Clinical Trials on Alpha-Gal Syndrome in Canada

Total 2091 results

Baxalta now part of Shire

Completed

GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study

Alpha1-antitrypsin Deficiency

United States, Canada
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype

Alpha1-Antitrypsin Deficiency

United States, Germany, Canada, Ireland, Sweden, United Kingdom
Takeda
Takeda Development Center Americas, Inc.

Recruiting

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Alpha1-Antitrypsin Deficiency

United States, Belgium, Switzerland, Canada, Australia, Germany, United Kingdom, Austria, France, Spain, Portugal, Italy, Poland, Brazil
CSL Behring

Completed

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Emphysema | Alpha 1-proteinase Inhibitor Deficiency

Australia, Canada, Czech Republic, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Terminated

Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency

Chronic Obstructive Pulmonary Disease | Alpha1-antitrypsin Deficiency

United States, Canada, Australia
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE) (FORCE)

Portal Hypertension | Cholestasis | Liver Fibrosis | Biliary Atresia | Alagille Syndrome | Alpha1 Anti-Trypsin Deficiency

United States, Canada
Arrowhead Pharmaceuticals

Withdrawn

Safety, Tolerability and Effect of ARC-AAT Injection on Circulating and Intrahepatic Alpha-1 Antitrypsin Levels

Alpha-1 Antitrypsin Deficiency

Ireland, Canada, Italy, Sweden
Ciusss de L'Est de l'Île de Montréal

Completed

Comparison of BIS Index Variations: Bolus Versus Infusion Ketamine, and Impact on the Anesthesia Gas Consumption (KETABIS)

Bolus Versus Infusion Ketamine, Anesthesia Gas Consumption

Canada
Agios Pharmaceuticals, Inc.

Active, not recruiting

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT) (ENERGIZE)

Non-Transfusion-dependent Alpha-Thalassemia | Non-Transfusion-dependent Beta-Thalassemia

Spain, Taiwan, Thailand, United Kingdom, Malaysia, United States, Netherlands, Bulgaria, Turkey, Italy, Canada, Brazil, France, United Arab Emirates, Denmark, Greece, Lebanon, Saudi Arabia
Agios Pharmaceuticals, Inc.

Active, not recruiting

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT) (ENERGIZE-T)

Transfusion-dependent Alpha-Thalassemia | Transfusion-dependent Beta-Thalassemia

Spain, Taiwan, Thailand, United States, France, Canada, Malaysia, Germany, Netherlands, Bulgaria, United Kingdom, Turkey, Italy, Greece, United Arab Emirates, Brazil, Denmark, Lebanon, Saudi Arabia
CSL Behring

Completed

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Emphysema | Alpha1-proteinase Inhibitor Deficiency

Australia, Russian Federation, United States, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden, Canada, Czech Republic
University Health Network, Toronto
Zogenix, Inc.

Not yet recruiting

Fenfluramine for Adult Dravet Patients

Dravet Syndrome | Dravet Syndrome, Intractable

Canada
Takeda

Recruiting

A Study of Teduglutide (Revestive®) in Participants With Short Bowel Syndrome (SBS) in Canada

Short Bowel Syndrome (SBS)

Canada
MY01 Inc.
McGill University Health Centre/Research Institute of the McGill University... and other collaborators

Completed

MY01 - An Aid for Diagnosing Acute Compartment Syndrome in Real Time

Acute Compartment Syndrome

Canada
Ottawa Hospital Research Institute

Completed

Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome

Complex Regional Pain Syndromes | Shoulder Hand Syndrome

Canada
Gerard Turino

Completed

Efficacy/Safety of HA Inhalation Solution for Hereditary Emphysema in Patients With Alpha-1 Antitrypsin Deficiency

Emphysema | Alpha 1-Antitrypsin Deficiency

United States, Canada
Grifols Therapeutics LLC

Enrolling by invitation

Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency (SPARTA-OLE)

Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency

United States, New Zealand, Denmark, Australia, Finland, Estonia, Canada, Poland, Russian Federation, Sweden, France
Sunnybrook Health Sciences Centre
Novartis

Terminated

Azacitidine Plus Deferasirox (ICL670) in Higher Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

Canada
University of Waterloo
Alcon Research

Completed

A Pilot Study on the Use of a Sensory Panel to Assess Comfort Between Three Different Contact Lenses (NAISMITH)

Dry Eye Syndromes

Canada
University Health Network, Toronto
Novartis

Completed

Study Comparing Simulect Plus Standard Immunosuppression to Standard Immunosuppression Alone for the Prevention of Acute Rejection and Bronchiolitis Obliterans in Lung Transplant

Emphysema | COPD | Alpha-1 Antitrypsan Deficiency

Canada
Kamada, Ltd.

Completed

International Study Evaluating the Safety and Efficacy of Inhaled, Human, Alpha-1 Antitrypsin (AAT) in Alpha-1 Antitrypsin Deficient Patients With Emphysema

Emphysema

United Kingdom, Canada, Denmark, Germany, Ireland, Netherlands, Sweden
CSL Limited

Completed

Effect of rHDL on Atherosclerosis - Safety and Efficacy: THE ERASE TRIAL

Acute Coronary Syndromes

Canada
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) (LOGIC)

Liver Diseases | Alpha 1-Antitrypsin Deficiency | Alagille Syndrome

United States, Canada
Lawson Health Research Institute

Completed

Long Term Outcomes of Pediatric Compartment Syndrome

Compartment Syndromes

Canada
Grifols Therapeutics LLC

Active, not recruiting

Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD) (SPARTA)

Pulmonary Emphysema in Alpha-1 PI Deficiency

United States, Australia, Denmark, New Zealand, Estonia, Poland, Russian Federation, Sweden, Brazil, Canada, France, Finland
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Active, not recruiting

A Study of Belcesiran in Patients With AATLD (ESTRELLA)

Alpha 1-Antitrypsin Deficiency

United Kingdom, United States, Ireland, Belgium, New Zealand, Spain, Netherlands, Portugal, Canada, Australia, France, Austria, Germany, Sweden
Allergan

Completed

Clinical Trial to Evaluate the Symptoms in Symptomatic Contact Lens Wearers Following Application of Intranasal Tear Neurostimulator Versus Control

Dry Eye Syndromes

Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Canadian Blood Services

Terminated

Outpatient Platelet Transfusions in Myelodysplastic Syndromes and Leukemia: The OPTIMAL Pilot (OPTIMAL)

Leukemia | Myelodysplastic Syndrome

Canada
Mereo BioPharma
Syneos Health

Completed

A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo. (ASTRAEUS)

Emphysema | Alpha 1-Antitrypsin Deficiency | COPD

United Kingdom, Belgium, United States, Denmark, Canada, Sweden, Poland, Spain
University of Alberta

Recruiting

Conditioning Electrical Stimulation to Improve Outcomes in Cubital Tunnel Syndrome

Electrical Stimulation | Cubital Tunnel Syndrome

Canada
McGill University Health Centre/Research Institute...
McGill University

Terminated

Safety and Efficacy Study of Ethosuximide for the Treatment of Complex Regional Pain Syndrome (CRPS)

Complex Regional Pain Syndromes

Canada
McMaster University
St. Joseph's Healthcare Hamilton

Recruiting

Treatment of Complex Regional Pain Syndrome

Complex Regional Pain Syndrome

Canada
Vertex Pharmaceuticals Incorporated

Terminated

Evaluation of the Efficacy and Safety of VX-814 in Subjects With the PiZZ Genotype

Alpha 1-Antitrypsin Deficiency

United States, Germany, Canada, Ireland
University of Calgary
Alberta Health services; 3M

Active, not recruiting

Peritoneal Vacuum Therapy to Reduce Inflammatory Response From Abdominal Sepsis/Injury (SAD)

Intra-abdominal Hypertension | Abdominal Compartment Syndrome

Canada
Ottawa Hospital Research Institute

Recruiting

Peripheral Nerve Injections for CRPS

Complex Regional Pain Syndromes

Canada
Tracy Cupido

Not yet recruiting

Feasibility Study of Combined Peripheral Nerve Block and Physiotherapy for CRPS

Complex Regional Pain Syndromes

Canada
Ottawa Hospital Research Institute

Suspended

ED-TBI Followed By Allogeneic Stem Cell Transplantation For The Treatment Of Refractory AML And Advanced MDS (ED-TBI)

Acute Leukemia | Myelodysplastic Syndrome

Canada
McMaster University
CBS

Recruiting

Revisiting the Universal Donor: Does Exposure to O Blood Products Affect Patient Outcomes? (UD)

Myelodysplastic Syndrome

Canada
Western University, Canada

Completed

Intra-abdominal Hypertension in Critically Ill Patients

Intra-Abdominal Hypertension | Abdominal Compartment Syndrome

Canada
Ciusss de L'Est de l'Île de Montréal

Completed

CARbon Impact of aNesthesic Gas (CARING)

Anesthesia | Gas; Inhalation

Canada
Sunnybrook Health Sciences Centre

Not yet recruiting

OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study (OURA MDS)

Myelodysplastic Syndromes | MDS

Canada
argenx

Recruiting

A Natural History Study in Participants With DOK7 Congenital Myasthenic Syndromes (CMS)

Congenital Myasthenic Syndrome

Spain, Italy, France, United States, Canada
Novartis Pharmaceuticals

Completed

The Safety and Efficacy of Canakinumab in Patients Aged 4 Years or Older Diagnosed With Cryopyrin-associated Periodic Syndromes (CAPS) in Canada

Cryopyrin Associated Periodic Syndrome

Canada
The Hospital for Sick Children

Enrolling by invitation

Li-Fraumeni Syndrome Imaging Study

Li-Fraumeni Syndrome

Canada
Queen's University
AstraZeneca

Completed

Comparison of Rosuvastatin and Atorvastatin in Patients With Acute Coronary Syndrome

Dyslipidemia | Acute Coronary Syndromes

Canada
University of Manitoba

Completed

Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy (KOSATA)

Obstructive Sleep Apnea Syndrome

Canada
Salem Anaesthesia Pain Clinic

Recruiting

Chronic Pelvic Pain in Females and Males

Inguinal Hernia | Piriformis Syndrome | Pelvic Pain Syndrome | Sacrococcygeal Disorder | Sacroiliac Disorder

Canada
McMaster University
St. Joseph's Healthcare Hamilton

Recruiting

Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease

Bronchiectasis | Chronic Obstructive Pulmonary Disease | Asthma | Emphysema | Pulmonary Fibrosis | Alpha 1-Antitrypsin Deficiency | Bronchopulmonary Dysplasia | Sarcoidosis, Pulmonary

Canada
MY01 Inc.
Nova Scotia Health Authority

Completed

Clinical Trial of a New Device for Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome

Compartment Syndrome Traumatic Lower Extremity | Compartment Syndrome Traumatic Upper Extremity

Canada
Sunnybrook Health Sciences Centre
Celgene

Completed

Efficacy Study of Revlimid® and Low Dose Continuously Administered Melphalan to Treat High Risk MDS (REMMYDYS)

Myelodysplastic Syndromes | Leukemia, Myelomonocytic, Chronic | Angiogenesis

Canada

Clinical Trials on Alpha-Gal Syndrome in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Malaysia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations