Clinical Trials on Antiphospholipid Syndrome (APS)

Total 34756 results

Chelsea Therapeutics

Terminated

A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa Therapy

Parkinson's Disease | Pure Autonomic Failure | Dopamine Beta Hydroxylase Deficiency | Symptomatic Neurogenic Orthostatic Hypotension | Multiple Systems Atrophy

United States
University Of Perugia
University of Roma La Sapienza

Unknown

Botulinum A Toxin in Patients With Parkinson's Disease (Botox-PD)

Parkinson's Disease | Multiple System Atrophy | Detrusor Overactivity
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma and other conditions

United States
Mayo Clinic

Completed

Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade... and other conditions

United States
Yale University
National Cancer Institute (NCI)

Terminated

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

Kidney Cancer | Head and Neck Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Intraocular Melanoma | Melanoma (Skin) | Pheochromocytoma | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome | Neuroendocrine Carcinoma of the Skin | Childhood Langerhans Cell Histiocytosis

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation

Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Recurrent Hodgkin Lymphoma | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Recurrent Small Lymphocytic Lymphoma | Blastic Plasmacytoid Dendritic Cell Neoplasm | Prolymphocytic Leukemia and other conditions

United States
H. Lee Moffitt Cancer Center and Research Institute

Active, not recruiting

Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Hodgkin Lymphoma | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Lymphoplasmacytic Lymphoma | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Myeloproliferative Neoplasm | Relapsed Follicular Lymphoma | Relapsed T-Cell Lymphoma and other conditions

United States
Fairview University Medical Center

Unknown

Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Giant Cell Arteritis | Wegener's Granulomatosis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Purpura, Schoenlein-Henoch | Juvenile Rheumatoid Arthritis | Takayasu Arteritis | Pure Red Cell Aplasia | Graft Versus Host Disease | Anemia, Hemolytic, Autoimmune and other conditions

United States
Advice Pharma Group srl

Recruiting

KidneYou - Innovative Digital Therapy

Diabetes | Chronic Kidney Diseases | Tuberous Sclerosis | Albuminuria | Treatment Adherence | Arterial Hypertension | Treatment Adherence and Compliance | Nephronophthisis | Polycystic Kidney | Chronic Glomerulonephritis | Cystic Kidney Diseases | Cortical Cystic Disease | Cystic Diseases

Italy
National Cancer Institute (NCI)

Completed

MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade... and other conditions

United States
Hacettepe University

Recruiting

Exercise Capacity, Physical Fitness, and Physical Activity Levels in Children With CAH

Quality of Life | Congenital Adrenal Hyperplasia | Physical Activity | Exercise Capacity

Turkey
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Recruiting

Longitudinal Prospective Natural History Study of Retinopathy in Zellweger Spectrum Disorder (ZSDvision)

Zellweger Spectrum Disorder

Canada
University of Aarhus
Danish Cardiovascular Academy (DCA); Danish Diabetes Academy; Sygesikringen Danmark and other collaborators

Recruiting

Polyamine Treatment in Elderly Patients With Coronary Artery Disease (PolyCAD)

Myocardial Infarction | Cardiovascular Diseases | Quality of Life | Inflammation | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Cognitive Impairment | Metabolic Syndrome | Ischemic Heart Disease | Dietary Habits | Diastolic Dysfunction | Cognition Disorder | Hypertensive Heart Disease

Denmark
Assiut University

Recruiting

Association of Auditory Dysfunction With Retinal Ischemia in Behcet Disease

Behcet's Disease With Multisystem Involvement

Egypt
Conor Fearon
Queen's University

Recruiting

Unstructured Eye Tracking as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders

Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Parkinson's Disease and Parkinsonism

Ireland
Bionano Genomics
Columbia University; University of Iowa; Medical College of Wisconsin; Augusta... and other collaborators

Recruiting

Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort

Intellectual Disability | Autism Spectrum Disorder | Fragile X Syndrome | Developmental Disability | Congenital Anomaly | Facioscapulohumeral Muscular Dystrophy 1

United States
University of California, Los Angeles
Brigham and Women's Hospital; University of California, San Francisco; Antelope...

