Clinical Trials on Antibody-secreting Cells in Germany

Total 2292 results

University of Erlangen-Nürnberg Medical School

Recruiting

De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck (DIREKHT2)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of the Hypopharynx

Germany
Novartis Pharmaceuticals

Terminated

Study of the Efficacy and Safety of Pasireotide s.c. +/- Cabergoline in Patients With Cushing's Disease

Cushings Disease

Italy, Belgium, India, Netherlands, Argentina, Germany, Turkey, Brazil, Spain, Hungary, Malaysia, Mexico, Greece, United States, Colombia, France
TME Pharma AG

Completed

NOX-A12 Multiple Ascending Dose Study in Healthy Volunteers (SNOXA12C101)

Hematopoietic Stem Cell Transplantation

Germany
Technische Universität Dresden
German Cancer Research Center

Recruiting

A Phase I Trial to Establish the Safety and Maximum Tolerated Dose of High-affinity Autologous BCMA-targeting Chimeric Antigen Receptor (CAR) T-cells in Patients With Relapsed and Refractory B-cell Malignancies (CARLOTTA01)

Neoplasms | Multiple Myeloma in Relapse | Multiple Myeloma, Refractory | Relapsed Diffuse Large B-cell Lymphoma (DLBCL) | Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Germany
Jurgen Barth
Sponsor GmbH

Active, not recruiting

Significance of Duration of Maintenance Therapy With Rituximab in Non-Hodgkin Lymphomas (MAINTAIN)

Non-Hodgkin's Lymphoma | Lymphocytic Lymphoma | Marginal Zone Lymphomas | Follicular Lymphomas | Immunocytomas | Mantle-Cell Lymphomas

Germany
Universitätsklinikum Hamburg-Eppendorf

Completed

Circulating Tumor Cells as a Biomarker for Preoperative Prognostic Staging in Patients With Esophageal Cancer

Resectable Esophageal Cancer

Germany
University Hospital Tuebingen

Unknown

Pipeline Integrating Gut Metagenome Data, Host Immunogenetic Characteristics and Clinical Gut Inflammatory Biomarkers (ImMiGeNe)

Stem Cell Transplantation

Germany
University Hospital Tuebingen

Unknown

Investigation of Desmoplastic Squamous Cell Carcinoma (DesmoPEK)

Squamous Cell Carcinoma of the Skin

Germany
AIO-Studien-gGmbH
Bristol-Myers Squibb

Completed

A Randomized Phase II Study on the Optimization of Immunotherapy in Squamous Carcinoma of the Head and Neck (OPTIM)

Carcinoma, Squamous Cell of Head and Neck | Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Germany
Heinrich-Heine University, Duesseldorf

Unknown

Trial to Evaluate Progression Free Survival With Primary Retroperitoneal Lymph-node Dissection (pRPLND) Only in Patients With Seminomatous Testicular Germ Cell Tumors With Clinical Stage IIA/B (PRIMETEST)

Stage II A/B Seminomatous Germ Cell Tumors

Germany
University Hospital Tuebingen

Completed

Darbepoetin Alfa in Patients With "Poor Prognosis" Germ Cell Tumor Treated With High-Dose Chemotherapy (HD-VIP)

Dysgerminoma

Germany
Biofrontera Bioscience GmbH
Accovion GmbH

Completed

Safety and Efficacy Study for the Treatment of Non-Aggressive Basal Cell Carcinoma With Photodynamic Therapy

Basal Cell Carcinoma (BCC)

Germany
Rigel Pharmaceuticals

Enrolling by invitation

A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia

Warm Antibody Autoimmune Hemolytic Anemia

Spain, United States, Australia, Norway, Belarus, Germany, Netherlands, Belgium, Austria, Bulgaria, Czechia, France, Georgia, Italy, Russian Federation, Serbia, Ukraine, United Kingdom
Novartis Pharmaceuticals

Completed

An Open-label, Multi-center, Expanded Access Study of Pasireotide s.c. in Patients With Cushing's Disease. (SEASCAPE)

Cushing's Disease

United States, Germany, Korea, Republic of, Spain, Thailand, Lebanon, Romania, Greece, Brazil, Russian Federation, Czechia
Universitätsklinikum Hamburg-Eppendorf
Staburo GmbH; Deutsche José Carreras Leukämie-Stiftung

Unknown

Humor Therapy and Distress After Allogeneic Stem Cell Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation

Germany
Spirig Pharma Ltd.

Terminated

Efficacy and Safety Trial of Topical Resiquimod Gel (0.06%) in Patients With Nodular Basal Cell Carcinoma

Nodular Basal Cell Carcinoma

Germany, Switzerland
Heidelberg University

Unknown

Prospective Trial on Immunochemotherapy Plus Autologous Stem Cell Transplantation (SCT) and Allogenic SCT in Primary Mantle-Cell-Lymphoma (HD-MCL2003)

Mantle-Cell Lymphoma

Germany
German CLL Study Group
Genzyme, a Sanofi Company; University of Cologne

Completed

Combined Immunochemotherapy in Patients With T-Prolymphocytic Leukemia (T-PLL)

T-cell-prolymphocytic Leukemia

Germany
Hoffmann-La Roche

Completed

Observational Study to Determine the Effectiveness and Safety of Vismodegib (Erivedge®) in Participants With Locally Advanced Basal Cell Carcinoma (laBCC) (NIELS)

Carcinoma, Basal Cell

Germany
University of Göttingen
Nordic Lymphoma Group; German High-Grade Non-Hodgkin's Lymphoma Study Group

Unknown

Immunotherapy in Peripheral T Cell Lymphoma - the Role of Alemtuzumab in Addition to Dose Dense CHOP (A-CHOP-14)

Extranodal NK/T-cell Lymphoma | Peripheral T Cell Lymphoma, Unspecified | Angioimmunoblastic Lymphadenopathy

Germany
University of Hohenheim
Universität Tübingen

Completed

Oral Bioavailability and Bioactivity of Prenylflavonoids From Hops

Safety After Oral Intake | Pharmacokinetics After Oral Intake | Immune Cells Activity

Germany
TME Pharma AG
German Federal Ministry of Education and Research

Completed

NOX-A12 First-in-human (FIH) Study

Autologous Stem Cell Transplantation

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Eli Lilly and Company; Trium Analysis Online GmbH

Completed

Study With Paclitaxel +/- Ramucirumab in Patients With Squamous-cell Carcinoma of the Esophagus After Prior Therapy (RAMOS)

Squamous Cell Carcinoma of the Esophagus

Germany
University Hospital, Essen
Celgene

Completed

Lenalidomide, MTX, Ara-C and Rituximab in Relapsed Aggressive B-cell Lymphomas (LeMLAR)

B-cell Lymphoma

Germany
RECORDATI GROUP

Completed

Long Term Safety and Efficacy of Pasireotide s.c. in Patients With Cushing's Disease

Cushings Disease

Canada, France, Germany, Italy, United States, Israel, Romania, Colombia, Lebanon, Netherlands, United Kingdom
Goethe University

Completed

A Phase I, Dose-finding Study of BEZ235 in Adult Patients With Relapsed or Refractory Acute Leukemia

Acute Lymphoblastic Leukemia | Leukemia, Myelocytic, Acute | Chronic Myelogenous Leukemia With Crisis of Blast Cells

Germany
Miltenyi Biomedicine GmbH

Active, not recruiting

MB-CART20.1 Lymphoma

Non-Hodgkin's Lymphoma | Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma | B-cell Lymphoma Refractory | B-cell Lymphoma Recurrent

Germany
AIO-Studien-gGmbH
AstraZeneca

Terminated

Induction Therapy With Intercalated Tyrosine Kinase Inhibitor (TKI) and Chemotherapy in NSCLC With Activating Epidermal Growth Factor Receptor (EGFR) Mutation in Stages II-IIIB (NeoIntercal)

NSCLC | Non-squamous Non-small Cell Lung Cancer Stage II | Non-squamous Non-small Cell Lung Cancer Stage IIIA | Non-squamous Non-small Cell Lung Cancer Stage IIIB | Activating EGFR Mutation

Germany
University Hospital Tuebingen

Completed

Safety and Efficacy Study of Imiquimod 5% Cream Applied 3x Per Week for 8 or 12 Weeks in Low Risk Nodular Basal Cell Carcinoma

Carcinoma, Basal Cell

Germany
University Hospital Muenster

Completed

Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.

Sepsis | Pre-Eclampsia | Adiposity | Microscopic Polyangiitis | Granulomatosis With Polyangiitis | SIRS | Procalcitonin

Germany
AIO-Studien-gGmbH
Bristol-Myers Squibb

Completed

A Multicenter Open-label Phase II Trial to Evaluate Nivolumab and Ipilimumab for 2nd Line Therapy in Elderly Patients With Advanced Esophageal Squamous Cell Cancer (RAMONA)

Esophageal Cancer | Gastrooesophageal Cancer | Oesophageal Cancer | GastroEsophageal Cancer | Esophageal Cancers NOS | Oesophageal Cancer Metastatic | Esophageal Cancer Metastatic | Oesophageal Cancer Nos

Germany
Technische Universität Dresden
University Hospital Carl Gustav Carus; Cellex Gesellschaft für Zellgewinnung... and other collaborators

Completed

Plerixafor as a Salvage Regimen to Mobilize Allogeneic Stem Cells in Healthy Volunteers (MOBIL1)

Blood Stem Cell Harvest Failure

Germany
Technical University of Munich

Recruiting

Liquid Biopsy of Head and Neck Cancer Patients in Blood and Saliva (KOHACIN)

Head and Neck Squamous Cell Carcinoma

Germany
Heidelberg University
University Hospital Heidelberg

Terminated

TPF Followed by Cetuximab and IMRT Plus Carbon Ion Boost for Locally Advanced Head and Neck Tumors (TPF-C-HIT)

Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN): Oro-, Hypopharyngeal and Laryngeal Cancer

Germany
University Hospital Tuebingen

Unknown

Hypoxia-based Dose Escalation With Radiochemotherapy in Head and Neck Cancer

Squamous Cell Carcinoma of the Head and Neck

Germany
Johann Wolfgang Goethe University Hospital
Institut für Sportwissenschaften, Frankfurt; Fresenius University of Applied...

Completed

Physical Exercise Therapy in Pediatric Stem Cell Transplantation (BISON)

Hematopoetic Stem Cell Transplantation

Germany
CellSeed France S.A.R.L.
FGK Clinical Research GmbH

Withdrawn

Multicenter Study of CAOMECS Transplantation to Patients With Total Limbal Stem Cell Deficiency

Limbal Stem Cell Deficiency

Germany
Charite University, Berlin, Germany

Completed

InductionChemo-Radio-Antibody-Treatment (ICRAT)

Squamous Cell Carcinoma of the Neck | Squamous Cell Carcinoma of the Head

Germany
Heidelberg University

Unknown

EBUS-guided TBNA for Molecular Diagnostic of Mediastinal Lymph Nodes (LN)

Non Small Cell Lung Cancer

Germany
Pierre Fabre Pharma GmbH
DocCheck Medical Services GmbH

Completed

JAVLOR® Online Non-Interventional Trial (JONAS-1)

Transitional Cell Carcinoma

Germany
AIO-Studien-gGmbH
AstraZeneca

Recruiting

Radiation During Osimertinib Treatment: a Safety and Efficacy Cohort Study (ROSE)

NSCLC | EGFR Positive Non-small Cell Lung Cancer | Oligoprogression

Germany
AIO-Studien-gGmbH
Merck Sharp & Dohme LLC

Terminated

Study of Pembrolizumab Maintenance Following First-Line Platinum Based Chemotherapy in Patients With Metastatic Squamous - Non-Small Cell Lung Cancer (sNSCLC) (PRIMUS)

Metastatic Squamous Non-small Cell Lung Cancer

Germany
Hoffmann-La Roche

Completed

An Observational Study of Tarceva (Erlotinib) in First Line in Patients With Advanced EGFR Mutation-Positive Non-Small Cell Lung Cancer (GERTAC)

Non-Squamous Non-Small Cell Lung Cancer

Germany
Aktion Bronchialkarzinom e.V.

Completed

Randomized Phase III-Study in Stage IIIb and IV Non-Small-Cell Lung Cancer. Sequential Single-Agent vs. Double-Agent vs. Triple-Agent Therapy.

Non-Small-Cell Lung Carcinoma

Germany
AIO-Studien-gGmbH
Amgen; Assign Data Management and Biostatistics GmbH; Assign Clinical Research...

Terminated

Cisplatin and 5-FU +/- Panitumumab for Patients With Nonresectable,Advanced or Metastatic Esophageal Squamous Cell Cancer (POWER)

Esophageal Squamous Cell Cancer

Germany
SLK Kliniken Heilbronn GmbH

Recruiting

IVAC-RCC-001: A Personalized Neoantigen Vaccine as Add-on to Standard of Care Checkpoint Inhibitor in Advanced/Metastatic RCC Patients

Advanced Renal Cell Carcinoma

Germany
University Hospital Heidelberg
German Cancer Research Center; Heidelberg University

Active, not recruiting

Tumor-specific T Cells in Lung Cancer

Non-small Cell Lung Cancer

Germany
University Hospital Heidelberg
German Cancer Research Center; Heidelberg University

Completed

Immune Boost In Non-Small Cell Lung Cancer (RadImmune)

Non-small Cell Lung Cancer

Germany
Ulrich Keilholz
Charite University, Berlin, Germany; AstraZeneca

Completed

Feasibility & Efficacy of Durvalumab+Tremelimumab+RT and Durvalumab+RT in Non-resect. Locally Advanced HPVnegativ HNSCC (DURTRE-RAD)

Squamous Cell Carcinoma of the Head and Neck

Germany
AIO-Studien-gGmbH
Boehringer Ingelheim

Terminated

Maintaining ERBB Blockade in EGFR-mutated Lung Cancer (MARBLE)

Non-small-cell Lung Cancer With Somatic EGFR Mutations

Germany

Clinical Trials on Antibody-secreting Cells in Germany

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