Clinical Trials on Adult-Onset Growth Hormone Deficiency

Total 1144 results

Garcia, Jose M., MD, PhD

Completed

Metabolic and QOL Effects of GH Treatment in Patients With TBI and AGHD

Adult-Onset Growth Hormone Deficiency

United States
Novo Nordisk A/S

Completed

Effect of Somatropin on Left Ventricular Mass in Growth Hormone Deficient Adult Patients

Growth Hormone Disorder | Adult Growth Hormone Deficiency

France
Novo Nordisk A/S

Completed

Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Denmark
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Adults (NordiWIN)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Germany
Altus Pharmaceuticals

Completed

Study of an Extended-Release, Crystalline Formulation of Recombinant Human Growth Hormone (ALTU-238) in Growth Hormone Deficient Adults to Determine Pharmacokinetics, Pharmacodynamics, and Drug Safety

Adult Growth Hormone Deficiency

United States
OPKO Health, Inc.

Completed

MOD-4023 (Long-Lasting Human Growth Hormone (hGH)) Study in Growth Hormone Deficient Adults (GHDA)

Adult Growth Hormone Deficiency

Czechia, Hungary, Israel, Serbia, Slovakia, Slovenia
Novo Nordisk A/S

Completed

A Single Dose Trial in Healthy Caucasians and Japanese Subjects Investigating the Pharmacokinetics of Somatropin

Healthy | Growth Hormone Disorder | Adult Growth Hormone Deficiency

United States
Novo Nordisk A/S

Completed

An Observational Study Validating a Score That Quantifies the Therapeutic Response to Treatment With Norditropin® (GET)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Germany
AEterna Zentaris

Completed

Investigation of a New, Oral Growth Hormone Secretagogue, AEZS-130 as a Growth Hormone Stimulation Test.

Diagnosis of Adult Growth Hormone Deficiency (AGDH)

United States
Merck KGaA, Darmstadt, Germany

Completed

Metabolic Endocrinology and Growth Hormone in Adults (MEGHA FRANCE)

Adult Growth Hormone Deficiency
University Hospital Birmingham

Recruiting

The Effects of Growth Hormone Treatment Discontinuation in Adults on Metabolic Profile, Body Composition and Quality Of Life (GAMBOL Study) (GAMBOL)

Adult Growth Hormone Deficiency

United Kingdom
Odense University Hospital

Unknown

Bone Structure in Patients With Adult Onset Growth Hormone Deficiency Assessed Using High Resolution Peripheral Quantitative Computed Tomography

Adult Onset Growth Hormone Deficiency

Denmark
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Slovakia
Novo Nordisk A/S

Completed

A Single Dose Trial in Growth Hormone Deficient Children Investigating Safety, Pharmacokinetics and Pharmacodynamics of Long Acting Growth Hormone

Growth Hormone Disorder | Growth Hormone Deficiency in Children

Israel, Denmark, Belgium, Spain, Macedonia, The Former Yugoslav Republic of, Turkey, United Kingdom, France, Slovenia, Czech Republic
Novo Nordisk A/S

Withdrawn

An Observational Study on Treatment Compliance by Children Treated With Growth Hormone (IMPACT)

Growth Hormone Disorder | Growth Hormone Deficiency in Children
Novo Nordisk A/S

Completed

First Human Dose Trial of NNC0195-0092 (Somapacitan) in Healthy Subjects

Healthy | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Germany
Eli Lilly and Company

Completed

A Prospective Observational Study of Effect of Somatropin on Growth Hormone Deficient Adults (HypoCCS)

Hypopituitarism | Pituitary Insufficiency | Growth Hormone Deficiency, Adult
Teva Pharmaceutical Industries, Ltd.

Terminated

A Phase 2, Safety and Dose-Finding Study in Treatment-Naive, Pre-Pubertal, Growth Hormone-Deficient Children

Growth Hormone-Deficiency

Belarus, Bulgaria, Georgia, Greece, Hungary, Israel, Poland, Romania, Russian Federation, Serbia, Spain, Turkey, Ukraine
OPKO Health, Inc.

Completed

Safety and Efficacy Phase 2 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

Pediatric Growth Hormone Deficiency

Greece, Hungary, Slovakia
Novo Nordisk A/S

Completed

Observational Study of Norditropin NordiFlex® With NordiFlex PenMate™

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Delivery Systems

Germany, Netherlands, Sweden
OPKO Health, Inc.

Completed

Long Term Follow up Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

Growth Hormone Deficiency (GHD)

United States, Belarus, Greece, Hungary, Russian Federation, Ukraine
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Bioavailability Study of Two Different PEG-rhGH Preparations.

Pediatric Growth Hormone Deficiency (PGHD)

China
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Clinical Trail to Compare Pharmacokinetics of Two PEG-rhGH Injections With Different Preparations

Pediatric Growth Hormone Deficiency (PGHD)

China
Novo Nordisk A/S

Completed

Validation of a Questionnaire That Identifies the Reasons for Non-adherence to Existing Growth Hormone Therapy

Growth Hormone Deficiency in Children

Germany
Novo Nordisk A/S

Completed

A Trial Investigating the Safety, Tolerability, Availability and Distribution in the Body of Once-weekly Long-acting Growth Hormone (Somapacitan) Compared to Once Daily Norditropin NordiFlex® in Adults With Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Denmark, Sweden
Novo Nordisk A/S

Completed

A Trial to Evaluate the Safety of Once Weekly Dosing of Somapacitan (NNC0195-0092) and Daily Norditropin® FlexPro® for 52 Weeks in Previously Human Growth Hormone Treated Japanese Adults With Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
Novo Nordisk A/S

Completed

Long-term Trial on Growth Hormone Deficiency in Adults (GHDA)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
Novo Nordisk A/S

Completed

Growth Hormone Deficiency in Adults (GHDA)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
Novo Nordisk A/S

Completed

Trial to Compare the Efficacy and Safety of NNC0195-0092 (Somapacitan) With Placebo and Norditropin® FlexPro® (Somatropin) in Adults With Growth Hormone Deficiency. (REAL 1)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

United States, Poland, India, Japan, Russian Federation, United Kingdom, Germany, Sweden, Israel, Malaysia, Turkey, South Africa, Australia, Latvia, Lithuania, Romania, Brazil, Norway, Ukraine
Novo Nordisk A/S

Completed

French National Registry of Adults With Growth Hormone Deficiency Treated With Somatropin

Growth Hormone Disorder | Adult Growth Hormone Deficiency

France
Novo Nordisk A/S

Completed

A Trial to Compare the Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® FlexPro® for 26 Weeks in Previously Human Growth Hormone Treated Adults With Growth Hormone Deficiency (REAL 2)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Denmark, France, Germany, Japan, Sweden, United Kingdom
Novo Nordisk A/S

Completed

Effect of Growth Hormone on Bone Mineral Density in Young Adults With Child-hood Onset Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Sweden, Austria, Spain, Switzerland, Germany, France, Australia, Poland, United Kingdom, Norway, Belgium, Hungary
Novo Nordisk A/S

Completed

Assessing the Minimal Important Difference (MID) of the Treatment Related Impact Measure-Adult Growth Hormone Deficiency (TRIM-AGHD)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

United States
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Bioequivalence Study of Two Different PEG-rhGH Preparations.

Pediatric Growth Hormone Deficiency (PGHD)

China
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Clinical Trial to Compare Pharmacokinetics of Two Different PEG-rhGH Preparations

Pediatric Growth Hormone Deficiency (PGHD)

China
Pfizer

Recruiting

Ngenla Subcutaneous Injection Special Investigation

Growth Hormone Deficiency Without Epiphyseal Closure

Japan
Novo Nordisk A/S

Terminated

Cardiovascular Effects on Growth Hormone Therapy in Adults With Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Greece
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Various Degrees of Impaired Renal Function Compared to Subjects With Normal Renal Function

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Germany
Ipsen

Completed

A Post Marketing Surveillance Study for NutropinAq® in Adults With Growth Hormone Deficiency

Growth Hormone Disorders

United Kingdom
Pfizer

Not yet recruiting

Korean Post-marketing Surveillance Ngenla® Pre-filled Pen Injection for the Treatment of Pediatric Patients With Growth Disturbance Due to Insufficient Secretion of Growth Hormone

Pediatric Growth Hormone Deficiency
LG Life Sciences
BioPartners GmbH

Unknown

Treatment of Children With Insufficient Secretion of Growth Hormone (BPLG-004)

Growth Hormone Deficiency (GHD)

United States
University of Aarhus
Aarhus University Hospital

Unknown

Effects of Growth Hormone and IGF-1 on Anabolic Signals and Stem Cell Recruitment in Human Skeletal Muscle

Growth Hormone Deficiency | Growth Hormone Treatment

Denmark
EMD Serono

Completed

Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone Deficiency

Pituitary Dwarfism | Childhood-onset Growth Hormone Deficiency

United States
Novo Nordisk A/S

Completed

Long-term Trial on Growth Hormone Deficiency in Adults (GHDA)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
Novo Nordisk A/S

Completed

Observational Study of the Safety and Efficacy of Norditropin® in Adult Patients With Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
GeneScience Pharmaceuticals Co., Ltd.

Unknown

Extension Study of Pegylated Somatropin to Treat Growth Retardation Caused by Endogenous Growth Hormone Deficiency in Children

Growth Retardation

China
Novo Nordisk A/S

Enrolling by invitation

A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information

Adult Growth Hormone Deficiency

United States, Saudi Arabia, Germany, Slovenia
Versartis Inc.
Premier Research Group plc

Completed

Versartis International Trial in Adults With Long-Acting Growth Hormone (VITAL)

Adult Growth Hormone Deficiency

United States, Australia, Germany, United Kingdom
Eli Lilly and Company

Completed

Extension Study on Safety of Long-Term Growth Hormone Replacement in Adult Patients With Growth Hormone Deficiency

Adult Growth Hormone Deficiency

Japan
Ascendis Pharma Endocrinology Division A/S

Active, not recruiting

A Trial to Investigate Long Term Efficacy and Safety of Lonapegsomatropin in Adults With Growth Hormone Deficiency

Endocrine System Diseases | Adult Growth Hormone Deficiency | Hormone Deficiency

United States, Armenia, Georgia, Greece, Ukraine, Australia, Canada, France, Israel, Italy, Japan, Malaysia, Poland, Romania, Serbia, Slovakia, Spain, Turkey, United Kingdom, Germany, Korea, Republic of

Clinical Trials on Adult-Onset Growth Hormone Deficiency

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