Recruiting

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients (NEXUS AP CT)

Hip Injuries | Pelvic Fracture | Bowel Disease | Aortic Dissection | Aortic Rupture | Abdominal Injury | Lumbar Spine Injury | Vascular System Injuries | Diaphragm Injury | Liver Injury | Spleen Injury | Renal Injury | Sacral Fracture | Genital Hemorrhage

United States
King's College London
King's College Hospital NHS Trust; Northern Care Alliance NHS Foundation Trust and other collaborators

Not yet recruiting

Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease (CRIPS)

Parkinson Disease | Impulsive Behavior | Gambling, Pathological | Hoarding Disorder | Caregiver Burnout | Dopamine Dysregulation Syndrome | Hypersexuality | Impulse Disorders | Eating, Binge | Compulsive Shopping
Center for Neurological Studies
Novo Nordisk A/S

Recruiting

Growth Hormone Replacement Therapy for Retried Professional Football Players

TBI (Traumatic Brain Injury) | Growth Hormone Deficiency | Hypopituitarism | Sport Injury | Concussion, Brain | Anterior Pituitary Hyposecretion Syndrome

United States
Inflammatix

Recruiting

HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis (SEPSIS-SHIELD)

Respiratory Tract Infections | Sepsis | Urinary Tract Infections | Intra-Abdominal Infections | Skin and Soft Tissue Infection | Suspected Meningitis/Encephalitis or Any Other Infection

United States, Greece
Hospital do Coracao
Hospital Israelita Albert Einstein; Hospital Moinhos de Vento; Hospital Sírio-Libanês and other collaborators

Completed

Daily Chlorexidine Bath for Health Care Associated Infection Prevention (CLEAN-IT)

Ventilator Associated Pneumonia | Health Care Associated Infection | Catheter-Associated Urinary Tract Infection | Central Line-associated Bloodstream Infection (CLABSI)

Brazil
Sheffield Teaching Hospitals NHS Foundation Trust
Society for Endocrinology; The Clinical Endocrinology Trust

Completed

Study of UK Adults With Congenital Adrenal Hyperplasia. (CaHASE)

Congenital Adrenal Hyperplasia

United Kingdom
Jose Soberon, MD

Terminated

Exparel as a Nerve Block for Severe Hand Pain

Scleroderma, Diffuse | Peripheral Vascular Disease | Raynaud Disease | CREST Syndrome

United States
Inflammatix

Withdrawn

Sepsis Prognosis and Diagnosis in the Emergency Department (SPEED)

Respiratory Tract Infections | Sepsis | Urinary Tract Infections | Intra-Abdominal Infections | Skin and Soft Tissue Infection | Suspected Meningitis/Encephalitis or Any Other Infection
Laminate Medical Technologies

Completed

VasQ External Support for Arteriovenous Fistula

Diabetes Mellitus | Renal Failure | ESRD | Aneurysm | Kidney Failure | Renal Disease | Arterio-Venous Fistula | Steal Syndrome

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Fertility Attitudes of Adolescents and Young Adults With Turner Syndrome and Their Parents/Guardians (The Fertility ConcepTS Study)

Fertility Perservation | Fertility

United States
Stanford University

Completed

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness

Obesity | Schizophrenia | Metabolic Syndrome | Bipolar Disorder | Weight Gain | Ketogenic Dieting | Psychotropic Agents Causing Adverse Effects in Therapeutic Use | Brain Metabolic Disorder

United States
National Institute on Deafness and Other Communication...

Terminated

Central Mechanisms in Speech Motor Control Studied With H215O PET

Healthy | Tourette Syndrome | Stuttering | Communication Disorder | Voice Disorder

United States
Pontificia Universidad Catolica de Chile
Ferring Pharmaceuticals

Completed

Severe Aortic Stenosis and Acquired Von Willebrand´s Disease: The Impact of Desmopressin in Valve-Replacement Surgery

Severe Aortic Stenosis | Acquired Von Willebrand Disease Secondary to Severe Aortic Stenosis | Heye´s Syndrome

Chile
Genzyme, a Sanofi Company

Completed

A Study of the Efficacy and Safety of Eliglustat Tartrate (Genz-112638) in Type 1 Gaucher Patients

Gaucher Disease, Type 1 | Cerebroside Lipidosis Syndrome | Glucocerebrosidase Deficiency Disease | Glucosylceramide Beta-Glucosidase Deficiency Disease | Gaucher Disease, Non-Neuronopathic Form

United States, Israel, Mexico, Russian Federation, Argentina, Italy
Hospital de Santa Maria, Portugal

Completed

Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term

Chorioamnionitis | Neonatal Meningitis | Puerperal Endometritis | Neonatal Early Onset Sepsis | Neonatal Pneumonia

Portugal
John Sievenpiper
Canadian Institutes of Health Research (CIHR); Canada Research Chairs Endowment... and other collaborators

