Clinical Trials on BCR-ABL in China

Total 34575 results

Shanghai Jiao Tong University School of Medicine

Terminated

NeoMET Study in Neoadjuvant Treatment of Breast Cancer (NeoMET)

Safety | pCR Rate | BCT Rate

China
Shenzhen Second People's Hospital

Recruiting

Dose Reduced Dasatinib (70 mg Daily) as First-line Treatment for Newly Diagnosed CML-CP

Chronic Myeloid Leukemia | Dasatinib | BCR-ABL

China
Shenzhen Second People's Hospital

Recruiting

TKI Discontinuation in CML Patients of China (TFR_china)

Leukemia | Myelogenous | Chronic | BCR-ABL (Breakpoint Cluster Region-abelson Murine Leukemia) | Positive

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

Bioequivalence Study of Mesylate Imatinib Capsule in Chronic Myeloid Leukemia Body

Chronic Myeloid Leukemia

China
First Affiliated Hospital of Harbin Medical University

Unknown

Evaluation of the Therapeutic Effect of HU Pulse Therapy for CML Patients (HU)

Leukemia, Chronic Myeloid

China
Nanfang Hospital of Southern Medical University

Recruiting

Dasatinib Down-regulates the Expression of PD-1 and Enhances Killing pH + Leukemia Stem Cells

Chronic Myeloid Leukemia

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

A Bioequivalence Study of Dasatinib Tablet

Leukemia, Myelogenous, Chronic

China
Nanfang Hospital of Southern Medical University

Unknown

Vitro Study of Tigecycline to Treat Chronic Myeloid Leukemia

Chronic Myeloid Leukemia

China
Ascentage Pharma Group Inc.
HealthQuest Pharma Inc.

Completed

The Absorption, Metabolism and Excretion of [14C] HQP1351 in Humans

Chronic Myeloid Leukemia (CML)

China
Bristol-Myers Squibb

Completed

Effectiveness of Dasatinib in Adult Patients With Chronic Myeloid Leukemia in China: A Multicenter, Registry Study

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

China
Affiliated Hospital of Nantong University

Recruiting

FLOR3 Gene Polymorphism in Predicting Outcomes of Tyrosine Kinase Inhibitor（TKI）Stopping in Chronic Myeloid Leukemia (NTU-CML-001)

CML | Treatment-free Remission | Folate

China
Ascentage Pharma Group Inc.
HealthQuest Pharma Inc.

Completed

Pharmacokinetics Profiles of HQP1351 Under Fasting and High-fat Meals in Patients With Chronic Myeloid Leukemia (CML)

Chronic Myeloid Leukemia, Chronic Phase

China
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

A Real World Study of the Efficacy and Safety of Flumatinib Versus Imatinib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

CML, Chronic Phase

China
Shenzhen Second People's Hospital
Dongguan People's Hospital; Zhongshan People's Hospital, Guangdong, China; The... and other collaborators

Recruiting

Nilotinib for First-line Newly Diagnosed CML-CP Patients

Chronic Myeloid Leukemia, Chronic Phase | Nilotinib

China
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Unknown

A Phase II Study to Evaluate the Efficacy and the Safety of Flumatinib in CML-AP or CML-BP Patients

Chronic Myelogenous Leukemia

China
xuna

Recruiting

A Study for PRO of CML in Real Word (Case-Only)

CML (Chronic Myelogenous Leukemia)

China
Shenzhen Second People's Hospital

Recruiting

The Efficacy and Safety of Switching to Flumatinib Versus Dasatinib After Imatinib-related Low-grade Adverse Events in CML-CP Patients

Chronic Myeloid Leukemia in Chronic Phase

China
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

A Study of the Efficacy and Safety of Flumatinib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase.

CML, Chronic Phase

China
Peking University People's Hospital
Henan Cancer Hospital; Wuhan Union Hospital, China; Zhejiang University; Peking... and other collaborators

Not yet recruiting

The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP

Chronic Myeloid Leukemia

China
Shenzhen TargetRx, Inc.
Peking University People's Hospital

Recruiting

TGRX-678 Chinese Phase I in Chronic Myelogenous Leukemia (CML) Patients

Chronic Myelogenous Leukemia

China
Shenzhen Second People's Hospital

Recruiting

Treatment With Olverembatinib in CML-CP Patients Who Failed to at Least Two Previously Administered Second-generation TKIs.

Chronic Myeloid Leukemia, Chronic Phase | Olverembatinib | Tyrosine Kinase Inhibitors

China
Shenzhen Second People's Hospital
Hainan General Hospital; Sanya Central Hospital; First Affiliated Hospital of... and other collaborators

Recruiting

Flumatinib in CML-CP Patients With Ph+ Post Imatinib Failure

Chronic Myeloid Leukemia, Chronic Phase | Flumatinib | Imatinib

China
Il-Yang Pharm. Co., Ltd.

Active, not recruiting

Randomized Evaluation of Radotinib Versus Imatinib in Phase III Study for Efficacy With Chinese Patients (RERISE China)

Chronic Myeloid Leukemia, Chronic Phase

China
Nanfang Hospital of Southern Medical University

Recruiting

Flumatinib Efficacy and Safety for New Diagnosed Chronic Phase Chronic Myeloid Leukemia

Validity and Safety

China
TCRx Therapeutics Co.Ltd

Recruiting

KSX01-TCRT Injection Project in Solid Tumors

Refractory Solid Tumors | Relapsed Solid Tumors | TCR-T Cells

China
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

A Study of HS-10382 in Patients With Chronic Myeloid Leukemia.

