Clinical Trials on Advanced Esophageal Squamous Cell Cancer

Total 14790 results

Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy (SKYSCRAPER-07)

Esophageal Squamous Cell Carcinoma

United States, France, Spain, Australia, Korea, Republic of, Argentina, Belgium, China, Portugal, Taiwan, Japan, Germany, Poland, Thailand, United Kingdom, Switzerland, Turkey, Russian Federation, Morocco, Greece, Italy, New Zealand, South Africa and more
Sun Yat-sen University

Active, not recruiting

Toripalimab Plus Neoadjuvant Chemotherapy Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Tianjin Medical University Cancer Institute and...

Completed

The Prognostic Value of Tertiary Lymphatic Structure in Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Peking Union Medical College Hospital

Completed

Neoadjuvant Pembrolizumab Plus Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Fudan University

Completed

Sintilimab Plus Chemotherapy Followed by dCRT in Locally Advanced ESCC

Esophageal Squamous Cell Carcinoma

China
The First Affiliated Hospital of Zhengzhou University

Active, not recruiting

Anlotinib Combined With TQB2450 (PD-L1 Inhibitor) in the Treatment of Advanced Esophageal Squamous Cell Carcinoma(ESCC)

Esophageal Squamous Cell Carcinoma

China
Yuhong Li

Completed

Efficacy and Safety of TPF Induction Chemotherapy for Borderline-resectable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Completed

KN046 in Subjects With Late Stage Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
NYU Langone Health

Terminated

Immune Checkpoint Therapy With Nivolumab Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

United States
Peking University

Withdrawn

Neoadjuvant Treatment of Nimotuzumab With Chemotherapy or Radiotherapy in Resectable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Peking University
Jiangsu HengRui Medicine Co., Ltd.

Completed

Apatinib and Irinotecan Combination Treatment in Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line Treatment

Esophageal Squamous Cell Carcinoma

China
Guangzhou Institute of Respiratory Disease
Jiangsu HengRui Medicine Co., Ltd.; BGI-Shenzhen

Completed

Efficacy of Neoadjuvant PD-1 Blockade Plus Chemotherapy for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma | Immunotherapy

China
Fudan University

Unknown

A Study of Comparing Huachansu Plus Thoracic RT Versus RT Alone For ESCC

Esophageal Squamous Cell Carcinoma

China
National Cancer Institute (NCI)

Completed

A Pilot for a Case-Control Study of Esophageal Squamous Cell Carcinoma in Western Kenya

Esophageal Squamous Cell Carcinoma

Kenya
Samsung Medical Center

Withdrawn

Genome-wide Association Study

Esophageal Squamous Cell Carcinoma

Korea, Republic of
Peking University

Unknown

Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo) (ECMTPneo)

Esophageal Squamous Cell Carcinoma

China
Fudan University

Completed

Study of S-1 in Combination With Radiotherapy in Esophageal Cancer

Esophageal Squamous Cell Carcinoma

China
The First Affiliated Hospital of Zhengzhou University
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase II Study of SHR-1210 vs Placebo as Consolidation Chemotherapy After Radical Concurrent Chemoradiotherapy in Locally Advanced ESCC

Esophageal Squamous Cell Carcinoma

China
Fudan University
Fujian Cancer Hospital; Affiliated Hospital of Jiangnan University; First Affiliated... and other collaborators

Completed

A Phase III Study of Comparing Paclitaxel Plus 5-Fluorouracil Versus Cisplatin Plus 5-Fluorouracil in Chemoradiotherapy for Locally Advanced Esophageal Carcinoma

Esophageal Squamous Cell Carcinoma

China
Zhejiang Cancer Hospital
Second Affiliated Hospital, School of Medicine, Zhejiang University

Completed

Neoadjuvant Chemotherapy With Nab-paclitaxel Plus Cisplatin for Stage Ⅱ-Ⅲ Esophageal Cancer Patients (nabPCESCC)

Esophageal Squamous Cell Carcinoma

China
Fudan University
Zhejiang Cancer Hospital; The First Affiliated Hospital of Anhui Medical University and other collaborators

Unknown

Is ENI Necessary For Patients With Thoracic Esophageal Cancer After Esophagectomy And With Pathological Stage Of T1-2,N+,M0

Esophageal Squamous Cell Carcinoma

China
M.D. Anderson Cancer Center

Recruiting

Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events

Metastatic Pancreatic Carcinoma | Stage IV Pancreatic Cancer AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Stage IV Colon Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Stage IVA Colon Cancer AJCC v8 | Stage IVA Rectal Cancer AJCC v8 | Stage IVB Colon Cancer AJCC v8 | Stage IVB Rectal Cancer... and other conditions

United States
Royal Marsden NHS Foundation Trust

Completed

A Phase I/II Study of the Use of Intensity Modulated Radiotherapy (IMRT) in Cancer of the Thyroid, Larynx and Hypopharynx

Locally Advanced Larynx, Hypopharyngeal Squamous Cell Cancers | Locally Advanced Thyroid Cancers

United Kingdom
Shen Lin

Unknown

Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive System

Colorectal Cancer | Esophageal Squamous Cell Carcinoma | Biliary Tract Cancer | Targeted Therapy | HER2

China
Cytovation AS
Merck Sharp & Dohme LLC

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of CyPep-1 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic Cancers (Catalyst)

Advanced Breast Cancer | Advanced Melanoma | Advanced Head and Neck Squamous Cell Carcinoma

United States, France, Italy, Spain, Netherlands
Nang Kuang Pharmaceutical Co., Ltd.

Terminated

A Phase II Trial of Induction Chemotherapy With ND-420, Cisplatin and Fluorouracil Followed by Surgery in the Treatment of Patients With Localized Squamous Cell Carcinoma of the Esophagus

Localized Squamous Cell Carcinoma of the Esophagus

Taiwan
Baylor College of Medicine
M.D. Anderson Cancer Center; William Marsh Rice University; Instituto do Cancer... and other collaborators

Not yet recruiting

Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States

Suspected or Known Squamous Cell Neoplasia | Prior History of Squamous Cell Dysplasia and /or Neoplasia

Brazil, United States
Zhejiang Cancer Hospital

Recruiting

Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma in the Era of Immunotherapy

Adjuvant Radiotherapy

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Serplulimab Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Esophageal Squamous Cell Carcinoma

China
Sun Yat-sen University

Recruiting

Anti-PD-1 Immunotherapy Combined With SBRT for Patients With Oligometastatic ESCC

Esophageal Squamous Cell Carcinoma | Oligometastatic Disease

China
Jiangsu Cancer Institute & Hospital

Recruiting

Chemoradiation Plus Tislelizumab for Conversion Therapy of Locally Nonresectable ESCC (LATE)

Chemoradiation | Esophageal Squamous Cell Carcinoma | Tislelizumab

China
Fifth Affiliated Hospital, Sun Yat-Sen University

Recruiting

Quantitative Evaluation of Metastatic Lymph Nodes With Dynamic 18F-FDG PET/CT in Patients With ESCC

Esophageal Squamous Cell Carcinoma | Positron Emission Tomography

China
Sichuan Cancer Hospital and Research Institute

Not yet recruiting

Surveillance of Peripheral Blood of Lymphocyte and Immunocyte in Neoadjuvant Therapy Patients With Esophageal Squamous Cell Carcinoma (pLINE)

Surgery | Neoadjuvant Therapy | Esophageal Squamous Cell Carcinoma

China
Fujian Medical University Union Hospital

Recruiting

Postoperative Radiotherapy in Thoracic Esophageal Squamous Cell Carcinoma With Neoadjuvant Chemoradiotherapy

Radiation Oncology

China
Tianjin Medical University Cancer Institute and...

Active, not recruiting

Pembrolizumab Plus Paclitaxel, Cisplatin Followed by Surgery for Locally Advanced ESCC (KEYSTONE-001)

Esophageal Squamous Cell Carcinoma | Stage III

China
Sun Yat-sen University

Recruiting

Fraction Dose Escalation of Split-course Hypofractionated Concurrent Chemoradiotherapy Following Induction Chemo-immunotherapy in Unresectable Locally Advanced Esophageal Squamous Carcinoma: a Phase I Study.

Esophageal Squamous Cell Carcinoma

China
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States, Canada
Army Medical Center of PLA

Recruiting

A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Esophageal Squamous Cell Carcinoma

China
Sun Yat-sen University

Recruiting

Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma

Efficacy | Toxicity | Esophageal Squamous Cell Carcinoma

China
Guangdong Provincial People's Hospital

Recruiting

Trajectory Analysis of NLR and Its Association With Efficacy of Immunochemotherapy in ESCC.

Chemotherapy | Esophageal Squamous Cell Carcinoma | Immunotherapy

China
The First Affiliated Hospital of Soochow University

Recruiting

Correlation Between the Efficacy of Neoadjuvant Chemotherapy Combined With Immunotherapy of Operable Thoracic Esophageal Squamous Cell Carcinoma and the Metabolites of Intestinal Flora

Esophageal Squamous Cell Carcinoma | Intestinal Flora

China
Fudan University
Fujian Cancer Hospital; Jiangsu Cancer Institute & Hospital; Ningbo No.2 Hospital and other collaborators

Recruiting

Phase III Study of Concurrent Radiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma (ESO-Shanghai 15)

Esophageal Squamous Cell Carcinoma | Survival | Chemoradiotherapy

China
Second Affiliated Hospital, School of Medicine,...

Active, not recruiting

Carrelizumab, Chemotherapy and Apatinib in the Neoadjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Esophageal Squamous Cell Carcinoma

China
Baptist Health South Florida
Regeneron Pharmaceuticals

Withdrawn

Cemiplimab/Peg-Interferon-α in Advanced CSCC

Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Advanced Squamous Cell Carcinoma

United States
Fudan University

Recruiting

Comparing 61.2 Gy Radiotherapy Dose Versus 50.4 Gy Radiotherapy Dose for Locally Advanced Esophageal Carcinoma

Esophageal Squamous Cell Carcinoma

China
Fudan University

Recruiting

Local Therapy for Oligometastatic ESCC Patients Treated With PD-1 Inhibitor

Esophageal Squamous Cell Carcinoma | Oligometastatic Disease | Radiotherapy

China
Li Zhang

Recruiting

Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma | Neoadjuvant Therapies

China
Anhui Provincial Hospital

Recruiting

Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs for Local Advanced Patients With Inoperable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma | Chemoradiotherapy | Immunonutrition | Inoperable

China
Shanghai Zhongshan Hospital

Recruiting

Neoadjuvant Anti-PD-1 Plus Chemotherapy in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma | Neoadjuvant Chemoimmunotherapy

China

Clinical Trials on Advanced Esophageal Squamous Cell Cancer

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