Clinical Trials on Atrial Myxoma, Familial

Total 18908 results

Aegerion Pharmaceuticals, Inc.

Withdrawn

Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering Therapy

Homozygous Familial Hypercholesterolemia
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)

Heterozygous Familial Hypercholesterolemia (HeFH)
Cerenis Therapeutics, SA

Completed

Exploratory Study of Plaque Regression (EXPRESS)

Heterozygous Familial Hypercholesterolemia

Canada
Instituto Nacional de Ciencias Medicas y Nutricion...

Recruiting

REgistry of Pulmonary Arterial Hypertension Associated With CONNECTIVE Tissue Diseases (RECONNECTIVE) (RECONNECTIVE)

Connective Tissue Diseases | Pulmonary Arterial Hypertension

Mexico
University Hospital Inselspital, Berne

Recruiting

MRI-markers to Monitor Small Vessel Disease Dynamics in the Prognosis of Small Vessel Disease-associated, Cerebrovascular Events (MRI-PRO-SVD)

Cerebral Small Vessel Diseases | Intracerebral Hemorrhage | CAA - Cerebral Amyloid Angiopathy

Switzerland
University of Pennsylvania

Completed

Is Family Screening Improved by Genetic Testing of Familial Hypercholesterolemia (IFIGhTFH)

Hypercholesterolemia, Familial
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
AstraZeneca

Completed

An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia

Familial Hypercholesterolaemia

United States, Netherlands, Norway, Canada, Belgium
Cardiovascular Innovation and Research Institute
Valley View Hospital

Recruiting

Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.

Coronary Artery Disease | Atrial Fibrillation (AF)

United States
Meshalkin Research Institute of Pathology of Circulation

Unknown

Surgical Ablation of Long-standing Persistent AF During CABG (LABARFA)

Coronary Artery Disease

Russian Federation
Federal Research and Clinical Center of Physical-Chemical...
Endocrinology Research Centre, Moscow

Completed

Assessment of the Health Improvement of Obese Patients After Fecal Microbiota Transplantation (FMT)

Obesity; Familial

Russian Federation
Centre Hospitalier Universitaire Dijon

Completed

Sagittal Imbalance and Lumbar Stenosis Surgery: Decompression Without Implant (CLE/EOS)

Lumbar Stenosis, Familial

France
University of Pennsylvania
University of Amsterdam; University of Cape Town; University of Witwatersrand...

Recruiting

HoFH, the International Clinical Collaborators Registry (HICC)

Homozygous Familial Hypercholesterolemia

United States, Netherlands, South Africa
LIB Therapeutics LLC

Completed

Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in HoFH

Homozygous Familial Hypercholesterolemia

United States, Israel, Norway, South Africa, Turkey, India
AstraZeneca

Completed

A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia (HYDRA)

Homozygous Familial Hypercholesterolemia (HoFH)

Malaysia, Canada, Israel, Netherlands, Taiwan, Belgium, Denmark
Novartis

Completed

Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia

Mixed Dyslipidemia | Heterozygous Familial Hypercholesterolemia

Switzerland
Actelion

Completed

Trial of Iloprost Inhaled Solution as Add-On Therapy With Bosentan in Subjects With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension | Pulmonary Hypertension | Ayerza Syndrome

United States
Amryt Pharma

Recruiting

LOWER: Lomitapide Observational Worldwide Evaluation Registry (LOWER)

Homozygous Familial Hypercholesterolemia

Italy, United States, Argentina, Canada, France, Greece, Netherlands, United Kingdom
Amgen

Completed

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders (TAUSSIG)

Severe Familial Hypercholesterolemia

Italy, Czechia, United States, Israel, New Zealand, South Africa, France, Spain, Australia, Belgium, Canada, Netherlands, Hong Kong, Brazil, United Kingdom, Greece, Japan, Lebanon
Bristol-Myers Squibb

Terminated

Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other Causalities

Primary Familial Dilated Cardiomyopathy

United States, Germany, Spain, United Kingdom
LIB Therapeutics LLC
Medpace, Inc.

Completed

Study to Assess the Efficacy and Safety of LIB003 in HeFH Patients on Oral Lipid Therapy Needing Further LDL-C Reduction (LIBerate-FH)

Heterozygous Familial Hypercholesterolemia

United States, Israel, Norway, South Africa, Turkey
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study to Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia

Homozygous Familial Hypercholesterolemia

China
Regeneron Pharmaceuticals

Completed

Evaluate the Efficacy and Safety of Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia

Homozygous Familial Hypercholesterolemia

United States, Australia, Austria, Netherlands, Taiwan, Ukraine
Novartis Pharmaceuticals

Completed

A Study of Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (ORION-5)

Homozygous Familial Hypercholesterolemia

Hong Kong, Israel, Russian Federation, Serbia, South Africa, Taiwan, Turkey, Ukraine
Regeneron Pharmaceuticals
Sanofi

Completed

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Hypercholesterolemia | Heterozygous Familial Hypercholesterolemia

United States, Canada
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy (ODYSSEY ESCAPE)

Heterozygous Familial Hypercholesterolemia

United States, Germany
Laval University
Amgen

Completed

Lp(a) and Aortic Valve Calcification (FHLPA)

Heterozygous Familial Hypercholesterolemia

Canada
Akcea Therapeutics
Ionis Pharmaceuticals, Inc.

Withdrawn

Study of AKCEA-ANGPTL3-LRX (ISIS 703802) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Homozygous Familial Hypercholesterolemia

Canada
Amgen

Completed

Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities (TESLA)

Homozygous Familial Hypercholesterolemia

New Zealand, South Africa, France, United States, Spain, Belgium, Czechia, Italy, Netherlands, Hong Kong, Canada, Lebanon
Aegerion Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy

Familial Hypercholesterolemia - Homozygous

Japan
Aegerion Pharmaceuticals, Inc.
FDA Office of Orphan Products Development

Completed

A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)

Homozygous Familial Hypercholesterolemia

United States, Canada, Italy, South Africa
National Eye Institute (NEI)

Completed

Clinical and Genetic Studies of Familial Exudative Vitreoretinopathy

Eye Diseases | Exudatiaon | Avascular Retina | Retina Fold | Familial Exudative Vitreoretinopathy | FEVR

Canada, United Kingdom
Pfizer

Completed

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia (SPIRE-FH)

Heterozygous Familial Hypercholesterolemia

Canada, Netherlands, United Kingdom, United States, Spain, Poland, Finland, Norway, South Africa, Italy, Bulgaria
Laval University

Completed

Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial Hypercholesterolemia (APHERESE)

Homozygous Familial Hypercholesterolemia

Canada
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy) (ODYSSEY FH II)

Heterozygous Familial Hypercholesterolemia

United Kingdom, Netherlands, Czech Republic, Norway
Cerenis Therapeutics, SA

Completed

Effect of CER-001 on Plaque Volume in Homozygous Familial Hypercholesterolemia (HoFH) Subjects (MODE)

Homozygous Familial Hypercholesterolemia

United States, Canada, Italy, Netherlands, United Kingdom
Aegerion Pharmaceuticals, Inc.
University of Pennsylvania; Doris Duke Charitable Foundation

Completed

Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor

Homozygous Familial Hypercholesterolemia

United States
The University of Western Australia
National Health and Medical Research Council, Australia

Unknown

Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils (FIFH)

Familial Hypercholesterolaemia | Hypertriglyceridaemia

Australia
Umeå University

Completed

The Effect of Diflunisal on Familial Transthyretin Amyloidosis (DFNS01)

Amyloidosis

Sweden
VIVE - The Danish Center for Social Science Research
KFUMs Sociale Arbejde; FDF; KFUM spejderne

Completed

The Effectivenes of Family Club Denmark #Strongertogether (FCD)

Vulnerable Families

Denmark
GCS IHFB Cognacq-Jay
Fondation de France

Completed

Incidence and Risk Factors of Prolonged Grief in Palliative Care Units (FAMI-LIFE)

Bereaved Families

France
Kun Hua

Active, not recruiting

Predictors of Postoperative Atrial Fibrillation After CABG (CODA-AF)

Coronary Artery Disease | Atrial Fibrillation New Onset

China
Icahn School of Medicine at Mount Sinai
Bristol-Myers Squibb

Completed

Antithrombotic Strategy Variability In ATrial Fibrillation and Obstructive Coronary Disease Revascularized With PCI - The AVIATOR 2 Registry

Non-valvular Atrial Fibrillation

United States
Organon and Co

Completed

Evaluation of the Safety, Tolerability and Efficacy of Ezetimibe on a Select Population of Filipinos With Hypercholesterolemia (Study P04748)(COMPLETED)

Primary Hypercholesterolemia | Homozygous Familial Hypercholesterolemia
HDL Therapeutics
MedStar Heart and Vascular Institute

Unknown

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Homozygous Familial Hypercholesterolemia | HoFH

United States
Chinese SLE Treatment And Research Group

Recruiting

Anti-CD20 Antibodies for Treatment of SLE-PAH

Systemic Lupus Erythematosus | Pulmonary Arterial Hypertension

China
Mallinckrodt

Completed

Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing

Idiopathic Pulmonary Arterial Hypertension | Cardiomyopathy

United Kingdom, United States, France, Spain, Netherlands
United Therapeutics
Lung Biotechnology PBC

Recruiting

A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension (ARTISAN)

Pulmonary Arterial Hypertension

United States
Liquidia Technologies, Inc.
FGK Clinical Research GmbH

Terminated

Hemodynamic Evaluation of Dose-response and Safety of Dry Powder Inhalation of Treprostinil

Pulmonary Arterial Hypertension

France, Germany
Actelion

Completed

REPAIR: Right vEntricular Remodeling in Pulmonary ArterIal hypeRtension (REPAIR)

Pulmonary Arterial Hypertension

United States, Israel, France, Netherlands, Malaysia, Germany, Australia, United Kingdom, Hong Kong, Italy, Russian Federation, Singapore

Clinical Trials on Atrial Myxoma, Familial

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