CML, Chronic Phase | CML, Accelerated Phase

China
TCRx Therapeutics Co.Ltd

Recruiting

KSH01-TCRT Solid Tumors (KSH01-TCRT)

Refractory Solid Tumors | Relapsed Solid Tumors | TCR-T Cells

China
Bristol-Myers Squibb

Completed

Study of Chinese Newly Diagnosed Participants With Philadelphia Chromosome-Positive (Ph+) Chronic Myeloid Leukemia in Chronic Phase (CML-CP)

Chronic Myeloid Leukemia | Philadelphia Chromosome | Chronic Myeloid Leukemia in Chronic Phase

China
Nanfang Hospital of Southern Medical University
Xiangya Hospital of Central South University; Tongji Hospital; Guangzhou First... and other collaborators

Completed

Allo-HSCT With Alternative Donor in Treatment of Hematologic Malignancy

Chronic Myeloid Leukemia | Acute Leukemia | Myelodysplastic Syndrome

China
Zhongda Hospital

Recruiting

Study of Efficacy and Safety of Flumatinib Combined With Chemotherapy in Ph Positive ALL

BCR-ABL1 Fusion Protein Expression | Acute Lymphocytic Leukemia, Adult B-Cell

China
iCell Gene Therapeutics
Peking University Shenzhen Hospital; iCAR Bio Therapeutics Ltd.; Chengdu Military...

Unknown

CD123-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myeloid Leukemia | Hematologic Malignancy | Myeloproliferative Neoplasm

China
The First Affiliated Hospital of Soochow University

Recruiting

Flumatinib Versus Nilotinib for Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia

CML, Chronic Phase; TKI

China
iCell Gene Therapeutics
The General Hospital of Western Theater Command; Peking University Shenzhen... and other collaborators

Recruiting

CLL1-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myeloid Leukemia | Hematologic Malignancy | Myeloproliferative Neoplasm

China
The Affiliated Hospital of Qingdao University

Recruiting

Prognostic Value of Myosteatosis and Creatinine-to-cystatin C Ratio in Patients With Pancreatic Ductal Adenocarcinoma

Pancreatic Ductal Adenocarcinoma | Myosteatosis | Skeletal Muscle Radiodensity | Scr/CysC Ratio

China
Wuhan Union Hospital, China

Recruiting

Evaluating Efficacy and Safety of Flumatinib for Chronic Phase Chronic Myeloid Leukemia(CML-CP) Without Optimal Response (Warning,Failure) to Imatinib or Dasatinib

CML-CP; Mutation;Suboptimal Response or Failure in TKI

China
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase II Study of Flumatinib Versus Imatinib to Treat Philadelphia Chromosome Positive Chronic Myelogenous Leukemia

Myelogenous Leukemia, Chronic

China
Zhongda Hospital

Recruiting

Clinical Study of TCR-like CAR-T Cell Targeted MSLN in the Treatment of Ovarian Cancer

Safety and Efficacy of TCR-like CAR-T

China
Shandong University

Withdrawn

Cell Cycle Regulatory Gene Study in Patients With Myeloproliferative Disorders

Myeloproliferative Disorders | Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Chronic Myeloid Leukemia

China
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Nilotinib vs. Imatinib in the Treatment of Newly Diagnosed Chinese Ph+ CML-CP Patients

Chronic Myeloid Leukemia

China
Telix Pharmaceuticals (Innovations) Pty Limited
Grand Pharmaceutical (China) Co., Ltd.

Recruiting

68Ga-PSMA-11 Efficacy in Detecting BCR Prostate Cancer in Chinese Patients

Prostate Cancer | Biochemical Recurrence of Malignant Neoplasm of Prostate | BCR Prostate Carcinoma

China
Ascentage Pharma Group Inc.

Active, not recruiting

A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation

Chronic Myeloid Leukemia - Accelerated Phase

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

A Study of Dasatinib as First-line Treatment for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia (CML-CP)

Chronic Myelogenous Leukemia - Chronic Phase

China
Ascentage Pharma Group Inc.

Active, not recruiting

A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Chronic Phase With T315I Mutation

Chronic Myeloid Leukemia, Chronic Phase

China
Nanfang Hospital of Southern Medical University

Recruiting

Decitabine and HQP1351-based Chemotherapy Regimen for the Treatment Advanced CML (Case-Only)

Chronic Myeloid Leukemia in Myeloid Blast Crisis | Chronic Myeloid Leukaemia Transformation | Chronic Myeloid Leukemia - Accelerated Phase | Chronic Myeloid Leukemia in Lymphoid Blast Crisis

China
Junmin Li

Suspended

Phase III Study of Compound Formula Realgar-Indigo Naturalis Plus Imatinib Versus Placebo Plus Imatinib in Adult CML-CP Patients With Ph+

Chronic Myelogenous Leukemia

China
Zhang Rui

Recruiting

Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients

Rectal Cancer | Surgery | Almost-cCR

China
Shenzhen Geno-Immune Medical Institute
The Seventh Affiliated Hospital of Sun Yat-sen University; Shenzhen Children...

Recruiting

Multi-CAR-T Cells Targeting B Cell Lymphomas

B Cell Lymphoma (BCL)

China
Novartis Pharmaceuticals

Completed

A Study of Imatinib and Nilotinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase

Leukemia

China
The First Affiliated Hospital of Soochow University

Completed

Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Philadelphia Chromosome | Mixed Phenotype Acute Leukemia

China

Clinical Trials on BCR-ABL in China

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