Clinical Trials on Aortic Valve Disease

Total 379190 results

Medtronic Bakken Research Center

Completed

Post-Approval Study for the MOSAIC® Bioprostheses

Aortic Valve Stenosis and/or Insufficiency | Mitral Valve Stenosis and/or Insufficiency

Germany
Jewish General Hospital
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Duke University and other collaborators

Completed

Frailty Assessment Before Cardiac Surgery & Transcatheter Interventions

Aortic Stenosis | Fragility | Cardiac Valve Replacement Complication

United States, Canada, France
Protembis GmbH
MAXIS, LLC

Completed

The PROTEMBO SF Trial

Aortic Stenosis

Latvia, Ireland
French Cardiology Society
Institut National de la Santé Et de la Recherche Médicale, France; Centre National...

Active, not recruiting

Evaluation of Aortic Stiffness as a Prognostic Indicator of Aortic Dilatation in Patients With Bicuspid Aortic Valve by Multimodal Imaging (IRM-BAO)

Bicuspid Aortic Valve

France
Pan Xiangbin

Recruiting

A Prospective, Multicenter, Single-arm Study to Evaluate a Transcatheter Aortic Valve System Safety and Efficacy for the Treatment of Patients With Severe Aortic Stenosis

Severe Aortic Stenosis

China
Edwards Lifesciences

Recruiting

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR (PROGRESS)

Aortic Valve Stenosis | Aortic Stenosis, Calcific

United States, Switzerland, Australia, Japan, Canada, Netherlands
Colibri Heart Valve LLC

Recruiting

Colibri Transcatheter Aortic Heart Valve System Study

Severe Aortic Stenosis

France, United Kingdom
Medtronic Cardiovascular

Active, not recruiting

Safety & Efficacy Study of the Medtronic CoreValve® System-Treatment of Symptomatic Severe Aortic Stenosis With Significant Comorbidities in Extreme Risk Subjects Who Need Aortic Valve Replacement

Severe Aortic Stenosis

United States
Symetis SA

Completed

ACURATE™ Transapical Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2010-01) (TA-PILOT)

Aortic Symptomatic Stenosis

Germany
Medtronic Cardiovascular

Completed

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement

Severe Aortic Stenosis

United States
Medico's Hirata Inc.

Terminated

Safety and Efficacy of SYM-SV/DS-002 in Patients With Severe Aortic Stenosis

Severe Aortic Stenosis

Japan
Edwards Lifesciences

Active, not recruiting

EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis (EARLY TAVR)

Heart Diseases | Aortic Stenosis, Severe

United States, Canada
Maastricht University Medical Center

Unknown

Bicuspid Aortic Valve Stenosis and the Effect of vItamin K2 on Calciummetabolism on 18F-NaF PET/MRI (BASIK2)

Aortic Valve Stenosis | Bicuspid Aortic Valve

Netherlands
Royal Brompton & Harefield NHS Foundation Trust

Completed

Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans Catheter Aortic ValvE Replacement? (RECOVER-TAVR)

Aortic Stenosis

United Kingdom
Sahlgrenska University Hospital, Sweden

Completed

Effect of Steroids on Cerebral Inflammation and Neuronal Damage After Surgical Aortic Valve Replacement

Aortic Stenosis

Sweden
Seung-Jung Park
CardioVascular Research Foundation, Korea

Completed

The Asian Transcatheter Aortic Valve Replacement Registry (Asian TAVR)

Aortic Valve Stenosis | Aortic Diseases

Korea, Republic of, China, Taiwan, Japan, Singapore
Beth Israel Deaconess Medical Center

Recruiting

Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System (TAVR-HBE)

Aortic Stenosis | Heart Block | Transcatheter Aortic Valve Replacement

United States
Dokuz Eylul University

Completed

The Effect of Education and Follow-up Program in Patients Undergoing TAVI

Aortic Stenosis | Nursing Caries

Turkey
Avicena LLC

Withdrawn

Rapid Non-invasive Detection of Aortic Stenosis

Aortic Valve Disease | Heart Valve Diseases | Heart Murmurs

United States
Klinik für Kardiologie, Pneumologie und Angiologie

Completed

Virtual Reality Assisted Conscious Sedation During TAVI (TAVI_VR)

Pain | Anxiety | Severe Aortic Valve Stenosis

Germany
Edwards Lifesciences
Pacific Clinical Research Group

Completed

The SOLACE-AU Clinical Trial (SOLACE-AU)

Severe, Symptomatic Aortic Stenosis

Australia
Jung-min Ahn

Recruiting

Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement (RENOVATE)

Thromboembolism | AORTIC VALVE DISEASES

Korea, Republic of
Population Health Research Institute
Sunnybrook Health Sciences Centre; Hamilton Health Sciences Corporation; Southlake... and other collaborators

Active, not recruiting

Remote ECG Monitoring of TAVI Patients

Aortic Valve Stenosis | Cardiac Valve Disease

Canada
Karolinska University Hospital
Karolinska Institutet

Completed

Valve Leaflet Motion in Sutureless Bioprosthetic Aortic Valves

Aortic Valve Stenosis | Heart Valve Disease

Sweden
Second Affiliated Hospital, School of Medicine,...

Recruiting

Down Sizing Strategy (HANGZHOU Solution) vs Standard Sizing Strategy TAVR in Bicuspid Aortic Stenosis (Type 0) (TAILOR-TAVR)

Aortic Stenosis With Bicuspid Valve

China
Second Affiliated Hospital, School of Medicine,...
The First Affiliated Hospital of Nanchang University; Chinese PLA General Hospital and other collaborators

Recruiting

HANGZHOU Solution in Bicuspid AS Undergoing TAVR

Aortic Stenosis | Aortic Stenosis With Bicuspid Valve

China
Instituto Nacional de Cardiologia Ignacio Chavez

Completed

Evaluation of the Inflammatory Response in Post-operated Aortic Valve Replacement Patients.

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Calcification | Prosthetic Valve Malfunction

Mexico
University Hospital Inselspital, Berne

Terminated

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage (TAVI-LAAC)

Aortic Valve Disorder

Switzerland, Italy, Germany, Portugal
Baystate Medical Center
Springfield College

Completed

Physical and Functional Recovery From Cardiac Surgery in Hospitalized Patients: A Feasibility Pilot Study

Coronary Artery Disease | Aortic Valve Stenosis | Mitral Valve Insufficiency | Mitral Valve Stenosis | Aortic Valve Regurgitation | Coronary Artery Bypass Graft Triple Vessel

United States
Rhode Island Hospital

Recruiting

Assessment of Clinical Onset of IV Heparin in Interventional Cardiology and Cardiac Surgery (ACTPOC)

Transcatheter Aortic Valve Replacement | Cardiac Valve Annuloplasty

United States
Instituto Nacional de Cardiologia Ignacio Chavez

Completed

Analysis and Comparative Evaluation of Aortic Calcium by Computed Tomography and Histopathology in Patients With Aortic Stenosis

Aortic Valve Stenosis | Aortic Calcification Valve

Mexico
Edwards Lifesciences
Rundo International Pharmaceutical Research & Development Co.,Ltd.; Edwards... and other collaborators

Active, not recruiting

INSPIRIS China PMCF Study (INSPIRIS China)

Aortic Valve Replacement

China
Edwards Lifesciences

Suspended

INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance Study (INVIVITY)

Aortic Valve Replacement

United States
University Medical Centre Ljubljana

Not yet recruiting

Conventional Versus Left Bundle Branch Pacing in TAVI

Heart Failure | Aortic Valve Stenosis | Pacemaker-Induced Cardiomyopathy | Transcatheter Aortic Valve Implantation

Slovenia
Edwards Lifesciences

Completed

Surgical Treatment of Aortic Stenosis With a Next Generation Surgical Aortic Valve (TRITON)

Aortic Valve Stenosis | Aortic Valve Stenosis With Insufficiency

Austria, Germany
Jian'an Wang,MD,PhD

Not yet recruiting

Sizing-sTrategy of Bicuspid AoRtic Valve Stenosis With Transcatheter Self-expandable Valve (START)

Aortic Valve Stenosis

China
University of Göttingen

Recruiting

Exercise CMR in (p)LF-LG AS

Aortic Stenosis, Severe

Germany
Romanian Society of Cardiology

Recruiting

Romanian National Registry of Outcomes After Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis - RO-TAVI (RO-TAVI)

Aortic Valve Stenosis | Aortic Stenosis Symptomatic

Romania
Medtronic Cardiovascular

Active, not recruiting

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI). (SURTAVI)

Severe Aortic Stenosis

United States, Netherlands, Canada, Spain, Denmark, United Kingdom, Switzerland, Germany, Sweden
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2011-03) (2011-03)

Aortic Stenosis Symptomatic

Germany, Brazil
Medtronic Cardiovascular

Completed

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

Severe Aortic Stenosis

United States
Abbott Medical Devices

Completed

First in Human Experience of the St. Jude Medical TAVI Valve and Delivery System (SJM TAVI FIH)

Symptomatic Aortic Stenosis

United Kingdom
Abbott Medical Devices

Completed

Portico TAVI Implant With Transfemoral Delivery System

Symptomatic Aortic Stenosis

United Kingdom, Germany, Netherlands, Denmark, Australia
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis:CE-approval Cohort

Symptomatic Aortic Stenosis

Germany, Japan, Brazil
Symetis SA

Completed

Feasibility Trial on ACURATE™ Transapical Implantation in Patients With Severe Symptomatic Aortic Stenosis (2009-01) (TA-FIM)

Aortic Stenosis Symptomatic

Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...
Edwards Lifesciences

Unknown

Feasibility of Continuous Noninvasive Finger Arterial Blood Pressure Measurement for Detection and Staging of Aortic Stenosis (COaRt)

Aortic Stenosis, Calcific

Netherlands
HLT Inc.

Withdrawn

HLT transfemOral Replacement of aortIc Valve Via transcatherteriZatiON CANADA (HORIZON CANADA)

Severe Aortic Stenosis

Canada
St. Antonius Hospital

Completed

Patient Reported Health-Related Quality of Life After Limited Access and Conventional Aortic Valve Replacement (LIAR)

Quality of Life | Aortic Valve Stenosis | Limited Access Aortic Valve Replacement

Netherlands
Assistance Publique Hopitaux De Marseille

Completed

Five-year Outcomes of Rapid-deployment Aortic Valve Replacement With the Edwards Intuity TM Valve

Severe Aortic Valve Disease

France
Matteo Montorfano

Recruiting

Microvascular Function in Patients Undergoing Transcatheter Aortic Valve Implant (TAVI) for Severe Symptomatic Aortic Stenosis: Association With Myocardial Fibrosis

Severe Symptomatic Aortic Stenosis

Italy

Clinical Trials on Aortic Valve Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Armenia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations