Clinical Trials on Advanced Pancreatic Ductal Adenocarcinoma

Total 3354 results

M.D. Anderson Cancer Center

Active, not recruiting

Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer

Metastatic Rectal Adenocarcinoma | Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Stage IVA Rectal Cancer AJCC v8 | Stage IVB Rectal Cancer AJCC v8 | Stage IVC Rectal Cancer AJCC... and other conditions

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

Ovarian Endometrioid Adenocarcinoma | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Recurrent Breast Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Homologous Recombination Deficiency | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | ATM Gene Mutation | Deleterious BRCA1 Gene... and other conditions
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors

Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Other Solid Tumors | Pancreatic Ductal Carcinoma

United States
Roswell Park Cancer Institute
Ipsen

Active, not recruiting

Liposomal Irinotecan, Fluorouracil and Leucovorin in Treating Patients With Refractory Advanced High Grade Neuroendocrine Cancer of Gastrointestinal, Unknown, or Pancreatic Origin

Unresectable Pancreatic Neuroendocrine Carcinoma | Locally Advanced Digestive System Neuroendocrine Carcinoma | Locally Advanced Pancreatic Neuroendocrine Carcinoma | Metastatic Digestive System Neuroendocrine Carcinoma | Metastatic Pancreatic Neuroendocrine Carcinoma | Refractory Digestive... and other conditions

United States
Asan Medical Center

Recruiting

mFOLFIRINOX With or Without Stereotactic Body Radiotherapy in Locally Advanced Pancreatic Adenocarcinoma (SABER)

Pancreatic Adenocarcinoma | Pancreatic Cancer Non-resectable

Korea, Republic of
Ashish Manne
Ohio State University; NovoCure GmbH

Recruiting

A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer

United States
University of Southern California
National Cancer Institute (NCI); Van Andel Research Institute

Active, not recruiting

Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer

Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7 | Recurrent Gallbladder Carcinoma | Unresectable Gallbladder Carcinoma | Recurrent Hepatocellular Carcinoma and other conditions

United States
Prof. Dr. med. Dres. h.c. Jan Schmidt, MME

Recruiting

Patient-derived Organoids Drug Screen in Pancreatic Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreas Adenocarcinoma | Pancreas Cancer | Pancreas Neoplasm

Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

CT Perfusion Scans in Detecting Changes in Blood Flow to the Liver After Portal Vein Embolization

Liver and Intrahepatic Bile Duct Carcinoma

United States
Wuhan Union Hospital, China

Recruiting

Tislelizumab Combined With S-1 Plus Oxaliplatin as a Neoadjuvant Treatment in Patients With GC/GEJC

Advanced Gastric Cancer | Advanced Gastroesophageal Junction Adenocarcinoma

China
Shen Lin
RemeGen Co., Ltd.

Not yet recruiting

Real-world Study of HER2-overexpressed Advanced Solid Tumors After Progression of First-line Standard Therapy

Advanced Solid Tumor | Advanced Gastric Cancer | Advanced Gastroesophageal Junction Adenocarcinoma | HER2

China
SOFIE

Recruiting

Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers (18F-FAPI-74 GI)

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Cholangiocarcinoma | Pancreatic Ductal Adenocarcinoma | Gastrointestinal Cancers

United States
Thomas Jefferson University

Suspended

A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma

Malignant Solid Neoplasm | Gastric Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Colorectal Adenocarcinoma | Small Intestinal Adenocarcinoma | Clinical Stage III Gastric Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC... and other conditions

United States
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China

Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Other Solid Tumors | Pancreatic Ductal Carcinoma

China
UMC Utrecht
Johns Hopkins University; NYU Langone Health; University Medical Center Groningen and other collaborators

Recruiting

Improving Pancreatic Cancer Care by the Use of Computational Science and Technology (IMPACT)

Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreatic Diseases | Pancreas Adenocarcinoma | Pancreatic Cyst | Pancreas Cyst

Netherlands
MacroGenics

Recruiting

A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors

Renal Cell Carcinoma | Advanced Solid Tumor | Epithelial Ovarian Cancer | Hepatocellular Cancer | Malignant Melanoma | Pancreatic Ductal Carcinoma | Castration-Resistant Prostatic Cancer

United States
The Rogosin Institute
Vital Systems Inc.

Completed

Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer (Macrobead)

Colorectal Cancer Metastatic | Pancreatic Adenocarcinoma Metastatic | Pancreatic Adenocarcinoma Non-resectable

United States
University of Chicago

Recruiting

Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies (I-FLOAT)

Adenocarcinoma | Pancreatic Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

United States
Shanghai Juncell Therapeutics
Shanghai 10th People's Hospital

Recruiting

Study on TIL for the Treatment of Advanced Hepatobiliary-Pancreatic Cancers

Treatment Side Effects | Effects of Immunotherapy | Advanced Liver Cancers | Tumor Infiltrating Lymphocyte | Advanced Pancreatic Cancers

China
Mayo Clinic
National Cancer Institute (NCI)

Completed

Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study

Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic Carcinoma | Pancreatic Neoplasm | Locally Advanced Pancreatic Carcinoma

United States
Beijing Immunochina Medical Science & Technology...

Recruiting

Clinical Trial to Evaluate the Safety and Efficacy of IM92 CAR-T Cells Therapy in Patients With Advanced Gastric or Pancreatic Adenocarcinoma

Gastric Cancer | Pancreatic Cancer | Advanced Solid Tumors | Esophagogastric Junction Cancer

China
Astellas Pharma Global Development, Inc.

Active, not recruiting

A Phase 3 Efficacy, Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer (Spotlight)

Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer | Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer | Metastatic Gastric Adenocarcinoma or Cancer | Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma

United States, Australia, Belgium, Brazil, Canada, Chile, China, Colombia, France, Germany, Israel, Italy, Japan, Korea, Republic of, Mexico, Peru, Poland, Spain, Taiwan, United Kingdom
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Terminated

Gemcitabine Hydrochloride, and Radiation Therapy in Patients With Borderline Resectable Pancreatic Cancer

Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer

United States
HonorHealth Research Institute

Active, not recruiting

Pre-operative Treatment for Patients With Untreated Pancreatic Cancer

Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer | Unresectable Pancreatic Cancer | Neoadjuvant Pancreatic Cancer

United States
Criterium, Inc.
University of Colorado, Denver; Novartis

Terminated

Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies

Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Cholangiocarcinoma | Esophageal Adenocarcinoma | Colorectal Adenocarcinoma | Hepatocellular Adenocarcinoma

United States
Huazhong University of Science and Technology
LanZhou University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University...

Completed

Artificial Intelligence in EUS for Diagnosing Pancreatic Solid Lesions

Pancreatic Ductal Adenocarcinoma | Pancreatitis, Chronic | Pancreatic Neuroendocrine Tumor | Autoimmune Pancreatitis

China
Fusion Pharmaceuticals Inc.
AstraZeneca

Not yet recruiting

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Advanced Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Metastatic Colorectal Carcinoma

United States, Canada
Northwestern University
Robert H. Lurie Cancer Center

Completed

Ipilimumab and Gemcitabine Hydrochloride in Treating Patients With Stage III-IV or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery

Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
Blood Transfusion Centre of Slovenia

Unknown

Modulation of the Immune Response in Patients With Pancreatic Tubular Adenocarcinoma (SYSTHER)

Pancreatic Tubular Adenocarcinoma

Slovenia
Rui-hua Xu, MD, PhD

Not yet recruiting

A Phase II Study of Surufatinib Combined With Camrelizumab and mFOLFOX6 as Second-line Treatment for Advanced PRAD

Advanced Pancreatic Cancer

China
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

Germline Mutations Associated With Hereditary Pancreatic Cancer in Unselected Patients With Pancreatic Cancer in Mexico

Pancreatic Cancer | Pancreatic Adenocarcinoma

Mexico
Alpha Tau Medical LTD.

Not yet recruiting

Alpha Radiation Emitters Device for the Treatment of Pancreatic Cancer Emitters for the Treatment of Locally Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreatic Adenocarcinoma | Unresectable Pancreatic Cancer
G1 Therapeutics, Inc.

