Clinical Trials on Adverse Events

Total 2506 results

Azienda Ospedaliera Città della Salute e della...
University Hospital, Zürich

Completed

veRy Thin Stents for Patients With Left mAIn or bifurcatioN in Real Life: the RAIN a Multicenter Study (RAIN)

Left Main Coronary Artery Disease | Stent Thrombosis | Stent Restenosis | Coronary Bifurcations | Very Thin Stents

Italy
Paul M. Tulkens

Recruiting

Plasma Protein Binding and PK/PD of Total and Unbound Temocillin Non-ICU Patients (TEMODELTA)

Pharmacokinetics | Infection | Infections, Bacterial | Drug Monitoring | Antibacterial Agents | Temocillin

Belgium
Xijing Hospital

Unknown

In-stent Repair and Vessel Reaction of STEMI Patients With OCT

Percutaneous Coronary Intervention | ST-Elevation Myocardial Infarction | Optical Coherence Tomography | Drug-eluting Stents

China
Institut de cancérologie Strasbourg Europe

Not yet recruiting

Role of Sodium-glucose Linked Transporter 2 (SGLT2) and Its Inhibitor Over CARdiotoxicity Induced by Anthracyclines and Breast Cancer Tumorigenesis SCARA-B (SCARA-B)

Breast Neoplasms

France
Tanta University

Recruiting

Evaluation of Possible Safety and Efficacy of Fenofibrate in the Prophylaxis of Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients

Breast Cancer Stage 2 and 3

Egypt
Institut de Cancérologie de Lorraine

Recruiting

Comparative Study of the Quality of Life of Patients Suffering From OTOTOXICITY Due to Chemotherapy Based on Platinum Salts Fitted With a Hearing Aid Compared to Those Not Fitted. (PROTOTOX)

Quality of Life | Cancer | Hearing Disorders | Ototoxicity, Drug-Induced

France
National Cheng-Kung University Hospital

Recruiting

Strategy Therapy on Cancer Therapy-Related Cardiac Dysfunction

Heart Failure | Lymphoma | Breast Cancer | Cardiotoxicity | Chemotherapeutic Toxicity

Taiwan
University Medical Center Groningen
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Breast Cancer Long-term Outcomes on Cardiac Functioning: a Longitudinal Study (BLOC-II)

Heart Failure | Ventricular Dysfunction | Cardiotoxicity | Neoplasm, Breast

Netherlands
Urological Research Network, LLC

Recruiting

TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer (TPF-LITT)

MRI | Urinary Incontinence | Prostate Cancer | Ultrasound | Ablation | Sexual Function Disturbances | Prostate Biopsy | Adverse Effects Surgery | Urinary Function Disorders

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Breast Carcinoma | Cardiotoxicity

United States
Odense University Hospital
Aarhus University Hospital; University of Copenhagen; Aalborg University Hospital

Recruiting

Imaging Versus Cardiac Biomarker Monitored HER2 Directed Therapy in Patients With Breast Cancer (HER2BIC)

HER2-positive Breast Cancer | Cardiotoxicity

Denmark
University Hospital, Bordeaux

Recruiting

Treatment Pause Versus Treatment Continuation in IMDC Good or Intermediate Risk With Only One Adverse Prognostic Factor in mRCC Patients With an Objective Response at 12 Months of Treatment With PD1/ PDL1 ICIs + VEGFR-Tyrosine Kinase Inhibitors (SPICI)

Metastatic Renal Cell Carcinoma | Good or Only One Adverse Prognostic Factor Intermediate Risk Per IMDC Score

France
Moscow State University of Medicine and Dentistry

Recruiting

Observational Trial of Cardiotoxicity in Patients Undergoing Chemotherapy. (PROMETEY)

Heart Failure | Dilated Cardiomyopathy | Cardiotoxicity

Russian Federation
Memorial Sloan Kettering Cancer Center

Completed

Assessment for Long-Term Cardiovascular Impairment Associated With Trastuzumab Cardiotoxicity in HER2-Positive Breast Cancer Survivors

