Clinical Trials on Advanced Malignant Mesothelioma in Italy

Total 551 results

Philogen S.p.A.

Terminated

Combination Therapy of F16IL2 and Doxorubicin in Solid Tumour Patients

Breast Cancer | Advanced Solid Tumor

Italy
Fondazione Policlinico Universitario Agostino Gemelli...
Merck Sharp & Dohme LLC

Recruiting

Carboplatin-Paclitaxel-Pembrolizumab in Neoadjuvant Treatment of Locally Advanced Cervical Cancer (MITO CERV 3)

Locally Advanced Cervical Cancer

Italy
Federation of Italian Cooperative Oncology Groups
Bristol-Myers Squibb; Eli Lilly and Company; Bayer; Novartis; Roche Pharma AG; Takeda; AstraZene... and other collaborators

Recruiting

National Register of Actionable Mutations (RATIONAL)

Solid Tumours in Advanced Stages

Italy
Cardarelli Hospital

Not yet recruiting

NBI for Early Diagnosis of OPMD/OSCC (NBI_Oral)

Oral Squamous Cell Carcinoma | Oral Potentially Malignant Disorder

Italy
National Cancer Institute, Naples

Active, not recruiting

Regorafenib Monotherapy as Second-line Treatment of Patients With RAS-mutant Advanced Colorectal Cancer (STREAM)

Advanced Colorectal Cancer

Italy
Novartis Pharmaceuticals

Completed

A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors

cMET-dysregulated Advanced Solid Tumors

United States, Italy, Spain, United Kingdom, Greece, Belgium, Austria, Czechia
Azienda Ospedaliero-Universitaria di Modena

Recruiting

Olaparib in PALB2 Advanced Pancreatic Cancer (PALBOLA)

Metastatic Pancreatic Cancer | Advanced Pancreatic Cancer

Italy
Sanofi

Terminated

A First-in-human Study of the Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of SAR439459 Monotherapy and Combination of SAR439459 and Cemiplimab in Patients With Advanced Solid Tumors

Malignant Solid Tumor

France, Spain, Australia, Belgium, Italy, United Kingdom, Taiwan, Estonia, Netherlands, Korea, Republic of, United States, Canada, Germany
Takeda

Completed

A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors

Carcinoma, Advanced ALK+ or ROS1+Non-Small-Cell Lung, Neoplasm, Advanced ALK+ or ROS1+Solid Tumors

Spain, Italy, Netherlands, France
Bristol-Myers Squibb

Active, not recruiting

An Investigational Study of Immunotherapy Combinations in Participants With Solid Cancers That Are Advanced or Have Spread

Advanced Cancer

France, United States, Spain, Australia, Italy, Switzerland, United Kingdom
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Unknown

Clinical Study for Adaptive Deep Brain Stimulation (aDBS)Controlled by Intracerebral Activity in Parkinson's Disease (ADBS)

Advanced Parkinson's Disease

Italy
Pfizer

Terminated

Clinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced Cancer

Advanced Cancer

Italy, United States, Canada, Spain
4SC AG

Completed

4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 Therapy (SENSITIZE)

Malignant Melanoma

Germany, Italy
Azienda Unità Sanitaria Locale della Romagna

Recruiting

Microbiological Assessment of Bile in Patients Undergone to Endoscopic Retrograde Cholangiography (ERCP): the "Microbile Registry" (Microbile)

Choledocholithiasis | Biliary Disease | Biliary Stricture | Jaundice, Obstructive | Jaundice; Malignant

Italy
Bristol-Myers Squibb

Completed

Phase II Study to Determine Predictive Markers of Response to BMS-734016 (MDX-010)

Unresectable Stage III or IV Malignant Melanoma

United States, Peru, Norway, Italy, Sweden, Denmark, Israel
Ospedale San Carlo Borromeo
Associazione Oncologica Milanese AmoLaVita ONLUS

Not yet recruiting

Cognitive Status Assessment In Elderly Patients With Active Treatment For Haematological Malignancies

Cognitive Impairment | Chemo-brain | Haematological Malignancy

Italy
Azienda Ospedaliero-Universitaria Careggi

Recruiting

PSMA Guided Approach for bIoCHEmical Relapse After Prostatectomy-PSICHE (PSICHE)

Prostate Cancer | Prostate Adenocarcinoma | Prostate Cancer Recurrent | Biochemical Relapse Fo Malignant Neoplasm of Prostate

Italy
Novartis Pharmaceuticals

Completed

A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors

cMET-dysregulated Advanced Solid Tumors

United States, Spain, Italy, Bulgaria, United Kingdom, France, Denmark
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Preoperative TPF Chemotherapy in Molecularly Selected Locally Advanced Resectable Oral Cavity Squamous Cell Cancer

Locally Advanced Resectable Oral Cavity Squamous Cell Cancer

Italy
Gustave Roussy, Cancer Campus, Grand Paris
National Cancer Institute, France; European Network for the Study of Adrenal...

