Clinical Trials on Amyloid Neuropathies in Czechia

Total 137 results

AGC Biologics S.p.A.
Horizon 2020 - European Commission

Terminated

Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma

Acute Myeloid Leukemia | Multiple Myeloma

Italy, Czechia
TC Biopharm

Completed

Ex-vivo Expanded γδ T-lymphocytes (OmnImmune®) in Patients With Acute Myeloid Leukaemia (AML)

Acute Myeloid Leukemia

Czechia
Alnylam Pharmaceuticals

Active, not recruiting

APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Australia, Brazil, Bulgaria, France, Italy, Japan, Mexico, Netherlands, Taiwan, United Kingdom, Belgium, Czechia, Denmark, New Zealand, Sweden, Korea, Republic of, Argentina, Chile, Hong Kong, Portugal
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Vernalis (R&D) Ltd

Completed

Study of the Safety, Tolerability and Efficacy of V3381 in Patients With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

United States, United Kingdom, Canada, Czech Republic
Astellas Pharma Europe B.V.

Completed

A Study Into Pain Relief Given by ASP8477 for Peripheral Neuropathic Pain (Either Post-herpetic Neuralgia or Painful Diabetic Peripheral Neuropathy) and Its Safety (MOBILE)

Neuropathic Pain | Post-Herpetic Neuralgia (PHN) | Painful Diabetic Peripheral Neuropathy (PDPN)

Czechia, Germany, Poland, United Kingdom
Institute for Clinical and Experimental Medicine
Motol University Hospital; General University Hospital in Prague

Completed

Stimulation TcPO2 Test in the PAD Diagnosis in Diabetic Foot (stimTcPO2)

Peripheral Arterial Disease

Czechia
St. Anna Kinderkrebsforschung

Completed

Allogeneic Stem Cell Transplantation for Children With CML

Chronic Myeloid Leukemia

Austria, Czechia, Italy
Mgr. Eliška Vrátná
Vladimíra Fejfarová, MD, PhD; prof. Ing. Václav Bunc, CSc

Unknown

Musculoskeletal Changes After Physiotherapeutic Intervention in Podiatric Subjects (BIONEDIAN)

Prevention of Diabetic Foot

Czechia
Masaryk University

Withdrawn

The Effect of Gabapentin Used as a Preemptive to the Emergence and Development Chronic Neuropathic Pain in Patients After Spinal Cord Trauma (GabaNeuBol)

Spinal Cord Injuries | Chronic Pain Due to Trauma

Czechia
Masaryk University

Active, not recruiting

Efficacy and Safety of TKIs' Withdrawal After a Two-step Dose Reduction in Patients With Chronic Myeloid Leukemia (HALF)

Chronic Myeloid Leukemia, Chronic Phase | Withdrawal;Drug

Czechia
BioLineRx, Ltd.
Genentech, Inc.

Terminated

A Phase Ib/II, Multicenter, Single Arm, Open-Label Study, To Evaluate the Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab Combination for Maintenance Treatment in Subjects With Acute Myeloid Leukemia Who Are 60 Years or Older - The BATTLE Study

Acute Myeloid Leukemia

Israel, Spain, United States, Czechia, Poland, Slovakia
University of Jena

Recruiting

European CML Blast Crisis Register (BlastCrisis)

Chronic Myeloid Leukemia in Myeloid Blast Crisis

Germany, Czechia, Russian Federation, Ukraine
Biogen

Completed

Crossover Study of CNV1014802 in Subjects With Neuropathic Pain From Lumbosacral Radiculopathy

Lumbosacral Radiculopathy

Sweden, France, Czechia, Denmark
Algiax Pharmaceuticals GmbH
FGK Clinical Research GmbH

Recruiting

AP-325 in Subjects With Peripheral Post-surgical Neuropathic Pain

Peripheral Post-surgical Neuropathic Pain

Czechia, Germany, Spain, Belgium, France
Akinion Pharmaceuticals AB

Terminated

Safety Study of AKN-028 in Patients With Acute Myelogenous Leukemia

Acute Myeloid Leukemia

Sweden, Poland, Czech Republic, United Kingdom
Biogen

Terminated

Extension Study to Evaluate the Long-Term Safety, Tolerability, and Maintenance of Effect of BIIB074 (RELAY-1 Extend)

Neuropathic Pain From Lumbosacral Radiculopathy

Spain, United Kingdom, Slovakia, Austria, Belgium, Bulgaria, Czechia, France, Georgia, Italy, Latvia, Romania, Serbia, Estonia
Novo Nordisk A/S

Recruiting

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

United States, Netherlands, Germany, Canada, Czechia, France, Italy, Portugal, Spain
Olympus Biotech Corporation

Completed

The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Southern Europe The TRANS-South Study (TRANS-South)

Diabetic Foot Ulcer of Neuropathic Origin

France, Italy, Hungary, Czech Republic
Hannover Medical School

Completed

Allogenic Stem Cell Transplantation for Children, Adolescents and Young Adults With Relapsed or Refractory AML

Acute Myeloid Leukemia (AML)

Austria, Czechia, Germany
Astellas Pharma Inc

Completed

Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch (LIFT)

or Peripheral Nerve Injury (PNI) | Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN)

Belgium, Czechia, Denmark, Ireland, Norway, Slovakia, United Kingdom
Novo Nordisk A/S

Active, not recruiting

A Research Study to Look at How a New Medicine Called NNC6019-0001 Works and How Safe it is for People Who Have Heart Disease Due to Transthyretin (TTR) Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

United States, Netherlands, Spain, Portugal, Canada, Czechia, France, Germany, Italy, Japan
Bayer

Completed

A Study to Learn How Safe BAY2395840 is and How Well it Works in Participants Who Have Diabetic Nerve Pain

Diabetes Mellitus | Neuropathic Pain Associated With Diabetic Peripheral Neuropathy | Peripheral Neuropathic Pain

Hungary, Spain, Germany, Czechia, Slovakia, United Kingdom
Aziende Chimiche Riunite Angelini Francesco S.p.A
Chiltern International Inc.

Completed

Trazodone in Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

Czechia, Hungary, Poland
Swedish Orphan Biovitrum

Completed

Efficacy and Tolerability of Novel A2A Agonist in Treatment of Diabetic Neuropathic Pain

Diabetic Neuropathic Pain

Czech Republic, Germany, South Africa
Laboratoires URGO

Unknown

Assessment of the Efficacy and Safety of a New Medical Device in the Local Treatment of Diabetic Foot Ulcers (DISCOVERY)

Diabetic Foot Ulcer

Czechia, France, Italy, Poland, Spain, United Kingdom
Astellas Pharma s.r.o.

Completed

A Study of Efficacy and Safety of Qutenza in Patients With Post-operative Peripheral Neuropathic Pain

Post-operative Peripheral Neuropathic Pain

Czech Republic
Aptabio Therapeutics, Inc.

Completed

Safety, Tolerability and Renal Effects of APX-115 in Subjects With Type 2 Diabetes and Nephropathy

Diabetes Mellitus, Type 2 | Diabetic Nephropathies | Nephropathy, Diabetic

Bulgaria, Czechia, Hungary, Serbia
European Society for Blood and Marrow Transplantation
Novartis

Completed

Non Interventional Study on Iron Toxicity After First Allo-transplant in MDS/CMML

MDS | CMML

Germany, Belgium, Czechia
Universitätsklinikum Hamburg-Eppendorf
Clinical Trial Center North (CTC North GmbH & Co. KG); DKMS Stiftung Leben...

Recruiting

Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia

Myelodysplastic Syndromes | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission

Germany, Spain, Italy, Austria, Czechia, Finland, Russian Federation
Sanofi

Completed

Efficacy and Safety Study of Ataciguat Versus Placebo in Patients With Neuropathic Pain (SERENEATI)

Pain

Romania, Czech Republic, Austria
Bayer

Terminated

A 2-part Trial to Learn More About How BAY1817080 Works, How Safe it is, and What the Right Dose is for Participants With Diabetic Neuropathic Pain

Neuropathic Pain Associated With Diabetic Peripheral Neuropathy

Germany, Denmark, France, Poland, Finland, Czechia, Hungary, Norway, Slovakia, Sweden
AbbVie (prior sponsor, Abbott)

Completed

A Safety and Efficacy Study in Subjects With Diabetic Neuropathic Pain

Diabetic Neuropathic Pain

United States, Czech Republic, France, Germany, Italy, Spain, United Kingdom
Novartis Pharmaceuticals

Recruiting

A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML

FLT3-mutated Acute Myeloid Leukemia

Korea, Republic of, Germany, Italy, Turkey, Czechia, Jordan, Slovenia, Austria, Poland, Japan, Russian Federation, United States, Greece
AbbVie (prior sponsor, Abbott)

Completed

A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain

Diabetic Neuropathic Pain

United States, Czech Republic, France, Germany, Mexico
Eidos Therapeutics, a BridgeBio company

Active, not recruiting

Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

Amyloid Cardiomyopathy, Transthyretin-Related

United States, Spain, Australia, Canada, Italy, Netherlands, Ireland, New Zealand, Belgium, Israel, Greece, Korea, Republic of, Czechia, Brazil, Denmark, Portugal, United Kingdom
Technische Universität Dresden
Masaryk University; University Hospital Dresden

Completed

Comparison Between Two Dose Levels of Daunorubicin and Between One vs. Two Induction Cycles for Adult Patients With AML (DaunoDouble)

Leukemia, Myelocytic, Acute

Germany, Czechia
Kronos Bio

Terminated

Entospletinib Plus Intensive Induction/Consolidation Chemotherapy in Newly Diagnosed NPM1-mutated AML

Nucleophosmin 1-mutated Acute Myeloid Leukemia

Israel, Spain, France, United States, Czechia, Hungary, Korea, Republic of, Germany, Italy, Poland, Brazil, Canada
Pfizer

Completed

Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMML

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome

Spain, Canada, Austria, Czechia, France, Hungary, Italy, Japan, Mexico, Poland, United Kingdom
Grünenthal GmbH

Terminated

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking WHO Step III Analgesics But Showing a Lack of Tolerability

Pain | Low Back Pain | Chronic Pain | Neuropathic Pain | Nociceptive Pain

Belgium, Czechia, France, Germany, Netherlands, Poland, Spain, Switzerland
INRESA Pharma
RCTs

Completed

The Sorbact® Antimicrobial Dressing in the Holistic Wound Management Of Diabetic Foot ulCers (Phase III Study) (ADHOC)

Foot Ulcer, Diabetic

France, Czechia, Poland
Aposcience AG
FGK Clinical Research GmbH

Completed

A Study to Evaluate Safety and Efficacy of APO-2 at Three Different Doses in Patients With Diabetic Foot Ulcer

Diabetic Foot Ulcer (DFU)

Austria, Czechia, Germany, Poland
Alexion Pharmaceuticals, Inc.

Recruiting

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM (DepleTTR-CM)

Transthyretin Amyloid Cardiomyopathy

United States, Spain, United Kingdom, Norway, Israel, Korea, Republic of, Belgium, France, Germany, Italy, Japan, China, Australia, Argentina, Austria, Taiwan, Switzerland, Canada, Sweden, Poland, Denmark, Turkey, Brazil, Netherlands, G... and more
Ionis Pharmaceuticals, Inc.

Active, not recruiting

CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

United States, Australia, Spain, Canada, Germany, Japan, Italy, Israel, Argentina, France, Portugal, Austria, Brazil, Greece, United Kingdom, Czechia, Sweden, Belgium, Denmark, Poland, Puerto Rico
Poitiers University Hospital
University Medical Center Groningen; Imperial College London; University of Liege and other collaborators

Recruiting

International Chronic Myeloid Leukemia Pediatric Study (ICMLPed)

Chronic Myeloid Leukemia

Denmark, China, Germany, Australia, Belgium, Brazil, Chile, Croatia, Czechia, France, Greece, Japan, Lebanon, Poland, Spain, Turkey, Austria, Belarus, Netherlands, Slovakia
medac GmbH
Syneos Health; Celerion

Completed

Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies

Myelodysplastic Syndromes (MDS) | Acute Lymphoblastic Leukaemias (ALL) | Acute Myeloid Leukaemias (AML) | Juvenile Myelomonocytic Leukaemias (JMML)

Germany, United Kingdom, Italy, Austria, Czechia, Poland
EUROSPK Study Group
Wyeth is now a wholly owned subsidiary of Pfizer; Hoffmann-La Roche; Genzyme,... and other collaborators

Completed

European Trial of Immunosuppression in SPK Tx

Diabetes Mellitus, Type 1 | Diabetic Nephropathy

Belgium, Israel, Germany, Austria, Czechia, Spain, Switzerland
Novartis Pharmaceuticals

Completed

Safety, Tolerability and Efficacy of Nidufexor in Patients With Diabetic Nephropathy

Diabetic Nephropathy

Czechia, Lebanon, United States, Argentina, Germany, Jordan, Turkey
Biogen

Completed

Study to Evaluate the Efficacy and Safety of BIIB074 in Neuropathic Pain From Lumbosacral Radiculopathy (RELAY-1)

Lumbosacral Radiculopathy

Spain, United Kingdom, Austria, Belgium, Bulgaria, Czechia, France, Georgia, Italy, Latvia, Netherlands, Romania, Serbia, Slovakia
Associazione Italiana Ematologia Oncologia Pediatrica

Recruiting

Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia

Acute Promyelocytic Leukemia

Belgium, Netherlands, Czechia, Denmark, France, Germany, Ireland, Israel, Italy, Portugal, Spain, Sweden

Clinical Trials on Amyloid Neuropathies in Czechia

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