Clinical Trials on Alzheimer' Disease in United Kingdom

Total 147261 results

Ascentys Ltd

Not yet recruiting

Feasibility Study of Game Technology in the Early Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease (G:DATA)

Dementia Alzheimers

United Kingdom
Washington University School of Medicine
Hoffmann-La Roche; National Institute on Aging (NIA); Alzheimer's Association

Terminated

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia: A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, France, Spain, Ireland, Canada, Australia, Puerto Rico, United Kingdom
Washington University School of Medicine
Eli Lilly and Company; Hoffmann-La Roche; Avid Radiopharmaceuticals; National Institute... and other collaborators

Completed

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, France, Spain, Ireland, Australia, Puerto Rico, United Kingdom
University of North Carolina, Chapel Hill
National Institute on Aging (NIA)

Completed

Telephone-delivered Mindfulness Intervention for African American Dementia Caregivers

Alzheimer Dementia | Dementia Alzheimers | Caregiver

United States
Washington University School of Medicine
Eli Lilly and Company; Hoffmann-La Roche; Avid Radiopharmaceuticals; National Institute... and other collaborators

Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001 (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, Italy, Argentina, Australia, Colombia, France, Ireland, Mexico, Netherlands, Puerto Rico, Spain, United Kingdom, Brazil, Japan, Germany
Washington University School of Medicine
National Institute on Aging (NIA); Alzheimer's Association; Eisai Inc.; Accelerating...

Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, Italy, Argentina, Australia, Colombia, Netherlands, Puerto Rico, Spain, United Kingdom, France, Ireland, Mexico, Brazil, Japan, Germany
Massachusetts General Hospital
National Institutes of Health (NIH); National Institute on Aging (NIA)

Active, not recruiting

MASC: Reducing Stress for Caregivers (MASC)

Dementia Alzheimers | Alzheimer Disease and Related Dementias

United States
King's College London

Unknown

Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO-AD)

Moderate to Severe Alzheimer's Disease

United Kingdom
Medivation, Inc.
Pfizer

Terminated

A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease (CONTACT)

Moderate to Severe Alzheimer

Chile, United Kingdom
Alnylam Pharmaceuticals

Recruiting

A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD

Early-Onset Alzheimer Disease

United Kingdom, United States, Netherlands, Canada
University of North Carolina, Chapel Hill
National Institute on Aging (NIA)

Enrolling by invitation

The Nightlight Falls Prevention Study

Alzheimer Disease | Aging | Fall Injury | Dementia Alzheimers | Dementia of Alzheimer Type

United States
Washington University School of Medicine
Hoffmann-La Roche; Genentech, Inc.; National Institute on Aging (NIA); Alzheimer...

Suspended

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, Italy, France, Spain, Ireland, Argentina, Australia, Colombia, Germany, Mexico, Netherlands, Puerto Rico, United Kingdom
University of Aberdeen
NHS Grampian; Tenovus Scotland

Completed

Ageing Gut Brain Interactions

Dementia Alzheimers

United Kingdom
Novoic Limited

Recruiting

Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech - PAST Extension (AMYPRED-PAST)

Alzheimer Disease | Mild Cognitive Impairment | Prodromal Alzheimer's Disease | Alzheimer's Disease (Incl Subtypes) | Preclinical Alzheimer's Disease

United Kingdom
Novoic Limited

Completed

Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech (AMYPRED)

Alzheimer Disease | Mild Cognitive Impairment | Prodromal Alzheimer's Disease | Alzheimer's Disease (Incl Subtypes) | Preclinical Alzheimer's Disease

United Kingdom
University of Edinburgh
Keele University

Active, not recruiting

Dementia Risk Prediction Model: Development and Validation

Dementia Alzheimers

United Kingdom
Hoffmann-La Roche

Recruiting

Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease

Alzheimers Disease

Korea, Republic of, United States, Canada, Poland, Spain, Australia, Japan, Chile, United Kingdom
ACADIA Pharmaceuticals Inc.

Completed

A Study of the Safety and Efficacy of Pimavanserin in Patients With Alzheimer's Disease Psychosis

Alzheimer's Disease Psychosis

United Kingdom
Novoic Limited

Recruiting

Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech - FUTURE Extension (AMYPRED-FUTURE)

Alzheimer Disease | Mild Cognitive Impairment | Prodromal Alzheimer's Disease | Alzheimer's Disease (Incl Subtypes) | Preclinical Alzheimer's Disease

United Kingdom
Imperial College London

Active, not recruiting

Noradrenergic Add-on Therapy With Guanfacine (NorAD)

Alzheimer Disease

United Kingdom
GlaxoSmithKline

Terminated

A Positron Emission Tomography (PET) Study to Investigate the Brain Biodistribution of 18F GSK2647544 in Healthy Subjects to Determine Its Ability to Cross the Blood-brain-barrier.

Alzheimer's Disease

United Kingdom
Imperial College London
GlaxoSmithKline

Terminated

I2PETPG - Imidazoline2 Binding Sites in a Group of Participants Diagnosed With AD (I2PETPG)

Alzheimer Disease

United Kingdom
University of Aberdeen
NHS Grampian

Recruiting

Detecting Early Alzheimer's Using MR (DREAMER)

Alzheimer Disease

United Kingdom
Asceneuron S.A.

