Clinical Trials on Advanced or Metastatic Solid Tumors Irrespective of Gene Alterations
Total 716 results
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University Health Network, TorontoBayer; AstraZeneca; Amgen; AnHeart Therapeutics Inc.; Applied Health Research Centre and other collaboratorsRecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
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AkesoNot yet recruitingMetastasis | Advanced or Metastatic Solid Tumors | MalignancyAustralia
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Syndax PharmaceuticalsCompletedSolid Tumor | Unresectable Malignant Neoplasm | Locally Advanced Malignant Neoplasm | Metastatic TumorUnited States
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Sidney Kimmel Comprehensive Cancer Center at Johns...Bristol-Myers Squibb; Vanderbilt University; Avon Breast Health Access FundActive, not recruitingMetastatic Solid Tumor | SF3B1 Gene Mutation | Spliceosome Mutation | U2AF1 Gene Mutation | SRSF2 Gene MutationUnited States
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Incyte Biosciences Japan GKCompletedAdvanced Solid Tumors | Metastatic Solid TumorsJapan
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Memorial Sloan Kettering Cancer CenterKyowa Hakko Kirin Pharma, Inc.CompletedAdvanced Solid Tumors | Metastatic Solid TumorsUnited States
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Bristol-Myers SquibbCompletedAdvanced Solid Tumors | Metastatic Solid TumorsKorea, Republic of, Canada, Australia
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Novartis PharmaceuticalsCompletedAdvanced Solid Tumors With Alterations of FGFR1, 2 and or 3 | Squamous Lung Cancer With FGFR1 Amplification | Bladder Cancer With FGFR3 Mutation or Fusion | Advanced Solid Tumors With FGFR1 Amplication | Advanced Solid Tumors With FGFR2 Amplication | Advanced Solid Tumors With FGFR3 MutationFrance, Spain, Taiwan, Germany, Netherlands, Singapore, United States, Australia, Korea, Republic of, Thailand, Israel, Italy, Turkey, Austria
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Lupin Ltd.CompletedA Study of LNP3794 in Subjects With NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsNRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsUnited Kingdom, Netherlands, Belgium
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Incyte CorporationTerminatedAdvanced or Metastatic Solid Tumors | FGFR Mutations | FGFR TranslocationsUnited States
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AbbottTerminatedAdvanced or Metastatic Solid TumorsUnited States
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Turning Point Therapeutics, Inc.TerminatedAdvanced Solid Tumor | Metastatic Solid Tumor | KRAS Mutation-Related TumorsUnited States
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University of AlbertaWithdrawnLocally Advanced Solid Tumors | Metastatic Solid TumorsCanada
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Jiangsu Simcere Pharmaceutical Co., Ltd.Shanghai Xianxiang Medical Technology Co., Ltd.; Simcere ZaimingRecruitingLocally Advanced Unresectable or Metastatic Solid TumorUnited States, China
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Erasca, Inc.Active, not recruitingAdvanced or Metastatic Solid TumorsUnited States, Australia
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Shanghai Miracogen Inc.RecruitingAdvanced Solid Tumors | Advanced or Metastatic Gastric Cancer | Advanced or Metastatic Gastroesophageal Junction CancerUnited States
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Alphamab (Australia) Co Pty Ltd.RecruitingAdvanced Solid Tumors | Metastatic Solid TumorsAustralia
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Jiangsu Simcere Pharmaceutical Co., Ltd.UnknownAdvanced Solid Tumors | Metastatic Solid TumorsChina
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingAdvanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | KRAS Gene Mutation | Metastatic Malignant Solid Neoplasm | EGFR Gene Mutation | ERBB2 Gene Amplification | ERBB2 Gene Mutation | EGFR Gene Amplification | ERBB3 Gene Mutation | ERBB4 Gene MutationUnited States
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NeuPharma, Inc.RecruitingLocally Advanced Solid Tumors | Metastatic Solid TumorsUnited States
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Istituto Scientifico Romagnolo per lo Studio e...RecruitingProstate-specific Membrane Antigen | mCRPC or Advanced/Metastatic Solid TumorsItaly
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Array Biopharma, now a wholly owned subsidiary...CompletedMetastatic Colorectal Cancer | Advanced Solid Tumors | Advanced or Metastatic Biliary CancerUnited States
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AstraZenecaActive, not recruitingLocally Advanced or Metastatic Solid TumoursUnited States, Spain, Canada, Korea, Republic of
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University of California, San FranciscoGlaxoSmithKlineRecruitingMetastatic Solid Tumor | BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene MutationUnited States
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Merck Sharp & Dohme LLCRecruitingAdvanced or Metastatic Solid TumorsUnited States, Canada, Israel, Netherlands
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OBI Pharma, IncTerminatedLocally Advanced Solid Tumors | Metastatic Solid TumorsUnited States, Taiwan
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Wuhan YZY Biopharma Co., Ltd.Active, not recruitingMetastatic or Locally Advanced Solid TumorsChina
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ImmuneOncia Therapeutics Inc.Not yet recruitingA Study of Phase2, IMC-001 In Patients With Metastatic Or Locally Advanced TMB-H Solid Tumor (TMB-H)TMB-H | Histologically or Cytologically Proven Metastatic or Locally Advanced Solid Tumors
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Nectin Therapeutics LtdMerck Sharp & Dohme LLCRecruitingCancer | Metastatic Cancer | Advanced Solid Tumor | Tumor, Solid | Locally Advanced Solid TumorUnited States, Israel
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BeBetter Med IncXiangya Hospital of Central South UniversityRecruitingAdvanced or Metastatic Solid Tumor | KRAS G12C MutationChina
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Astellas Pharma IncCompletedLocally Advanced (Unresectable) or Metastatic Solid Tumor MalignanciesJapan
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Sameek RoychowdhuryNational Cancer Institute (NCI)WithdrawnLocally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | ALK Gene Mutation | Metastatic Malignant Neoplasm in the Brain | Advanced Malignant Neoplasm | ALK Fusion Protein Expression | Metastatic Malignant Neoplasm in the Central Nervous System | ROS1 Gene Mutation | ALK Gene... and other conditionsUnited States
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Semafore PharmaceuticalsSignalRX Pharmaceuticals, Inc.CompletedCancer | Advanced or Metastatic Solid Tumors | Solid CancersUnited States
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GI Innovation, Inc.RecruitingAdvanced Solid Tumor | Metastatic Solid TumorKorea, Republic of, United States
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Xenthera, Inc.Not yet recruitingAdvanced Solid Tumor | Metastatic Solid Tumor
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Regeneron PharmaceuticalsRecruitingAdvanced Solid Tumor | Metastatic Solid TumorNetherlands
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Philogen S.p.A.RecruitingAdvanced Solid Tumor | Metastatic Solid TumorItaly, Germany, Switzerland
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Adagene IncRecruitingAdvanced/Metastatic Solid TumorsAustralia
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Adagene IncRecruitingAdvanced/Metastatic Solid TumorsSingapore, Australia, United States
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Adagene IncMerck Sharp & Dohme LLCCompletedAdvanced/Metastatic Solid TumorsUnited States
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Adagene IncActive, not recruitingAdvanced/Metastatic Solid TumorsUnited States, Australia
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PfizerKyowa Kirin Co., Ltd.TerminatedAdvanced/Metastatic Solid TumorsUnited States
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Nerviano Medical SciencesTerminatedAdvanced/Metastatic Solid TumorsUnited Kingdom, France
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Merck Sharp & Dohme LLCRecruitingAdvanced or Metastatic Solid TumorsCanada, Switzerland, United States
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Merck Sharp & Dohme LLCActive, not recruitingAdvanced or Metastatic Solid TumorsChile, Hungary, Korea, Republic of, South Africa, Spain, Japan
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BayerCompletedAdvanced or Recurrent Solid Tumor Harboring an NTRK Gene FusionJapan
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Jazz PharmaceuticalsMerck Sharp & Dohme LLCRecruitingAdvanced Solid Tumor | Metastatic Solid TumorUnited States
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PharmaEngineNot yet recruitingAdvanced Solid Tumor | Metastatic Solid Tumor
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Daiichi SankyoRecruitingAdvanced Solid Tumor | Metastatic Solid TumorUnited States, Japan
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Jazz PharmaceuticalsTerminatedAdvanced Solid Tumor | Metastatic Solid TumorUnited States