Clinical Trials on Advanced Hematological Malignancies in France

Total 2646 results

Molecular Partners AG

Terminated

First-in-human Safety and Tolerability of MP0317 in Patients With Relapsed/Refractory Advanced Solid Tumors

Advanced Malignant Solid Tumor

Netherlands, France
Amgen

Terminated

Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 397 in Subjects With Selected Relapsed or Refractory Hematological Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | AML | Myelodysplastic Syndrome | MDS | Non-Hodgkins Lymphoma | NHL

United States, Australia, Italy, France, Greece, Japan
Assistance Publique - Hôpitaux de Paris

Withdrawn

Impact of Systematic Imaging for Follow up of Patients With Ovarian, Fallopian Tube or Primary Peritoneum Cancer (QUALOV)

Advanced Stage Serous Epithelial Cancer of the Ovary | Advanced Stage Cancer of Tubes | Advanced Stage Cancer of Peritoneum

France
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-87890387 for Advanced Solid Tumors

Advanced Solid Tumors

United States, France, Spain
Centre Oscar Lambret
Canceropôle Nord Ouest

Recruiting

Superiority Trial Evaluating Digitalized Information Media for Patients With Advanced Sarcomas Receiving Second Line Treatment. (ePPS-2202)

Sarcoma Metastatic | Locally Advanced Soft Tissue Sarcoma

France
Mundipharma Research Limited

Active, not recruiting

Study of Tinostamustine, First-in-Class Alkylating HDACi Fusion Molecule, in Relapsed/Refractory Hematologic Malignancies

Multiple Myeloma | Hodgkin's Lymphoma | Hematological Malignancies | Cutaneous T Cell Lymphoma

France, United States, Netherlands, Spain, Switzerland, Germany, Italy
Nerviano Medical Sciences

Terminated

Study of NMS-1116354 in Advanced/Metastatic Solid Tumors

Advanced/Metastatic Solid Tumors

France
Centessa Pharmaceuticals (UK) Limited
LockBody Therapeutics Ltd

Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of LB101 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

United States, France
Vall d'Hebron Institute of Oncology
Taisho Pharmaceutical Co., Ltd.; Roche Pharma AG; Iqvia Pty Ltd; Janssen, LP

Recruiting

A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets) (BoB)

Advanced Solid Tumor

Spain, France, Germany, Netherlands, Sweden, United Kingdom, Italy
PharmaMar

Recruiting

PM14 Administered Intravenously to Patients With Advanced Solid Tumors

Advanced Solid Tumor

United States, Spain, France
Assistance Publique - Hôpitaux de Paris

Recruiting

Do Patients Want to Engage in Discussions Dedicated to Anticipating (DDA) Their Preferences of Care in the Event of Worsening Health Status? (ESOP)

Neoplasm Metastasis | Advanced Cancer | Locoregional Neoplasm

France
MedImmune LLC

Completed

A Phase 1/2, Open-label Study to Evaluate the Safety and Antitumor Activity of MEDI0680 (AMP-514) in Combination With Durvalumab Versus Nivolumab Monotherapy in Participants With Select Advanced Malignancies

Kidney Cancer | Clear Cell Renal Cell Carcinoma | Select Advanced Malignancies

United States, France, Canada, United Kingdom, Netherlands, Australia
UNICANCER
Pfizer; National Cancer Institute, France; Fondation ARC

Completed

Phase 2 Study Assessing Efficacy and Safety of Crizotinib in Patients Harboring an Alteration on ALK, MET or ROS1 (AcSé)

Metastatic Cancer | Solid Tumors | Hematologic Cancers

France
Takeda

Completed

A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors

Carcinoma, Advanced ALK+ or ROS1+Non-Small-Cell Lung, Neoplasm, Advanced ALK+ or ROS1+Solid Tumors

Spain, Italy, Netherlands, France
Centre Leon Berard
Roche Pharma AG

Completed

Evaluation of the Added Value of a Large Molecular Profiling Panel Versus a Limited Molecular Profiling Panel in Advanced Solid Tumors. (PROFILER 02)

Advanced Solid Tumor

France
MedImmune LLC

Completed

A Multiple Ascending Dose Study of MEDI7247 in Patients With Selected Relapsed/Refractory Hematological Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Diffuse Large B-cell Lymphoma

