Clinical Trials on BCR-JAK2 Fusion Protein Expression

Total 176 results

William Shomali
Incyte Corporation

Recruiting

Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

Eosinophilia | Hypereosinophilic Syndrome | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells | Splenomegaly | Hepatomegaly | Chronic Eosinophilic Leukemia, Not Otherwise Specified | JAK2 Gene Mutation | BCR-JAK2 Fusion Protein Expression | Blasts 20 Percent or Less of Peripheral Blood White... and other conditions

United States
Centre Leon Berard

Recruiting

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING) (TRacKING)

Cancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditions

France, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
Assiut University

Unknown

PCM1-JAK2 in Therapy Related Neoplasms

Detection of PCM1-JAK2 Fusion Gene by FISH in the Two Types of t-MDS/AML and Relationship Between PCM1-JAK2 Fusion Gene and Cumulative Dose, Dose Intensity
National Taiwan University Hospital
National Health Research Institutes, Taiwan

Recruiting

Cancer Fusion Hybrids and Desmoplasia

Bone Marrow Cells | Fusion Protein Expression

Taiwan
Zhongda Hospital

Recruiting

Study of Efficacy and Safety of Flumatinib Combined With Chemotherapy in Ph Positive ALL

BCR-ABL1 Fusion Protein Expression | Acute Lymphocytic Leukemia, Adult B-Cell

China
Changhai Hospital

Unknown

AML1-ETO Acute Myeloid Leukemia With Fludarabine and Cytarabine Chemotherapy

Acute Myeloid Leukemia | AML1-ETO Fusion Protein Expression

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Dasatinib in Treating Participants With Philadelphia Positive or BCR-ABL Positive Acute Lymphoblastic Leukemia.

Acute Lymphoblastic Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia Chromosome Positive | Recurrent Acute Lymphoblastic Leukemia | t(9;22) | BCR-ABL1 Fusion Protein Expression

United States
University of California, San Francisco

Terminated

Capmatinib, Ceritinib, Regorafenib, or Entrectinib in Treating Patients With BRAF/NRAS Wild-Type Stage III-IV Melanoma

ALK Fusion Protein Expression | Stage III Cutaneous Melanoma | Stage IIIA Cutaneous Melanoma | Stage IIIB Cutaneous Melanoma | Stage IIIC Cutaneous Melanoma | Stage IV Cutaneous Melanoma | ROS1 Fusion Positive | BRAF wt Allele | Invasive Skin Melanoma | MET Fusion Gene Positive | NRAS wt Allele | NTRK1 Fusion... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Takeda; Amgen

Recruiting

Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia Chromosome Positive | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | t(9;22) | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | BCR-ABL1...

United States
Sameek Roychowdhury
National Cancer Institute (NCI)

Withdrawn

Brigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Cancers

Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | ALK Gene Mutation | Metastatic Malignant Neoplasm in the Brain | Advanced Malignant Neoplasm | ALK Fusion Protein Expression | Metastatic Malignant Neoplasm in the Central Nervous System | ROS1 Gene Mutation | ALK Gene... and other conditions

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Recruiting

Prophylactic Peptide Vaccine in Advanced ALK+ NSCLC

NSCLC Stage IV | ALK Fusion Protein Expression

United States
Mansoura University

Completed

JAK2 Mutation May Predict Response and Guide First Line Treatment in Rheumatoid Arthritis

Response Assessment in Newly Diagnosed RA Patients at 3rd Month Was Evaluated by DAS28 and ACR in Relation to JAK Expression

Egypt
Sichuan University
Betta Pharmaceuticals Co., Ltd.

Not yet recruiting

A Study Comparing Ensatinib Versus Platinum-Based Chemotherapy as Adjuvant Treatment for Stage II-IIIA ALK -Positive Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer | ALK Fusion Protein Expression | Adjuvant Therapy
University of Missouri-Columbia

Recruiting

Baker Gordon Syndrome Natural History Study (BAGOS)

Epilepsy, Generalized | Sleep Disorder | Rare Diseases | Development Delay | Motor Delay | Autism or Autistic Traits | SYT-SSX Fusion Protein Expression

United States
Central Jutland Regional Hospital

Completed

Lumbar Spinal Fusion - Web-based Platform Targeting Anxiety and Depression

Depression | Anxiety | Lumbar Spine Fusion

Denmark
Instituto Mexicano del Seguro Social
Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado

Completed

Effect of Ketamine in Depressive Symptoms of Elderly Patients With Visual Impairment.

