Clinical Trials on Asthma; Allergic Rhinitis in Canada

Total 613 results

The Hospital for Sick Children

Completed

Dynamic Contrast Enhanced Magnetic Resonance Perfusion Imaging in Congenital Heart Disease and Lung Disease

Asthma | Cystic Fibrosis | Heart Disease

Canada
DBV Technologies

Recruiting

Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Children 4-7 Years of Age (VITESSE)

Allergy, Peanut

United States, Canada, France, Germany, Ireland, Netherlands, Spain, United Kingdom, Australia
University of Alberta
Women and Children's Health Research Institute, Canada; Pediatric Parent Advisory...

Active, not recruiting

Supporting Parents to Choose Wisely

Parents | Pediatric ALL | Bronchiolitis | Common Cold | Pharyngitis | Acute Otitis Media | Acute Asthma

Canada
MedImmune LLC

Completed

A Study to Evaluate the Safety and Tolerability of the Administration of MEDI-528 When Administered in Multiple Doses to Adults With Mild Persistent Asthma

Asthma

United States, Canada
Roche Global Development

Completed

A Study of Two Forms of Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Teva Branded Pharmaceutical Products R&D, Inc.

Terminated

A Study of Reslizumab in Patients 12 Years of Age and Older With Severe Eosinophilic Asthma

Eosinophils, Asthma

United States, Belgium, Canada, Czechia, France, Germany, Hungary, Israel, Poland, Romania, Russian Federation, Spain, Ukraine
Unity Health Toronto
University of Toronto; Glycemic Index Laboratories, Inc; Iowa State University; Ingredion Incorporated

Completed

Digestibility of Selected Resistant Starches in Humans

Ileostomy - Stoma | Malabsorption; Carbohydrate

Canada
Genentech, Inc.

Completed

A Study of MEMP1972A in the Prevention of Allergen-Induced Airway Obstruction in Patients With Mild Asthma (SOLARIO)

Asthma

Canada, Sweden
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma

Moderate to Severe Asthma

Korea, Republic of, United States, Spain, Poland, Japan, Canada, Germany, Belgium, Argentina
Aimmune Therapeutics, Inc.

Completed

Longer-term Study of AR101 in Subjects Who Participated in a Prior AR101 Study (ARC008)

Peanut Allergy

United States, Canada, Spain, Netherlands, Germany, United Kingdom, Ireland, Sweden, France, Italy
ProQR Therapeutics

Terminated

An Open-Label Extension Study to Evaluate Safety & Tolerability of QR-421a in Subjects With Retinitis Pigmentosa (HELIA)

Retinitis Pigmentosa | Usher Syndrome Type 2

United States, Canada, France
Humanigen, Inc.

Completed

Effect of KB003 in Subjects With Asthma Inadequately Controlled by Corticosteroids (KB003-04)

Moderate-to-Severe Asthma

France, United Kingdom, United States, Australia, Poland, Ukraine
Jaeb Center for Health Research
Foundation Fighting Blindness

Active, not recruiting

Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A)

Usher Syndrome, Type 2A | Retinitis Pigmentosa 39

United States, Canada, France, Germany, Netherlands, United Kingdom
McMaster University
Novartis

Completed

Study of the Steroid Sparing Effect of Xolair (Omalizumab) in Patients With Persistent Eosinophilic Bronchitis

Eosinophilic Bronchitis | Steroid and/or Prednisone Dependent Asthma

Canada
AstraZeneca

Completed

Study to Evaluate Efficacy & Safety of Tralokinumab in Subjects With Asthma Inadequately Controlled on Corticosteroids (MESOS)

Asthma

Canada, Denmark, United Kingdom
The Hospital for Sick Children

Recruiting

Measures of Respiratory Health (MRH) (MRH)

Asthma | Cystic Fibrosis | Sickle Cell Anemia | Bronchiolitis Obliterans

Canada
Ottawa Hospital Research Institute

Completed

Undiagnosed COPD and Asthma Population Study (UCAP)

Asthma | COPD

Canada
MedImmune LLC

Terminated

A Phase 2A Study to Evaluate the Safety and Effect on Exercise Challenge Testing of MEDI-528 in Adults With Asthma

