Clinical Trials on Aggressive Systemic Mastocytosis

Total 190969 results

M.D. Anderson Cancer Center
Novartis

Completed

RAD001 in Relapsed or Refractory AML, ALL, CML in Blastic-Phase, Agnogenic Myeloid Metaplasia, CLL, T-Cell Leukemia, or Mantle Cell Lymphoma

Leukemia | Myelofibrosis | Mantle Cell Lymphoma

United States
Sanguine Biosciences
Novo Nordisk A/S

Completed

Biorepository of Biospecimen Samples in Matched Healthy Control Participants and Participants Diagnosed With Diabetic Kidney Disease, Chronic Kidney Disease, or Type 2 Diabetes (SAN-08961)

Healthy | Chronic Kidney Diseases | Diabetic Kidney Disease | Diabetes Type 2

United States
Tonix Pharmaceuticals, Inc.

Completed

A Phase 2 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Patients With Multi-Site Pain Associated With Post-Acute Sequelae of SARS-CoV-2 Infection (PREVAIL)

COVID-19 | Long COVID | Post-Acute Sequelae of SARS-CoV-2 (PASC) Infection | Long Haul COVID

United States
M.D. Anderson Cancer Center

Completed

Clearance Of Mucus In Stents (COMIS)

Myocardial Infarction | Pneumonia | Lung Neoplasms | Respiratory Failure | Unstable Angina | Cardiac Arrhythmia | Acute Coronary Syndromes | Thromboembolic Disease

United States
Queen Mary University of London
University College, London

Completed

Comprehensive Assessment of Nutrition and Dietary Intervention in Hypermobile Ehlers Danlos Syndrome (CANDI-hEDS2)

Irritable Bowel Syndrome | Functional Gastrointestinal Disorders | Hypermobile Ehlers-Danlos Syndrome

United Kingdom
Lynkcell Europe

Enrolling by invitation

Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations

Breast Cancer | Breast Neoplasms | Ovarian Neoplasms | Ovarian Cancer | HER2-positive Breast Cancer | HER2-negative Breast Cancer | HER-2 Protein Overexpression | BRCA Mutation

Ukraine
Instituto do Cancer do Estado de São Paulo
University of Sao Paulo General Hospital

Terminated

Cryoablation of Bone Metastases From Endocrine Tumors

Neoplasm Metastasis | Neuroendocrine Tumors | Bone Metastases | Pheochromocytoma | Thyroid Neoplasm | Adrenal Neoplasm

Brazil
Seoul National University Hospital

Completed

Survival Impact of Internal Mammary or Supraclavicular Lymphadenectomy (SDLNOC)

Lymph Node Metastases | Ovarian Cancer Stage IV

Korea, Republic of
Sohag University

Completed

Effects of Adrenal Androgens on Gender-typed Behavior in Girls With Turner Syndrome

Turner Syndrome

Egypt
SÜMEYYE BİLGİLİ
Ataturk University

Completed

The Effect of Listening to Music During CPAP on the Agitation Levels and Compliance.

COVID-19 | COVID-19 Acute Respiratory Distress Syndrome

Turkey
Rennes University Hospital
Ministry of Health, France

Completed

Quantification of Liver Iron Overload and Steatosis Using Magnetic Resonance Imaging (SURFER)

Hepatitis B | Hepatitis C | Iron Overload | Metabolic Syndrome X | Alcohol Abuse

France, Spain
Nemours Children's Clinic
Genentech, Inc.

Completed

Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism

Hypogonadism | Turner Syndrome | Premature Ovarian Failure

United States, Chile
Barbara Ann Karmanos Cancer Institute

Completed

DISCO Application for the Improvement of Financial Outcomes in Patients With Hematologic Cancer

Chronic Lymphocytic Leukemia | Plasma Cell Myeloma | Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
Tessa Therapeutics

Active, not recruiting

Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma (CERTAIN)

Anaplastic Large Cell Lymphoma | Diffuse Large B Cell Lymphoma | Peripheral T Cell Lymphoma | Extranodal NK/T-cell Lymphoma | Primary Mediastinal Large B-Cell Lymphoma (PMBCL)

United States
ProQR Therapeutics

Terminated

Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, United Kingdom
University of Pittsburgh
Patient-Centered Outcomes Research Institute

Active, not recruiting

PCORI Integrated Care (IC) Models for Patient-Centered Outcomes (IC)

Depression | Hypertension | Diabetes | Arthritis | Schizophrenia | Chronic Obstructive Pulmonary Disease | Atrial Fibrillation | Asthma | Anxiety | Bipolar Disorder | Congestive Heart Failure

United States
University of Minnesota
Indiana University

Active, not recruiting

Calcium and Phosphorus Whole-Body Balance and Kinetics in Patients With Moderate Chronic Kidney Disease

Chronic Kidney Diseases | Phosphorus and Calcium Disorders | Chronic Kidney Disease Mineral and Bone Disorder

United States
Barretos Cancer Hospital

Completed

Neoadjuvant Carboplatin in Triple Negative Breast Cancer

BRCA1 Hereditary Breast and Ovarian Cancer Syndrome

Brazil
University of Baghdad

Completed

Using of Testes' Shocker in Improving Sexual Activity

Sexual Dysfunction | Erectile Dysfunction | Erectile Dysfunction Following Radical Prostatectomy | Erectile Dysfunction Following Radiation Therapy | Sexual Abstinence | Erectile Dysfunction With Diabetes Mellitus | Sexual Desire Disorder | Erectile Dysfunction Following Cryotherapy | Erectile Dysfunction... and other conditions

Iraq
National Cancer Institute (NCI)

Completed

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Chronic Lymphocytic Leukemia | Refractory Small Lymphocytic Lymphoma | Recurrent B-Cell Prolymphocytic Leukemia | Refractory B-Cell Prolymphocytic Leukemia

United States
Assistance Publique - Hôpitaux de Paris

Completed

Salt Wasting, Hydro-sodium Balance and Fludrocortisone Requirement in Congenital Adrenal Hyperplasia (NaCAH)

Congenital Adrenal Hyperplasia (CAH)

France
Minsk Scientific-Practical Center for Surgery,...
Belarusian State Medical University

Completed

Pneumococcal Vaccination of Multiple Myeloma Patients on Novel Agents

Multiple Myeloma | Febrile Neutropenia | Pneumococcal Pneumonia | Pneumococcal Infection

Belarus
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; University... and other collaborators

Completed

Evaluating Quality of Life in Patients With AIDS-Associated Kaposi Sarcoma Treated With Bleomycin and Vincristine

Human Immunodeficiency Virus 1 Positive | AIDS-Related Kaposi Sarcoma

Tanzania
University of Washington
National Cancer Institute (NCI)

Completed

High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | Refractory Acute Leukemia of Ambiguous Lineage | Recurrent Acute Leukemia of Ambiguous Lineage

United States
Freeman-Sheldon Research Group, Inc.

Terminated

Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome (STOP-FSS)

Craniofacial Abnormalities | Arthrogryposis | Freeman-Sheldon Syndrome | Arthrogryposis Distal Type 2A | Whistling Face Syndrome | Craniocarpotarsal Dysplasia | Craniocarpotarsal Dystrophy | Freeman-Sheldon Syndrome Variant | Sheldon-Hall Syndrome | Arthrogryposis Distal Type 2B | Gordon Syndrome | Arthrogryposis... and other conditions

United States
Federal University of Pelotas

Completed

Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain

Obstructive Sleep Apnea Syndrome | Bruxism | Temporomandibular Joint Disorders

Brazil
CENTOGENE GmbH Rostock

Completed

Biomarker for Hereditary AngioEdema Disease (BioHAE)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | C1 Esterase Inhibitor Deficiency | HAE | Angio Edema | C4 Deficiency | Hereditary Angioedema Type III

Turkey, Armenia, Georgia, India, Peru, Poland, Romania
Uppsala University
Karolinska University Hospital; Sahlgrenska University Hospital, Sweden; University... and other collaborators

Completed

Impact of COVID-19 After Autologous Hematopoietic Stem Cell Transplantation in Sweden (AutoCOVID-19)

Covid19 | Hematologic Neoplasms | Stem Cell Transplant Complications | Myeloma Multiple | Malignant Lymphoma

Sweden
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Prevalence of Autistic Spectrum Disorder (ASD) in Children With Haemophilia

Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder | Social Communication Disorder | Haemophilia
Pfizer
TFS Trial Form Support

Completed

Study On Fatigue- And Hand-Foot Syndrome-Related Quality Of Life In Patients With Metastatic Renal Cell Carcinoma Receiving A Tyrosine Kinase Inhibitor as First-Line Treatment (TROYA)

Metastatic Renal Cell Carcinoma

Spain
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children

HIV Infections | Bacterial Infections | Pneumonia, Pneumocystis Carinii

United States, Puerto Rico
IRCCS Policlinico S. Donato

Terminated

ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery (ZEPLAST-PED)

Bleeding | Surgery--Complications | Congenital Heart Disease | Transfusion-Related Acute Lung Injury | Cardiac Defect | Fibrinogenopenia; Acquired | Transfusion-Associated Circulatory Overload

Italy
Anna Alessandri Bonetti

Completed

Effect Of Sleep Apnea Treatment On Temporo-Mandibular Disorders

Pain | Sleep Apnea Syndromes | Sleep Apnea, Obstructive | Sleep Apnea | Temporomandibular Disorder | Pain, Face

Italy
National Cancer Institute (NCI)

Completed

Cediranib Maleate With or Without Lenalidomide for the Treatment of Thyroid Cancer

Refractory Differentiated Thyroid Gland Carcinoma | Unresectable Thyroid Gland Carcinoma | Refractory Thyroid Gland Papillary Carcinoma | Refractory Thyroid Gland Follicular Carcinoma | Refractory Thyroid Gland Hurthle Cell Carcinoma

United States, Canada
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
Kobe University
Boehringer Ingelheim

Active, not recruiting

A Extension Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance ( EMPIRE-02 ) (EMPIRE-02)

Insulin Resistance - Type A | Insulin Resistance - Type B | Lipoatrophic Diabetes Mellitus | Insulin Resistance Syndrome

Japan
University of Milan

Completed

Ultrasound Grayscale Analysis in ARDS covid19 (Graycovid)

Muscular Diseases | COVID-19 Acute Respiratory Distress Syndrome

Italy
University Hospital, Limoges

Completed

Selection of Patients With Chronic Inflammatory Rheumatism Requiring Management During the COVID-19 Pandemia (SePaRIC)

Covid19 | Rheumatoid Arthritis | Inflammatory Arthritis | Spondyloarthritis | Inflammatory Rheumatism

France
University of Waterloo
Canadian Institutes of Health Research (CIHR); YMCA; City of Lakes family Health... and other collaborators

Completed

Functional Exercise and Nutrition Education Program for Older Adults (MoveStrong)

Cardiovascular Diseases | Stroke | Kidney Diseases | Hypertension | Diabetes Mellitus | Cancer | Arthritis | Chronic Disease | Chronic Lung Disease | Congestive Heart Failure | Osteoporosis, Osteopenia | Frail

Canada
Akdeniz University

Completed

Pelvic Floor and Sexual Dysfunction in Women With Sjogren's Syndrome

Urinary Incontinence | Constipation | Sexual Dysfunction | Pelvic Organ Prolapse | Pelvic Floor Disorders

Turkey
Robert Krance
Baylor College of Medicine; The Methodist Hospital Research Institute; Center...

Completed

Donor-Derived Humoral Immunity, Hematopoietic Stem Cell Transplantation, TAR (TAR)

Hodgkin Lymphoma | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
Queen's University, Belfast
University of Sussex

Unknown

Visual Performance Measures in a Virtual Reality Environment for Assessing Clinical Trial Outcomes in Those With Severely Reduced Vision

Retinitis Pigmentosa | Low Vision | Albinism | Stargardt Disease 1 | Stargardt Disease 3 | Stargardt Disease 4

United Kingdom
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases (MALTED)

Nasopharyngeal Carcinoma | Hodgkin Lymphoma | Non-Hodgkin Lymphoma | Leiomyosarcoma | Lymphoproliferative Disorder | Severe Chronic Active EBV (SCAEBV)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

CAR.CD19-CD28-zeta-2A-iCasp9-IL15-Transduced Cord Blood NK Cells, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Participants With B-cell Lymphoma

Mantle Cell Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | CD19 Positive

United States
Progenity, Inc.

Unknown

Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women

Hypertension | Renal Insufficiency | Thrombocytopenia | Headache | Pre-Eclampsia | Pulmonary Edema | Visual Impairment | Impaired Liver Function | Proteinuria in Pregnancy

United States
Redwood Dermatology Sciences
Ultragenyx Pharmaceutical Inc

Completed

Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic Rickets

Pain, Chronic | Hypophosphatemia | Hypophosphatemic Rickets

United States
National Cancer Institute (NCI)

Completed

Phase I Study of Ipilimumab (Anti-CTLA-4) in Children and Adolescents With Treatment-Resistant Cancer

Sarcoma | Lymphoma | Neuroblastoma | Wilm's Tumor

United States
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Completed

Dose-escalation Study of Oral Administration of S 55746 in Patients With Chronic Lymphocytic Leukaemia and B-Cell Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukaemia (CLL) | Multiple Myeloma (MM) | B-Cell Non-Hodgkin Lymphoma (NHL)

France, Australia, Germany, Korea, Republic of, United Kingdom, Hungary, Poland, Singapore
Indiana University

Completed

Iron Therapy for Autosomal Dominant Hypophosphatemic Rickets: A Pilot Project.

Autosomal Dominant Hypophosphatemic Rickets

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia

Anemia | Weight Loss | Thrombocytopenia | Fever | Chronic Lymphocytic Leukemia | Lymphadenopathy | Prolymphocytic Leukemia | Richter Syndrome | Cancer Fatigue | Recurrent Chronic Lymphocytic Leukemia | Lymphocytosis | Infectious Disorder | Night Sweats | Secondary Malignant Neoplasm

United States

Clinical Trials on Aggressive Systemic Mastocytosis

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