Trastuzumab Cardiotoxicity | HER2-Positive Breast Cancer Survivors

United States
Centre Hospitalier Universitaire Saint Pierre

Terminated

Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced Ototoxicity

Ototoxicity | Tinnitus | Ototoxic Hearing Loss | Ototoxic Hearing Loss, Bilateral

Belgium
Ipsen

Completed

An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome (ELECT)

Carcinoid Syndrome

United States, Turkey, Brazil, India, Ukraine, South Africa, Czechia, Latvia, Poland, Russian Federation, Serbia
Peking University Third Hospital

Unknown

Risk Assessment Model of Trastuzumab-related Cardiotoxicity in Breast Cancer Patients

Breast Cancer | Cardiac Toxicity | Antitumor Drugs

China
Solvotrin Innovations Ltd

Active, not recruiting

A Clinical Study on Adherence and Efficacy of Different Doses of Active Iron in Treatment Resistant Subjects

Iron-deficiency | Iron Deficiency Anemia | Heavy Menstrual Bleeding | Premenopause | Iron Adverse Reaction

Ireland
Ethem Unal, M.D., PhD, Associate Prof of Surgery...

Unknown

The Efficacy of Nifedipine in the Management of Preterm Labor (BOG/TH/PTL)

Preterm Birth | Preterm Labor | Preterm Labor Without Delivery | Side Effect of Drug | Preterm Labor With Preterm Delivery in Third Trimester | Calcium-Channel Blockers Toxicity
Radboud University Medical Center

Unknown

Early Detection of Cardiac Damage With CMR in Women With Breast Cancer (EARLY-CATCH)

Breast Cancer | Cardiotoxicity | Chemotherapy Induced Systolic Dysfunction

Netherlands
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms (TELEPATH)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Italy, Netherlands, Spain, Sweden, United Kingdom
University of California, Davis

Withdrawn

Topical Clobetasol for the Treatment of Toxic Epidermal Necrolysis (TEN)

Toxic Epidermal Necrolysis

United States
Cangzhou Hospital of Integrated Traditional Chinese...
Agency for Science, Technology and Research

Completed

Study on Continuous Intravenous of Unfractionated Heparin (UFH) to Treat Progressive Cerebral Infarction (UHPCI)

Acute Cerebral Ischemia | Heparin Causing Adverse Effects in Therapeutic Use | Heparin-induced Thrombosis

China
Mansoura University

Completed

Trigonal vs Non Trigonal Botox Injection in OAB.

Quality of Life | Urologic Diseases | Overactive Bladder Syndrome | Anticholinergic Syndrome
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate for Carcinoid Syndrome Therapy (TELECAST)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Spain, Sweden, United Kingdom, Netherlands
London School of Hygiene and Tropical Medicine
Armauer Hansen Research Institute, Ethiopia; Alert Hospital, Ethiopia; Homes...

Completed

Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum Leprosum

Leprosy

Ethiopia
Endo Pharmaceuticals

Terminated

Pharmacokinetics, Efficacy and Safety of an Octreotide Implant in Patients With Carcinoid Syndrome

Carcinoid Syndrome

United States
Jay F. Piccirillo, MD
Barnes-Jewish Hospital; Washington University Siteman Cancer Center

Completed

Chemotherapy-Induced Cognitive Impairment (CICI)

Cognitive Symptoms

United States
Hospital del Mar

Not yet recruiting

"Suture of the Tuberosities in Inverted Prostheses" Implanted for Acute Fractures of the Proximal Humerus?.

Proximal Humeral Fractures, Reverse Shoulder Prostheses, Tuberosities
Tanta University

Not yet recruiting

Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity

Breast Cancer | Doxorubicin Induced Cardiomyopathy

Egypt
University of Glasgow
NHS Greater Glasgow and Clyde; Tenovus Scotland

Recruiting

Investigating the Long-term Cardiac Sequelae of Trastuzumab Therapy

Breast Cancer | HER2-positive Breast Cancer | Cardiotoxicity

United Kingdom
Kaohsiung Medical University Chung-Ho Memorial...

