Clinical Trials on Adverse Event

Total 2154 results

Institut de Cancérologie de Lorraine

Recruiting

Comparative Study of the Quality of Life of Patients Suffering From OTOTOXICITY Due to Chemotherapy Based on Platinum Salts Fitted With a Hearing Aid Compared to Those Not Fitted. (PROTOTOX)

Quality of Life | Cancer | Hearing Disorders | Ototoxicity, Drug-Induced

France
National Cheng-Kung University Hospital

Recruiting

Strategy Therapy on Cancer Therapy-Related Cardiac Dysfunction

Heart Failure | Lymphoma | Breast Cancer | Cardiotoxicity | Chemotherapeutic Toxicity

Taiwan
University Medical Center Groningen
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Breast Cancer Long-term Outcomes on Cardiac Functioning: a Longitudinal Study (BLOC-II)

Heart Failure | Ventricular Dysfunction | Cardiotoxicity | Neoplasm, Breast

Netherlands
Urological Research Network, LLC

Recruiting

TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer (TPF-LITT)

MRI | Urinary Incontinence | Prostate Cancer | Ultrasound | Ablation | Sexual Function Disturbances | Prostate Biopsy | Adverse Effects Surgery | Urinary Function Disorders

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Breast Carcinoma | Cardiotoxicity

United States
Odense University Hospital
Aarhus University Hospital; University of Copenhagen; Aalborg University Hospital

Recruiting

Imaging Versus Cardiac Biomarker Monitored HER2 Directed Therapy in Patients With Breast Cancer (HER2BIC)

HER2-positive Breast Cancer | Cardiotoxicity

Denmark
University Hospital, Bordeaux

Recruiting

Treatment Pause Versus Treatment Continuation in IMDC Good or Intermediate Risk With Only One Adverse Prognostic Factor in mRCC Patients With an Objective Response at 12 Months of Treatment With PD1/ PDL1 ICIs + VEGFR-Tyrosine Kinase Inhibitors (SPICI)

Metastatic Renal Cell Carcinoma | Good or Only One Adverse Prognostic Factor Intermediate Risk Per IMDC Score

France
Moscow State University of Medicine and Dentistry

Recruiting

Observational Trial of Cardiotoxicity in Patients Undergoing Chemotherapy. (PROMETEY)

Heart Failure | Dilated Cardiomyopathy | Cardiotoxicity

Russian Federation
Memorial Sloan Kettering Cancer Center

Completed

Assessment for Long-Term Cardiovascular Impairment Associated With Trastuzumab Cardiotoxicity in HER2-Positive Breast Cancer Survivors

Trastuzumab Cardiotoxicity | HER2-Positive Breast Cancer Survivors

United States
Centre Hospitalier Universitaire Saint Pierre

Terminated

Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced Ototoxicity

Ototoxicity | Tinnitus | Ototoxic Hearing Loss | Ototoxic Hearing Loss, Bilateral

Belgium
Ipsen

Completed

An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome (ELECT)

Carcinoid Syndrome

United States, Turkey, Brazil, India, Ukraine, South Africa, Czechia, Latvia, Poland, Russian Federation, Serbia
Peking University Third Hospital

Unknown

Risk Assessment Model of Trastuzumab-related Cardiotoxicity in Breast Cancer Patients

Breast Cancer | Cardiac Toxicity | Antitumor Drugs

China
Solvotrin Innovations Ltd

Active, not recruiting

A Clinical Study on Adherence and Efficacy of Different Doses of Active Iron in Treatment Resistant Subjects

Iron-deficiency | Iron Deficiency Anemia | Heavy Menstrual Bleeding | Premenopause | Iron Adverse Reaction

Ireland
Ethem Unal, M.D., PhD, Associate Prof of Surgery...

Unknown

The Efficacy of Nifedipine in the Management of Preterm Labor (BOG/TH/PTL)

Preterm Birth | Preterm Labor | Preterm Labor Without Delivery | Side Effect of Drug | Preterm Labor With Preterm Delivery in Third Trimester | Calcium-Channel Blockers Toxicity
Radboud University Medical Center

Unknown

Early Detection of Cardiac Damage With CMR in Women With Breast Cancer (EARLY-CATCH)

Breast Cancer | Cardiotoxicity | Chemotherapy Induced Systolic Dysfunction

Netherlands
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms (TELEPATH)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Italy, Netherlands, Spain, Sweden, United Kingdom
University of California, Davis

Withdrawn

Topical Clobetasol for the Treatment of Toxic Epidermal Necrolysis (TEN)

Toxic Epidermal Necrolysis

United States
Cangzhou Hospital of Integrated Traditional Chinese...
Agency for Science, Technology and Research

Completed

Study on Continuous Intravenous of Unfractionated Heparin (UFH) to Treat Progressive Cerebral Infarction (UHPCI)

Acute Cerebral Ischemia | Heparin Causing Adverse Effects in Therapeutic Use | Heparin-induced Thrombosis

China
Mansoura University

Completed

Trigonal vs Non Trigonal Botox Injection in OAB.

Quality of Life | Urologic Diseases | Overactive Bladder Syndrome | Anticholinergic Syndrome
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate for Carcinoid Syndrome Therapy (TELECAST)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Spain, Sweden, United Kingdom, Netherlands
London School of Hygiene and Tropical Medicine
Armauer Hansen Research Institute, Ethiopia; Alert Hospital, Ethiopia; Homes...

Completed

Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum Leprosum

Leprosy

Ethiopia
Endo Pharmaceuticals

Terminated

Pharmacokinetics, Efficacy and Safety of an Octreotide Implant in Patients With Carcinoid Syndrome

Carcinoid Syndrome

United States
Jay F. Piccirillo, MD
Barnes-Jewish Hospital; Washington University Siteman Cancer Center

Completed

Chemotherapy-Induced Cognitive Impairment (CICI)

Cognitive Symptoms

United States
University Hospital, Antwerp
CytoSorbents Europe GmbH

Not yet recruiting

COOLEY- Study: aCute On chrOnic Liver failurE Using the cYtosorb Device (COOLEY)

Acute-On-Chronic Liver Failure | Sarcopenia | Ultrasonography | Anticoagulant Adverse Reaction

Belgium
Asociación para Evitar la Ceguera en México

Recruiting

Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial.

Methylprednisolone | Treatment | Erythropoietin | Toxic Optic Neuropathy

Mexico
Assistance Publique - Hôpitaux de Paris

Recruiting

Early Detection of Patients at Risk of Developing Anthracycline Cardiotoxicity With TEP/CT -FDG (DETECT)

Lymphoma, Non-Hodgkin | Lymphoma, Hodgkin

France
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Recruiting

AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm

Carcinoid Syndrome | Metastatic Nonfunctional Well Differentiated Neuroendocrine Neoplasm

United States
Mansoura University

Active, not recruiting

Can VI-RADS/ADC Accurately Stage Bladder Cancer??

Bladder Cancer | Diagnoses Disease | Bladder Disease | Bladder Urothelial Carcinoma | Bladder Neoplasm | MRI Contrast Media Adverse Reaction | Bladder Cancer Stage

Egypt
University of Liege

Completed

G-CSF in the Treatment of Toxic Epidermal Necrolysis (NeupoNET)

Stevens - Johnson Syndrome

Belgium
Massachusetts General Hospital

Withdrawn

Evaluating the Effect of Isotretinoin in Regulatory T-cell Function in Adverse Cutaneous Drug Eruptions (ACDEs): A Pilot Study

Toxic Epidermal Necrolysis

United States
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); University of Toronto

Active, not recruiting

Evaluation of Myocardial Changes During BReast Adenocarcinoma Therapy to Detect Cardiotoxicity Earlier With MRI (EMBRACE-MRI)

Breast Neoplasms

Canada
Chandrikha Chandrasekhara
TerSera Therapeutics LLC

Withdrawn

Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl (NET-PACS)

Diarrhea | Neuroendocrine Tumors | Carcinoid Syndrome

United States
Centre Hospitalier Universitaire Vaudois

Completed

Nutritional and Metabolic Management of Toxidermia Patients Requiring Intensive Care (TEN Metabolism) (TEN metabolism)

Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum
Vanderbilt University Medical Center
Duke University; Centers for Disease Control and Prevention; Children's Hospital...

Completed

Safety of LAIV4 in Children With Asthma

Vaccine Adverse Reaction | Vaccine Reaction | Asthma | Influenza | Asthma in Children | Wheezing

United States
Assiut University

Completed

Immune Responses in Hepatocellular Carcinoma Patients After Treatment With Direct Acting Antiviral Drugs

Drug-Induced Liver Injury

Egypt
Cliniques universitaires Saint-Luc- Université...

Terminated

Sandostatin (Octreotide LAR) May Lead to Clinical Improvement Through Receptor Occupation Optimisation (SCIROCCO)

Neuroendocrine Tumors | Carcinoid Syndrome
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Completed

Effect of Bevacizumab on Radiation-induced Brain Necrosis in Patients With Nasopharyngeal Carcinoma (BRAIN)

Nasopharyngeal Carcinoma | Adverse Effect of Radiation Therapy | Brain Necrosis

China
Istanbul Saglik Bilimleri University

Completed

Effectiveness of Mechano-Analgesia and Cold Application on Ecchymosis, Pain and Satisfaction at Subcutaneous Heparin Injection

Injection Site Reaction | Injection Site Bruising
Fudan University

Completed

Comparison Study of Doxorubicin Versus Epirubicin-induced Cardiotoxicity in Patients With DLBCL

Lymphoma

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Silymarin (Milk Thistle Extract) in Treating Patients With Acute Lymphoblastic Leukemia Who Are Receiving Chemotherapy

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
The Third Affiliated Hospital of Guangzhou Medical...

Recruiting

The Efficacy of Vosevi in Treating DAA-experienced Patients

Chronic Hepatitis C | Medication Reaction

China
Hacettepe University

Recruiting

A Morphological Study in Volleyball Athletes With Cronic Ankle Instability

Ankle Injuries | Instability; Ankle (Ligaments) (Old Injury) | Athlete Foot | Radiological Devices Associated With Adverse Incidents, Diagnostic and Monitoring Devices

Turkey
Mahidol University

Recruiting

Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trial

Hepatitis | Tuberculosis | Drug Induced Liver Injury

Thailand
NHS Greater Glasgow and Clyde
Pneumowave Ltd

Recruiting

ARM-ED: Advanced Respiratory Monitoring Events in Drug Toxicity (ARM-ED)

Respiratory Insufficiency | Overdose of Opiate | Sedative Overdose | Sedative Toxicity

United Kingdom
Fundación Centro Nacional de Investigaciones Cardiovasculares...
European Commission

Recruiting

REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs (RESILIENCE)

Lymphoma | Anthracycline-induced Cardiac Toxicity

Netherlands, Spain, Denmark, Germany, France, Portugal
LifeBridge Health

Recruiting

Quantification of Binding and Neutralizing Antibody Levels in COVID-19 Vaccinated Health Care Workers Over 1 Year

Inflammation | Vaccine Adverse Reaction | Thrombosis | Corona Virus Infection | COVID-19 Vaccine | Vaccine Response

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Treatment of Acute Lymphoblastic Leukemia in Children

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Byondis B.V.

Completed

Evaluation of Safety and Efficacy of Sodium Thiosulfate (BYON5667) Eye Drops to Reduce Ocular Toxicity in Cancer Patients Treated With SYD985

Metastatic Breast Cancer

France, Belgium, Spain
Lakehead University

Completed

Diphenhydramine and Sweating (BENEXE2022)

Hyperthermia | Allergic Rhinitis | Diphenhydramine Causing Adverse Effects in Therapeutic Use | Sweating

Canada

Clinical Trials on Adverse Event

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