Clinical Trials on Aortic Insufficiency in Hungary

Total 161 results

Semmelweis University Heart and Vascular Center

Completed

Saline Flush to Reduce the Amount of Residual Air Inside a Stentgraft Delivery System (SAFRANE)

Stroke | Aortic Aneurysm | Aortic Diseases | Aortic Aneurysm, Thoracic | Aortic Arch Aneurysm

Hungary
Pi-cardia

Active, not recruiting

The Leaflex™ Standalone Study Protocol

Aortic Valve Stenosis

Hungary
Michele De Bonis

Completed

Aortic Cross-clamp and Opening After Transcatheter Aortic Valve Implantation: a Real Issue?

Aortic Stenosis

Denmark, Hungary, Italy
Vascutek Ltd.

Recruiting

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches (PANTHER)

Aneurysm | Aortic Diseases | Carotid Artery Injuries | Aortic Arch | Dissection | Aortic Root Aneurysm | Aortic Root Dissection | Bypass Extremity Graft | Occlusive Vascular Disease

United States, Belgium, France, Hungary, Germany, Netherlands, Canada
Hungarian Institute of Cardiology
Semmelweis University

Unknown

Frailty and Cognitive Function Assessment of TAVI Patients

Quality of Life | Aortic Valve Stenosis | Heart Valve Disease

Hungary
Fresenius Kabi

Completed

Observational Study on Chronic Kidney Disease Treatment With a Ketosteril Supplemented Protein-restricted Diet

Chronic Kidney Disease

Hungary
BioVersys AG
CRU Hungary Kft; CRU Hungary Early Phase Unit

Completed

Pharmacokinetics and Safety of BV100 Administered as Single Intravenous Infusion to Subjects With Renal Impairment

Renal Impairment

Hungary
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Hepatically-Impaired Participants

Hepatic Insufficiency

Germany, Hungary
Chiesi Hungary Ltd.
Chiesi Slovenija, d.o.o.

Recruiting

Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant Patients (LTA)

Liver Failure

Hungary, Slovenia
Bolton Medical

Completed

Global Post-market Registry for the Treovance Stent-graft. (RATIONALE)

Abdominal Aortic Aneurysm

Spain, Greece, Norway, Germany, Ireland, Sweden, Italy, Hong Kong, Thailand, Netherlands, Vietnam, Chile, United Kingdom, Denmark, Hungary, Poland, Venezuela
Zealand Pharma

Completed

Pharmacokinetic Profile of Glepaglutide After a Single Injection in Subjects With Varying Degrees of Renal Function

Renal Impairment

Hungary, Poland
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function

Hepatic Insufficiency

Hungary, Czechia, Slovakia
University of Pecs
Fresenius Medical Care North America; Teaching Hospital Markusovszky, Szombathely

Unknown

Genetical Background of Non-alcoholic Fatty Liver Disease (NAFLD) in Diabetes Mellitus and in Chronic Kidney Disease (NAFLDDMCKD)

Diabetes Mellitus | Non-alcoholic Fatty Liver Disease | Chronic Kidney Disease

Hungary
Bristol-Myers Squibb

Completed

An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function

Congestive Heart Failure | Liver Dysfunction | Heart Decompensation | Cardiac Failure | Liver Insufficiency | Myocardial Failure | Hepatic Failure

Hungary, Poland
Novo Nordisk A/S

Completed

A Trial Investigating the NN1250 Concentration-time Curve in Subjects With Various Degrees of Renal Impairment and in Subjects With Normal Renal Function

Healthy | Diabetes

Hungary
Semmelweis University

Completed

Safety of Remdesivir Treatment in COVID-19 Patients Requiring Hemodialysis (REM-HD)

Covid19 | End Stage Renal Failure on Dialysis

Hungary
Daiichi Sankyo, Inc.
PRA Health Sciences

Completed

Pilot PK/PD Study of DS-1093a in Patients With Chronic Kidney Disease

Chronic Renal Disease | Renal Anemia

Czechia, Hungary
TME Pharma AG

Completed

A Phase I Clinical Trial to Evaluate the Effect of Renal Impairment on Pharmacokinetics of NOX-E36