Completed

First International Randomized Study in Malignant Progressive Pheochromocytoma and Paraganglioma (FIRSTMAPPP)

Malignant Progressive Pheochromocytoma and Paraganglioma (PPGL)

Italy, France, Germany, Netherlands
Careggi Hospital

Completed

Perioperative Use of Serum Creatinine and Postoperative Acute Kidney Injury (CreaPeriop)

Surgery | Acute Kidney Injury | Malignancy | Cronich Kidney Disease

Italy
Hoffmann-La Roche

Completed

Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of Selicrelumab (RO7009789) With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors

Advanced/Metastatic Solid Tumors

United States, Belgium, Denmark, Spain, Netherlands, Canada, Italy
Marina Garassino

Recruiting

Metformin Plus/Minus Fasting Mimicking Diet to Target the Metabolic Vulnerabilities of LKB1-inactive Lung Adenocarcinoma (FAME)

Advanced LKB1-inactive Lung Adenocarcinoma

Italy
University of Roma La Sapienza

Available

Magnetic Resonance-guided High-intensity Focused Ultrasound Treatment of Locally Advanced Pancreatic Cancer

Cancer | Pancreas | Locally Advanced Pancreatic Cancer | Non-invasive Treatment

Italy
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Clinical Study Comparing Different Strategies to Increase Adherence to Oral Therapies in Oncohematology

Cancer | Solid Tumor | Hematologic Malignancy | Oral Drug Administration

Italy
Chinese Academy of Sciences
City of Hope Medical Center; Fifth Affiliated Hospital, Sun Yat-Sen University and other collaborators

Recruiting

Treatment Recommendations for Gastrointestinal Cancers Via Large Language Models

Gastrointestinal Neoplasm Malignant

United States, China, Germany, Italy
Bristol-Myers Squibb

Active, not recruiting

An Investigational Immunotherapy Study of BMS-986288 Alone and in Combination With Nivolumab in Advanced Solid Cancers

Advanced Cancer

France, United States, Spain, Canada, Argentina, Chile, Italy
Incyte Corporation

Recruiting

Study of INCA32459 a LAG-3 and PD-1 Bispecific Antibody in Participants With Select Advanced Malignancies

Advanced Malignancies

Spain, United States, Belgium, Italy
Istituto Scientifico Romagnolo per lo Studio e...

Completed

Phase II Study of Hypofractionated Radio-chemotherapy With Gemcitabine Plus Oxaliplatin for Unresectable Nonmetastatic Locally Advanced Pancreatic Cancer.

Unresectable Pancreatic Cancer | Locally Advanced Pancreatic Cancer | Nonmetastatic Pancreatic Cancer

Italy
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Avelumab in Combination With M9241(NHS-IL12) (JAVELIN IL-12) (COMBO)

Advanced Solid Tumors

Spain, United States, Netherlands, Hungary, Italy, France, Belgium
Novartis Pharmaceuticals

Terminated

A Study of BLZ945 Single Agent or BLZ945 in Combination With PDR001 in Advanced Solid Tumors

Advanced Solid Tumors

Spain, Japan, Taiwan, Italy, Switzerland, Israel, United States, Singapore
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma. (HBO-RT)

High Grade Glioma | Malignant Glioma | Recurrent Glioma

Italy
European Institute of Oncology
Associazione Italiana per la Ricerca sul Cancro

Recruiting

MONDRIAN: Multi-omics Integrative Modelling for Stereotactic Body Radiotherapy in Early-stage Non-small Cell Lung Cancer (MONDRIAN)

Lung Neoplasm Malignant

Italy
Tiziana Life Sciences LTD

Terminated

Study Of Oral PHA-848125AC In Patients With Malignant Thymoma Previously Treated With Multiple Lines Of Chemotherapy

Malignant Thymoma

United States, Italy
Bellicum Pharmaceuticals

Active, not recruiting

Safety/PK Study of Gene Modified Donor T Cell Infusion in Children With Recurrent Hem Malignancies After Allo Transplant