Recruiting

Naldebain and Video-assisted Thoracoscopic Surgery

Analgesia | Satisfaction, Patient | Itching | Injection Site Reaction | Nausea and Vomiting, Postoperative

Taiwan
Sound Pharmaceuticals, Incorporated
Medical University of South Carolina; Cystic Fibrosis Foundation

Enrolling by invitation

SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity

Ototoxicity

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery

Breast Cancer | Cardiac Toxicity

United States
University of South Florida
National Cancer Institute (NCI)

Completed

Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab

Breast Cancer | Cardiac Toxicity

United States
Menoufia University

Enrolling by invitation

Adverse Effects of Ivermectin Used in Egypt During COVID-19

Covid19 | Drug Toxicity | Drug Side Effect | Ivermectin Poisoning

Egypt
Advanced Accelerator Applications

Terminated

99mTc-rhAnnexin V-128 Imaging and Cardiotoxicity in Patients With Early Breast Cancer

Breast Cancer | Doxorubicin Induced Cardiomyopathy

Canada
Ipsen

Terminated

Study to Assess the Efficacy and Safety of Different Doses of BIM 23A760 in Patients With Carcinoid Syndrome (CAMPANULA)

Carcinoid Syndrome

Spain, Belgium, Ireland, Czechia, Israel, France, United Kingdom, Latvia, Germany, Russian Federation, Slovakia, Italy, Netherlands, Finland, Austria, Poland, Sweden, Ukraine
Ipsen

Terminated

Comparison of Lanreotide Autogel® and Sandostatin LAR Depot in the Treatment of Clinical Symptoms Associated With Carcinoid Syndrome

Malignant Carcinoid Syndrome

United States
Luo yanrong

Completed

Different Chemotherapy Protocols Combined With Intensity Modulated Radiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma

Drug-Related Side Effects and Adverse Reactions

China
Avera McKennan Hospital & University Health Center

Terminated

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Breast Cancer | Breast Tumors

United States
Cedars-Sinai Medical Center
California Breast Cancer Research Program

Terminated

STOP Heart Disease in Breast Cancer Survivors Trial (STOP)

Breast Cancer | Heart Disease | Cardiotoxicity | Myocardial Dysfunction

United States
Lexicon Pharmaceuticals

Completed

Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome

Carcinoid Syndrome

Germany, United Kingdom
Henry Ford Health System
Helen L. Kay Charitable Trust

Completed

Prevention Using Exercise Rehabilitation to Offset Cardiac Toxicities Induced Via Chemotherapy (HF-PROACTIVE)

Leukemia | Breast Cancer | Gastric Cancer | Doxorubicin Induced Cardiomyopathy

United States
Brett King
Swedish Orphan Biovitrum

Terminated

Study to Evaluate the Use of Palifermin to Treat Toxic Epidermal Necrolysis

Stevens-Johnson Syndrome | Toxic Epidermal Necrolysis

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Comparison Between Corticosteroid and Topical Steroids in the DRESS (DRESSCODE)

Drug Rash With Eosinophilia and Systemic Symptoms

France
London School of Hygiene and Tropical Medicine
Armauer Hansen Research Institute, Ethiopia; Alert Hospital, Ethiopia; Homes...

Completed

Ciclosporin in the Management of New Erythema Nodosum Leprosum

Leprosy

Ethiopia
Columbia University

Withdrawn

Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever

Liver Failure | Liver Failure, Acute | Fever | Prevention & Control | Drug Induced Liver Injury

United States
Loyola University

Withdrawn

Study of a Potential New Treatment for Patients With Toxic Epidermal Necrolysis (TEN)

Toxic Epidermal Necrolysis
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Effects of Serotonin Excess on Bone in Carcinoid Syndrome

Carcinoid Syndrome

United Kingdom

Clinical Trials on Adverse Events

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