Ketamine | Depression in Old Age

Mexico
Anglia Ruskin University

Completed

Music Listening for Wellbeing in Adults With Acquired Visual Impairment

Depression | Stress | Anxiety | Visual Impairment | Low Vision | Emotional Adjustment

United Kingdom
Thomas Jefferson University
Johns Hopkins University; Dartmouth-Hitchcock Medical Center

Completed

Low Vision Depression Prevention Trial for Age Related Macular Degeneration (VITAL)

Depression | Age-related Macular Degeneration

United States
Vivoxid Ltd

Completed

Bioactive Glass as Bone Graft Substitute in Operative Treatment of Bone - a 10 Years Follow-up Study

Spinal Fusion | Depressed Lateral Condyle Fracture | Benign Bone Tumour Cavity

Finland
Peking University Cancer Hospital & Institute

Completed

Gene Expression Profiling of Breast Cancer Cells Predict the Response of Malignant Pleural Effusion (GMPE)

Breast Neoplasms | Neoplasm Metastasis | Immunotherapy | Gene Expression Profiling

China
Bristol-Myers Squibb

Completed

Frequency and Severity of Pleural Effusion Associated With the Use of Dasatinib in Patients With Chronic Myeloid Leukemia. A Descriptive, Mexican Multicenter Study (PASS)

Leukemia
Lawson Health Research Institute
The Art of Living Foundation

Withdrawn

Virtual Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers

Depression | Quality of Life | Sleep | Anxiety | Caregiver Burnout | Vision; Disorder, Loss
University of Bari

Recruiting

Lactobacillus Reuteri Strain Combination in Children Treated With PPI

Probiotic | Gastric Lesion | Proton Pump Inhibitor Adverse Reaction

Italy
Johns Hopkins University

Completed

Yoga for Persons With Severe Visual Impairment (RPY)

Depression | Stress | Anxiety | Sleep Disturbance | Balance Impairment

United States
Barbara Ann Karmanos Cancer Institute

Completed

DISCO Application for the Improvement of Financial Outcomes in Patients With Hematologic Cancer

Chronic Lymphocytic Leukemia | Plasma Cell Myeloma | Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Lymphocyte Infusion in Treating Patients With Persistent, Relapsed, or Progressing Cancer After Donor Hematopoietic Cell Transplant

Recurrent Hodgkin Lymphoma | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Non-Hodgkin Lymphoma | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Plasma Cell Myeloma

United States, Germany, Italy
Oncoethix GmbH

Completed

A Dose-Finding Study of Birabresib (MK-8628), a Small Molecule Inhibitor of the Bromodomain and Extra-Terminal (BET) Proteins, in Adults With Selected Advanced Solid Tumors (MK-8628-003)

Triple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma | Castrate-resistant Prostate Cancer | CRPC | NUT Midline Carcinoma | Non-small Cell Lung Cancer With Rearranged ALK Gene/Fusion Protein or KRAS Mutation
Fundacio Salut i Envelliment UAB

Not yet recruiting

Effectiveness of AMICOPE Intervention to Maintain Self-Perceived Health and Intrinsic Capacity in Older People (EFICIS)

Depressive Symptoms | Hearing Loss | Cognitive Decline | Visual Impairment | Nutrition, Healthy | Mobility
National Cancer Institute (NCI)

Completed

Ipilimumab or Nivolumab in Treating Patients With Relapsed Hematologic Malignancies After Donor Stem Cell Transplant

Recurrent Hodgkin Lymphoma | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Recurrent Non-Hodgkin Lymphoma | Recurrent Acute Lymphoblastic Leukemia | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Plasma Cell Myeloma | Myeloproliferative Neoplasm | Recurrent... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Recurrent Hodgkin Lymphoma | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Aplastic Anemia | Recurrent Non-Hodgkin... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant

Acute Myeloid Leukemia | Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Plasma Cell Myeloma | Myelodysplastic/Myeloproliferative Neoplasm | Graft Versus Host Disease | Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States, Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Recurrent Hodgkin Lymphoma | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Recurrent Non-Hodgkin Lymphoma | Recurrent Acute Lymphoblastic Leukemia | Recurrent Chronic... and other conditions

United States
Roswell Park Cancer Institute

Active, not recruiting

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Myeloproliferative Neoplasm | Minimal Residual Disease | Graft Versus Host Disease | Severe Aplastic Anemia | Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic Leukemia... and other conditions

United States
Chinese University of Hong Kong
Roche Diagnostics

Recruiting

Comparing N-terminal-proB-type Natriuretic Peptide With Other Criteria in Pleural Fluid Analysis

Heart Failure | Infections | Renal Failure | Cirrhosis | Fluid Overload | Pleural Effusion | Malignant Neoplasm | Hypoalbuminemia

Hong Kong
Tragara Pharmaceuticals, Inc.

Completed

Phase 1 Study of TG02 Citrate in Patients With Advanced Hematological Malignancies (TG02-101)

Multiple Myeloma | AML | Blast Crisis | MDS | ALL

United States
University Hospital, Antwerp

Unknown

Efficacy of Dendritic Cell Therapy for Myeloid Leukemia and Myeloma

Acute Myeloid Leukemia | Multiple Myeloma | Chronic Myeloid Leukemia

Belgium
Milton S. Hershey Medical Center

Terminated

Clofarabine and Non-Myeloablative Allogeneic Hematopoietic Transplantation

Lymphoma | Leukemia | Multiple Myeloma | Hodgkin's Lymphoma | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia

United States
Ohio State University Comprehensive Cancer Center

Active, not recruiting

Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study

Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Aplastic Anemia | Myeloproliferative Neoplasm | Chronic Myelogenous Leukemia...

United States
Iolanda Costa Galinha
DGArtes - Direção Geral das Artes; CIS-Iscte - Centro de Investigação e Intervenção...

Completed

Singing Groups for Seniors: Well-Being, Cognitive Function and Health (Sing4Health)

Depression | Quality of Life | Body Weight | Stress | Sleep | Anxiety | Blood Pressure | Cognitive Function | Blood Glucose | Loneliness | Physical Function | Medication Compliance | Balance | Memory | Biomarker | Well-Being | Respiratory Function | Social Identification | Cholesterol | C-reactive Protein | Erythrocyte Sedimentation Rate and other conditions

Portugal
Washington University School of Medicine

Completed

Abdominal CT to Predict the Risk of Acute Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation (GVHD)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Multiple Myeloma | Leukemia, Myelogenous, Chronic

United States
Bristol-Myers Squibb

Withdrawn

Safety Study of Anti-Programmed Death-Ligand 1 in Hematologic Malignancy

Multiple Myeloma | Hodgkin Lymphoma | Non-Hodgkin's Lymphoma | Chronic Myelogenous Leukemia
Fred Hutchinson Cancer Center

Active, not recruiting

Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease

Follicular Lymphoma | Acute Myeloid Leukemia | Myelofibrosis | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Total-Body Irradiation With or Without Fludarabine Phosphate Followed By Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Hematopoietic and Lymphoid Cell Neoplasm | Diffuse Large B-Cell Lymphoma | Refractory Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Plasma Cell Myeloma | Refractory Chronic Lymphocytic Leukemia | Myelodysplastic/Myeloproliferative Neoplasm | Chronic Phase Chronic Myelogenous... and other conditions

United States, Germany, Italy
University of Tennessee
AstraZeneca; Vanderbilt University Medical Center

Recruiting

Oral Adherence in Hematological Oncology Agents and Impact on Comorbid Therapy Adherence

Multiple Myeloma | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Multiple Chronic Conditions

United States
Masonic Cancer Center, University of Minnesota

Terminated

Post Transplant Donor Lymphocyte Infusion

Multiple Myeloma | AML | Myelodysplastic Syndrome | Leukemia, Lymphocytic, Acute | Lymphomas | Leukemia, Myeloid, Chronic | Leukemia, Lymphocytic, Chronic

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Terminated

Reduced Intensity Preparative Regimen Followed by Stem Cell Transplant (FAB)

Lymphoproliferative Disorders | Hematologic Diseases | Multiple Myeloma | Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Plasma Cell Dyscrasia | Myelodysplastic and Myeloproliferative Disorders

United States
M.D. Anderson Cancer Center
Eligix

Terminated

CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell Transplantation

Multiple Myeloma | Chronic Lymphocytic Leukemia | Chronic Myelogenous Leukemia | Non Hodgkin's Lymphoma | Hodgkin's Disease

United States
Northwestern University
National Cancer Institute (NCI)

Completed

Bone Marrow Transplantation in Treating Patients With Multiple Myeloma, Chronic Phase Chronic Myelogenous Leukemia, or Agnogenic Myeloid Metaplasia

Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Personalized NK Cell Therapy in CBT

Recurrent Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Myelodysplastic Syndrome... and other conditions

United States
University Hospital Tuebingen
Robert Bosch Hospital Stuttgart

Recruiting

Auricular Acupuncture in Patients With Multiple Myeloma (MY_ACU)

Depression | Pain | Fatigue | Multiple Myeloma

Germany

Clinical Trials on BCR-JAK2 Fusion Protein Expression

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