Hematologic Malignancy

Italy
International Group of Endovascular Oncology
Azienda Sanitaria Ospedaliera

Unknown

Observational Study With Metronomic Oral Vinorelbine in Elderly Patients With Locally Advanced / Metastatic Non-small-cell Lung Cancer (NSCLC) (VINORELBINA)

Locally Advanced/ Metastatic NSCLC

Italy
Bristol-Myers Squibb

Active, not recruiting

A Study of BMS-986249 Alone and in Combination With Nivolumab in Advanced Solid Tumors

Advanced Cancer

Italy, Australia, United States, Spain, Romania, Argentina, Canada, Chile, Finland, Germany, Poland
Catholic University of the Sacred Heart

Unknown

LYmphadenectomy After NeoAdjuvant Chemotherapy (LYANA)

Advanced Ovarian Cancer (Stage III or IV) After Neoadjuvant Chemotherapy

Italy
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Ramucirumab Plus FOLFIRI Versus Ramucirumab Plus Paclitaxel in Patients With Advanced or Metastatic Gastric Cancer, Who Failed One Prior Line of Palliative Chemotherapy (RAMIRIS)

Advanced Gastric or EGJ Cancer

Germany, Austria, Italy
PMV Pharmaceuticals, Inc
Merck Sharp & Dohme LLC

Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Metastatic Cancer | Advanced Solid Tumor | Endometrial Cancer | Metastatic Solid Tumor | Other Cancer | Advanced Malignant Neoplasm | Locally Advanced

United States, Spain, Korea, Republic of, Singapore, Australia, France, Germany, Italy, United Kingdom
PharmaMar

Completed

Clinical Trial of Lurbinectedin (PM01183) in Selected Advanced Solid Tumors

Advanced Solid Tumors

Spain, United States, Belgium, France, Italy, Switzerland, Germany, Sweden, United Kingdom
Novartis Pharmaceuticals

Completed

A Phase I, Multi-center, Open Label, Drug-drug Interaction Study to Assess the Effect of Ceritinib on the Pharmacokinetics of Warfarin and Midazolam in Patients With ALK-positive Advanced Tumors

ALK-positive Advanced Tumors

Italy, Spain, Denmark, United States
Mirati Therapeutics Inc.

Recruiting

Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)

Metastatic Cancer | Advanced Cancer | Malignant Neoplasm of Lung

Spain, United States, Turkey, Korea, Republic of, Brazil, Croatia, France, Greece, Israel, Italy, Mexico, Netherlands, Poland, Romania, Serbia, Taiwan, Thailand
Novartis Pharmaceuticals

Recruiting

Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments

Advanced Solid Tumors

Switzerland, Italy, Germany, Hungary, Belgium, Korea, Republic of, Spain, Czechia, China, Canada, United States, France, Poland, Thailand, Hong Kong, Netherlands, Taiwan
Neovii Biotech

Terminated

Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer Progressing After Endocrine Treatment

Advanced Breast Cancer | Metastatic Breast Cancer

Spain, Austria, France, Germany, Italy
R-Pharm
GlaxoSmithKline

Terminated

Phase I Study of Ixabepilone Plus Lapatinib With or Without Capecitabine in the Treatment of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer

Locally Advanced or Metastatic Breast Cancer

United States, Italy, Australia
Incyte Corporation
Mirati Therapeutics Inc.

Recruiting

A Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation

Advanced Solid Tumors

United States, Italy, Spain, United Kingdom
Istituto Oncologico Veneto IRCCS
Ministry of Health, Italy

Completed

Individualized Treatment of Patients With Advanced NSCLC: Potential Application for Circulating Tumor Cells (CTC) Molecular and Phenotypical Profiling (2012/52)

Advanced Non Small Cell Lung Cancer

Italy
Pfizer

Terminated

Pre-Operative Study of PF-4691502 With Letrozole Compared To Letrozole Alone In Patients With Early Breast Cancer

Early Breast Cancer (Phase 2) | Advanced Breast Cancer (Phase 1b)

Spain, Sweden, Italy, Belgium
MedImmune LLC

Active, not recruiting

A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors

Selected Advanced Solid Tumors

Italy, Spain, United States, France, Korea, Republic of, Taiwan, Australia, Netherlands, Portugal

Clinical Trials on Advanced Malignant Mesothelioma in Italy

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