Clinical Trials on Alpha-1 Protease Inhibitor Deficiency
Total 427 results
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National Jewish HealthMedical University of South CarolinaUnknownAlpha 1-Antitrypsin DeficiencyUnited States
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Biocerna LLCCompletedAlpha 1-Antitrypsin DeficiencyUnited States
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Medical University of South CarolinaNational Center for Research Resources (NCRR); Alpha-1 FoundationCompletedAlpha-1 Antitrypsin DeficiencyUnited States
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Grifols Therapeutics LLCCompletedAlpha 1-Antitrypsin DeficiencyUnited States
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Grifols Therapeutics LLCCompletedAlpha 1-Antitrypsin DeficiencyUnited States, United Kingdom
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National Center for Research Resources (NCRR)University of PittsburghTerminatedAlpha 1-Antitrypsin DeficiencyUnited States
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Beam Therapeutics Inc.Not yet recruitingAlpha 1-Antitrypsin DeficiencyUnited Kingdom
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Vertex Pharmaceuticals IncorporatedActive, not recruitingAlpha-1 Antitrypsin DeficiencyUnited States, United Kingdom, Germany, Ireland
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Vertex Pharmaceuticals IncorporatedCompleted
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Vertex Pharmaceuticals IncorporatedCompleted
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Arrowhead PharmaceuticalsCompletedAlpha 1-Antitrypsin DeficiencyUnited States, Spain, Netherlands, Germany, Italy, Portugal
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Adverum Biotechnologies, Inc.Completed
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Vertex Pharmaceuticals IncorporatedTerminatedAlpha 1-Antitrypsin DeficiencyUnited States, Germany, Canada, Ireland
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Kamada, Ltd.CompletedAlpha-1 Antitrypsin DeficiencyUnited States
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Fondazione Salvatore MaugeriAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia; Grifols... and other collaboratorsCompletedAlpha-1 Antitrypsin Deficiency
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OctapharmaWithdrawn
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Arrowhead PharmaceuticalsWithdrawnAlpha-1 Antitrypsin DeficiencyIreland, Canada, Italy, Sweden
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Krystal Biotech, Inc.RecruitingAlpha 1-Antitrypsin DeficiencyUnited States
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Hospital Universitari Vall d'Hebron Research InstituteEuropean Respiratory SocietyRecruitingAlpha 1-Antitrypsin DeficiencySpain
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University of FloridaRecruitingAlpha-1 Antitrypsin DeficiencyUnited States
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Dicerna Pharmaceuticals, Inc., a Novo Nordisk companyActive, not recruitingAlpha 1-Antitrypsin DeficiencyUnited Kingdom, United States, Ireland, Belgium, New Zealand, Spain, Netherlands, Portugal, Canada, Australia, France, Austria, Germany, Sweden
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St. Louis UniversityBoston University; University College, London; University of Massachusetts, Worcester and other collaboratorsActive, not recruiting
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Arrowhead PharmaceuticalsCompleted
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Arrowhead PharmaceuticalsTerminatedAlpha-1 Antitrypsin DeficiencyAustralia, Netherlands, Germany, United Kingdom
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Kamada, Ltd.CompletedAlpha 1-Antitrypsin DeficiencyUnited States
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Alnylam PharmaceuticalsTerminatedAntitrypsin Deficiency Liver DiseaseUnited Kingdom
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Applied Genetic Technologies CorpNational Heart, Lung, and Blood Institute (NHLBI)CompletedAlpha-1 Antitrypsin DeficiencyUnited States, Ireland
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University of FloridaCompletedAlpha-1 Antitrypsin Deficiency | Liver Fibrosis | AATD | AAT DeficiencyUnited States
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Rambam Health Care CampusHadassah Medical Organization; Tel-Aviv Sourasky Medical Center; Soroka University...CompletedGVHD | Bone Marrow Transplant Failure | Alpha 1-AntitrypsinIsrael
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Arrowhead PharmaceuticalsActive, not recruitingAlpha 1-Antitrypsin DeficiencyAustria, Germany, United Kingdom
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Dicerna Pharmaceuticals, Inc.WithdrawnAlpha 1-Antitrypsin DeficiencyNew Zealand
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Mereo BioPharmaSyneos HealthCompletedEmphysema | Alpha 1-Antitrypsin Deficiency | COPDUnited Kingdom, Belgium, United States, Denmark, Canada, Sweden, Poland, Spain
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University of Massachusetts, WorcesterNational Heart, Lung, and Blood Institute (NHLBI); University of Florida; National... and other collaboratorsCompletedAlpha 1-Antitrypsin DeficiencyUnited States
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Adverum Biotechnologies, Inc.CompletedAlpha 1-Antitrypsin DeficiencyUnited States
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Inhibrx, Inc.CompletedAlpha-1 Antitrypsin Deficiency | AATDUnited States, New Zealand, United Kingdom
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Coram Clinical TrialsCompletedAlpha-1 Anti-trypsin DeficiencyUnited States
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National Institutes of Health Clinical Center (CC)CompletedHIV | Hypertriglyceridemia | Fenofibrate | Protease Inhibitors | GlucuronosyltransferaseUnited States
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University of Alabama at BirminghamNational Institutes of Health (NIH); Mereo BioPharmaCompletedEmphysema or COPD | Alpha-1 Antitrypsin Deficiency (AATD) | Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I MutationsUnited States
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Arbor Research Collaborative for HealthNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Active, not recruitingPortal Hypertension | Cholestasis | Liver Fibrosis | Biliary Atresia | Alagille Syndrome | Alpha1 Anti-Trypsin DeficiencyUnited States, Canada
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Washington University School of MedicineNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...CompletedEndoplasmic Reticulum Stress | HIV Related Insulin Resistance | Protease Inhibitor Related Insulin ResistanceUnited States
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University of FloridaRecruitingAlpha-1 Antitrypsin Deficiency | Cystic Fibrosis (CF) | AATD | AAT DeficiencyUnited States
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Bristol-Myers SquibbCompletedHIV Infections | Protease InhibitorUnited States
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Bristol-Myers SquibbCompleted
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Gerard TurinoCompletedEmphysema | Alpha 1-Antitrypsin DeficiencyUnited States, Canada
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Laboratoire français de Fractionnement et de BiotechnologiesCompletedAlpha 1-Antitrypsin Deficiency
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University of FloridaAlpha-1 Foundation; Brantly, Mark L., M.D.CompletedAlpha 1-Antitrypsin DeficiencyUnited States
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Medical University of South CarolinaCSL BehringCompletedSmoking | Emphysema | Alpha-1 Antitrypsin Deficiency | COPDUnited States
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University of Massachusetts, WorcesterNational Heart, Lung, and Blood Institute (NHLBI); University of Florida; National... and other collaboratorsCompletedAlpha 1-Antitrypsin DeficiencyUnited States
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Grifols Therapeutics LLCCompletedAlpha 1-Antitrypsin DeficiencyDenmark, Sweden, United Kingdom
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National Heart, Lung, and Blood Institute (NHLBI)CompletedLung Diseases, Obstructive | Emphysema | Alpha 1-Antitrypsin DeficiencyUnited States