Renal Impairment

Hungary, Moldova, Republic of
Novartis Pharmaceuticals

Completed

Pharmacokinetics of Certoparin in Subjects With Renal Insufficiency and Healthy Subjects

Renal Insufficiency

Hungary
Abbott

Completed

A Double-blind, Randomized, Multicenter, Cross-over Study to Compare the Effect of Creon N and Creon® on Fat Digestion in Subjects ≥ 12 Years of Age With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Hungary, Spain
Abbott Products
Quintiles, Inc.; Data Map GmbH

Completed

Creon After Pancreatic Surgery

Pancreatic Insufficiency

Bulgaria, Germany, Hungary, Italy
MedDay Pharmaceuticals SA
Eurofins Optimed

Terminated

RI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Renal Impaired Patients and Healthy Subjects

Healthy Volunteers | Impaired Renal Function

France, Hungary
Takeda

Completed

A Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics (PK) of a Single Intravenous (IV) TAK-954

Renal Impairment | Healthy Volunteers

Czechia, Hungary
Semmelweis University

Recruiting

The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate (NEOKOFF22)

Premature Birth | Respiratory Failure | Apnea of Prematurity

Hungary
AbbVie (prior sponsor, Abbott)
Planimeter Ltd

Completed

Observational Study to Evaluate the Time to Achieving the Maintenance Dose of Zemplar® (Paricalcitol Injection) in the Treatment of Patients Suffering From End-stage Renal Disease and Severe Over-reactivity of the Parathyroid Glands

Kidney Failure, Chronic

Hungary
Eli Lilly and Company

Completed

A Single Dose Study of LY2605541 in Participants With Liver Impairment

Hepatic Insufficiency | Diabetes Mellitus, Type 2 | Healthy Volunteers

Germany, Hungary
University of Pecs

Completed

Urinary Actin, as a Potential Marker of Sepsis-related Acute Kidney Injury

Sepsis | Acute Kidney Injury Due to Sepsis

Hungary
InnovHeart

Active, not recruiting

SATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation

Heart Valve Diseases | Mitral Regurgitation | Valve Heart Disease | Mitral Valve Disease | Mitral Disease

Lithuania, Denmark, Hungary
University of Debrecen

Completed

Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain

Pain | Inadequate or Impaired Respiratory Function

Hungary
Micro Interventional Devices

Recruiting

Study of Transcatheter Tricuspid Annular Repair (STTAR)

Tricuspid Regurgitation

Denmark, Poland, Hungary, Latvia, Lithuania
GlaxoSmithKline

Completed

Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment

Pulmonary Disease, Chronic Obstructive

Czechia, Hungary
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
University of Pecs

Not yet recruiting

Early Haemadsorption in Major Burns

Burns | Shock | Multiple Organ Failure | Cytokine Storm | Renal Dysfunction | Organ Dysfunction Syndrome, Multiple

Hungary
Fresenius Medical Care Deutschland GmbH
Institut Dr. Schauerte GmbH (IDS)

Completed

Comparison of Clinical Performance and Hemocompatibility of Dialyzers Applied During Post-dilution Online Hemodiafiltration (eMPORAIII)

Renal Failure | End Stage Renal Disease

Germany, Czechia, Hungary
Semmelweis University

Recruiting

Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort (POMODORI)

Obesity | Polycystic Ovary Syndrome | Insulin Resistance | Primary Ovarian Insufficiency | Infertility, Female | Mitochondrial Alteration

Hungary
FORUM Pharmaceuticals Inc
PRA Health Sciences

Completed

EVP-6124 Renal Impairment Study

Renal Impairment

Czech Republic, Hungary
Bristol-Myers Squibb

Completed

A Study to Assess the Safety of Experimental Medication BMS986165 in Participants With Normal Kidney Function and Participants With Mild to End-Stage Kidney Disease.

