylam Pharmaceuticals

Withdrawn

A Study of an Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome

Atypical Hemolytic Uremic Syndrome

Sweden, Moldova, Republic of, Latvia, Lithuania, Estonia, Bosnia and Herzegovina, Canada, Georgia, Macedonia, The Former Yugoslav Republic of, Serbia
Alexion

Completed

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS (aHUS)

Atypical Hemolytic Uremic Syndrome

Canada, United Kingdom, France, Germany, Netherlands, Sweden, Italy
Beijing Obstetrics and Gynecology Hospital

Not yet recruiting

Conservative Treatment for Atypical Endometrial Hyperplasia and Early Endometrial Cancer

Atypical Endometrial Hyperplasia and Endometrial Cancer
Amylyx Pharmaceuticals Inc.

Recruiting

AMX0035 and Progressive Supranuclear Palsy (ORION)

Neurodegenerative Diseases | Progressive Supranuclear Palsy | Atypical Parkinsonism | PSP

United States
University Health Network, Toronto

Recruiting

Bariatric Surgery for Fertility-Sparing Treatment of Atypical Hyperplasia and Grade 1 Cancer of the Endometrium (B-FiERCE)

Bariatric Surgery Candidate | Endometrial Cancer | Atypical Hyperplasia

Canada
Johns Hopkins University
Novartis

Enrolling by invitation

Retinal Atrophy and Neurofilament Light Chain in People With Multiple Sclerosis Taking Ofatumumab

Multiple Sclerosis | Retinal Degeneration | Visual Acuity | Tomography, Optical Coherence

United States
Omeros Corporation

Unknown

Safety and Efficacy Study of OMS721 in Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Thrombotic Microangiopathies | Atypical Hemolytic Uremic Syndrome

United States

Clinical Trials on Administration, Topical

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