Completed

G1T48, an Oral SERD, Alone and in Combination With Palbociclib in ER-Positive, HER2-Negative Advanced Breast Cancer

Breast Cancer | Advanced Breast Cancer | Breast Neoplasm | Metastatic Breast Cancer | Stage IV Breast Cancer | Carcinoma, Ductal, Breast | Breast Cancer Female

United States, Belgium, Bulgaria, Georgia, Netherlands, Moldova, Republic of, Ukraine
Luca Cardone
University of Pisa; Azienda Ospedaliera Universitaria Integrata Verona; Catholic... and other collaborators

Recruiting

tailOred dRug repurposIng of dEcitabine in KRAS-dependeNt refracTory pAncreaTic cancEr (ORIENTATE)

Pancreatic Adenocarcinoma Metastatic | Pancreatic Adenocarcinoma Recurrent

Italy
Multitude Therapeutics Inc.
Tigermed Consulting Co., Ltd

Recruiting

AMT-151 in Patients With Selected Advanced Solid Tumours

Ovarian Cancer | Ovarian Epithelial Cancer | Lung Adenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Endometrial Cancer | Advanced Cancer | Ovarian Clear Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial... and other conditions

China, Australia
Emory University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; National Institutes... and other collaborators

Completed

Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancer

Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Recurrent Colorectal Carcinoma | Colorectal Adenocarcinoma | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVA Pancreatic... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage II Rectal Cancer AJCC v8 | Locally Advanced Rectal Carcinoma

United States
Hamilton Health Sciences Corporation

Recruiting

Pancreatic Adenocarcinoma Neoadjuvant Chemotherapy Before Surgery (PANCREAS)

Pancreatic Adenocarcinoma

Canada
Benaroya Research Institute

Recruiting

Gemcitabine & Nab-Paclitaxel in Pancreatic Adenocarcinoma With Positive Peritoneal Cytology

Pancreatic Adenocarcinoma

United States
Hellenic Cooperative Oncology Group
Eli Lilly and Company; Celgene Corporation

Completed

RAmucirumab Combined wIth Standard Nab-paclitaxel and Gemcitabine as First-line Chemotherapy in Patients With Advanced Pancreatic Adenocarcinoma (RACING)

Pancreatic Adenocarcinoma

Greece
ERYtech Pharma

Completed

Study of Eryaspase in Combination With Chemotherapy Versus Chemotherapy Alone as 2nd-Line Treatment in PAC (Trybeca-1)

Pancreatic Adenocarcinoma

United States, United Kingdom, France
National Health Research Institutes, Taiwan
National Taiwan University Hospital; China Medical University Hospital; Chang... and other collaborators

Completed

Locally Advanced or Metastatic Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma

Taiwan
Medstar Health Research Institute

Terminated

Adjuvant Intraperitoneal Gemcitabine for Resectable Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma

United States
University Hospital, Toulouse

Unknown

Biological and Clinical Database for Pancreatic Adenocarcinoma (BACAP)

Pancreatic Adenocarcinoma

France
University of Maryland, Baltimore

Completed

4D-CT for Pancreatic Adenocarcinoma in Radiotherapy Simulation (GCC 1210)

Pancreatic Adenocarcinoma

United States
Hellenic Society of Medical Oncology

Completed

Borderline Resectable or Resectable or Advanced Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma
Assistance Publique - Hôpitaux de Paris

Unknown

Neoadjuvant Chemotherapy Response Assessment by Combined PET-MRI in Borderline and Locally Advanced Pancreatic Adenocarcinoma. (PACMI)

Pancreatic Adenocarcinoma

France
The University of Hong Kong

Completed

Xeloxiri as First-line Treatment in Patients With Advanced Unresectable Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma

Hong Kong
Olympus Corporation
M.D. Anderson Cancer Center; Catholic University of the Sacred Heart; Erasme...

Completed

Spectroscopy From Duodenum

Pancreatic Adenocarcinoma

United States, Belgium, Italy

Clinical Trials on Advanced Pancreatic Ductal Adenocarcinoma

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