Completed

Positron Emission Tomography Study in Healthy Subjects to Determine the Relationship Between Plasma Concentration and Brain Target Occupancy of ASN51

Alzheimer Disease

United Kingdom
University of Manchester
GlaxoSmithKline

Terminated

Pilot PET Study of Regional Cerebral Protein Synthesis in Alzheimer's

Alzheimer Disease

United Kingdom
Imperial College London
King's College Hospital NHS Trust; University of Oxford; University of Southampton and other collaborators

Unknown

Evaluating Liraglutide in Alzheimer's Disease (ELAD)

Alzheimer's Disease

United Kingdom
Heptares Therapeutics Limited
P1vital Limited

Completed

Phase 1 Study Investigating Effects of HTL0009936 on Cognition and BOLD fMRI Signals in Healthy Elderly Subjects

Alzheimer's Disease

United Kingdom
AstraZeneca

Terminated

Pharmacokinetic Interaction Between AZD3480 and Donepezil

Alzheimer's Disease

United Kingdom
Avid Radiopharmaceuticals

Completed

The Feasibility of Florbetapir Quantitation

Alzheimers Disease

United States
University of East Anglia
Quadram Institute Bioscience

Recruiting

DIetary plAnt Extracts, Colonic MicrObes, and Apoe geNetics Interactions stuDy (DIAMOND)

Alzheimer Disease

United Kingdom
Alzheon Inc.
Quotient Clinical

Completed

Multiple Ascending Dose Study of ALZ-801

Alzheimer Disease

United Kingdom
GlaxoSmithKline

Completed

Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects

Alzheimer's Disease

United Kingdom
University of Southampton
Wyeth is now a wholly owned subsidiary of Pfizer; Hampshire Hospitals NHS Foundation...

Completed

Safety and Tolerability of Etanercept in Alzheimer's Disease (STEADI-09)

Alzheimer's Disease

United Kingdom
GlaxoSmithKline

Terminated

Effects Of Rosiglitazone (Extended Release Tablets) On Cerebral Glucose Utilisation And Cognition Alzheimers Disease

Alzheimer's Disease

United Kingdom
Hoffmann-La Roche

Completed

A Single Ascending Dose Study to Investigate the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Intravenously Administered RO7126209 in Healthy Participants

Alzheimers Disease

United States
Elizabeth K Rhodus
National Institute on Aging (NIA)

Recruiting

Person-Environment Fit for Persons With Dementia

Alzheimer Disease | Dementia Alzheimers

United States
Bijan Najafi, PhD
BioSensics

Recruiting

Care Coordination System for People With Dementia

Dementia | Alzheimer Disease | Dementia Alzheimers

United States
Heptares Therapeutics Limited

Completed

Phase I, Healthy Subject, Safety, Tolerability and Pharmacokinetic Study of an M1 Agonist to Treat Cognitive Impairment

Alzheimer's Disease

United Kingdom
AstraZeneca

Terminated

Study of Uptake, Break Down and Elimination of an Investigational Drug in Healthy Volunteers (MB)

Alzheimer's Disease

United Kingdom
Phytopharm

Completed

Safety and Effect on Memory of PYM50028 in Mild Alzheimer's Disease

Alzheimer's Disease

United Kingdom
Avid Radiopharmaceuticals

Terminated

A Phase 0, Open Label, Multi-Center, Exploratory and Safety Study of [F-18]T808 (T808)

Alzheimers Disease

United States
AstraZeneca

Completed

Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults

Alzheimer's Disease | Memory Impairment

United Kingdom
Hoffmann-La Roche

Terminated

A Study to Evaluate the Efficacy and Safety of Gantenerumab in Participants at Risk for or at the Earliest Stages of Alzheimer's Disease (AD) (SKYLINE)

Alzheimers Disease

United States, United Kingdom, Korea, Republic of, Poland, Canada, Australia, Argentina, Spain, Sweden, Italy
Brain Health Scotland Life Sciences Ltd

Recruiting

IONA Longitudinal Cohort Study (IONA LCS)

Dementia | Alzheimer Disease

United Kingdom
University of Aberdeen

Terminated

Discovering FFC-MRI Biomarkers of Alzheimer Disease

Alzheimer Disease

United Kingdom
GlaxoSmithKline

Terminated

GSK2647544 RD, DDI in Healthy Young and Elderly Volunteers

Alzheimer's Disease

United Kingdom
Heptares Therapeutics Limited
Quotient Clinical

Completed

Relative Bioavailability Study in Healthy Subjects to Evaluate the Pharmacokinetics of HTL0009936 After One Dose of Prototype Formulation

Alzheimer's Disease

United Kingdom
Avid Radiopharmaceuticals

Terminated

A Phase 0, Open Label, Multi-center Exploratory and Safety Study of [F-18]T807

Alzheimers Disease | AD

United States
Cognito Therapeutics, Inc.

Recruiting

A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011) (Hope)

Cognitive Impairment | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | MCI | Dementia Alzheimers | Mild Dementia | Dementia of Alzheimer Type | Cognitive Impairment, Mild | Alzheimer Disease 1 | Dementia, Mild | Alzheimer... and other conditions

United States
South London and Maudsley NHS Foundation Trust

Enrolling by invitation

UK Based Remote Brain Health Clinic (BHC) for Patients With Mild Cognitive Impairment (MCI) (BHC)

Mild Cognitive Impairment | Mild Cognitive Impairment Due to Alzheimer's Disease

United Kingdom

Clinical Trials on Alzheimer' Disease in United Kingdom

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