Clinical Trials on Augmented Renal Clearance

Total 9703 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Cyclophosphamide in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Fanconi's Anemia

Fanconi Anemia

United States, Brazil
Children's Hospital Medical Center, Cincinnati
FDA Office of Orphan Products Development

Completed

Oxandrolone for the Treatment of Bone Marrow Aplasia in Fanconi Anemia

Fanconi Anemia

United States
University of Minnesota

Unknown

Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia
Xencor, Inc.

Recruiting

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

Colorectal Cancer | Castration-resistant Prostate Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Ovarian Cancer, Epithelial | TNBC - Triple-Negative Breast Cancer | Renal Cell Carcinoma, Clear Cell | Melanoma Excluding Uveal Melanoma | Non-small Cell Lung Cancer, Squamous or...

United States
Advice Pharma Group srl

Recruiting

KidneYou - Innovative Digital Therapy

Diabetes | Chronic Kidney Diseases | Tuberous Sclerosis | Albuminuria | Treatment Adherence | Arterial Hypertension | Treatment Adherence and Compliance | Nephronophthisis | Polycystic Kidney | Chronic Glomerulonephritis | Cystic Kidney Diseases | Cortical Cystic Disease | Cystic Diseases

Italy
OncoC4, Inc.
National Cancer Institute (NCI)

Recruiting

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC (PRESERVE-001)

Cervical Cancer | Small Cell Lung Cancer | Adenoid Cystic Carcinoma | Metastatic Renal Cell Carcinoma | Metastatic Colorectal Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Breast Cancer | Advanced Solid Tumor | Metastatic Melanoma | Pancreas Cancer | Metastatic... and other conditions

United States, Australia
Corvus Pharmaceuticals, Inc.

Completed

CPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced Cancers

Sarcoma | Cervical Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Bladder Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Renal Cell Cancer | Non-hodgkin Lymphoma | Metastatic Castration Resistant Prostate...

United States, Australia
Amgen

Completed

Assessment of Quality of Life in Patients With Symptomatic Chemotherapy-induced Anaemia

Cancer | Breast Cancer | Anemia | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Endometrial Cancer | Solid Tumors | Renal Cancer

France, Italy, Netherlands, Belgium, Romania, Poland, Austria, Greece, Germany
Dana-Farber Cancer Institute
National Cancer Institute (NCI); National Human Genome Research Institute (NHGRI)

Recruiting

Video Education With Result Dependent dIsclosure (VERDI)

Melanoma | Sarcoma | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Renal Cancer | Genetic Testing

United States
Complejo Hospitalario Universitario de Albacete
University of Warwick; University Hospitals Coventry and Warwickshire NHS Trust and other collaborators

Not yet recruiting

An Integrated Solution for Sustainable Care for Multimorbid Elderly Patients With Dementia (CAREPATH)

Behavioral Symptoms | Coronary Artery Disease | Heart Failure | Stroke | Hypertension | Diabetes | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Malnutrition | Asthma | Dementia | Alzheimer Disease | Frailty | Sarcopenia | Comorbidities and Coexisting Conditions

Spain
University of California, San Francisco
University of Colorado, Denver; The Methodist Hospital Research Institute

Terminated

Mild Hypothermia and Acute Kidney Injury in Liver Transplantation (MHALT)

End Stage Liver Disease | Chronic Kidney Diseases | Hepatitis B | Hepatocellular Carcinoma | Cirrhosis | Acute Kidney Injury | NASH - Nonalcoholic Steatohepatitis | Liver Transplant; Complications | Alcoholic Cirrhosis | Hepatitis c

United States
Eurasian Association of Therapists

Completed

Analysis of Health Status of Сomorbid Adult Patients With COVID-19 Hospitalised in Fourth Wave of SARS-CoV-2 Infection (ACTIV4)

Myocardial Infarction | Stroke | COVID-19 | Diabetes Mellitus | Chronic Kidney Diseases | Ischemic Stroke | Anemia | Atrial Fibrillation | Asthma | Myocarditis | Ischemic Heart Disease | Chronic Heart Failure | Copd | Overweight and Obesity | Pulmonary Embolism | Oncology | Arrythmia | DVT | Hypertensive Heart Disease

Russian Federation
Calithera Biosciences, Inc

Completed

Study of the Glutaminase Inhibitor CB-839 in Solid Tumors

Renal Cell Carcinoma | Non Small Cell Lung Cancer | Mesothelioma | Solid Tumors | Triple-Negative Breast Cancer | Fumarate Hydratase (FH)-Deficient Tumors | Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST) | Succinate Dehydrogenase (SDH)-Deficient Non-gastrointestinal... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

Bladder Carcinoma | Kidney Carcinoma | Prostate Carcinoma | Genitourinary System Neoplasm

United States
HiFiBiO Therapeutics

Active, not recruiting

A Study of HFB301001 in Adult Patients With Advanced Solid Tumors

Melanoma | Soft Tissue Sarcoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Uterine Carcinosarcoma | Head and Neck Squamous Cell Carcinoma

United States, Spain
Pharming Technologies B.V.

Terminated

Prevention of Acute Kidney Injury in Patients With NSTEMI (AKI)

Non-ST Elevation Myocardial Infarction (NSTEMI)

Switzerland
The University of Texas Health Science Center at...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection (NIRVANA)

Acute Kidney Injury | SARS-CoV-2 Infection

United States
Mirati Therapeutics Inc.

Terminated

A Phase 2 Study of Sitravatinib in Combination With PD-(L)1 Checkpoint Inhibitor Regimens in Patients With Advanced or Metastatic Urothelial Carcinoma

Urothelial Carcinoma Bladder | Urothelial Carcinoma | Urothelial Carcinoma Ureter | Urothelial Carcinoma of the Renal Pelvis and Ureter | Urothelial Carcinoma Urethra

United States
AvenCell Europe GmbH
GCP-Service International Ltd. & Co. KG

Terminated

Study With Bispecific Antibody Engaging T-cells, in Patients With Progressive Cancer Diseases With Positive PSCA Marker

Transitional Cell Carcinoma | Prostate Cancer | Non-small Cell Lung Cancer | Renal Cancer

Germany
Boston Children's Hospital

Completed

Pilot Study of Metformin for Patients With Fanconi Anemia

Fanconi Anemia

United States
Imperial College London
4D pharma plc

Active, not recruiting

MRx0518 in Patients With Solid Tumours Waiting Surgical Removal of the Tumour (MICROBIOME)

Melanoma | Breast Cancer | Head and Neck Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Renal Cancer | Urethral Cancer | Uterine Cancer

United Kingdom
Masonic Cancer Center, University of Minnesota

Completed

Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia

Fanconi Anemia

United States
Hospital Universitari Vall d'Hebron Research Institute
CIEMAT; CIBERER

Completed

Clinical Phase II Trial to Evaluate CD34+ Cells Mobilization and Collection in Patients With Fanconi Anemia for Subsequent Transduction With a Lentiviral Vector Carring FANCA Gene. FANCOSTEM-1

Fanconi Anemia

Spain
Mario Negri Institute for Pharmacological Research

Completed

Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency (ALADIN2)

Autosomal Dominant Polycystic Kidney Disease

Italy
National Heart, Lung, and Blood Institute (NHLBI)
Children's Hospital Medical Center, Cincinnati

Completed

Blood Cell Collection for Future Use in Individuals With Fanconi Anemia

Fanconi Anemia

United States
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine; University of...

Terminated

Use of Rft5-Dga to Deplete Alloreactive Cells for Pts With Fanconi Anemia After Haploidentical SCT (RAFHAS)

FANCONI ANEMIA

United States
University of Minnesota

Completed

Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia

United States
University of California, San Francisco

Recruiting

NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients (NEPH-ROSIS)

Cirrhosis | Acute Kidney Injury | Portal Hypertension | Hepatorenal Syndrome | Acute Tubule Necrosis | Prerenal Failure

United States
Children's Hospital Medical Center, Cincinnati

Not yet recruiting

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI (Taking Focus 2)

Acute Kidney Injury | Acute Kidney Injury Due to Sepsis | Neonatal Sepsis

United States
Assistance Publique Hopitaux De Marseille

Recruiting

Comparison of ANCA and Anti-GBM Auto-antibodies Removal Kinetics Between Plasma Exchanges and Immunoadsorption in Patients With ANCA-associated Vasculitis or Anti-GBM Disease (CINEVAS)

Kidney Failure, Acute

France
Metro International Biotech, LLC

Completed

Phase 2a MIB-626 vs. Placebo COVID-19

Covid19 | Stage 1 Acute Kidney Injury

United States
Università degli Studi di Ferrara

Completed

PEEP-induced Changed in RRI as Physiological Background of Ventilator-induced Kidney Injury (PRE-VIKI)

Acute Kidney Injury | Respiratory Distress Syndrome, Adult | Respiration, Artificial

Italy
Novartis Pharmaceuticals

Completed

Phase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Renal Cancer | Hepatocellular Cancer

Taiwan, Germany, Italy, Austria, Switzerland, Hong Kong, Japan, Canada, United States
Masonic Cancer Center, University of Minnesota

Completed

Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia

Fanconi Anemia

United States
Leiden University Medical Center
Radboud University Medical Center; Health Holland; Dutch Kidney Foundation

Completed

Dietary Interventions on Glycocalyx Dimensions in South Asian Patients With Diabetic Nephropathy. (Glycotreat)

Glucose Metabolism Disorders | Kidney Diseases | Diabetes Mellitus | Diabetic Nephropathies | Albuminuria | Microalbuminuria | Type2 Diabetes Mellitus | Diabetic Nephropathy Type 2 | Diabetic Complications Renal | South Asian

Netherlands
Yonsei University

Unknown

The Impact of Sleep-disordered Breathing on the Incidence of Postoperative Acute Kidney Injury in Patients Undergoing Valvular Heart Surgery

Valvular Heart Disease

Korea, Republic of
Masonic Cancer Center, University of Minnesota

Terminated

Stem Cell Transplantation for Fanconi Anemia

Fanconi Anemia

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Gene Function in Bone Marrow Cells From Patients With Fanconi Anemia and From Healthy Participants

Fanconi Anemia

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Miltenyi Biotec, Inc.

Completed

Hematopoietic Stem Cell Transplantation for Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using Total Body Irradiation, Cyclophosphamide and Fludarabine

Fanconi Anemia

United States
Xiang Guang-da

Unknown

Short-Term Alpha Lipoic Acid Therapy for Prevention of Contrast-induced Acute Kidney Injury and Endothelial Dysfunction in Type 2 Diabetes

Acute Kidney Injury | The Changes of Plasma Creatinine | The Changes of Plasma Free Radicals | The Changes of Endothelium-dependent Arterial Dilation

China
Mario Negri Institute for Pharmacological Research

Terminated

Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency (SIRENA-II)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Italy
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Fanconi's Anemia

Fanconi's Anemia

United States
Dana-Farber Cancer Institute

Unknown

Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia

Fanconi's Anemia

United States
National Cancer Institute (NCI)

Completed

Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Ovarian Carcinoma | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Renal Cell Carcinoma | Stage III Renal Cell Cancer | Stage IV Skin Melanoma | Recurrent Non-Small Cell... and other conditions

Canada
Postgraduate Institute of Medical Education and...

Recruiting

Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Refractory Ascites

Acute-On-Chronic Liver Failure | Ascites | Acute Kidney Injury | Cirrhosis, Liver | Refractory Ascites

India
Assistance Publique - Hôpitaux de Paris

Recruiting

Dental Implants in Patients With X-linked Hypophosphatemia (IMPLANTS-XLH)

X-linked Hypophosphatemia

France
University of Giessen

Active, not recruiting

Perioperatively Assessed Biomarker I-FABP Level for Prediction of Acute Mesenteric Ischemia and Its Correlation With Acute Kidney Injury, Followed by Extracorporeal Circulation (aMIKI) (aMIKI)

Acute Kidney Injury | Acute Mesenteric Ischemia | Cardiac Surgery With Cardiopulmonary Bypass | Non-Occlusive Mesenteric Ischaemia

Germany
Icahn School of Medicine at Mount Sinai
Johns Hopkins University; University of Michigan; New Jersey Medical School; Yale...

Active, not recruiting

Kidney Disease After COVID-19

COVID-19 | Acute Kidney Injury | Chronic Kidney Injury

United States
Wuerzburg University Hospital
Kyowa Kirin, Inc.

Completed

Anti-FGF23 (Burosumab) in Adult Patients With XLH (BurGER)

X-linked Hypophosphatemia

Germany
Rocket Pharmaceuticals Inc.

Active, not recruiting

Lentiviral-mediated Gene Therapy for Pediatric Patients With Fanconi Anemia Subtype A

Fanconi Anemia Complementation Group A

Spain

Clinical Trials on Augmented Renal Clearance

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Guatemala

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations