Clinical Trials on Allogenic Bone Marrow Transplantation

Total 4349 results

Nantes University Hospital

Terminated

Bone Demineralization Lesions in the Injured Marrow: Efficacy and Tolerability of Administration Early and Repeated the Zoledronic Acid. Comparative Study, Prospective, Double-blind Controlled (DBMZol) (DBMZol)

Bone Demineralization Lesions in the Injured Marrow

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01)

Sepsis | Septic Shock | Hematologic Malignancy | Tumor | Allogeneic Stem Cell Transplantation
Massachusetts General Hospital
Washington University School of Medicine; Medical College of Wisconsin; Vanderbilt... and other collaborators

Recruiting

Ruxolitinib + Allogeneic Stem Cell Transplantation in AML

Acute Myeloid Leukemia | Allogeneic Stem Cell Transplantation | Acute Myeloid Leukemia in Remission

United States
PharmaEssentia

Not yet recruiting

Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Low-Risk Polycythemia Vera (PV)

Polycythemia Vera | Myeloproliferative Neoplasm
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia

Neutropenia | Pancytopenia | Aplastic Anemia | Severe Aplastic Anemia

United States
Northwell Health

Terminated

Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia (ACE-011-DBA)

Diamond Blackfan Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia

Diamond Blackfan Anemia

United States
Washington University School of Medicine

Recruiting

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

Hemoglobinopathies | Bone Marrow Failure Syndromes | Metabolic Disorders | Non-malignant Disorders | Severe Sickle Cell Disease | Immunologic Disorders

United States
Children's Hospital Medical Center, Cincinnati
FDA Office of Orphan Products Development

Completed

Oxandrolone for the Treatment of Bone Marrow Aplasia in Fanconi Anemia

Fanconi Anemia

United States
Federal Scientific Clinical Centre of Pediatric...

Unknown

L-leucine in Diamond Blackfan Anemia Patients

Diamond Blackfan Anemia

Russian Federation
Columbia University

Unknown

Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases

Severe Combined Immunodeficiency | Fanconi Anemia | Bone Marrow Failure | Osteopetrosis

United States
Izmir Bakircay University

Completed

The Effect of Music Therapy on Comfort, Pain and Anxiety

Hematological Malignancy | Bone Marrow Disease

Turkey
The First Affiliated Hospital of Soochow University

Recruiting

Venetoclax+Azacytidine+Modified BUCY Conditioning Regimen for Acute Lymphoblastic Leukemia Undergoing Allo-HSCT

Acute Lymphoblastic Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation

China
M.D. Anderson Cancer Center

Completed

Busulfan Plus Clofarabine Followed by Allogeneic Hematopoietic Stem Cell Transplantation

Lymphoma | Leukemia | Acute Lymphoblastic Leukemia | Allogeneic Haematopoietic Stem Cell Transplantation

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

Hemoglobinopathies | AML | MDS | Bone Marrow Failure | ALL | Inherited Metabolic Disorders | HLH | MPD Withou Myelofibrosis | NHL or HL

United States
Feinstein Institute for Medical Research
Diamond Blackfan Anemia Foundation, Inc.

Recruiting

Diamond Blackfan Anemia Registry (DBAR) (DBAR)

Anemia | Blood Disease

United States
Fondazione Italiana Sindromi Mielodisplastiche-ETS

Completed

Identification of Mechanism in the Erythroid Response in Patients With Myelodysplasia Undergoing Chelation Therapy (BIOFER12)

Myelofibrosis | Aplastic Anemia | Myelodysplasia

Italy
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia

Neutropenia | Pancytopenia | Aplastic Anemia | Severe Aplastic Anemia

United States
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of Exjade in the Treatment of Transfusion-dependent Iron Overload in Aplastic Anemia Patients

Aplastic Anemia

Russian Federation
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Desferasirox in Chinese Patients With Iron Overload and Aplastic Anemia

Iron Overload

China
Paul Szabolcs

Recruiting

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC (PRO-RIC)

Congenital Bone Marrow Failure Syndromes | Inflammatory Conditions | Primary Immunodeficiency (PID) | Inherited Metabolic Disorders (IMD) | Hereditary Anemias

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Study of the Selective GlyT1 Inhibitor Bitopertin for Steroid-Refractory Diamond-Blackfan Anemia

Steroid-refractory Diamond-Blackfan Anemia (DBA)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

A Study to Determine Whether Therapy With Daclizumab Will Benefit Patients With Bone Marrow Failure

Aplastic Anemia | Pure Red Cell Aplasia | Diamond Blackfan Anemia

United States
Vejle Hospital
Odense University Hospital

Completed

The Efficacy of Velcade on Bone Tissue During Myelomatosis (Bone Marrow Cancer)

Multiple Myeloma

Denmark
Children's Hospital Medical Center, Cincinnati
Hoxworth Blood Center

Terminated

CD34+ Stem Cell Infusion to Augment Graft Function

Bone Marrow Failure | Waning Donor Chimerism | Waning Immune Function | Primary Immunodeficiency Disease(s)

United States
Pr. Nicolas GIRERD

Recruiting

The Effect of Eplerenone on the Evolution of Vasculopathy in Renal Transplant Patients. (EVATRAN)

Kidney Transplantation for More Than One Year | Patients With a Kidney Transplantation on Cyclosporine

France
Charlotte Niemeyer, MD

Completed

Serial Analysis of Chimerism in Patients With Refractory Cytopenia (RC) Transplanted With Reduced Intensity Conditioning (RIC)

Myelodysplastic Syndrome (MDS) | Refractory Cytopenia of Childhood | Hematopoietic Stem Cell Transplantation (SCT) | Reduced Intensity Conditioning (RIC)

Germany
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Up-front Matched Unrelated Donor Transplantation in Pediatric Patients With Idiopathic Aplastic Anemia (UPFRONT-MUD)

Severe Aplastic Anemia | Idiopathic Aplastic Anemia | Moderate Aplastic Anemia Requiring Transfusions
National University Hospital, Singapore

Unknown

Study of Non-Myeloablative Haplo-identical Haematopoietic Stem Cell Transplantation in Patients With Haematological Malignancies or Acquired Aplastic Anaemia

Haematological Malignancies | Acquired Aplastic Anaemia

Singapore
Medical University of Vienna

Suspended

Treatment of Atraumatic Bone Marrow Edema With Denosumab and Teriparatide vs Placebo

Quality of Life | Bone Marrow Oedema Syndrome | High Turnover Bone Disease

Austria
Charite University, Berlin, Germany
University of Leipzig

Unknown

Haploidentical Transplantation With Early Adoptive Transfer of CD56+CD3- NK Cells

Acute Myeloid Leukemias | Advanced Hematological Malignancies | Indication for Allogeneic Stem Cell Transplantation | no HLA-identical Donor Available

Germany
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia

Recurrent Severe Aplastic Anemia | Refractory Severe Aplastic Anemia

United States
Northwestern University
National Cancer Institute (NCI)

Withdrawn

Siltuximab in Treating Patients With Primary, Post-Polycythemia Vera, or Post-Essential Thrombocythemia Myelofibrosis

Primary Myelofibrosis | Polycythemia Vera | Myelofibrosis | Thrombocytopenia
Centro di Riferimento Oncologico - Aviano

Recruiting

Study for Validation of Target Therapy in Multiple Myeloma Cells From Patients With miRNAs Released From B Cells, and Study of the Bone Marrow Tumor Microenvironment (Microenvironment of MM)

Multiple Myeloma

Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Ruxolitinib Adherence in Myelofibrosis and Polycythemia Vera (RAMP)

Adherence, Patient | Adherence, Treatment

Italy
Merck Sharp & Dohme LLC

Terminated

Phase IIa Vorinostat (MK0683, Suberoylanilide Hydroxamic Acid (SAHA)) Study in Lower Risk Myelodysplastic Syndromes (0683-064)

Myelodysplastic Syndromes | Blood Disease | Bone Marrow Disease
National Cancer Institute (NCI)

Completed

Needs Assessment for Individuals and Families Affected by Dyskeratosis Congenita (DC) and Related Telomere Biology Disorders (TBD)

Dyskeratosis Congenita | Telomere Biology Disorders

United States
Adrianna Vlachos, MD

Terminated

The Use of Trifluoperazine in Transfusion Dependent DBA (DBA)

Pure Red Cell Aplasia | Diamond Blackfan Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia

Anemia, Aplastic | Red-Cell Aplasia, Pure | Anemia, Diamond-Blackfan

United States
Shanghai General Hospital, Shanghai Jiao Tong University...

Recruiting

Comparative Study of BFC and BuCy Conditioning Regimen for Allo-PBSCT in Acute B-cell ALL

Allogeneic Hematopoietic Stem Cell Transplantation | Acute B Lymphoblastic Leukemia

China
Wyeth is now a wholly owned subsidiary of Pfizer
PETHEMA (Program for the Study and Treatment of Haematological Malignances)

Completed

Study Comparing Piperacillin-tazobactam Versus Piperacillin-tazobactam Plus Glycopeptide in Neutropenic Patients

Lymphoma | Leukemia | Stem Cell Transplantation | Myelodysplasia | Myeloma | Hematological Malignancy

Spain
Rigshospitalet, Denmark

Completed

Family Caregiver Ambassador Support for Family Caregivers of Patients With Hematological Disease

Neoplasms | Lymphoma | Hematologic Diseases | Leukemia, Myeloid | Multiple Myeloma | Bone Marrow Transplantation

Denmark
University of Maryland, Baltimore
Healogics

Withdrawn

Hyperbaric Oxygen Therapy for Hematopoietic Progenitor Cell Collection in Poor Mobilizers

Lymphoma | Multiple Myeloma | Bone Marrow Transplantation | Hematopoietic Stem Cells

United States
European Institute of Oncology

Recruiting

Total Body Irradiation Treatments for Patients Treated at European Institute of Oncology

Lymphoma | Leukemia | Aplastic Anemia | Leukemia, Acute | Leukemia, Chronic

Italy
Incyte Corporation

Completed

COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial

MPN (Myeloproliferative Neoplasms)

United States, Canada, Australia
Seoul National University Hospital
Ministry of Food and Drug Safety, Korea

Unknown

Pharmacokinetic Study of Fludarabine in Pediatric Hematopoietic Stem Cell Transplantation

Acute Leukemia | Severe Aplastic Anemia | Chronic Leukemia

Korea, Republic of
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

Severe Aplastic Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Retrospective Study of Patients With Severe Aplastic Anemia Who Developed High Risk Clonal Evolution With Chromosome 7 Abnormalities After Immunosuppressive Therapy

Severe Aplastic Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Danazol for Genetic Bone Marrow and Lung Disorders

Aplastic Anemia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate, Clofarabine, and Busulfan With Vorinostat in Treating Patients With Acute Leukemia in Remission or Relapse Undergoing Donor Stem Cell Transplant

Previously Treated Myelodysplastic Syndrome | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Acute Lymphoblastic Leukemia | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Allogeneic Hematopoietic Stem Cell Transplantation Recipient

United States

Clinical Trials on Allogenic Bone Marrow Transplantation

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