Asthma

United States, Canada
Nutricia Research

Completed

A Clinical Study to Investigate the Effect of a Partially Hydrolysed Infant Formula With Added Synbiotics on Gut Microbiota Composition and Clinical Effectiveness in Infants at High Risk of Developing Allergy (TEMPO)

Immunity

Hong Kong, Taiwan, Singapore, Netherlands, Israel, Spain, United Kingdom, Slovakia, Belgium, Germany, Czechia, Hungary, Italy
ProQR Therapeutics

Completed

Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Stellar)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Canada, France
Johns Hopkins University
Mayo Clinic; Medical University of Graz; Radboud University Medical Center; University... and other collaborators

Recruiting

Oral N-acetylcysteine for Retinitis Pigmentosa (NAC Attack)

Retinitis Pigmentosa

United States, Austria, Mexico, Netherlands, United Kingdom, Germany, Canada, Switzerland
Jaeb Center for Health Research
Foundation Fighting Blindness

Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants (Uni-Rare)

Retinitis Pigmentosa | Inherited Retinal Degeneration

United States, United Kingdom, France, Brazil, Finland, Israel, Netherlands, Switzerland, Australia, Canada, Mexico
Novartis
Genentech, Inc.; Tanox

Completed

Omalizumab in Adult and Adolescent Patients With Severe Persistent Allergic Asthma

Asthma

Canada, Germany, Spain, Belgium, Switzerland, Israel, Portugal, Greece, Hungary, Poland, Ireland, Norway, Denmark, Sweden, Italy, United Kingdom, Turkey
Sanofi
Regeneron Pharmaceuticals

Recruiting

Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)

Asthma | Wheezing

Canada, United States, Argentina, Brazil
MedImmune LLC

Completed

A Phase 2 Study to Evaluate the Safety and Efficacy of Intravenously Administered Benralizumab (MEDI-563).

Asthma

United States, Canada
AstraZeneca

Completed

A Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents With Uncontrolled Asthma (STRATOS2)

Uncontrolled Asthma

United States, Canada, Italy, United Kingdom, Philippines, Japan, Russian Federation, South Africa, Taiwan, Czechia, Mexico, Ukraine, Chile
DBV Technologies

Completed

Follow-up of the VIPES Study to Evaluate Efficacy and Safety of Viaskin Peanut in Adults and Children (OLFUS-VIPES)

Peanut Allergy

United States, Netherlands, France, Canada
GlaxoSmithKline

Completed

Crossover Study Comparing Fluticasone Furoate (FF)/Vilanterol (VI) Once Daily Versus Fluticasone Propionate (FP) Twice Daily in Subjects With Asthma and Exercise-Induced Bronchoconstriction (EIB)

Asthma

United States, Canada
Genentech, Inc.

Recruiting

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough

Chronic Refractory Cough (CRC) With Non-atopic Asthma | CRC With Atopic Asthma | Unexplained Chronic Cough | CRC With Chronic Obstructive Pulmonary Disease | CRC With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis

United States, Australia, United Kingdom, Canada
Hoffmann-La Roche

Completed

Evaluation of Various Doses of Ro 27-2771 (Test Drug) in Asthmatic Patients Not Treated With Inhaled Corticosteroids

Asthma

Australia, United States, Canada, Mexico, Puerto Rico
Boehringer Ingelheim

Completed

Efficacy and Safety of 4 Weeks Treatment With Inhaled BI 1744 CL in Patients With COPD.

Pulmonary Disease, Chronic Obstructive | Asthma

United States, Canada, Germany, Netherlands
GlaxoSmithKline

Completed

Study of Mepolizumab Safety Syringe in Asthmatics

Asthma

Canada, Netherlands, United States, Sweden, Russian Federation
GlaxoSmithKline

Completed

An Open-label Study to Evaluate Correct Use and Ease of Use of the ELLIPTA DPI in Pediatric Subjects With Asthma

Asthma

Canada, United States
Chiesi Farmaceutici S.p.A.

Completed

AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS) (ATLANTIS)

Asthma

United States, Brazil, Canada, China, Germany, Italy, Netherlands, Spain
McMaster University
St. Joseph's Healthcare Hamilton

Recruiting

Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease

Bronchiectasis | Chronic Obstructive Pulmonary Disease | Asthma | Emphysema | Pulmonary Fibrosis | Alpha 1-Antitrypsin Deficiency | Bronchopulmonary Dysplasia | Sarcoidosis, Pulmonary

Canada
University of Calgary

Active, not recruiting

ENCOMPASS: Expansion Study B, RCT (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
AstraZeneca

Completed

Study to Assess Functionality, Reliability, and Performance of a Pre-filled Syringe With Benralizumab Administered at Home

Asthma

United States, Canada
GlaxoSmithKline

Completed

Omalizumab to Mepolizumab Switch Study in Severe Eosinophilic Asthma Patients

Asthma

United States, Argentina, France, Germany, Spain, Canada, Sweden, Netherlands, Belgium
MedImmune LLC

Completed

A Study to Assess Selected Biomarkers in Subjects Requiring Daily Inhaled Corticosteroids for Persistent Asthma

Asthma

United States, Canada
AstraZeneca
Parexel

Recruiting

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA) (DOMINICA)

Asthma

Korea, Republic of, Spain, United States, Argentina, France, Italy, Taiwan, Germany, United Kingdom, Poland, Canada
AstraZeneca
Amgen

Completed

Tezepelumab Home Use Study (PATH-HOME)

Asthma

United States, Canada, Poland, Japan
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Safety and Effectiveness of JNJ-39758979 in the Treatment of Adults With Persistent Asthma

Asthma

United States, India, Canada, Romania
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Reslizumab in Patients With Eosinophilic Asthma

Eosinophilic Asthma

United States, Argentina, Brazil, Canada, France, Mexico, Germany, Greece, Korea, Republic of, Peru, Romania, Russian Federation, Slovakia, Taiwan, Ukraine
GlaxoSmithKline

Completed

Cessation Versus Continuation of Long-term Mepolizumab in Severe Eosinophilic Asthma Patients

Asthma

United States, Argentina, Australia, Canada, France, Germany, Japan, Korea, Republic of, Netherlands, Poland, Romania, Russian Federation, Spain, Ukraine
GlaxoSmithKline

Not yet recruiting

A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants 12 Years of Age and Older With Asthma

Asthma

Argentina, United States, Canada, Panama, Greece, France, Poland, Italy, United Kingdom
MedImmune LLC

Completed

A Study to Evaluate the Effectiveness and Safety of MEDI-528 in Adults

Asthma

United States, Canada, Peru, Taiwan, Colombia, Brazil, Panama, Philippines, Argentina, Costa Rica
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Reslizumab (0.3 or 3.0 mg/kg) as Treatment for Patients (12-75 Years of Age) With Eosinophilic Asthma

Eosinophilic Asthma

United States, Belgium, Colombia, Hungary, Israel, Poland, Sweden, Argentina, Brazil, Canada, France, Mexico, Netherlands
GlaxoSmithKline

Completed

A Clinical Study to Evaluate the Effect of the Connected Inhaler System (CIS) on Adherence to Maintenance Therapy in Poorly Controlled Asthmatic Subjects

Asthma

United States, Canada, Germany, Spain, Netherlands, Italy, United Kingdom
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Dupilumab's Effects on Airway Inflammation in Patients With Asthma (EXPEDITION)

Asthma

Denmark, United States, Canada, Germany, Sweden, United Kingdom
Sanofi

Recruiting

Long-term Safety and Efficacy Evaluation of Subcutaneous Amlitelimab in Adult Participants With Moderate-to-severe Asthma Who Completed Treatment Period of Previous Amlitelimab Asthma Clinical Study (RIVER-ASTHMA)

Asthma

Korea, Republic of, Argentina, Chile, South Africa, United States, Hungary, Poland, Turkey, United Kingdom, Canada, Japan

Clinical Trials on Asthma; Allergic Rhinitis in Canada

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