Unknown

Meta-Analyses of the Effect of Vegetable Protein for Animal Protein on Cardiometabolic Risk

Hypertension | Obesity | Cardiovascular Disease | Diabetes | Overweight | Metabolic Syndrome | Dyslipidemia | Kidney Injury | Prediabetes | Gout | Dysglycemia | Kidney Disease | Non-alcoholic Fatty Liver Disease (NAFLD)

Canada
Assistance Publique - Hôpitaux de Paris

Completed

Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years (CORTAGE)

Vasculitis | Wegener's Granulomatosis | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa

France
CENTOGENE GmbH Rostock

Terminated

Biomarkers for Tuberous Sclerosis Complex (BioTuScCom) (TuScCom)

Lymphangioleiomyomatosis | Subependymal Giant Cell Astrocytoma | Facial Angiofibroma | Cortical Dysplasia | Renal Angiomyolipoma | Hypomelanotic Macules | Shagreen Patches | Ungual Fibromas | Cardiac Rhabdomyoma

Sri Lanka, Albania, Romania, Egypt, Pakistan, Georgia, India, Lithuania
Burke Medical Research Institute

Active, not recruiting

Home Based Tele-exercise for People With Chronic Neurological Impairments (Telex)

Stroke | Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Spinal Cord Injuries | Neurologic Disorder | Hemiplegia | Hemiparesis | Friedreich Ataxia | Trauma, Brain | Transverse Myelitis

United States
Massachusetts General Hospital

Not yet recruiting

CPAP in Patients With Severe Obesity After Anesthesia

Anesthesia Morbidity | Obesity, Abdominal | Ventilator Lung | Apnea, Obstructive Sleep | Atelectases, Postoperative Pulmonary
Shanghai General Hospital, Shanghai Jiao Tong University...

Not yet recruiting

Intensive Conditioning With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Myeloid Malignancies With Extramedullary Involvement

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myeloid Sarcoma | Myelodysplastic Neoplasm | Extramedullary Myeloid Tumor
Elsan

Not yet recruiting

Assessment of the Occurrence of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) in Women Suffering From Endometriosis (ENDOSAS)

Endometriosis | Obstructive Sleep Apnea-hypopnea
University of California, San Diego

Not yet recruiting

Obstructive Sleep Apnea Treatment in Serious Mental Illness

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Obstructive Sleep Apnea of Adult

United States
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

COVID-19 Vaccine Responses in PIDD Subjects

Common Variable Immunodeficiency | X-linked Agammaglobulinemia | Primary Immune Deficiency | Primary Antibody Deficiencies | CVID | XLA | Secondary Hypogammaglobulinemia

United States
Beijing Anzhen Hospital

Recruiting

Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep Apnea (VISION)

Coronary Artery Disease | Obstructive Sleep Apnea of Adult

China
Paul Szabolcs

Recruiting

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Sickle Cell Anemia | Diamond-blackfan Anemia | Beta-thalassemia Major

United States
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

A Nurse Case Management Intervention to Improve MDR-TB/HIV Co-Infection Outcomes

HIV | MDR-TB

South Africa
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisition

HIV Infections | Bacterial Vaginosis

South Africa
KalVista Pharmaceuticals, Ltd.

Terminated

A Trial to Evaluate the Efficacy and Safety of Different Doses of KVD824 for Prophylactic Treatment of HAE Type I or II (KVD824-201)

Angioedema, Hereditary, Types I and II

United States, Czechia, Germany, Hungary, Italy, North Macedonia, United Kingdom, Australia, Bulgaria, Canada, France, New Zealand, Puerto Rico
National Institutes of Health Clinical Center (CC)

Completed

PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects

Depression | HIV Infections | HIV-Associated Cognitive Motor Complex

United States
Ege University

Completed

Anxiety, Depression, and Quality of Life in Patients With Fibromyalgia During the Coronavirus Disease 2019 Pandemic

Fibromyalgia | Coronavirus Disease 2019 Pandemic

Turkey
Instituto de Ciências Biomédicas Abel Salazar

Completed

Evaluation of the Functional Impact of Adenotonsilectomy

Infections | Tonsillitis | Apnea, Obstructive | Tonsillar Hypertrophy | Respiratory Function Impaired | ENT Disorder

Portugal
University of British Columbia
MHE Coalition

Completed

The Health-Related Quality of Life in Patients With Hereditary Multiple Exostoses

Exostoses, Multiple Hereditary

Canada

Clinical Trials on Antiphospholipid Syndrome (APS)

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