United States, France, Korea, Republic of
University Hospital, Limoges

Recruiting

Secure Outsourcing of Carfilzomib in the Treatment of Multiple Myeloma to the Hospital at Home Setting (Carfil-HAD)

Hematological Diseases

France
Eli Lilly and Company

Completed

A Study of LY3434172, a PD-1 and PD-L1 Bispecific Antibody, in Advanced Cancer

Advanced Cancer

Belgium, United States, Korea, Republic of, Australia, France
Centre Leon Berard
NETRIS Pharma

Recruiting

NP137 Clinical and Biological Activities Assessment in Patients With Advanced/Metastatic Solid Tumors Treated by Standard Anti PD-1/PD-L1 Immunotherapies (IMMUNONET)

Advanced Solid Tumors | Metastatic Solid Tumors

France
Centre Francois Baclesse
Ligue contre le cancer, France

Recruiting

Optimize the Support of Patients in Pelvic Onco-gynecology Through Adapted Support Care in the Post-cancer Period. AFTERGYN Pilot Phase (AFTERGYN)

Long Term Cancer Side Effects | Supportive Care in Cancer | Cancer Survivorship Care Plan | Advanced Nurse Practitioner | Pelvic Gynecological Cancer

France
Institut Bergonié
AstraZeneca; National Cancer Institute, France

Not yet recruiting

MEDI5752 in Patients With Mature Tertiary Lymphoid Structures Solid Tumors. (TAYLOR)

Advanced Solid Tumor

France
University of Alberta
Alberta Health services

Active, not recruiting

A Feasibility Study of a Virtual Rehabilitation and Physical Activity Program for People With Advanced Cancer (ACTIVE-North)

Advanced Cancer

Canada
Ariad Pharmaceuticals

No longer available

An Expanded Access Study of Brigatinib for Patients With ALK-positive Advanced Non-Small Cell Lung Cancer

Carcinoma | Lung Cancer | Non-small Cell Lung Cancer | Advanced Malignancies

United States
Shanghai Henlius Biotech

Withdrawn

A Phase 1 Study of the CD73 Inhibitor(HLX23) Alone in Participants With Solid Tumor

Advanced Solid Tumor

United States
MedImmune LLC

Completed

IPH5201 as Monotherapy or in Combination With Durvalumab +/- Oleclumab in Subjects With Advanced Solid Tumors.

Advanced Solid Tumors

United States, France, Spain, Switzerland
Institut Curie

Active, not recruiting

The Integrated Support and Palliative in Cancer Day-care Hospital for Patients With Advanced Cancers: Impact on Quality of Life, Care Pathways and Support for Caregivers (HDJ-SPI)

Cancer, Advanced

France
Innate Pharma
AstraZeneca

Terminated

IPH5401 (Anti-C5aR) in Combination With Durvalumab in Patients With Advanced Solid Tumors (STELLAR-001)

Advanced Solid Tumors

United States, France
Shanghai Miracogen Inc.

Recruiting

A Study of MRG002 in Patients With HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer

Advanced Solid Tumors | Advanced or Metastatic Gastric Cancer | Advanced or Metastatic Gastroesophageal Junction Cancer

United States
Amunix, a Sanofi Company
Merck Sharp & Dohme LLC

Recruiting

To Access the Safety and Effects of Intravenous Administration of AMX-818 Alone and in Combination With Pembrolizumab in Adult Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

Locally Advanced or Metastatic HER2-Expressing Cancers

Australia, Spain, France, Portugal
University Hospital, Montpellier
University Hospital, Bordeaux; University Hospital, Toulouse

Completed

South Of France Cardiac Assist Registry (SOFCAR)

Chronic or Acute Advanced Heart Failure

France
University Hospital, Caen

Completed

Research-Action in Hematology From Hospitalization to Home (RAH HD)

Hematologic Cancer

France
Centre Oscar Lambret
Laboratoire PRISM - Michel SALZET

Recruiting

Omic Technologies to Track Resistance to Palbociclib in Metastatic Breast Cancer (OMERIC)

Advanced Breast Cancer

France
UNICANCER
Hoffmann-La Roche; National Cancer Institute, France; Fondation ARC

Active, not recruiting

Phase 2 Study Assessing Secured Access to Vemurafenib for Patients With Tumors Harboring BRAF Genomic Alterations (AcSé)

Solid Tumors | Hematologic Cancers | Metastatic Cancers

France
Arcus Biosciences, Inc.
Gilead Sciences

Recruiting

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies (EDGE-Gastric)

Gastrointestinal Tract Malignancies

United States, Korea, Republic of, France, Serbia, Canada
Bristol-Myers Squibb

Active, not recruiting

An Investigational Immunotherapy Study of BMS-986288 Alone and in Combination With Nivolumab in Advanced Solid Cancers

Advanced Cancer

France, United States, Spain, Canada, Argentina, Chile, Italy
Eli Lilly and Company

Terminated

A Tasisulam and Midazolam Drug Interaction Study in Cancer Patients

Advanced Cancer

France
Merck Sharp & Dohme LLC

Terminated

Intratumoral/Intralesional Administration of MK-4621/JetPEI™ With or Without Pembrolizumab in Participants With Advanced/Metastatic or Recurrent Solid Tumors (MK-4621-002)

Advanced Solid Tumors

France, Germany, Spain, United Kingdom
University Hospital, Bordeaux

Completed

Transplantation of Ex-vivo Expanded Cord Blood Stems Cells (GRAPA)

Malignant Haematological Disease

France
Centre Hospitalier Universitaire Dijon

Recruiting

Trial Evaluating Modified FOLFIRINOX and Modified FOLFOX in the Treatment of Locally Advanced or Metastatic Small Bowel Adenocarcinoma (FOLFORINOX SBA)

Locally Advanced or Metastatic Small Bowel Adenocarcinoma

France
Institut Paoli-Calmettes
Novartis Pharmaceuticals

Recruiting

Trans-RosaLEE Study: a Biomarker-directed, Translational Study (TransRosaLEE)

Advanced or Metastatic Breast Cancer (BC)

France
Gustave Roussy, Cancer Campus, Grand Paris
Merck Serono International SA

Completed

Biliary Cancers: EGFR INhibitor, Gemcitabine and Oxaliplatin

Advanced Biliary Cancer

France
Guangzhou Sinogen Pharmaceutical Co., Ltd
Parexel; ClinChoice Enterprise Management (Shanghai) Limited

Recruiting

Study of SGN1 in Patients With Advanced Solid Tumor

Advanced Solid Tumor

United States, China
Centre Antoine Lacassagne

Recruiting

The Enzymatic Activity of Lymphocyte Dihydropyrimidine Dehydrogenase DPD in the Blood as a Predictive and Prognostic Factor in Patients With Digestive Cancer in the First or Second Metastatic Line (DPD DIG)

Metastatic or Locally-advanced Digestive Cancer

France
Bristol-Myers Squibb

Terminated

An Investigational Immunotherapy Study of BMS-986299 Alone and in Combination With Nivolumab and Ipilimumab in Participants With Solid Cancers That Have Spread or Cannot be Removed

Advanced Cancer

United States
Xenothera SAS

Recruiting

FIH XON7 in Advanced/Metastatic Solid Tumors (FIPO23)

Metastatic Cancer | Advanced Solid Tumor

France, Belgium
UNICANCER

Recruiting

Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma Patients (GERICO14)

Advanced Soft-tissue Sarcoma | Metastatic Soft-tissue Sarcoma

France
Centre Leon Berard

Completed

Evaluation of ABEMACICLIB Monotherapy in Patients With Locally Advanced/Metastatic Head and Neck Cancer After Failure of Platinum and Cetuximab or Anti-EGFR-based Therapy and Harboring an Homozygous Deletion of CDKN2A, and/or an Amplification of CCND1 and/or of CDK6 (ABORL)

Head and Neck Cancer | Metastatic Cancer | Advanced Cancer

France
MedImmune LLC

Completed

A Study to Evaluate MEDI0562 in Combination With Immune Therapeutic Agents in Adult Subjects With Advanced Solid Tumors

Select Advanced Solid Tumors

United States, France, Netherlands
Institut Paoli-Calmettes

Not yet recruiting

Immunological Profile for Patients Treated With CAR-T Cells (SI-CART)

Hematologic Neoplasms

France
University Hospital, Toulouse

Unknown

Assistance Program for Outpatients Following an Allogeneic Hematopoietic Stem-cell Transplant (AMA-ALLO)

Hematologic Neoplasms

France

Clinical Trials on Advanced Hematological Malignancies in France

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