Renal Impairment | Healthy Volunteer

United States, Czechia, Hungary, Poland
Cytokinetics

Recruiting

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM (MAPLE-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, Denmark, Spain, Netherlands, United Kingdom, France, China, Israel, Germany, Italy, Hungary, Canada
Medtronic Cardiovascular

Completed

CoreValve™ Evolut R™ FORWARD Study (FORWARD)

Aortic Valve Stenosis

Netherlands, Saudi Arabia, Italy, Germany, Sweden, Spain, Australia, France, United Kingdom, Belgium, Greece, Hungary, Israel, Canada, Colombia, South Africa, Czechia, Norway, Panama, Poland, Portugal
Cytokinetics

Enrolling by invitation

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM (FOREST-HCM)

Symptomatic Hypertrophic Cardiomyopathy (HCM)

United States, France, Israel, Spain, United Kingdom, Italy, Portugal, Poland, Hungary, Denmark, Netherlands, Germany, Czechia
Novo Nordisk A/S

Completed

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Various Degrees of Impaired Renal Function

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Hungary, Czechia
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy (MEMENTO)

Cardiomyopathy, Hypertrophic

United States, Argentina, Australia, Belgium, Canada, Czechia, Hungary, Poland, Switzerland, France, Austria, Finland, Germany, Greece, Italy, Spain, United Kingdom
University of Pecs

Completed

Presepsin:Gelsolin Ratio in Sepsis-related Organ Dysfunction

Sepsis | Septic Shock | Acute Respiratory Distress Syndrome | Acute Kidney Injury Due to Sepsis

Hungary
Cytokinetics
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Completed

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM (SEQUOIA-HCM) (SEQUOIA-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, France, Spain, Portugal, Germany, China, United Kingdom, Israel, Netherlands, Denmark, Czechia, Hungary, Italy, Poland
Astellas Pharma Inc

Completed

Renal Impairment Study With ASP1941

Type 2 Diabetes Mellitus

Hungary, Poland, Czechia, Slovakia
Solvay Pharmaceuticals

Terminated

Dose-ranging Study to Evaluate Efficacy of SLV339 in Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis

Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis

Czech Republic, Denmark, Hungary, Latvia, Poland, Russian Federation, Sweden
Meril Life Sciences Pvt. Ltd.

Recruiting

LANDMARK Trial: a Randomised Controlled Trial of Myval THV (LANDMARK)

Aortic Valve Stenosis

Sweden, Hungary, France, Belarus, Croatia, Germany, Netherlands, New Zealand, Poland, Portugal, Slovakia, Slovenia, Spain, Italy, Brazil, Estonia, Greece
Bristol-Myers Squibb

Active, not recruiting

A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy (ODYSSEY-HCM)

Cardiomyopathy, Hypertrophic

Spain, Austria, Belgium, Brazil, Canada, Denmark, France, Germany, Hungary, Israel, Japan, Netherlands, Norway, Poland, Portugal, United Kingdom, United States, Australia, China, Czechia, India, Italy, Korea, Republic of
Abbott
AbbVie; Parexel; Datamap; LKF Laboratorium für Klinische Forschung GmbH; Analytical... and other collaborators

Completed

Efficacy and Safety Study of Creon IR in Subjects With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Exocrine Pancreatic Insufficiency in Subjects With Cystic Fibrosis

Spain, Czech Republic, Hungary, Poland
AzurRx SAS

Completed

Phase 2 Combination Study With Escalating Doses of MS1819-SD on Top of a Stable Dose of PPEs

Cystic Fibrosis | Cystic Fibrosis Gastrointestinal Disease | Cystic Fibrosis of Pancreas

Turkey, Hungary

Clinical Trials on Aortic Insufficiency in Hungary

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Lebanon

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Rare Diseases

Drug Interventions

Dietary Supplements

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