Clinical Trials on Alcohol-Related Disorders

Total 162890 results

Mayo Clinic
Genentech, Inc.

Terminated

PR3-AAV Resilient Remission or PRRR

Microscopic Polyangiitis | Granulomatosis With Polyangiitis | ANCA Associated Vasculitis

United States
Imperial College London
AstraZeneca

Enrolling by invitation

Explore the Efficacy and Mechanism of Action of Tezepelumab in Eosinophilic Granulomatosis With Polyangiitis (RACEMATE)

EGPA - Eosinophilic Granulomatosis With Polyangiitis

United Kingdom
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease)

COVID-19 | Acute Respiratory Distress Syndrome | Sars-CoV2

United States
SpringWorks Therapeutics, Inc.

Active, not recruiting

MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas (ReNeu)

Plexiform Neurofibroma | Neurofibromatosis Type 1 (NF1)

United States
Enlivex Therapeutics Ltd.

Terminated

A Phase 2b Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study, Evaluating Efficacy and Safety of Allocetra-OTS in Patients With Severe or Critical COVID-19 With Associated Acute Respiratory Distress Syndrome (ARDS)

Covid19

Israel
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasms | Atypical Chronic Myeloid Leukemia | Myelodysplastic/Myeloproliferative Overlapping Syndrome

United States
Institut Curie

Active, not recruiting

Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)

Neuroblastoma | Opsoclonus Myoclonus Syndrome

France, Austria, Italy, Spain, Sweden, Switzerland, United Kingdom
Bahçeşehir University
Tugtepe Pediatric Urology Clinic

Completed

Comparison of Transcutaneous Electrical Nerve Stimulation and Manual Therapy in Children With Cerebral Palsy

Cerebral Palsy | Neurogenic Bowel | Neurogenic Bladder | Bowel Dysfunction | Bladder Dysfunction

Turkey
University Hospital, Basel, Switzerland
Swiss Foundation for the Study of Muscular Diseases

Completed

Longitudinal Imaging in Patients With Large Vessel Vasculitis to Predict Further Disease Course

Giant Cell Arteritis | Large Vessel Giant Cell Arteriitis

Switzerland
National Human Genome Research Institute (NHGRI)

Completed

Living With Sickle Cell Disease in the COVID-19 Pandemic

Pain | Anxiety | Sickle Cell Disease | Health Care Utilization | Isolation

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Cycling in Preventing Colorectal Cancer in Participants With Lynch Syndrome

High-Frequency Microsatellite Instability | Mismatch Repair Gene Mutation | Mutation-Negative Lynch Syndrome | Mutation-Positive Lynch Syndrome

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
University of Sao Paulo; National University of Ireland, Galway, Ireland; Carlos...

Active, not recruiting

PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia (PRoVENT-COP)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome | Mechanical Ventilation Complication

Netherlands, Argentina, Brazil, Ireland, Spain
University Hospital, Angers

Completed

Comparison of Different PEEP Titration Strategies Using Electrical Impedance Tomography in Patients With ARDS (DELTA)

Acute Lung Injury | ARDS (Acute Respiratory Distress Syndrome) | Positive End Expiratory Pressure (PEEP) | Electrical Impedance Tomography (EIT)

France
Rush University Medical Center

Completed

Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS

Acute Respiratory Distress Syndrome | Corona Virus Infection | High Flow Nasal Cannula | Prone Positioning

United States
Blueprint Medicines Corporation
Analysis Group, Inc.

Completed

Retrospective Study Assessing the Effect of Avapritinib Versus Best Available Therapy in Patients With AdvSM

Mast Cell Leukemia | Aggressive Systemic Mastocytosis | Advanced Systemic Mastocytosis | Systemic Mastocytosis With an Associated Hematological Neoplasm

United States, Austria, Germany, Spain, United Kingdom
Central Hospital, Nancy, France

Completed

Efficacy of Infusions of MSC From Wharton Jelly in the SARS-Cov-2 (COVID-19) Related Acute Respiratory Distress Syndrome (MSC-COVID19)

COVID19 ARDS

France
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS) | Chronic Myeloid Leukemia (CML)

United States
Assistance Publique - Hôpitaux de Paris

Completed

FX06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia (FX-COVID)

Pneumonia | Covid19 | Ards

France
Bispebjerg Hospital

Completed

MRI for the Early Evaluation of Acute Intracerebral Hemorrhage

Brain Neoplasms | Cerebral Hemorrhage | Intracranial Arteriovenous Malformations | Intracranial Hemorrhage, Hypertensive

Denmark
Unity Health Toronto
Defence Research and Development Canada

Unknown

RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study

COVID | Ischemia Limb | Acute Respiratory Distress Syndrome | Acute Lung Injury | Corona Virus Infection
Hospital Sirio-Libanes
Hospital Israelita Albert Einstein; Ache Laboratorios Farmaceuticos S.A.; Hospital... and other collaborators

Terminated

COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III (CoDEX)

Coronavirus Infection | Pneumonia, Viral | Acute Respiratory Distress Syndrome

Brazil
Azienda USL Toscana Nord Ovest
Azienda Ospedaliero, Universitaria Pisana; Azienda Ospedaliera Universitaria... and other collaborators

Unknown

Ruxolitinib for the Treatment of Acute Respiratory Distress Syndrome in Patients With COVID-19 Infection (RESPIRE)

Severe Acute Respiratory Syndrome Coronavirus 2
Universitätsmedizin Mannheim

Unknown

Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease | Sarcoidosis | Pulmonary Healthy Controls | Non-specific Interstitial Pneumonia | Granulomatosis With Polyangiitis (Wegener's Disease)

Germany
University Hospital Schleswig-Holstein
University College, London; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Completed

Continuous Regional Analysis Device for Neonate Lung (CRADL)

Acute Respiratory Distress Syndrome | Infant Respiratory Distress Syndrome | Acute Bronchiolitis

Netherlands, Finland, Cyprus
Wills Eye
University of Medicine and Dentistry of New Jersey

Terminated

Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol

Sturge Weber Syndrome | Port-wine Mark

United States
Rigshospitalet, Denmark

Terminated

Lung and Systemic Inflammation in the Critically Ill Patient

Sepsis | Acute Respiratory Distress Syndrome (ARDS) | Systemic Inflammatory Response Syndrome (SIRS)

Denmark
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Germany, France, Belgium, Canada, Spain, Switzerland, United Kingdom
Indonesia University

Unknown

The Effect of β-Carotene, Vitamin D3 and Zinc on Hyaline Membrane Disease and Feeding Intolerance in Premature Neonates

Hyaline Membrane Disease | Necrotizing Enterocolitis of Newborn

Indonesia
Mononuclear Therapeutics Ltd.
Chinese University of Hong Kong; China Spinal Cord Injury Network

Unknown

Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia

Anemia, Neonatal | Hypoxic-Ischemic Encephalopathy | Hypoxia Neonatal | Cerebral Ischemia of Newborn

Hong Kong
Johann Wolfgang Goethe University Hospital

Unknown

Susceptibility to Infections, Tumor Risk and Liver Disease in Patients With Ataxia Telangiectasia

Ataxia Telangiectasia

Germany
First Affiliated Hospital Xi'an Jiaotong University
Xijing Hospital; Shaanxi Provincial People's Hospital; Second Affiliated Hospital... and other collaborators

Unknown

Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome

Cerebral Palsy | Intracranial Hemorrhages | Premature Infants | Periventricular Leukomalacia

China
NICHD Neonatal Research Network
Canadian Institutes of Health Research (CIHR); National Center for Research... and other collaborators

Terminated

Early Inhaled Nitric Oxide for Respiratory Failure in Newborns (Early iNO)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants (MgSO4)

Cerebral Palsy | Intracranial Hemorrhages | Infant, Small for Gestational Age | Infant, Premature | Leukomalacia, Periventricular | Infant, Low Birth Weight | Infant, Newborn

United States
Institute Of Cardiology & Internal Diseases, Kazakhstan
Merck Sharp & Dohme LLC; Synergy Research Group

Unknown

Open-Label Efficacy and Safety Study of the Elbasvir/ Grazoprevir Fixed Dose Combination Patients With Chronic HCV GT1b

Metabolic Syndrome | Fibrosis, Liver | Cirrhoses, Liver | Chronic Hepatitis C Genotype 1B

Kazakhstan
Colorado State University
National Institute for Biomedical Imaging and Bioengineering (NIBIB)

Completed

Electrical Impedance Imaging of Patients on Mechanical Ventilation

Pneumothorax | Emphysema | Hyperinflation | Acute Respiratory Distress Syndrome | Pulmonary Edema | Pleural Effusion | Atelectasis | Pulmonary Contusion

United States
Baylor College of Medicine
Novartis Pharmaceuticals

Withdrawn

Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)

Sturge Weber Syndrome

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Terminated

S9624 Ifosfamide in Treating Patients With Meningeal Tumors

Chondrosarcoma | Adult Rhabdomyosarcoma | Adult Fibrosarcoma | Adult Leiomyosarcoma | Adult Malignant Meningioma | Adult Brain Malignant Hemangiopericytoma

United States, Australia, Peru, Puerto Rico
University Hospital, Clermont-Ferrand

Completed

Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients

Septic Shock | Acute Respiratory Distress Syndrome | Acute Lung Injury | Severe Sepsis | Mechanical Ventilation

France
Canadian Immunodeficiency Research Collaborative
Pur Medical Corporation

Completed

Safety, Efficacy and Psychological Effects of Treating Antiretroviral Drug-Induced Facial Lipoatrophy With Bio-Alcamid

Human Immunodeficiency Virus | Facial Lipoatrophy

Canada
Clarassance, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS)

Bronchopulmonary Dysplasia | Respiratory Distress Syndrome in Premature Infant

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia

MELAS Syndrome | Lactic Acidosis | Mitochondrial Myopathy

United States
Bellus Health Inc
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy

Stroke | Neurologic Diseases, General

United States
VM Oncology, LLC

Recruiting

Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

Sarcoma | Cervical Cancer | Breast Cancer | Adenoid Cystic Carcinoma | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Thymic Carcinoma | Lung Cancer | Mesothelioma | Bladder Cancer | Head and Neck Carcinoma | Uterine Cancer | Any Solid Tumors Progressed After a Prior Immunotherapy

United States, Puerto Rico
Quadriga Biosciences, Inc.
Novotech (Australia) Pty Limited

Completed

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Melanoma | Sarcoma | Kidney Cancer | Cervical Cancer | Breast Cancer | Head and Neck Cancer | Astrocytoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Thymic Carcinoma | Lung Cancer | Prostate Cancer | Brain Cancer | Cholangiocarcinoma | Bladder Cancer | Liver Cancer | Brain Metastases | Tongue Cancer | Esophagus... and other conditions

Australia
Bark Technology LLP

Recruiting

Evaluation of the Effectiveness and Safety of Vibro-acoustic Pulmonary Therapy (VAPT) in Complex Therapy for Acute Respiratory Failure of Mixed Type I-II Stages in Comparison With Percussion Massage in Cardiac Surgical Patients in the Early Postoperative Period

Cardiac Surgical Patients (CABG,Mammary Coronary Bypass Surgery,Plastic and Replacement of Valves, Atrial Septal Defect,Ventricular Septal Defect)

Kazakhstan
PYC Therapeutics

Recruiting

Natural History of Autosomal Dominant Optic Atrophy (ADOA), Caused by OPA1 Mutation

Optic Atrophies, Hereditary | Autosomal Dominant Optic Atrophy | Optic Atrophy, Autosomal Dominant | Kjer Optic Atrophy

Australia
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Individual Nutrition Support in HBV-ACLF Patients at Nutrition Risk

Acute-On-Chronic Liver Failure | Malnutrition | Nutrition Support | Hepatitis B,Chronic

China
Universitair Ziekenhuis Brussel

Recruiting

Non-invasive Ventilation in Preterm Infants

Premature Birth | Respiratory Distress Syndrome | Ventilator Lung; Newborn

Belgium
Wuhan Union Hospital, China

Not yet recruiting

Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MV

Acute Respiratory Distress Syndrome | Right Ventricular Dysfunction | Transesophageal Echocardiography

China
Shanghai Zhongshan Hospital

Recruiting

Determine the Effects of Prone Positioning and NO in COVID-19 ARDS by EIT

COVID-19 | Respiratory Distress Syndrome, Adult

China

Clinical Trials on Alcohol-Related Disorders

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